Click here to switch to the map view.

The map label for this gene is fur [H]

Identifier: 119898869

GI number: 119898869

Start: 2857844

End: 2858281

Strand: Direct

Name: fur [H]

Synonym: azo2578

Alternate gene names: 119898869

Gene position: 2857844-2858281 (Clockwise)

Preceding gene: 119898865

Following gene: 119898872

Centisome position: 65.31

GC content: 60.96

Gene sequence:

>438_bases
ATGTCCGAGAACTCCAAGAACCTCAAGAGCATCGGCCTCAAGGCGACCTATCCGCGCCTCAAGATCCTCGACCTCTTCCA
GACTTCCGACCAGCGCCACCTCACGGCAGAAGACGTCTATCGCCTGCTGATGGGCGAAGGCATGGACATCGGCCTGGCCA
CGGTTTATCGCGTCCTTACCCAGTTCGAGCAGGCCGGCCTGCTGGAGCGGCATTACTTCGAATCCGGCAAGGCGGTTTTC
GAACTCAACCAGGGCGGCCACCACGACCACCTCGTCTGCCTGCAATGTGGCAAGGTCGAAGAGTTCTTCGACCCCGAAAT
CGAAAAGCGCCAGAACGCGATCGCCGAAGCGCGCGGCTTTGCCGTAAAGGAACACGCGCTGTACCTGTACGCCGACTGCC
TGCGCAAGGATTGCCCCAACCGCCACGGCGAGCACTGA

Upstream 100 bases:

>100_bases
ATGCACCGCCGAAAGCGGCGCTGGTTCTCAGTAAAGGGCAAAAAATATAACATAGGGCCGTACCGCGGCAGCGCCTGCAT
TCTCTCCCCACAGGACGAAC

Downstream 100 bases:

>100_bases
GCGCCGCCCGGCGGCGGCGCAGGCCTTACCCCAGCCCCAGCATCTCCGCGGCGTGCTGCCGCGTGGTGGCGGTGATGTTG
ACGCCGCCCAGCATGCGCGC

Product: putative ferric uptake regulation protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSENSKNLKSIGLKATYPRLKILDLFQTSDQRHLTAEDVYRLLMGEGMDIGLATVYRVLTQFEQAGLLERHYFESGKAVF
ELNQGGHHDHLVCLQCGKVEEFFDPEIEKRQNAIAEARGFAVKEHALYLYADCLRKDCPNRHGEH

Sequences:

>Translated_145_residues
MSENSKNLKSIGLKATYPRLKILDLFQTSDQRHLTAEDVYRLLMGEGMDIGLATVYRVLTQFEQAGLLERHYFESGKAVF
ELNQGGHHDHLVCLQCGKVEEFFDPEIEKRQNAIAEARGFAVKEHALYLYADCLRKDCPNRHGEH
>Mature_144_residues
SENSKNLKSIGLKATYPRLKILDLFQTSDQRHLTAEDVYRLLMGEGMDIGLATVYRVLTQFEQAGLLERHYFESGKAVFE
LNQGGHHDHLVCLQCGKVEEFFDPEIEKRQNAIAEARGFAVKEHALYLYADCLRKDCPNRHGEH

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulator for biosynthesis of the siderophore alcaligin E [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=145, Percent_Identity=55.1724137931034, Blast_Score=162, Evalue=7e-42,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16624; Mature: 16493

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSKNLKSIGLKATYPRLKILDLFQTSDQRHLTAEDVYRLLMGEGMDIGLATVYRVLT
CCCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
QFEQAGLLERHYFESGKAVFELNQGGHHDHLVCLQCGKVEEFFDPEIEKRQNAIAEARGF
HHHHCCHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHHCCCHHHHHHHHHHHHHCC
AVKEHALYLYADCLRKDCPNRHGEH
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SENSKNLKSIGLKATYPRLKILDLFQTSDQRHLTAEDVYRLLMGEGMDIGLATVYRVLT
CCCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
QFEQAGLLERHYFESGKAVFELNQGGHHDHLVCLQCGKVEEFFDPEIEKRQNAIAEARGF
HHHHCCHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCCHHHCCCHHHHHHHHHHHHHCC
AVKEHALYLYADCLRKDCPNRHGEH
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA