Click here to switch to the map view.

The map label for this gene is cbl [H]

Identifier: 119898618

GI number: 119898618

Start: 2559320

End: 2560276

Strand: Reverse

Name: cbl [H]

Synonym: azo2327

Alternate gene names: 119898618

Gene position: 2560276-2559320 (Counterclockwise)

Preceding gene: 119898630

Following gene: 119898604

Centisome position: 58.51

GC content: 70.01

Gene sequence:

>957_bases
ATGAATGTCAGTCAGCTCCGCCTCGTCCTCGAGGCCATCCGGCAGAATTTCAACCTTTCCGGCGTGGCCAGCAGCCTGTT
CATTTCCCAGCCGGGCGTCAGCCGCCAGATCAAGGAGCTGGAGGACGAACTCGGCGTCGAGCTGTTCGAGCGCCGCGGCA
AGCGCCTGACCGGCCTGACGCCGCCGGGCGAGATGCTGGTGCCGGTGATCGACCGCATCCTGCTCGACGTGCGTAATCTC
AAGCAGGTCGCCGACCGCTTCGCGATCCAGGATTGCGGTCAGCTGCGCATCGCCAGCACCCACACCCAGGCGCGTTATCT
GCTGCCTGCCGCGCTGCACGACTTCCGCGCGCGCTTCCCGAAGGTGAAGCTGGTGCTGCAGCAGGGCACCCCGGCGCAGA
TCGCGGAATGGGTGGCCAATGGCGAGGCCGATCTCGGGGTGTCCACCGAGGCGATCGACCGCCACCGCGACCTGCAGGCG
TTTCCGGTGCGGGAATGGCATCACGCGGTGATCGTGCCGCCGGCGCATCCGCTGGCCGCGGCCGGGGAATTGACGCTGGC
GGCGCTCGCCGAGCATCCGCTGGTGACCTATGGCGAAGGCTTTGCCGGACGCAGCGTGATCGACGCCGCTTTTTCCGCCG
CGGGGCTGGCGCCCGACGTGGTGCTGGCGGCGCTGGACGCCGACGTGATCGTCACCTATGTGGAAGCGGGCTTCGGCGTG
GGCATCGTCGCCGAGATGGCGGCGCGCGGCGCGGCCGCCCGTGGAGGCGTGGCGCAGCTGGACGCGCGCCACCTGTTCGG
ACCCAACGTGGCCCGGGTCGCGGTGCGCCGCGGTGCCTACCTGCGCGAATACGCGCTTGAACTGGTGGCGATGCTGGCGG
CGGAACGCAGCCTGGATGACATCCTGTCCGCGCTGCAGCGCGACCTGGCGCCGCGCGGCGCCGACTGCGCGCACTAG

Upstream 100 bases:

>100_bases
AATTGGTTATCCAATTTCACCGCGGCCACCGAGAATCCGCCGCATTCCGGGCCGGATTGCGGCCGTTCCTCGTCCCTATT
CCAGCGCGCGGTTTGCCAGC

Downstream 100 bases:

>100_bases
ATGCGGCGTGCGCTAGCCCGGGAGCGGCTCCGTATCCGCCGGAGAAGATGCCGCTTCGGCGATCCGGTAGCAGCCGCGCC
CGGCCTTCTTCGCCTCGTAC

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNVSQLRLVLEAIRQNFNLSGVASSLFISQPGVSRQIKELEDELGVELFERRGKRLTGLTPPGEMLVPVIDRILLDVRNL
KQVADRFAIQDCGQLRIASTHTQARYLLPAALHDFRARFPKVKLVLQQGTPAQIAEWVANGEADLGVSTEAIDRHRDLQA
FPVREWHHAVIVPPAHPLAAAGELTLAALAEHPLVTYGEGFAGRSVIDAAFSAAGLAPDVVLAALDADVIVTYVEAGFGV
GIVAEMAARGAAARGGVAQLDARHLFGPNVARVAVRRGAYLREYALELVAMLAAERSLDDILSALQRDLAPRGADCAH

Sequences:

>Translated_318_residues
MNVSQLRLVLEAIRQNFNLSGVASSLFISQPGVSRQIKELEDELGVELFERRGKRLTGLTPPGEMLVPVIDRILLDVRNL
KQVADRFAIQDCGQLRIASTHTQARYLLPAALHDFRARFPKVKLVLQQGTPAQIAEWVANGEADLGVSTEAIDRHRDLQA
FPVREWHHAVIVPPAHPLAAAGELTLAALAEHPLVTYGEGFAGRSVIDAAFSAAGLAPDVVLAALDADVIVTYVEAGFGV
GIVAEMAARGAAARGGVAQLDARHLFGPNVARVAVRRGAYLREYALELVAMLAAERSLDDILSALQRDLAPRGADCAH
>Mature_318_residues
MNVSQLRLVLEAIRQNFNLSGVASSLFISQPGVSRQIKELEDELGVELFERRGKRLTGLTPPGEMLVPVIDRILLDVRNL
KQVADRFAIQDCGQLRIASTHTQARYLLPAALHDFRARFPKVKLVLQQGTPAQIAEWVANGEADLGVSTEAIDRHRDLQA
FPVREWHHAVIVPPAHPLAAAGELTLAALAEHPLVTYGEGFAGRSVIDAAFSAAGLAPDVVLAALDADVIVTYVEAGFGV
GIVAEMAARGAAARGGVAQLDARHLFGPNVARVAVRRGAYLREYALELVAMLAAERSLDDILSALQRDLAPRGADCAH

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=301, Percent_Identity=47.8405315614618, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1787530, Length=305, Percent_Identity=41.9672131147541, Blast_Score=265, Evalue=3e-72,
Organism=Escherichia coli, GI157672245, Length=213, Percent_Identity=34.2723004694836, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790262, Length=256, Percent_Identity=26.5625, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790399, Length=260, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789204, Length=252, Percent_Identity=26.5873015873016, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788887, Length=245, Percent_Identity=29.7959183673469, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082132, Length=125, Percent_Identity=36.8, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788481, Length=244, Percent_Identity=25.8196721311475, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI145693105, Length=238, Percent_Identity=25.6302521008403, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=29.2134831460674, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI2367136, Length=238, Percent_Identity=22.2689075630252, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788748, Length=250, Percent_Identity=26, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787879, Length=246, Percent_Identity=29.6747967479675, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=227, Percent_Identity=28.6343612334802, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34214; Mature: 34214

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSQLRLVLEAIRQNFNLSGVASSLFISQPGVSRQIKELEDELGVELFERRGKRLTGLT
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHCCCEECCCC
PPGEMLVPVIDRILLDVRNLKQVADRFAIQDCGQLRIASTHTQARYLLPAALHDFRARFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCC
KVKLVLQQGTPAQIAEWVANGEADLGVSTEAIDRHRDLQAFPVREWHHAVIVPPAHPLAA
CEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHH
AGELTLAALAEHPLVTYGEGFAGRSVIDAAFSAAGLAPDVVLAALDADVIVTYVEAGFGV
CCHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
GIVAEMAARGAAARGGVAQLDARHLFGPNVARVAVRRGAYLREYALELVAMLAAERSLDD
HHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHH
ILSALQRDLAPRGADCAH
HHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNVSQLRLVLEAIRQNFNLSGVASSLFISQPGVSRQIKELEDELGVELFERRGKRLTGLT
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCHHHHHHCCCEECCCC
PPGEMLVPVIDRILLDVRNLKQVADRFAIQDCGQLRIASTHTQARYLLPAALHDFRARFP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHCC
KVKLVLQQGTPAQIAEWVANGEADLGVSTEAIDRHRDLQAFPVREWHHAVIVPPAHPLAA
CEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCCEEECCCCCCCHH
AGELTLAALAEHPLVTYGEGFAGRSVIDAAFSAAGLAPDVVLAALDADVIVTYVEAGFGV
CCHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCH
GIVAEMAARGAAARGGVAQLDARHLFGPNVARVAVRRGAYLREYALELVAMLAAERSLDD
HHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHCCHHH
ILSALQRDLAPRGADCAH
HHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]