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The map label for this gene is poxR [H]

Identifier: 119898737

GI number: 119898737

Start: 2698080

End: 2699780

Strand: Direct

Name: poxR [H]

Synonym: azo2446

Alternate gene names: 119898737

Gene position: 2698080-2699780 (Clockwise)

Preceding gene: 119898728

Following gene: 119898739

Centisome position: 61.66

GC content: 68.84

Gene sequence:

>1701_bases
GTGAAGGGAATCCGCTACCCGGAGAACGCCGACCTGCGGCAGTTGCTCCGCTTTTCCGACAAGGACGGGCTGATCTGGCT
GGGCGAGCACCGCATGGTGCTGCTGCACAGCGCCGCTCTGTCCGAACTGCGCAAGGAGCTGATCGACTCGGTCGGCGCCG
AGCAGGCGCGCCGCATCCTCACCCGCATGGGTTTCGCCTCCGGCCTGCGCGATGCCGAACTCGCGCGCAAGATCCGCGGT
GCCGGCTCGCTGGTCGACGCCTTCGTGGTCGGCCCCCAGCTGCACATGCTGGAAGGCTGCGTGGAGGTCGAGCCGGTGAA
GCTGGACATCGACGGCGACGCCGGCAAGTTCTACGGCGAATTCATCTGGCGCCAGTCGTGGGAGGCCGAAGTCCACGTGC
AGCAGTTCGGCGAGGTCGACCACCCGGTGTGCTGGATGATGATCGGCTACGCCTCGGGCTATACCTCCGCCTTCATGGGC
CGCTTCATCCTGTTCCGCGAGGTGGAATGCGCGGCGATGGGCAGCGGCCACTGCCGCATCGTCGGCAAGCCCGCCGAAGA
GTGGCCGGACGCGCATGAACTCACGCCCTACTTCGAGGCCGACTCCATCGTCGGCCGCCTGCTGGAACTGCGCGAGGAAG
TCGAAGCGATGCGGCAGAGCATCGCCTGCCCGCGCCGCATCCCCAACCTCATCGGCGCCTCCGGCGGCTTTCGCAGCGCC
TACGAGCTGGTCACCAAGGCGGCGGCCACCAACGTCAGCGTGCTGCTGCTGGGAGAAACCGGGGTCGGCAAGGAACGCTT
CGCACGCGCGCTGCACGAGTTGAGCCCGCGCAAAGACGCGCCCTTCATCGCGGTGAACTGCGCCGCACTGCCCGACGAGC
TGATCGAATCCGAACTCTTCGGCGTCGAACGCGGCGCCTTCACCGGCGCCCACGCCTCGCGCGCCGGCAAGTTCGAGCGC
GCCGACGGCGGCACGCTGTTTCTCGACGAGGTCGGCGAACTGCCGCTGCCCGCGCAGGCCAAGCTGCTGCGCGTGCTGCA
GGAAGGCGAGATCGAGCGCCTCGGCGACGAGCGCATCCGCAAGATCAATGTGCGCCTGGTCGCGGCCACCAACGTGGACC
TGCAAGACGCGGTGGCCGCCGGCCGCTTCCGCCGCGACCTCTATTACCGGCTCAACGTCTATCCGGTGACGATTCCGCCG
CTGCGCGAGCGCGCCTCCGACATCCCGCCGCTGGTCGAGGCGATGACCGCGCGCTTCTGTTCGCTGCACGCCAAGCGCGT
TGCCGGCATCACCGACAAGGCGATGCTGGCGCTGAAGAGCCACCGCTGGCCGGGCAATGTGCGCGAGCTGGAAAACGTCA
TCGAGCGCGGCGTCATCCTCGCGCCGCAGAACGGCTGGGTGGAGGTCGAACACCTCTTCGTCGGCGCCATCCCCACGCCC
GCCAGCCACGCCTGCATCGACAAGAGCGGCAAGCTGGGCGAGCAGACGAGCGGCAGCGGTGGCCGCAACCTCACCGACGC
GGTACTCGACGCCGGCATCTCGCTGGAGGCGCTGGAGCAGGACATCCTGCAGCGCGCGGTGCAGCGCGCCAACGGCAACC
TCGCCGCCGCCGCGCGCATGCTCGGCATGACCCGGCCGCAGCTCAACTACCGGCTGAAGAAGCAGTCCGCGCAGAGCGGG
GATTCGGCGGTCGTGGACTAA

Upstream 100 bases:

>100_bases
TATCGTTACGGCTGACCACAGGACGGACGGGCCCCGATGCCCGCCGCCACGCCCGCAGAGGCGAAGCCGGACCGCGCGCG
GACCGGCGCAAGGAGGAGAC

Downstream 100 bases:

>100_bases
CGCTGCCGGTTGGCGTCGCGGAACGCGGACGGCGACATGCCCTGCCGGCGCGCGAAGAAGCGCGAGAAATACGCGGGATC
GCGGAAGCCGAGCGAATAGC

Product: positive regulator of phenol-degratives genes

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 566; Mature: 566

Protein sequence:

>566_residues
MKGIRYPENADLRQLLRFSDKDGLIWLGEHRMVLLHSAALSELRKELIDSVGAEQARRILTRMGFASGLRDAELARKIRG
AGSLVDAFVVGPQLHMLEGCVEVEPVKLDIDGDAGKFYGEFIWRQSWEAEVHVQQFGEVDHPVCWMMIGYASGYTSAFMG
RFILFREVECAAMGSGHCRIVGKPAEEWPDAHELTPYFEADSIVGRLLELREEVEAMRQSIACPRRIPNLIGASGGFRSA
YELVTKAAATNVSVLLLGETGVGKERFARALHELSPRKDAPFIAVNCAALPDELIESELFGVERGAFTGAHASRAGKFER
ADGGTLFLDEVGELPLPAQAKLLRVLQEGEIERLGDERIRKINVRLVAATNVDLQDAVAAGRFRRDLYYRLNVYPVTIPP
LRERASDIPPLVEAMTARFCSLHAKRVAGITDKAMLALKSHRWPGNVRELENVIERGVILAPQNGWVEVEHLFVGAIPTP
ASHACIDKSGKLGEQTSGSGGRNLTDAVLDAGISLEALEQDILQRAVQRANGNLAAAARMLGMTRPQLNYRLKKQSAQSG
DSAVVD

Sequences:

>Translated_566_residues
MKGIRYPENADLRQLLRFSDKDGLIWLGEHRMVLLHSAALSELRKELIDSVGAEQARRILTRMGFASGLRDAELARKIRG
AGSLVDAFVVGPQLHMLEGCVEVEPVKLDIDGDAGKFYGEFIWRQSWEAEVHVQQFGEVDHPVCWMMIGYASGYTSAFMG
RFILFREVECAAMGSGHCRIVGKPAEEWPDAHELTPYFEADSIVGRLLELREEVEAMRQSIACPRRIPNLIGASGGFRSA
YELVTKAAATNVSVLLLGETGVGKERFARALHELSPRKDAPFIAVNCAALPDELIESELFGVERGAFTGAHASRAGKFER
ADGGTLFLDEVGELPLPAQAKLLRVLQEGEIERLGDERIRKINVRLVAATNVDLQDAVAAGRFRRDLYYRLNVYPVTIPP
LRERASDIPPLVEAMTARFCSLHAKRVAGITDKAMLALKSHRWPGNVRELENVIERGVILAPQNGWVEVEHLFVGAIPTP
ASHACIDKSGKLGEQTSGSGGRNLTDAVLDAGISLEALEQDILQRAVQRANGNLAAAARMLGMTRPQLNYRLKKQSAQSG
DSAVVD
>Mature_566_residues
MKGIRYPENADLRQLLRFSDKDGLIWLGEHRMVLLHSAALSELRKELIDSVGAEQARRILTRMGFASGLRDAELARKIRG
AGSLVDAFVVGPQLHMLEGCVEVEPVKLDIDGDAGKFYGEFIWRQSWEAEVHVQQFGEVDHPVCWMMIGYASGYTSAFMG
RFILFREVECAAMGSGHCRIVGKPAEEWPDAHELTPYFEADSIVGRLLELREEVEAMRQSIACPRRIPNLIGASGGFRSA
YELVTKAAATNVSVLLLGETGVGKERFARALHELSPRKDAPFIAVNCAALPDELIESELFGVERGAFTGAHASRAGKFER
ADGGTLFLDEVGELPLPAQAKLLRVLQEGEIERLGDERIRKINVRLVAATNVDLQDAVAAGRFRRDLYYRLNVYPVTIPP
LRERASDIPPLVEAMTARFCSLHAKRVAGITDKAMLALKSHRWPGNVRELENVIERGVILAPQNGWVEVEHLFVGAIPTP
ASHACIDKSGKLGEQTSGSGGRNLTDAVLDAGISLEALEQDILQRAVQRANGNLAAAARMLGMTRPQLNYRLKKQSAQSG
DSAVVD

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=366, Percent_Identity=40.7103825136612, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI87082117, Length=256, Percent_Identity=50, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1789087, Length=235, Percent_Identity=53.6170212765957, Blast_Score=248, Evalue=9e-67,
Organism=Escherichia coli, GI87082152, Length=339, Percent_Identity=42.4778761061947, Blast_Score=235, Evalue=5e-63,
Organism=Escherichia coli, GI1790437, Length=326, Percent_Identity=40.7975460122699, Blast_Score=234, Evalue=9e-63,
Organism=Escherichia coli, GI1788905, Length=317, Percent_Identity=42.2712933753943, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1789233, Length=334, Percent_Identity=39.8203592814371, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1790299, Length=336, Percent_Identity=40.7738095238095, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI87081872, Length=331, Percent_Identity=41.9939577039275, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1786524, Length=354, Percent_Identity=37.0056497175141, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1787583, Length=275, Percent_Identity=36.7272727272727, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI87081858, Length=319, Percent_Identity=33.5423197492163, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1789828, Length=271, Percent_Identity=36.5313653136531, Blast_Score=140, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 62174; Mature: 62174

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIRYPENADLRQLLRFSDKDGLIWLGEHRMVLLHSAALSELRKELIDSVGAEQARRIL
CCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHH
TRMGFASGLRDAELARKIRGAGSLVDAFVVGPQLHMLEGCVEVEPVKLDIDGDAGKFYGE
HHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCEEEEEEEEECCCCHHHHHH
FIWRQSWEAEVHVQQFGEVDHPVCWMMIGYASGYTSAFMGRFILFREVECAAMGSGHCRI
HHHHCCCCCEEHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
VGKPAEEWPDAHELTPYFEADSIVGRLLELREEVEAMRQSIACPRRIPNLIGASGGFRSA
ECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
YELVTKAAATNVSVLLLGETGVGKERFARALHELSPRKDAPFIAVNCAALPDELIESELF
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECHHCCHHHHHHHHH
GVERGAFTGAHASRAGKFERADGGTLFLDEVGELPLPAQAKLLRVLQEGEIERLGDERIR
CCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHE
KINVRLVAATNVDLQDAVAAGRFRRDLYYRLNVYPVTIPPLRERASDIPPLVEAMTARFC
EEEEEEEEEECCCHHHHHHHHHHHHCEEEEEEEEEEECCCHHHHHCCCCHHHHHHHHHHH
SLHAKRVAGITDKAMLALKSHRWPGNVRELENVIERGVILAPQNGWVEVEHLFVGAIPTP
HHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCCEEEEEEEEECCCCC
ASHACIDKSGKLGEQTSGSGGRNLTDAVLDAGISLEALEQDILQRAVQRANGNLAAAARM
CCCHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LGMTRPQLNYRLKKQSAQSGDSAVVD
HHCCCCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKGIRYPENADLRQLLRFSDKDGLIWLGEHRMVLLHSAALSELRKELIDSVGAEQARRIL
CCCCCCCCCCCHHHHHHCCCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHCCHHHHHHHH
TRMGFASGLRDAELARKIRGAGSLVDAFVVGPQLHMLEGCVEVEPVKLDIDGDAGKFYGE
HHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCEEEEEEEEECCCCHHHHHH
FIWRQSWEAEVHVQQFGEVDHPVCWMMIGYASGYTSAFMGRFILFREVECAAMGSGHCRI
HHHHCCCCCEEHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEE
VGKPAEEWPDAHELTPYFEADSIVGRLLELREEVEAMRQSIACPRRIPNLIGASGGFRSA
ECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
YELVTKAAATNVSVLLLGETGVGKERFARALHELSPRKDAPFIAVNCAALPDELIESELF
HHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCEEEEECHHCCHHHHHHHHH
GVERGAFTGAHASRAGKFERADGGTLFLDEVGELPLPAQAKLLRVLQEGEIERLGDERIR
CCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHE
KINVRLVAATNVDLQDAVAAGRFRRDLYYRLNVYPVTIPPLRERASDIPPLVEAMTARFC
EEEEEEEEEECCCHHHHHHHHHHHHCEEEEEEEEEEECCCHHHHHCCCCHHHHHHHHHHH
SLHAKRVAGITDKAMLALKSHRWPGNVRELENVIERGVILAPQNGWVEVEHLFVGAIPTP
HHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCEEEECCCCCEEEEEEEEECCCCC
ASHACIDKSGKLGEQTSGSGGRNLTDAVLDAGISLEALEQDILQRAVQRANGNLAAAARM
CCCHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
LGMTRPQLNYRLKKQSAQSGDSAVVD
HHCCCCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]