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The map label for this gene is arsC1 [H]

Identifier: 119898642

GI number: 119898642

Start: 2592005

End: 2592502

Strand: Direct

Name: arsC1 [H]

Synonym: azo2351

Alternate gene names: 119898642

Gene position: 2592005-2592502 (Clockwise)

Preceding gene: 119898640

Following gene: 119898643

Centisome position: 59.23

GC content: 68.07

Gene sequence:

>498_bases
ATGTCCGAACGCATCTACCACGTCCTCTTCCTCTGCACTGGCAACTCGGCCCGCAGCATCCTGGCCGAATCCATCCTCAA
CCAGCTCGGCCACGGCCGTTTCGTCGCCCACAGCGCCGGCAGCCATCCCAAGGGCGAGGTGCATCCACTCGCGCTGGAAC
TGCTTGAACGCAACCATCTGCCAACCGCAGGCTTGCGTTCCAAGTCGTGGGACGAGTTCGCCGCGCCCGGCGCGCCCGCG
CTCGATTTCGTGTTCACGGTGTGCGACAACGCCGCCGGCGAGGTCTGCCCGGTGTGGCCGGGGCAGCCGATGACCGCCCA
CTGGGGTCTCGAGGACCCGGCCGAAGCCGAAGGGGACGAAGCCGCCCGCAAGGCGATGAGCGCGGCGCTGCGCCTGCTCA
GCCATCGCATCGGCCTGTTCCTCAGCCTGCCGCTCGCCAAGCTGGACCGTCTCAGTCTGCAGTCGCAATTGCAGGGCATC
GGCCGCGAAGCGGGCTGA

Upstream 100 bases:

>100_bases
CAAAAGCTTCATGTCGCGCCGCCCTTCATTTCGATAATAATGGAATTATCGTTTTTTACCACTCGCTGTTTCGTCCGCCT
CGTCGCTCCCGGAGTCCCCC

Downstream 100 bases:

>100_bases
CGACCGCCGGAACATCGTGCTGGGCATCCCGCCAACAGTTCGATAATATTCGAATCATGGAAACCCTGAACGCCGCCGAA
CTCCTCGCCGCGCTCGGCCA

Product: putative arsenate reductase (glutaredoxin)

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSERIYHVLFLCTGNSARSILAESILNQLGHGRFVAHSAGSHPKGEVHPLALELLERNHLPTAGLRSKSWDEFAAPGAPA
LDFVFTVCDNAAGEVCPVWPGQPMTAHWGLEDPAEAEGDEAARKAMSAALRLLSHRIGLFLSLPLAKLDRLSLQSQLQGI
GREAG

Sequences:

>Translated_165_residues
MSERIYHVLFLCTGNSARSILAESILNQLGHGRFVAHSAGSHPKGEVHPLALELLERNHLPTAGLRSKSWDEFAAPGAPA
LDFVFTVCDNAAGEVCPVWPGQPMTAHWGLEDPAEAEGDEAARKAMSAALRLLSHRIGLFLSLPLAKLDRLSLQSQLQGI
GREAG
>Mature_164_residues
SERIYHVLFLCTGNSARSILAESILNQLGHGRFVAHSAGSHPKGEVHPLALELLERNHLPTAGLRSKSWDEFAAPGAPAL
DFVFTVCDNAAGEVCPVWPGQPMTAHWGLEDPAEAEGDEAARKAMSAALRLLSHRIGLFLSLPLAKLDRLSLQSQLQGIG
REAG

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 17737; Mature: 17606

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIYHVLFLCTGNSARSILAESILNQLGHGRFVAHSAGSHPKGEVHPLALELLERNHL
CCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCC
PTAGLRSKSWDEFAAPGAPALDFVFTVCDNAAGEVCPVWPGQPMTAHWGLEDPAEAEGDE
CCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHH
AARKAMSAALRLLSHRIGLFLSLPLAKLDRLSLQSQLQGIGREAG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SERIYHVLFLCTGNSARSILAESILNQLGHGRFVAHSAGSHPKGEVHPLALELLERNHL
CCCEEEEEEEEECCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHHHCCC
PTAGLRSKSWDEFAAPGAPALDFVFTVCDNAAGEVCPVWPGQPMTAHWGLEDPAEAEGDE
CCCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCCCCHH
AARKAMSAALRLLSHRIGLFLSLPLAKLDRLSLQSQLQGIGREAG
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]