Click here to switch to the map view.

The map label for this gene is hrcA [H]

Identifier: 119898872

GI number: 119898872

Start: 2861000

End: 2862028

Strand: Direct

Name: hrcA [H]

Synonym: azo2581

Alternate gene names: 119898872

Gene position: 2861000-2862028 (Clockwise)

Preceding gene: 119898869

Following gene: 119898873

Centisome position: 65.38

GC content: 64.53

Gene sequence:

>1029_bases
ATGAACCCGCTCGACGCCCGCTCCCAGATCCTGCTCAAGACGCTGATCGAACGCTATATCGCGGACGGCCAGCCGGTCGG
GTCGCGTGCGCTGTCCCGTTATTCCGGGCTGGAACTATCCCCGGCGACGGTGCGCAACGTCATGAGCGATCTCGAAGAGA
TGGGCTTCATCGCCAGCCCGCACACCTCCGCGGGGCGCGTGCCCACGGCGCTCGGCTATCGTTTCTTCGTCGACGCCCTG
CTGACCGTGCATCCGATGGACCGCGTGAGGGTGGAAGAACTGCAGGGGCAGTTGCTGCCCGACCAGCCGCAGCGGCTGAT
CAGCTCCGCGTCGCACCTGCTGTCGCAACTCACCCAGTTCGCCGGCGTCGTGGTGGCGCCGCGCAAGGAAGCGGTGCGGA
TCCGACAGATCGAATTCATCCGCCTGTCCGAATCGCGCATCCTGCTGATCATCGTCACCGCGGCCGGGGACGTGCAGAAC
CGCATCCTGCTCACCAAGCGGGCGTATTCCGCGGTCGAACTGAGCAATGCCGCGCAGCACCTGAATGAACATTTCGCCGG
GCTGTCCTTCGACGAGATTCGCACCCGCGTCCAGGACGAGCTGAGGCAGCTCCACAGCGACATGAGCGAGCTGATGACCG
CGACGGTCGAAGCCGGCACCGAAGCGGCGGCCGAAACCGGCAACAACTACGTCATCTCGGGTGAAACCAACCTGCTCGAA
GTCGAAGACCTGTCATCCAACATGTCGCGCCTGCGCGAACTCTTCAAACTGTTCGAGCAGAAAACCGGACTGATGCAGCT
GCTGGACCTCTCCAACCGCGCCCAAGGCGTGCAGATCTTCATCGGCGGTGAGTCCGGCCTCGCGCCGCTCGACGGCTGCA
GCGTCATCACCTCCAGTTATGAAGTGGACGGCGAGGTCGTCGGCTCGGTCGGCGTCATCGGCCCCACGCGCATGGCGTAC
GACCGGGTCATCCCGATCGTCGACATCACCGCGCGCCTGCTGTCGAACGCGCTGTCGTCCAATCACTGA

Upstream 100 bases:

>100_bases
CGCGGATTAAACCACATTCATGTATCGGCTTGGCGCGCACTGACGCTTGGCAGCAGCCTGTGCTCTTCCCTAGAATCAGG
CACTATCCTTGCCTACTGCC

Downstream 100 bases:

>100_bases
ATCGCTGCCCGCGCCGCGGGCCGACAACCCAATCCCGGAAGATCCCATGGCCCGATTCTGGACCGAAGCCCCGCATCGCC
ACGGCAGCACCGCGCGCACC

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNPLDARSQILLKTLIERYIADGQPVGSRALSRYSGLELSPATVRNVMSDLEEMGFIASPHTSAGRVPTALGYRFFVDAL
LTVHPMDRVRVEELQGQLLPDQPQRLISSASHLLSQLTQFAGVVVAPRKEAVRIRQIEFIRLSESRILLIIVTAAGDVQN
RILLTKRAYSAVELSNAAQHLNEHFAGLSFDEIRTRVQDELRQLHSDMSELMTATVEAGTEAAAETGNNYVISGETNLLE
VEDLSSNMSRLRELFKLFEQKTGLMQLLDLSNRAQGVQIFIGGESGLAPLDGCSVITSSYEVDGEVVGSVGVIGPTRMAY
DRVIPIVDITARLLSNALSSNH

Sequences:

>Translated_342_residues
MNPLDARSQILLKTLIERYIADGQPVGSRALSRYSGLELSPATVRNVMSDLEEMGFIASPHTSAGRVPTALGYRFFVDAL
LTVHPMDRVRVEELQGQLLPDQPQRLISSASHLLSQLTQFAGVVVAPRKEAVRIRQIEFIRLSESRILLIIVTAAGDVQN
RILLTKRAYSAVELSNAAQHLNEHFAGLSFDEIRTRVQDELRQLHSDMSELMTATVEAGTEAAAETGNNYVISGETNLLE
VEDLSSNMSRLRELFKLFEQKTGLMQLLDLSNRAQGVQIFIGGESGLAPLDGCSVITSSYEVDGEVVGSVGVIGPTRMAY
DRVIPIVDITARLLSNALSSNH
>Mature_342_residues
MNPLDARSQILLKTLIERYIADGQPVGSRALSRYSGLELSPATVRNVMSDLEEMGFIASPHTSAGRVPTALGYRFFVDAL
LTVHPMDRVRVEELQGQLLPDQPQRLISSASHLLSQLTQFAGVVVAPRKEAVRIRQIEFIRLSESRILLIIVTAAGDVQN
RILLTKRAYSAVELSNAAQHLNEHFAGLSFDEIRTRVQDELRQLHSDMSELMTATVEAGTEAAAETGNNYVISGETNLLE
VEDLSSNMSRLRELFKLFEQKTGLMQLLDLSNRAQGVQIFIGGESGLAPLDGCSVITSSYEVDGEVVGSVGVIGPTRMAY
DRVIPIVDITARLLSNALSSNH

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 37471; Mature: 37471

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLDARSQILLKTLIERYIADGQPVGSRALSRYSGLELSPATVRNVMSDLEEMGFIASP
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
HTSAGRVPTALGYRFFVDALLTVHPMDRVRVEELQGQLLPDQPQRLISSASHLLSQLTQF
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AGVVVAPRKEAVRIRQIEFIRLSESRILLIIVTAAGDVQNRILLTKRAYSAVELSNAAQH
HCEEECCCHHHHHHHHEEEEEECCCCEEEEEEECCCCCHHHEEEHHHHHHHHHHHHHHHH
LNEHFAGLSFDEIRTRVQDELRQLHSDMSELMTATVEAGTEAAAETGNNYVISGETNLLE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCEEE
VEDLSSNMSRLRELFKLFEQKTGLMQLLDLSNRAQGVQIFIGGESGLAPLDGCSVITSSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHCCC
EVDGEVVGSVGVIGPTRMAYDRVIPIVDITARLLSNALSSNH
CCCCHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNPLDARSQILLKTLIERYIADGQPVGSRALSRYSGLELSPATVRNVMSDLEEMGFIASP
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCC
HTSAGRVPTALGYRFFVDALLTVHPMDRVRVEELQGQLLPDQPQRLISSASHLLSQLTQF
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
AGVVVAPRKEAVRIRQIEFIRLSESRILLIIVTAAGDVQNRILLTKRAYSAVELSNAAQH
HCEEECCCHHHHHHHHEEEEEECCCCEEEEEEECCCCCHHHEEEHHHHHHHHHHHHHHHH
LNEHFAGLSFDEIRTRVQDELRQLHSDMSELMTATVEAGTEAAAETGNNYVISGETNLLE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCEEE
VEDLSSNMSRLRELFKLFEQKTGLMQLLDLSNRAQGVQIFIGGESGLAPLDGCSVITSSY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHCCC
EVDGEVVGSVGVIGPTRMAYDRVIPIVDITARLLSNALSSNH
CCCCHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA