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The map label for this gene is aidB1 [H]

Identifier: 119898590

GI number: 119898590

Start: 2516981

End: 2518624

Strand: Direct

Name: aidB1 [H]

Synonym: azo2299

Alternate gene names: 119898590

Gene position: 2516981-2518624 (Clockwise)

Preceding gene: 119898589

Following gene: 119898591

Centisome position: 57.52

GC content: 72.81

Gene sequence:

>1644_bases
ATGTGGACCACGCACGAAGTCGCCAACCAGGTCGATGCCCTGGTCGACTACAACCTCTTCGCGTGCGACCCCGCGCTGCA
AAACGCGGTCGCGGCGGCGGGCGCGGCAGCGCGGATGGGCGAGCTGGACGCCATCGGTGCCCGCTTGGGCCATGCCGAGG
TACTGCGGCTGGGCGATCTCGCCAACCGCCATCCGCCCCAATTGCACACCCATGACGCGTGCGGCCGGCGCGTTGATCGC
GTCGAGTACCACCCCGCCTGGGATGCGCTGATGCGCCTGCTCTACGCCGATGGCGTGCACTGTTCGGCATGGACCGAGCC
CGGCCCCGGCGCCCACGTCGCGCGCGCGGCGGCGTTCTTCCTGCACGGCCAGGTGGAAGCCGGGTCGCTGTGTCCGGCCA
CGATGACCTTCGCCGCGATCCCGCTGCTGCGCCGCGAACCCGCGCTGCACGCGGCACTGGCGGCGCAACTGGGCGCGCTC
GACTACGACGGCCGCGACCTGCCGGCCCCGTCCAAGCGTTCGGTCACCGTCGGCATGGGCCTCACCGAAAAGCAGGGCGG
CTCCGACCTGCGCAGCGTGGCCACCCAAGCCCGGCGCGCCGCTGGCGGCGAATACCTGCTGGTCGGCCACAAGTGGTTCT
ACTCCGTTCCCGCGTGCGACGGCCACCTCGTGCTGGCGCGCGGCGACGACGGCCCCGCCTGCTTCTTCGTGCCGCGCTGG
CGGCCGGACGGGGAACGCAACGCGGTACGGATCCAGCGCCTGAAGGACAAGCTCGGCAACCGCTCCAACGCCTCCGGCGA
GGTCGAATTCCACGACGCCCTTGGCATCCCCGTGGGCGAGCCGGGGCGCGGCATCGCCGTGCTGATCGAAATGGCCGCGC
AAACCCGGCTCGACTGCGTGCTCGGCAGCGCGGCCCTGATGCGGCGCGCGCTGGTGGAAGCGCTGCACCACGCGCGCCAC
CGCAGCGCCTTCGGCCACCCGCTGATCGCGCAGCCGCTGATGCGCAACGTGCTCGCCGATCTCGCGCTGGAAAGCGAGGC
CGCCACCCTGCTCGCCATCCACCTTGCGGCCTGCGCCGATGCCGAATGCGCAGGCGGCGGCACGGCGGCGCGCGGACGCG
CGTGGCGGCGGGTGCTGACACCGGCTGCCAAATTCTGGATCTGCAAGCGCGCAATCGCGTTCTGCGCCGAATGCATGGAG
GTCTGCGGCGGCAACGGCTACGTCGAAGACGGCCCCATGCCCCGCCTGTTGCGCGAGGCCCCGGTCAATTCGATCTGGGA
AGGTTCGGGCAACGTGATGTGCCTGGACCTGCTGCGCGCCCTCGCCCGCGAGCAGGACGCCGCCGCCGCGCTGCTTGCCG
ACCTGGCGGATGCCGTCGATGGCGACAGGCGGTGGCGTGCCGCCTGCGAAGAGCTGGCGGCCACCCTGAACGCCGGCCGC
GACGATGCCTGGCTGGCGCGCCGCGGCGCGAGCCGTCTGGTGGTGCTGGTGCAGGCCGCCCTGTTGCGTCGCCACGCCCC
CGCGGCGGTGGCCGCCGCCTTTGCCGCCAGCCGGGTGTACCGCCATGGCGACCACGGTTTCGGCGCCCTGCAATCCGCCG
ATGCGGCGGCGCCGCTGCTGGAACGCGCATGGCCCCCGGCCTGA

Upstream 100 bases:

>100_bases
GCTGTCGGACGATGGTGGCGACCACTGGCGCTGCCTGTCGCCCCATCTGCCGCCGATCTACTGCGTGCGCTTCGGCTGAC
GCAGCGCGCGCGGGCACGCG

Downstream 100 bases:

>100_bases
AGCCGCTGCCTGCCGCGGCCCATCCAACGCGGCGCAAAGGCTGGCCGCGCGGCGCCTGCTTCGGTAAAGTTCGGTCAGGG
TGTCATGCCGGCCGGTTGCC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MWTTHEVANQVDALVDYNLFACDPALQNAVAAAGAAARMGELDAIGARLGHAEVLRLGDLANRHPPQLHTHDACGRRVDR
VEYHPAWDALMRLLYADGVHCSAWTEPGPGAHVARAAAFFLHGQVEAGSLCPATMTFAAIPLLRREPALHAALAAQLGAL
DYDGRDLPAPSKRSVTVGMGLTEKQGGSDLRSVATQARRAAGGEYLLVGHKWFYSVPACDGHLVLARGDDGPACFFVPRW
RPDGERNAVRIQRLKDKLGNRSNASGEVEFHDALGIPVGEPGRGIAVLIEMAAQTRLDCVLGSAALMRRALVEALHHARH
RSAFGHPLIAQPLMRNVLADLALESEAATLLAIHLAACADAECAGGGTAARGRAWRRVLTPAAKFWICKRAIAFCAECME
VCGGNGYVEDGPMPRLLREAPVNSIWEGSGNVMCLDLLRALAREQDAAAALLADLADAVDGDRRWRAACEELAATLNAGR
DDAWLARRGASRLVVLVQAALLRRHAPAAVAAAFAASRVYRHGDHGFGALQSADAAAPLLERAWPPA

Sequences:

>Translated_547_residues
MWTTHEVANQVDALVDYNLFACDPALQNAVAAAGAAARMGELDAIGARLGHAEVLRLGDLANRHPPQLHTHDACGRRVDR
VEYHPAWDALMRLLYADGVHCSAWTEPGPGAHVARAAAFFLHGQVEAGSLCPATMTFAAIPLLRREPALHAALAAQLGAL
DYDGRDLPAPSKRSVTVGMGLTEKQGGSDLRSVATQARRAAGGEYLLVGHKWFYSVPACDGHLVLARGDDGPACFFVPRW
RPDGERNAVRIQRLKDKLGNRSNASGEVEFHDALGIPVGEPGRGIAVLIEMAAQTRLDCVLGSAALMRRALVEALHHARH
RSAFGHPLIAQPLMRNVLADLALESEAATLLAIHLAACADAECAGGGTAARGRAWRRVLTPAAKFWICKRAIAFCAECME
VCGGNGYVEDGPMPRLLREAPVNSIWEGSGNVMCLDLLRALAREQDAAAALLADLADAVDGDRRWRAACEELAATLNAGR
DDAWLARRGASRLVVLVQAALLRRHAPAAVAAAFAASRVYRHGDHGFGALQSADAAAPLLERAWPPA
>Mature_547_residues
MWTTHEVANQVDALVDYNLFACDPALQNAVAAAGAAARMGELDAIGARLGHAEVLRLGDLANRHPPQLHTHDACGRRVDR
VEYHPAWDALMRLLYADGVHCSAWTEPGPGAHVARAAAFFLHGQVEAGSLCPATMTFAAIPLLRREPALHAALAAQLGAL
DYDGRDLPAPSKRSVTVGMGLTEKQGGSDLRSVATQARRAAGGEYLLVGHKWFYSVPACDGHLVLARGDDGPACFFVPRW
RPDGERNAVRIQRLKDKLGNRSNASGEVEFHDALGIPVGEPGRGIAVLIEMAAQTRLDCVLGSAALMRRALVEALHHARH
RSAFGHPLIAQPLMRNVLADLALESEAATLLAIHLAACADAECAGGGTAARGRAWRRVLTPAAKFWICKRAIAFCAECME
VCGGNGYVEDGPMPRLLREAPVNSIWEGSGNVMCLDLLRALAREQDAAAALLADLADAVDGDRRWRAACEELAATLNAGR
DDAWLARRGASRLVVLVQAALLRRHAPAAVAAAFAASRVYRHGDHGFGALQSADAAAPLLERAWPPA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=265, Percent_Identity=29.0566037735849, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI7656849, Length=276, Percent_Identity=27.8985507246377, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI226958412, Length=284, Percent_Identity=27.112676056338, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI226958414, Length=284, Percent_Identity=27.8169014084507, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4557231, Length=267, Percent_Identity=25.4681647940075, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI187960098, Length=267, Percent_Identity=25.4681647940075, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4501859, Length=277, Percent_Identity=25.6317689530686, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082384, Length=515, Percent_Identity=49.9029126213592, Blast_Score=457, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI86563383, Length=424, Percent_Identity=30.188679245283, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI86563381, Length=424, Percent_Identity=30.188679245283, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=283, Percent_Identity=28.6219081272085, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=274, Percent_Identity=26.2773722627737, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=319, Percent_Identity=24.7648902821317, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534899, Length=308, Percent_Identity=25, Blast_Score=80, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17570075, Length=269, Percent_Identity=25.6505576208178, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506239, Length=295, Percent_Identity=24.406779661017, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17551932, Length=338, Percent_Identity=24.5562130177515, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17505929, Length=352, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24660351, Length=324, Percent_Identity=25.6172839506173, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356377, Length=295, Percent_Identity=25.4237288135593, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363737, Length=287, Percent_Identity=24.0418118466899, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24646207, Length=275, Percent_Identity=26.1818181818182, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355753, Length=280, Percent_Identity=24.6428571428571, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 58298; Mature: 58298

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWTTHEVANQVDALVDYNLFACDPALQNAVAAAGAAARMGELDAIGARLGHAEVLRLGDL
CCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHH
ANRHPPQLHTHDACGRRVDRVEYHPAWDALMRLLYADGVHCSAWTEPGPGAHVARAAAFF
CCCCCCCCCCCHHHCCHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHH
LHGQVEAGSLCPATMTFAAIPLLRREPALHAALAAQLGALDYDGRDLPAPSKRSVTVGMG
HCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECC
LTEKQGGSDLRSVATQARRAAGGEYLLVGHKWFYSVPACDGHLVLARGDDGPACFFVPRW
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCEEEEEECCCCCEEEEEECC
RPDGERNAVRIQRLKDKLGNRSNASGEVEFHDALGIPVGEPGRGIAVLIEMAAQTRLDCV
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LGSAALMRRALVEALHHARHRSAFGHPLIAQPLMRNVLADLALESEAATLLAIHLAACAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AECAGGGTAARGRAWRRVLTPAAKFWICKRAIAFCAECMEVCGGNGYVEDGPMPRLLREA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
PVNSIWEGSGNVMCLDLLRALAREQDAAAALLADLADAVDGDRRWRAACEELAATLNAGR
CCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
DDAWLARRGASRLVVLVQAALLRRHAPAAVAAAFAASRVYRHGDHGFGALQSADAAAPLL
CHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHH
ERAWPPA
HHCCCCC
>Mature Secondary Structure
MWTTHEVANQVDALVDYNLFACDPALQNAVAAAGAAARMGELDAIGARLGHAEVLRLGDL
CCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHH
ANRHPPQLHTHDACGRRVDRVEYHPAWDALMRLLYADGVHCSAWTEPGPGAHVARAAAFF
CCCCCCCCCCCHHHCCHHHCCCCCCHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHH
LHGQVEAGSLCPATMTFAAIPLLRREPALHAALAAQLGALDYDGRDLPAPSKRSVTVGMG
HCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECC
LTEKQGGSDLRSVATQARRAAGGEYLLVGHKWFYSVPACDGHLVLARGDDGPACFFVPRW
CCCCCCCHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCEEEEEECCCCCEEEEEECC
RPDGERNAVRIQRLKDKLGNRSNASGEVEFHDALGIPVGEPGRGIAVLIEMAAQTRLDCV
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEEHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LGSAALMRRALVEALHHARHRSAFGHPLIAQPLMRNVLADLALESEAATLLAIHLAACAD
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AECAGGGTAARGRAWRRVLTPAAKFWICKRAIAFCAECMEVCGGNGYVEDGPMPRLLREA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
PVNSIWEGSGNVMCLDLLRALAREQDAAAALLADLADAVDGDRRWRAACEELAATLNAGR
CCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
DDAWLARRGASRLVVLVQAALLRRHAPAAVAAAFAASRVYRHGDHGFGALQSADAAAPLL
CHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHH
ERAWPPA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]