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The map label for this gene is proA [H]

Identifier: 119898832

GI number: 119898832

Start: 2808905

End: 2809594

Strand: Reverse

Name: proA [H]

Synonym: azo2541

Alternate gene names: 119898832

Gene position: 2809594-2808905 (Counterclockwise)

Preceding gene: 119898833

Following gene: 119898831

Centisome position: 64.2

GC content: 70.58

Gene sequence:

>690_bases
ATGTCCGTGAACAACCTCGGCATCGTCAAGCGCAACATCGAGCGCACCGACAAGGCCACCGTCGAGCGCCTCTCCAGGTT
CGGCGTCGCCACCATCCACGAGGCGATGGGCCGCGCCGGGCTGATGAAGCCCTACATCCGCCCGATCTACCAGGGCGCCT
ACGTGTGCGGCACCGCGGTCACCATCCTCGCCCAGCCGGGCGACAACTGGATGCTGCACGTCGCCGCCGAGCAGCTGCAG
GATGGCGACGTGGCCGTGGTGGCCTGCACCGCCGACAGTACCGACGGCATGTTCGGCGATCTGCTGGCGACGTCCTACCG
CGCCCGCGGCGCCCGCGGCCTGATCTCCGACGCCGGCGTGCGCGACGTCAAGGACCTCACCGCGATGCAGTTCCCGGTGT
TCTCGCGCGCCATCAGCGCCAAGGGCTGCGTGCGTGCCACGCTGGGTTCGGTGAATGTGCCGGTGGTGTGCGCCGGCGCG
GTGGTCAACCCGGGTGACGTGGTGGTGGCGGACGACGACGGCGTGGTGGTGGTGCCGCGTGAGGTCGCCGCCAAGGTGGC
CGACGCCGCCGAAGCGCGCGAAGCCAACGAGGCCGCCAAGCGCGCCCGCTTCGCCGCCGGCGAACTGGGCCTGGACATGT
ACTCGCTGCGCGAGCCGCTGGCCAAGGCCGGCCTCAAGTACATCGACTGA

Upstream 100 bases:

>100_bases
AGACCGCTACAAGATCTACGAAGGCAATGCCCGCCGCGTCTATCCGCGCCTGGATGCCGCCCTCAAGGCCAAGGGCCTGT
AAGCCTCAGGAGAACACACC

Downstream 100 bases:

>100_bases
TCATGGCCGCGCCCGCCAATCCCATGCTGTGGCGCATCGGCCTCGTCGGTTACGGCGAGGTCGGCCGCATCCTCGCGGAG
GATCTGCGCGATCAGGGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSVNNLGIVKRNIERTDKATVERLSRFGVATIHEAMGRAGLMKPYIRPIYQGAYVCGTAVTILAQPGDNWMLHVAAEQLQ
DGDVAVVACTADSTDGMFGDLLATSYRARGARGLISDAGVRDVKDLTAMQFPVFSRAISAKGCVRATLGSVNVPVVCAGA
VVNPGDVVVADDDGVVVVPREVAAKVADAAEAREANEAAKRARFAAGELGLDMYSLREPLAKAGLKYID

Sequences:

>Translated_229_residues
MSVNNLGIVKRNIERTDKATVERLSRFGVATIHEAMGRAGLMKPYIRPIYQGAYVCGTAVTILAQPGDNWMLHVAAEQLQ
DGDVAVVACTADSTDGMFGDLLATSYRARGARGLISDAGVRDVKDLTAMQFPVFSRAISAKGCVRATLGSVNVPVVCAGA
VVNPGDVVVADDDGVVVVPREVAAKVADAAEAREANEAAKRARFAAGELGLDMYSLREPLAKAGLKYID
>Mature_228_residues
SVNNLGIVKRNIERTDKATVERLSRFGVATIHEAMGRAGLMKPYIRPIYQGAYVCGTAVTILAQPGDNWMLHVAAEQLQD
GDVAVVACTADSTDGMFGDLLATSYRARGARGLISDAGVRDVKDLTAMQFPVFSRAISAKGCVRATLGSVNVPVVCAGAV
VNPGDVVVADDDGVVVVPREVAAKVADAAEAREANEAAKRARFAAGELGLDMYSLREPLAKAGLKYID

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 24124; Mature: 23993

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNNLGIVKRNIERTDKATVERLSRFGVATIHEAMGRAGLMKPYIRPIYQGAYVCGTAV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCEE
TILAQPGDNWMLHVAAEQLQDGDVAVVACTADSTDGMFGDLLATSYRARGARGLISDAGV
EEEECCCCCEEEEEEHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
RDVKDLTAMQFPVFSRAISAKGCVRATLGSVNVPVVCAGAVVNPGDVVVADDDGVVVVPR
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEECCEECCCCEEEECCCCEEEECH
EVAAKVADAAEAREANEAAKRARFAAGELGLDMYSLREPLAKAGLKYID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVNNLGIVKRNIERTDKATVERLSRFGVATIHEAMGRAGLMKPYIRPIYQGAYVCGTAV
CCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCEE
TILAQPGDNWMLHVAAEQLQDGDVAVVACTADSTDGMFGDLLATSYRARGARGLISDAGV
EEEECCCCCEEEEEEHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
RDVKDLTAMQFPVFSRAISAKGCVRATLGSVNVPVVCAGAVVNPGDVVVADDDGVVVVPR
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEEECCEECCCCEEEECCCCEEEECH
EVAAKVADAAEAREANEAAKRARFAAGELGLDMYSLREPLAKAGLKYID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]