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The map label for this gene is opcM2 [H]

Identifier: 119898861

GI number: 119898861

Start: 2848984

End: 2850510

Strand: Direct

Name: opcM2 [H]

Synonym: azo2570

Alternate gene names: 119898861

Gene position: 2848984-2850510 (Clockwise)

Preceding gene: 119898860

Following gene: 119898865

Centisome position: 65.1

GC content: 73.54

Gene sequence:

>1527_bases
ATGAACGACAACGCATCAAGACTCACCCGGCGCATCCCGCTGCTGCTCGCCACCCTGCTGACGCTGGCAGGCTGCTCAAT
GGCGCCGGTGTATGAGCGCCCCGAGGTGGCCACCCCGGCCGCCTTCAAGGAAGCCGACCCGGCGCTCGAAGCCGCCGCCG
CGAAGTGGAAGACCGCCGCCCCTGCCGACGACCAGCACCGCGGCGAATGGTGGCGCATCTTCGGCGACGACACGCTCAAC
GCACTCGAAGCCGAGGCGCTCGCCGCCAACCAGGACCTCAAGGCCGCCGTCGCCCGCCTGGCCCAGGCACGCGCGCTGGA
AGGCAGCGCCCGTTCCGAGCGTCTGCCGCAGATCGACGCCAGCTTCGGCCCCACCCGCCAGCGCCCCTCGCCCGCCTCGC
AAGGGCTGGACGAGGACGCCTCGGTGTCGCCCCGCACGCTGTGGCGGGCGCAAGTGGGGATCGGCTACGAAGTGGATCTG
TTCGGCCGCGTCGCTTCCAGCGTGGATGCGGCCGGCGCCGACACCCAGCAGCGCGAGGCGCTGCTGCGCTCGGTGCAGCT
CGCGCTGCAGGCGGATGTGGCCCAGGCCTACTTCCTGTTGCGCGAACTCGACGCCGAGCAGGCACTGTTCCGCGCCACGG
TGGACCTGCGCGGCGAGGCGCTGAAGCTGGTGCAGCGCCGCTTCGAGGCCGGCGACATCGGCGAACTCGACGTGGCCCGT
GCCCGCACCGAACTGGCCAGCGCGCAGTCGGAAGCGCACGGCATCGCCCGCCGCCGCGCCGCCGCCGAGCATGCGCTCGC
CATCCTGCTCGGCAAGCCGCCGGCGGAGTTCAGCTTCGCCGCCCAGCCGCTGGCCCGCATCACGGTGGGCGTGCCGGCCG
GGCTGCCGTCGGCGCTGCTCGAACGCCGGCCCGACATCGCCGCCGCCGAACGCGCGATGGCGGCCGCCAACGCCCGCATC
GGCGTGGCACGCGCCGCCTTCTTCCCGCGCCTGAGCCTGACCGGCGCGCTCGGCTACGAATCCGCCGAACTCGGCGACCT
CTTCCAGTGGTCCAGCCGCACCTTCCTGCTCGGCCCGCTGGTCGGCGGCGTGCTGTCGATGCCGATCTTTGACGGCGGCC
GCCGCCAGGCCGACCTCGACCGCGCCCGCGCGGTGTACGAGGAAGACGTGGCGCGCTACCGCCAGACGGTGCTCGGTGCC
TTCCGCGAGGTGGAGGACGGGCTCGCCAACCTGCGCATCCTCGGCAGGCAGACCCAGGCCCAGGACGAAGCGGTGGCCGC
ATCCGAACGCGCCGCGCGGCTGTCGCAACTGCAGTACCGCGAAGGCGCGACCAGCTATTTCGAAGTGATCGACGCCGACC
GCAGCGTGCTGCAGCAGCGCCGGGTGGCAGTGCAGCTGGATGGCGAACGGGCACGCTCCACGGTGGCACTGATCCGCGCG
CTCGGGGGTGGTTGGGCGACCGCGGCCTCCGCCGAGGCGGCCCCGCCCAACGGCCCGGCCGCCACCCTGGCGGCCAACGC
GCGCTAG

Upstream 100 bases:

>100_bases
CTGCGCAGCCTCGGCAGGGGCAGCAAGCTGCACACCGCCAGTCCCCATGCCGCGCCGATTCCCGCGCCCCATCTTGTGTC
CTGAGCCCGGAGCCGACGAC

Downstream 100 bases:

>100_bases
CTCCGGTGCAGCGCGCGGCGGCGGCCCGCTAGCCGGGCAACGCCACCGCGCGCAACACCGAGGGCGCGATCACACGGTGC
ATCGGCGTGACCGGCAGCAT

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MNDNASRLTRRIPLLLATLLTLAGCSMAPVYERPEVATPAAFKEADPALEAAAAKWKTAAPADDQHRGEWWRIFGDDTLN
ALEAEALAANQDLKAAVARLAQARALEGSARSERLPQIDASFGPTRQRPSPASQGLDEDASVSPRTLWRAQVGIGYEVDL
FGRVASSVDAAGADTQQREALLRSVQLALQADVAQAYFLLRELDAEQALFRATVDLRGEALKLVQRRFEAGDIGELDVAR
ARTELASAQSEAHGIARRRAAAEHALAILLGKPPAEFSFAAQPLARITVGVPAGLPSALLERRPDIAAAERAMAAANARI
GVARAAFFPRLSLTGALGYESAELGDLFQWSSRTFLLGPLVGGVLSMPIFDGGRRQADLDRARAVYEEDVARYRQTVLGA
FREVEDGLANLRILGRQTQAQDEAVAASERAARLSQLQYREGATSYFEVIDADRSVLQQRRVAVQLDGERARSTVALIRA
LGGGWATAASAEAAPPNGPAATLAANAR

Sequences:

>Translated_508_residues
MNDNASRLTRRIPLLLATLLTLAGCSMAPVYERPEVATPAAFKEADPALEAAAAKWKTAAPADDQHRGEWWRIFGDDTLN
ALEAEALAANQDLKAAVARLAQARALEGSARSERLPQIDASFGPTRQRPSPASQGLDEDASVSPRTLWRAQVGIGYEVDL
FGRVASSVDAAGADTQQREALLRSVQLALQADVAQAYFLLRELDAEQALFRATVDLRGEALKLVQRRFEAGDIGELDVAR
ARTELASAQSEAHGIARRRAAAEHALAILLGKPPAEFSFAAQPLARITVGVPAGLPSALLERRPDIAAAERAMAAANARI
GVARAAFFPRLSLTGALGYESAELGDLFQWSSRTFLLGPLVGGVLSMPIFDGGRRQADLDRARAVYEEDVARYRQTVLGA
FREVEDGLANLRILGRQTQAQDEAVAASERAARLSQLQYREGATSYFEVIDADRSVLQQRRVAVQLDGERARSTVALIRA
LGGGWATAASAEAAPPNGPAATLAANAR
>Mature_508_residues
MNDNASRLTRRIPLLLATLLTLAGCSMAPVYERPEVATPAAFKEADPALEAAAAKWKTAAPADDQHRGEWWRIFGDDTLN
ALEAEALAANQDLKAAVARLAQARALEGSARSERLPQIDASFGPTRQRPSPASQGLDEDASVSPRTLWRAQVGIGYEVDL
FGRVASSVDAAGADTQQREALLRSVQLALQADVAQAYFLLRELDAEQALFRATVDLRGEALKLVQRRFEAGDIGELDVAR
ARTELASAQSEAHGIARRRAAAEHALAILLGKPPAEFSFAAQPLARITVGVPAGLPSALLERRPDIAAAERAMAAANARI
GVARAAFFPRLSLTGALGYESAELGDLFQWSSRTFLLGPLVGGVLSMPIFDGGRRQADLDRARAVYEEDVARYRQTVLGA
FREVEDGLANLRILGRQTQAQDEAVAASERAARLSQLQYREGATSYFEVIDADRSVLQQRRVAVQLDGERARSTVALIRA
LGGGWATAASAEAAPPNGPAATLAANAR

Specific function: The outer membrane component of an organic solvent efflux pump. Involved in export of a number of low log POW compounds including hexane (log POW 3.5), toluene (log POW 2.5) and dimethylphthalate (log POW 2.3). The solvent resistance phenotype has been po

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=482, Percent_Identity=32.3651452282158, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI2367348, Length=493, Percent_Identity=26.9776876267748, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 54371; Mature: 54371

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDNASRLTRRIPLLLATLLTLAGCSMAPVYERPEVATPAAFKEADPALEAAAAKWKTAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCC
PADDQHRGEWWRIFGDDTLNALEAEALAANQDLKAAVARLAQARALEGSARSERLPQIDA
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
SFGPTRQRPSPASQGLDEDASVSPRTLWRAQVGIGYEVDLFGRVASSVDAAGADTQQREA
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHH
LLRSVQLALQADVAQAYFLLRELDAEQALFRATVDLRGEALKLVQRRFEAGDIGELDVAR
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHH
ARTELASAQSEAHGIARRRAAAEHALAILLGKPPAEFSFAAQPLARITVGVPAGLPSALL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHCCHHHEEECCCCCCHHHHH
ERRPDIAAAERAMAAANARIGVARAAFFPRLSLTGALGYESAELGDLFQWSSRTFLLGPL
HCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCCEEHHHH
VGGVLSMPIFDGGRRQADLDRARAVYEEDVARYRQTVLGAFREVEDGLANLRILGRQTQA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QDEAVAASERAARLSQLQYREGATSYFEVIDADRSVLQQRRVAVQLDGERARSTVALIRA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHH
LGGGWATAASAEAAPPNGPAATLAANAR
HCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNDNASRLTRRIPLLLATLLTLAGCSMAPVYERPEVATPAAFKEADPALEAAAAKWKTAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHCCCCC
PADDQHRGEWWRIFGDDTLNALEAEALAANQDLKAAVARLAQARALEGSARSERLPQIDA
CCCCCCCCCEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCC
SFGPTRQRPSPASQGLDEDASVSPRTLWRAQVGIGYEVDLFGRVASSVDAAGADTQQREA
CCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCHHHHHH
LLRSVQLALQADVAQAYFLLRELDAEQALFRATVDLRGEALKLVQRRFEAGDIGELDVAR
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHH
ARTELASAQSEAHGIARRRAAAEHALAILLGKPPAEFSFAAQPLARITVGVPAGLPSALL
HHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHCCHHHEEECCCCCCHHHHH
ERRPDIAAAERAMAAANARIGVARAAFFPRLSLTGALGYESAELGDLFQWSSRTFLLGPL
HCCCCHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCCEEHHHH
VGGVLSMPIFDGGRRQADLDRARAVYEEDVARYRQTVLGAFREVEDGLANLRILGRQTQA
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
QDEAVAASERAARLSQLQYREGATSYFEVIDADRSVLQQRRVAVQLDGERARSTVALIRA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHH
LGGGWATAASAEAAPPNGPAATLAANAR
HCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9417051; 9852029 [H]