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The map label for this gene is ahpC [C]

Identifier: 119898954

GI number: 119898954

Start: 2938853

End: 2939512

Strand: Reverse

Name: ahpC [C]

Synonym: azo2663

Alternate gene names: 119898954

Gene position: 2939512-2938853 (Counterclockwise)

Preceding gene: 119898956

Following gene: 119898945

Centisome position: 67.17

GC content: 63.64

Gene sequence:

>660_bases
ATGTCGCTGCGCATCAACGATATCGCCCCCGACTTCACCGCCGAAACCACCCAGGGCACCATCCGCTTCCATGACTGGAT
CGGCGACGGCTGGGCCATCCTGTTCTCGCATCCCAAGGACTTCACCCCGGTGTGCACCACCGAGCTGGGCTACATGGCCA
AGATCGAGCCGGAATTCCGCCGGCGCAACTGCAAGATCATCGGGCTGAGTGTGGACCCGGTGGACAACCACGCGCGGTGG
GCGAAGGACATCGAGGAAACCCAGGGCTATCTGCCGGCCTACCCGATGATCGGCGACCCCAATCTGGAAGTGGCCAAGCT
CTACAACATGCTGCCGGCTGAAGAACCGGGCACCTCCGAAGGCCGCACGCCGGCCAACAACGCCACCGTGCGCTCGGTGT
TCGTGATCGGCCCGGACAAGCGCATCAAGCTGATGTTGACCTATCCGATGACCACCGGCCGCAACTTCGACGAAATCCTG
CGGGTGCTCGATTCGATGCAACTCACCGCGGCGCACAAGGTGGCGACCCCGGTGAACTGGAAGCATGGCGAGGACGTGAT
CATCGCCGGCTCGGTGTCCGACGACGACGCGAAGACGCTCTTCCCGCAGGGCTGGAAAGCGCCCAAGCCCTACCTGCGCA
TCGTCAAGCAACCCGGCTGA

Upstream 100 bases:

>100_bases
CGTGCGCGTTCGCTTTCGCTGCCTTGGCAAGCGCGGAGGGCGGACCTATACCGAGGGGAGAACCGATCCACGGTCGCGCA
CAACAGAGGAGGAGACCACC

Downstream 100 bases:

>100_bases
GGCGGCTGCGCCAACCTGCCGCGCCCGCGCCGGGCCGAGGGTGCGGCGCAGGCGCGGTTGCTGTCGGCTTTACGCGGCTT
CGGGCGGCGTTTCGGTCTTG

Product: peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSLRINDIAPDFTAETTQGTIRFHDWIGDGWAILFSHPKDFTPVCTTELGYMAKIEPEFRRRNCKIIGLSVDPVDNHARW
AKDIEETQGYLPAYPMIGDPNLEVAKLYNMLPAEEPGTSEGRTPANNATVRSVFVIGPDKRIKLMLTYPMTTGRNFDEIL
RVLDSMQLTAAHKVATPVNWKHGEDVIIAGSVSDDDAKTLFPQGWKAPKPYLRIVKQPG

Sequences:

>Translated_219_residues
MSLRINDIAPDFTAETTQGTIRFHDWIGDGWAILFSHPKDFTPVCTTELGYMAKIEPEFRRRNCKIIGLSVDPVDNHARW
AKDIEETQGYLPAYPMIGDPNLEVAKLYNMLPAEEPGTSEGRTPANNATVRSVFVIGPDKRIKLMLTYPMTTGRNFDEIL
RVLDSMQLTAAHKVATPVNWKHGEDVIIAGSVSDDDAKTLFPQGWKAPKPYLRIVKQPG
>Mature_218_residues
SLRINDIAPDFTAETTQGTIRFHDWIGDGWAILFSHPKDFTPVCTTELGYMAKIEPEFRRRNCKIIGLSVDPVDNHARWA
KDIEETQGYLPAYPMIGDPNLEVAKLYNMLPAEEPGTSEGRTPANNATVRSVFVIGPDKRIKLMLTYPMTTGRNFDEILR
VLDSMQLTAAHKVATPVNWKHGEDVIIAGSVSDDDAKTLFPQGWKAPKPYLRIVKQPG

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=227, Percent_Identity=53.3039647577093, Blast_Score=225, Evalue=3e-59,
Organism=Homo sapiens, GI4505591, Length=190, Percent_Identity=29.4736842105263, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32455266, Length=190, Percent_Identity=29.4736842105263, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32455264, Length=190, Percent_Identity=29.4736842105263, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32189392, Length=205, Percent_Identity=27.8048780487805, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI5453549, Length=169, Percent_Identity=26.6272189349112, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI32483377, Length=151, Percent_Identity=27.8145695364238, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI5802974, Length=151, Percent_Identity=27.8145695364238, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI1786822, Length=155, Percent_Identity=28.3870967741935, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=234, Percent_Identity=38.4615384615385, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32565831, Length=171, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204376, Length=171, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17554494, Length=161, Percent_Identity=26.0869565217391, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319407, Length=218, Percent_Identity=51.8348623853211, Blast_Score=218, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24581278, Length=224, Percent_Identity=48.2142857142857, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24652436, Length=207, Percent_Identity=46.8599033816425, Blast_Score=198, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24652434, Length=207, Percent_Identity=45.8937198067633, Blast_Score=196, Evalue=1e-50,
Organism=Drosophila melanogaster, GI17975518, Length=207, Percent_Identity=45.8937198067633, Blast_Score=195, Evalue=2e-50,
Organism=Drosophila melanogaster, GI17157991, Length=171, Percent_Identity=30.4093567251462, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24641739, Length=171, Percent_Identity=30.4093567251462, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357347, Length=199, Percent_Identity=29.1457286432161, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17738015, Length=185, Percent_Identity=25.9459459459459, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656348, Length=159, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17864676, Length=159, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24539; Mature: 24408

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRINDIAPDFTAETTQGTIRFHDWIGDGWAILFSHPKDFTPVCTTELGYMAKIEPEFR
CCEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEECCCCCEEEECCHHHH
RRNCKIIGLSVDPVDNHARWAKDIEETQGYLPAYPMIGDPNLEVAKLYNMLPAEEPGTSE
HCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
GRTPANNATVRSVFVIGPDKRIKLMLTYPMTTGRNFDEILRVLDSMQLTAAHKVATPVNW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
KHGEDVIIAGSVSDDDAKTLFPQGWKAPKPYLRIVKQPG
CCCCCEEEECCCCCCCCHHCCCCCCCCCCHHHEEEECCC
>Mature Secondary Structure 
SLRINDIAPDFTAETTQGTIRFHDWIGDGWAILFSHPKDFTPVCTTELGYMAKIEPEFR
CEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCEECCCCCEEEECCHHHH
RRNCKIIGLSVDPVDNHARWAKDIEETQGYLPAYPMIGDPNLEVAKLYNMLPAEEPGTSE
HCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCC
GRTPANNATVRSVFVIGPDKRIKLMLTYPMTTGRNFDEILRVLDSMQLTAAHKVATPVNW
CCCCCCCCEEEEEEEECCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
KHGEDVIIAGSVSDDDAKTLFPQGWKAPKPYLRIVKQPG
CCCCCEEEECCCCCCCCHHCCCCCCCCCCHHHEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]