Click here to switch to the map view.

The map label for this gene is glpE [H]

Identifier: 119898570

GI number: 119898570

Start: 2498525

End: 2499364

Strand: Direct

Name: glpE [H]

Synonym: azo2279

Alternate gene names: 119898570

Gene position: 2498525-2499364 (Clockwise)

Preceding gene: 119898569

Following gene: 119898571

Centisome position: 57.1

GC content: 70.48

Gene sequence:

>840_bases
ATGACGCAGACCGCCACCCCCGCCCCCGTCACCAGCCGCAGCGGCCATCGCATCTCGGCGGCAGACGCGGCCGACATGCT
GCTGCGCCACCGCGACGGCGTGCTGCCGGCGCTTGCCGTGTTCGACGTGCGCGACGCCGCGCGCTACGCCGCTGCCCACA
TCGAAGGCGCCGAACCGCTCACCGAAGCCGGCTTCCTGACGGTGGCACGGCGCCTGCCCAAGACCGTACCGGTGCTGGTC
TATTGCTATCACGGCAACGCCAGCCAGACCTACGCGCAGATGTTCGCCGACTTCCGTTTTCCCGAGGTCTACAGCGTGGA
TGGCGGCTACGAGGTGTTCGCGGCCGAACTCGCCAAGGCGGAAGCCGCGCGCAGCGGCAGCACGACGCGCACCGCCAGCC
TCAGCCCGACCCTGCTCGAATTCCTCGCTGCCTACGGCTTCGACCCCGATGACCTCGATGCCACCCGCGCGCACGGGCTG
ACCCCGCTGATGCGGGCCTCGCTCGAAGGCCGCGCCGACATCGTCGCCGAACTGCTTGCGGTGGGCGTTTCGATCGCGCG
CCGCAACATGGACGGCAACAACGCGCTGTGGCTGGCCTGCGTGTCCAGCAACGCCGAGGTCGTGCGCCGGCTGGTGGCGG
CCGGCATCGACGTCGACAACCGCAACGACATGGGCGCCACCGCCCTGATGTACACCGCGTCCGCCGGCAAGGCCGACATG
GTGGCGCTGCTGCTCGAGTGCGGCGCCGACCCGCAGATTCCCAACTTCGACGACGCCCGCGCGGTAGATCTGGCCGCCAC
GCGCGACTGCCTCAAGCTGCTGCGCCACACCCTGCGCTGA

Upstream 100 bases:

>100_bases
CGACCCGCGCATCGAATCGACCCCCGGCTACCCCGCCCGCGAACCGCAGCGCGGCTGAACGCGGCGGAAAGAACAACGCC
CCCCGACCAGAGAGACCGCC

Downstream 100 bases:

>100_bases
GCCGCCCATGGTCACCCAACAGCCGCCCAAGTACCGCTCGCTGCTCGCCGTGCTCGACGCCCTTGCCGAGCTGATCGACG
ACGGCCGCCTCGCCGTCAGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTQTATPAPVTSRSGHRISAADAADMLLRHRDGVLPALAVFDVRDAARYAAAHIEGAEPLTEAGFLTVARRLPKTVPVLV
YCYHGNASQTYAQMFADFRFPEVYSVDGGYEVFAAELAKAEAARSGSTTRTASLSPTLLEFLAAYGFDPDDLDATRAHGL
TPLMRASLEGRADIVAELLAVGVSIARRNMDGNNALWLACVSSNAEVVRRLVAAGIDVDNRNDMGATALMYTASAGKADM
VALLLECGADPQIPNFDDARAVDLAATRDCLKLLRHTLR

Sequences:

>Translated_279_residues
MTQTATPAPVTSRSGHRISAADAADMLLRHRDGVLPALAVFDVRDAARYAAAHIEGAEPLTEAGFLTVARRLPKTVPVLV
YCYHGNASQTYAQMFADFRFPEVYSVDGGYEVFAAELAKAEAARSGSTTRTASLSPTLLEFLAAYGFDPDDLDATRAHGL
TPLMRASLEGRADIVAELLAVGVSIARRNMDGNNALWLACVSSNAEVVRRLVAAGIDVDNRNDMGATALMYTASAGKADM
VALLLECGADPQIPNFDDARAVDLAATRDCLKLLRHTLR
>Mature_278_residues
TQTATPAPVTSRSGHRISAADAADMLLRHRDGVLPALAVFDVRDAARYAAAHIEGAEPLTEAGFLTVARRLPKTVPVLVY
CYHGNASQTYAQMFADFRFPEVYSVDGGYEVFAAELAKAEAARSGSTTRTASLSPTLLEFLAAYGFDPDDLDATRAHGLT
PLMRASLEGRADIVAELLAVGVSIARRNMDGNNALWLACVSSNAEVVRRLVAAGIDVDNRNDMGATALMYTASAGKADMV
ALLLECGADPQIPNFDDARAVDLAATRDCLKLLRHTLR

Specific function: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide [H]

COG id: COG0666

COG function: function code R; FOG: Ankyrin repeat

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI87239981, Length=145, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI55741641, Length=118, Percent_Identity=33.0508474576271, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI32967601, Length=114, Percent_Identity=37.719298245614, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.1 [H]

Molecular weight: Translated: 29799; Mature: 29668

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50088 ANK_REPEAT ; PS50297 ANK_REP_REGION ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTATPAPVTSRSGHRISAADAADMLLRHRDGVLPALAVFDVRDAARYAAAHIEGAEPL
CCCCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
TEAGFLTVARRLPKTVPVLVYCYHGNASQTYAQMFADFRFPEVYSVDGGYEVFAAELAKA
HHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
EAARSGSTTRTASLSPTLLEFLAAYGFDPDDLDATRAHGLTPLMRASLEGRADIVAELLA
HHHCCCCCCEECCCCHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHCCCHHHHHHHHHH
VGVSIARRNMDGNNALWLACVSSNAEVVRRLVAAGIDVDNRNDMGATALMYTASAGKADM
HHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHH
VALLLECGADPQIPNFDDARAVDLAATRDCLKLLRHTLR
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQTATPAPVTSRSGHRISAADAADMLLRHRDGVLPALAVFDVRDAARYAAAHIEGAEPL
CCCCCCCCCCCCCCCEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCH
TEAGFLTVARRLPKTVPVLVYCYHGNASQTYAQMFADFRFPEVYSVDGGYEVFAAELAKA
HHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHH
EAARSGSTTRTASLSPTLLEFLAAYGFDPDDLDATRAHGLTPLMRASLEGRADIVAELLA
HHHCCCCCCEECCCCHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHCCCHHHHHHHHHH
VGVSIARRNMDGNNALWLACVSSNAEVVRRLVAAGIDVDNRNDMGATALMYTASAGKADM
HHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHH
VALLLECGADPQIPNFDDARAVDLAATRDCLKLLRHTLR
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA