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The map label for this gene is nahR2 [H]

Identifier: 119898809

GI number: 119898809

Start: 2784640

End: 2785581

Strand: Direct

Name: nahR2 [H]

Synonym: azo2518

Alternate gene names: 119898809

Gene position: 2784640-2785581 (Clockwise)

Preceding gene: 119898797

Following gene: 119898815

Centisome position: 63.63

GC content: 69.32

Gene sequence:

>942_bases
ATGGAACTGCGCGACATCGACCTCAACCTGCTGGTGGTCTTCAACCAGTTGCTGACCGAGCGCCGGGTATCCGGCGTGGC
CGACACCCTAGGCCTCACCCAACCGGCGGTGAGCAATGCGCTCAAGCGCCTGCGCGCAGTGCTCGGCGACGAACTCTTCG
TGCGCACCGGCCGCGGCATGGAACCGACGCCGCTCGCGCTGCAGCTCGCCGAACCGGTGGCCTACGCGCTCGGCACCCTG
CACGGCGCGCTCAACCAGCAGGCCCGCTTCGACCCCGCCACCAGCCAGCGCAGCTTCACGCTGGCGGTCACCGACATCGG
CGAGATCTACTTCCTGCCGGTGCTGATGGACGCGCTCGCCGCGATCGCGCCCGGCGTGCGCATCAGCACCGTGCGCAACA
GCGGCGCCAAGCTGCGCGACGAGATGGAGGCCGGCACGGTGGATCTCGCCATCGGCCTGCTGCCCAACCTGCAGGCGGGC
TTCTACCAGCGCCGGCTGTTCCACCAGCGCTACGTCTGCATGTTCCGCAAGCAGCATCCGGCGGTGACGCTGCCACTGAC
GCTGGAGAACTTCTCGGCGCTGGACCACGTGGTGGTGATCTCCGGCGGCACCGGCCACAGCCAGGTGGACGCGATGCTGG
AGCGCGCTGGCATCCAGCGCCGGGTGCGGCTGACGGTGCCGCACTTCATCGCGGTCGGCCACATCCTGCAGAGCACCGAC
ATGATCGCCACCGTGCCGGAGCGCTTCGCCGCCCGCTGCGTGGAACCCTTCGGCCTGGTGTCGGTGCCGCATCCGGCCAA
GCTGCCGGAGATCGCAATCAACCTCTTCTGGCACGGCCGCTACCACCGCGACCCGGCCAACCGCTGGCTGCGGCAGCTGG
TGTTCGAGCGGTTTGGGGAATCGACCGCGCAGGAACAGGCGGTGGAGCCACCGGCAAGCTGA

Upstream 100 bases:

>100_bases
GTGATGAAACGTTCGATGGGCGCCATCATGGATCGAGGCGTGTTATACATCCATAAAATTGATTGAATACGTCACATCAC
CAACCTGAATACTGCGAAAC

Downstream 100 bases:

>100_bases
GCCTCTCGCCGGAGCCACGCTTCCGCCTGTGCCGCCTGCGCAAACAAAAAGGGCGGCACCCGCAGGCACCGCCCTTTTTT
TCCCATCCTCCTGCGCGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MELRDIDLNLLVVFNQLLTERRVSGVADTLGLTQPAVSNALKRLRAVLGDELFVRTGRGMEPTPLALQLAEPVAYALGTL
HGALNQQARFDPATSQRSFTLAVTDIGEIYFLPVLMDALAAIAPGVRISTVRNSGAKLRDEMEAGTVDLAIGLLPNLQAG
FYQRRLFHQRYVCMFRKQHPAVTLPLTLENFSALDHVVVISGGTGHSQVDAMLERAGIQRRVRLTVPHFIAVGHILQSTD
MIATVPERFAARCVEPFGLVSVPHPAKLPEIAINLFWHGRYHRDPANRWLRQLVFERFGESTAQEQAVEPPAS

Sequences:

>Translated_313_residues
MELRDIDLNLLVVFNQLLTERRVSGVADTLGLTQPAVSNALKRLRAVLGDELFVRTGRGMEPTPLALQLAEPVAYALGTL
HGALNQQARFDPATSQRSFTLAVTDIGEIYFLPVLMDALAAIAPGVRISTVRNSGAKLRDEMEAGTVDLAIGLLPNLQAG
FYQRRLFHQRYVCMFRKQHPAVTLPLTLENFSALDHVVVISGGTGHSQVDAMLERAGIQRRVRLTVPHFIAVGHILQSTD
MIATVPERFAARCVEPFGLVSVPHPAKLPEIAINLFWHGRYHRDPANRWLRQLVFERFGESTAQEQAVEPPAS
>Mature_313_residues
MELRDIDLNLLVVFNQLLTERRVSGVADTLGLTQPAVSNALKRLRAVLGDELFVRTGRGMEPTPLALQLAEPVAYALGTL
HGALNQQARFDPATSQRSFTLAVTDIGEIYFLPVLMDALAAIAPGVRISTVRNSGAKLRDEMEAGTVDLAIGLLPNLQAG
FYQRRLFHQRYVCMFRKQHPAVTLPLTLENFSALDHVVVISGGTGHSQVDAMLERAGIQRRVRLTVPHFIAVGHILQSTD
MIATVPERFAARCVEPFGLVSVPHPAKLPEIAINLFWHGRYHRDPANRWLRQLVFERFGESTAQEQAVEPPAS

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=294, Percent_Identity=28.5714285714286, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87081766, Length=284, Percent_Identity=26.056338028169, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790147, Length=296, Percent_Identity=25.3378378378378, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786820, Length=300, Percent_Identity=23, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34593; Mature: 34593

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRDIDLNLLVVFNQLLTERRVSGVADTLGLTQPAVSNALKRLRAVLGDELFVRTGRGM
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCC
EPTPLALQLAEPVAYALGTLHGALNQQARFDPATSQRSFTLAVTDIGEIYFLPVLMDALA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
AIAPGVRISTVRNSGAKLRDEMEAGTVDLAIGLLPNLQAGFYQRRLFHQRYVCMFRKQHP
HHCCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
AVTLPLTLENFSALDHVVVISGGTGHSQVDAMLERAGIQRRVRLTVPHFIAVGHILQSTD
CEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHCC
MIATVPERFAARCVEPFGLVSVPHPAKLPEIAINLFWHGRYHRDPANRWLRQLVFERFGE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCC
STAQEQAVEPPAS
HHHHHHCCCCCCC
>Mature Secondary Structure
MELRDIDLNLLVVFNQLLTERRVSGVADTLGLTQPAVSNALKRLRAVLGDELFVRTGRGM
CCCEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHEEECCCCC
EPTPLALQLAEPVAYALGTLHGALNQQARFDPATSQRSFTLAVTDIGEIYFLPVLMDALA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHH
AIAPGVRISTVRNSGAKLRDEMEAGTVDLAIGLLPNLQAGFYQRRLFHQRYVCMFRKQHP
HHCCCCEEEEECCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCC
AVTLPLTLENFSALDHVVVISGGTGHSQVDAMLERAGIQRRVRLTVPHFIAVGHILQSTD
CEEEEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHCCHHEEEECCHHHHHHHHHHHHCC
MIATVPERFAARCVEPFGLVSVPHPAKLPEIAINLFWHGRYHRDPANRWLRQLVFERFGE
HHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCC
STAQEQAVEPPAS
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]