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The map label for this gene is etfA3 [H]

Identifier: 119898782

GI number: 119898782

Start: 2754465

End: 2755391

Strand: Reverse

Name: etfA3 [H]

Synonym: azo2491

Alternate gene names: 119898782

Gene position: 2755391-2754465 (Counterclockwise)

Preceding gene: 119898783

Following gene: 119898781

Centisome position: 62.97

GC content: 69.15

Gene sequence:

>927_bases
ATGGCCATTCTTGTCCTTGCCGAACACGACAACCACACCATCAAGGCCGCCACGCTCAACACGGTGACGGCCGCCGCCAA
GATCGGCGGTGACATCCATGTTCTCGTCGCCGGCAGCAACTGCGGCGCCGCCGCCGAAGCCGCGGCCAAGGTGGCCGGCG
TTGCCAAGGTGCTGGTGGCCGACGCCCCGCATCTGGACGCCCAGCTCGCCGAGAACGTGAGCGTGCTGCTGCAGACGCTC
GCGCCGGCCTACAGCCACGTGCTCGCGCCGTCGACTTCCGCCGGCAAGAACACGCTGCCGCGCATGGCCGCGCTGCTCGA
CGTCGCGCAGATCAGCGACATCGTCGGTGTGGAAGCCGCCGACACCTTCGTGCGCCCGATCTACGCCGGGAACGCGCTCG
CGACGGTGAAGAGCGCAGACGCGGTCAAGGTCATCACCGTGCGCACCACCGCGTTCGAAGCAGCAGGCGAGGGCGGTAGT
GCCGCGATCGAAGCGGTCGCCACCGGCGCGGATGCCGGCCAGTCCAACCTCGTCGGCCGCGAGATCACCAAGAGCGCGCG
CCCCGAACTCGGTGCCGCCAAGATCATCGTCTCCGGCGGTCGCGGCCTGGGCAGCGGCGAGAACTACACCACGCTGCTCG
AACCGCTCGCCGACAAGCTGGGCGCGGCGCTCGGCGCGAGCCGCGCGGCGGTCGATGCGGGCTACGTGCCCAACGACTAC
CAGGTCGGCCAGACCGGCAAGATCGTCGCGCCGCAGCTCTACATCGCGGTCGGCATCTCGGGTGCCATCCAGCACCTGGC
CGGCATGAAGGATTCCAAGGTGATCGTGGCGATCAACAAGGACCCCGAAGCGCCGATCTTCCAGGTGGCCGACTACGGTC
TGGTGGGTGACCTGTTCGAGGTGGTGCCGGCGCTGACCGCGGCCTGA

Upstream 100 bases:

>100_bases
CGCTGAAAGTGACCGAGCCGCCCAAGCGCAGCGCCGGGGTGCGGGTGGCCGATGTGGCCCAGCTGGTCGACAAACTGAAG
AACGAAGCGAAGGTGCTCTG

Downstream 100 bases:

>100_bases
ACGGGGCGCGTCAGGACGACGGGGCGGGAGCCGCCGCAGCGGGTTCTCCCCGGACTCCGGCAACCCGTCCGCAGCGGCGC
GTTGCACGGCGCACTGCCGC

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAILVLAEHDNHTIKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVADAPHLDAQLAENVSVLLQTL
APAYSHVLAPSTSAGKNTLPRMAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGS
AAIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAA

Sequences:

>Translated_308_residues
MAILVLAEHDNHTIKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVADAPHLDAQLAENVSVLLQTL
APAYSHVLAPSTSAGKNTLPRMAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGS
AAIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAA
>Mature_307_residues
AILVLAEHDNHTIKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVADAPHLDAQLAENVSVLLQTLA
PAYSHVLAPSTSAGKNTLPRMAALLDVAQISDIVGVEAADTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSA
AIEAVATGADAGQSNLVGREITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDYQ
VGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFEVVPALTAA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=306, Percent_Identity=59.8039215686275, Blast_Score=348, Evalue=5e-96,
Organism=Homo sapiens, GI189181759, Length=267, Percent_Identity=61.4232209737828, Blast_Score=305, Evalue=3e-83,
Organism=Escherichia coli, GI1786226, Length=238, Percent_Identity=38.2352941176471, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787990, Length=253, Percent_Identity=33.596837944664, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082157, Length=230, Percent_Identity=32.1739130434783, Blast_Score=84, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17506929, Length=309, Percent_Identity=57.9288025889968, Blast_Score=332, Evalue=2e-91,
Organism=Saccharomyces cerevisiae, GI6325261, Length=289, Percent_Identity=45.3287197231834, Blast_Score=249, Evalue=4e-67,
Organism=Drosophila melanogaster, GI17136898, Length=307, Percent_Identity=63.5179153094463, Blast_Score=363, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24652801, Length=307, Percent_Identity=63.5179153094463, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 30841; Mature: 30710

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILVLAEHDNHTIKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVA
CEEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
DAPHLDAQLAENVSVLLQTLAPAYSHVLAPSTSAGKNTLPRMAALLDVAQISDIVGVEAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
DTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSAAIEAVATGADAGQSNLVGR
HHHHHHHCCCCEEEEEECCCCEEEEEEEEEEHHCCCCCCCHHHHHHHCCCCCCCCCCCHH
EITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDY
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFE
EECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHH
VVPALTAA
HHHHHHCC
>Mature Secondary Structure 
AILVLAEHDNHTIKAATLNTVTAAAKIGGDIHVLVAGSNCGAAAEAAAKVAGVAKVLVA
EEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHC
DAPHLDAQLAENVSVLLQTLAPAYSHVLAPSTSAGKNTLPRMAALLDVAQISDIVGVEAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHH
DTFVRPIYAGNALATVKSADAVKVITVRTTAFEAAGEGGSAAIEAVATGADAGQSNLVGR
HHHHHHHCCCCEEEEEECCCCEEEEEEEEEEHHCCCCCCCHHHHHHHCCCCCCCCCCCHH
EITKSARPELGAAKIIVSGGRGLGSGENYTTLLEPLADKLGAALGASRAAVDAGYVPNDY
HHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLFE
EECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHH
VVPALTAA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]