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The map label for this gene is dctM4 [H]

Identifier: 119898717

GI number: 119898717

Start: 2679537

End: 2680814

Strand: Direct

Name: dctM4 [H]

Synonym: azo2426

Alternate gene names: 119898717

Gene position: 2679537-2680814 (Clockwise)

Preceding gene: 119898716

Following gene: 119898728

Centisome position: 61.23

GC content: 66.74

Gene sequence:

>1278_bases
ATGATCACGCTGATCGTCTTCTTCGCGCTGCTGTTCTGCGGCTTCCCGATCTTCGGCGCCATTCTCGCCGGCGCGGTGGT
GTTCATGGCCACCAACGACCTCGCCGTGCTCTACGACTCGATCCCGATCCAGTTCTACGGCGCGCTCGAAATCAACGGCC
TGCTCGCGATTCCGCTCTTCATGCTGGTGGGCGAGATCATGAACCAGGGCGGTCTCACCCAGCGCCTGATCGCGGTGGCC
GAGGTGCTGGTCGGCCGCTTCAAGGGCGGGCTGGCCTACGCCAACCTGATCACCAATGCGATGGCCGCGTCCATCCTCGG
CTCGGCCGTTGCGCAGATCGGCGTGATGAGCAAGGTGATGATTCCCGAGATGGAGAAGAAGGGCTACGACAAGGCCTTCT
CCGGCGCGGTCACCGTGTCCGCGGGGCTGCTCGGGCCGATCATTCCGCCGTCGATGCTGATGATCATCTACGGTGTCGTC
GCGGTGCAGCCGATCGCGCCGCTGTTCATCGCCGGCATCGTGCCCGGCCTGCTCATCGTCGCGGTGCTGGCCGGCGTGAT
CCTGCTGTACGGCATGTTCGGCTCCCATCTGCCGGAAGGGTCCCCCACCCCGCTGCGCGACAGCTGGGGCACGCTCGTCG
GCGGCATCGCGCCCGGCCTGATTCCCGCGGTGGTCATCGTCGGCATCATGAGCGGCGCGATGACGCCGACCGAGTCGGGC
GCGGTGGCCTCGCTGATCGCGCTGATCCTCGGCTTCCTCTACCGCGAGCTGAAGCTCGCCGACCTGCCCGGCATCCTGCG
CAGCGTCGCGGTGAACACCGCCACCATCACCGGGCTGATCGCAGCCGCCTCGGTGTTCAGCTGGGTGCTCGCCTTCCAGG
GCGTGCCCGACCAACTGGTGGAACTGATCGCCGGCGTGACCGATTCGCCCGTGGTGTTCCTGCTGCTGGTGACGCTGCTG
ATGCTGGTGCTCGGGATGTTCCTGGAGAGCATCAGCGTGCTGATTGTGGTGGTGCCGATCCTGATGCCGGTGGTCAATGC
GCTCGGCATCAACCCGATCCAGTTCGGGGTGGTATGCACCGTCGCCACGGTGATCGGCATCGTCACGCCGCCGGTCGGCC
CCGGCCTCTATATCGCCATGGTTCAGGCCCACATGCCGATGGGGCCGCTGTTCCGCGCGACGGTGCCTTTCCTCGCCGCG
GTGCTGGCGGTGGTGGTTGCGATCTGCGTCTTCCCGGCGCTGTCCACCTGGCTGCCGGCGCTCTCCGCCGGCAAATGA

Upstream 100 bases:

>100_bases
GGTACAACTATTCGCTGCTGCCCGGCGCGATGCTGGCGATGGCCTTCCACCAGTTCGCCGCGGTACTGCGCCAGGTGCGC
GCGCTGGCCGGAGCGCGCGC

Downstream 100 bases:

>100_bases
GCCTGACGGCGCCGGCTCAACGGCCGGCGCCGGGATTCAACCAGCCGCGCAGCCAGCGGGTCAGGCGCGGCATCACCACC
CAGGTCATCGTCGCCACGAT

Product: putative TRAP-type C4-dicarboxylate transport system large permease

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MITLIVFFALLFCGFPIFGAILAGAVVFMATNDLAVLYDSIPIQFYGALEINGLLAIPLFMLVGEIMNQGGLTQRLIAVA
EVLVGRFKGGLAYANLITNAMAASILGSAVAQIGVMSKVMIPEMEKKGYDKAFSGAVTVSAGLLGPIIPPSMLMIIYGVV
AVQPIAPLFIAGIVPGLLIVAVLAGVILLYGMFGSHLPEGSPTPLRDSWGTLVGGIAPGLIPAVVIVGIMSGAMTPTESG
AVASLIALILGFLYRELKLADLPGILRSVAVNTATITGLIAAASVFSWVLAFQGVPDQLVELIAGVTDSPVVFLLLVTLL
MLVLGMFLESISVLIVVVPILMPVVNALGINPIQFGVVCTVATVIGIVTPPVGPGLYIAMVQAHMPMGPLFRATVPFLAA
VLAVVVAICVFPALSTWLPALSAGK

Sequences:

>Translated_425_residues
MITLIVFFALLFCGFPIFGAILAGAVVFMATNDLAVLYDSIPIQFYGALEINGLLAIPLFMLVGEIMNQGGLTQRLIAVA
EVLVGRFKGGLAYANLITNAMAASILGSAVAQIGVMSKVMIPEMEKKGYDKAFSGAVTVSAGLLGPIIPPSMLMIIYGVV
AVQPIAPLFIAGIVPGLLIVAVLAGVILLYGMFGSHLPEGSPTPLRDSWGTLVGGIAPGLIPAVVIVGIMSGAMTPTESG
AVASLIALILGFLYRELKLADLPGILRSVAVNTATITGLIAAASVFSWVLAFQGVPDQLVELIAGVTDSPVVFLLLVTLL
MLVLGMFLESISVLIVVVPILMPVVNALGINPIQFGVVCTVATVIGIVTPPVGPGLYIAMVQAHMPMGPLFRATVPFLAA
VLAVVVAICVFPALSTWLPALSAGK
>Mature_425_residues
MITLIVFFALLFCGFPIFGAILAGAVVFMATNDLAVLYDSIPIQFYGALEINGLLAIPLFMLVGEIMNQGGLTQRLIAVA
EVLVGRFKGGLAYANLITNAMAASILGSAVAQIGVMSKVMIPEMEKKGYDKAFSGAVTVSAGLLGPIIPPSMLMIIYGVV
AVQPIAPLFIAGIVPGLLIVAVLAGVILLYGMFGSHLPEGSPTPLRDSWGTLVGGIAPGLIPAVVIVGIMSGAMTPTESG
AVASLIALILGFLYRELKLADLPGILRSVAVNTATITGLIAAASVFSWVLAFQGVPDQLVELIAGVTDSPVVFLLLVTLL
MLVLGMFLESISVLIVVVPILMPVVNALGINPIQFGVVCTVATVIGIVTPPVGPGLYIAMVQAHMPMGPLFRATVPFLAA
VLAVVVAICVFPALSTWLPALSAGK

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=366, Percent_Identity=34.1530054644809, Blast_Score=173, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 43840; Mature: 43840

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLIVFFALLFCGFPIFGAILAGAVVFMATNDLAVLYDSIPIQFYGALEINGLLAIPLF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCEEEEEEEEECHHHHHHHH
MLVGEIMNQGGLTQRLIAVAEVLVGRFKGGLAYANLITNAMAASILGSAVAQIGVMSKVM
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPEMEKKGYDKAFSGAVTVSAGLLGPIIPPSMLMIIYGVVAVQPIAPLFIAGIVPGLLIV
CCCHHHCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLAGVILLYGMFGSHLPEGSPTPLRDSWGTLVGGIAPGLIPAVVIVGIMSGAMTPTESG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AVASLIALILGFLYRELKLADLPGILRSVAVNTATITGLIAAASVFSWVLAFQGVPDQLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ELIAGVTDSPVVFLLLVTLLMLVLGMFLESISVLIVVVPILMPVVNALGINPIQFGVVCT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VATVIGIVTPPVGPGLYIAMVQAHMPMGPLFRATVPFLAAVLAVVVAICVFPALSTWLPA
HHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAGK
HCCCC
>Mature Secondary Structure
MITLIVFFALLFCGFPIFGAILAGAVVFMATNDLAVLYDSIPIQFYGALEINGLLAIPLF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCEEEEEEEEECHHHHHHHH
MLVGEIMNQGGLTQRLIAVAEVLVGRFKGGLAYANLITNAMAASILGSAVAQIGVMSKVM
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPEMEKKGYDKAFSGAVTVSAGLLGPIIPPSMLMIIYGVVAVQPIAPLFIAGIVPGLLIV
CCCHHHCCCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLAGVILLYGMFGSHLPEGSPTPLRDSWGTLVGGIAPGLIPAVVIVGIMSGAMTPTESG
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AVASLIALILGFLYRELKLADLPGILRSVAVNTATITGLIAAASVFSWVLAFQGVPDQLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ELIAGVTDSPVVFLLLVTLLMLVLGMFLESISVLIVVVPILMPVVNALGINPIQFGVVCT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VATVIGIVTPPVGPGLYIAMVQAHMPMGPLFRATVPFLAAVLAVVVAICVFPALSTWLPA
HHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAGK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]