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The map label for this gene is aat

Identifier: 119898499

GI number: 119898499

Start: 2418999

End: 2419706

Strand: Direct

Name: aat

Synonym: azo2208

Alternate gene names: 119898499

Gene position: 2418999-2419706 (Clockwise)

Preceding gene: 119898498

Following gene: 119898500

Centisome position: 55.28

GC content: 68.36

Gene sequence:

>708_bases
ATGATCCCGTGGCTGACCGACCGCCCGGCGTTTCCGCCTGTTGAACGCGCCCTGACCGAGCCCAACGGCCTGCTCGCCGC
CGGCGGCCGGCTGACGCCCGAATGGCTGCTCGCGGCCTACCGGCGCGGCATCTTTCCGTGGTACAGCGACGGCGAACCCA
TCCTGTGGTGGAGCCCGGACCCACGCCTGGTGCTGCAACCGGCCCAGATCCGCATCACGCGCTCGCTGCGCAAGGTGCTG
CGCGGGCGACGCTTCGAAGTGCGCTTCGACACCGCCTTTGCACGCGTCATCGAAGAATGCGCCGCCCCGCGCGAACCCGG
CGGCGGCACCTGGATCACCCCGGAAATCCGCGCCGCCTATCTGCGGATGCACGAACTGGGCTACGCCCACAGTGTGGAGT
CATGGCTCGACGGCCGCCTCGTCGGGGGCCTCTACGGCATGGCACTGGGGCGCGCCTTCTTCGGCGAATCCATGTTCAGC
CGCGTCAGCGACGCTTCCAAGGTCGCCCTCGCCCACCTCGCCCGCTTCCTTGAGCAGCGCGATTTTGGCGTGATAGATTG
CCAGATGACTACGCCCCACCTGCTCTCCATGGGGGCTCACGAAATCGCCCGGCGCGAGTTCTGCGCGGGCCTGGAACGGT
GGACGGTGGAAGGACCGCCGCCCGCGAAATGGAGCGGAACGACTGCCGCCGAATTCGACTGGAACTGA

Upstream 100 bases:

>100_bases
GGCTCGCGGCGGACCACGTCGTCACCTTCCATACCGACGACGAGGACGAAGCCGCCCCGCCGCAGCAGGTCCCGGAGCCC
GCGCTGGTCCAGCTTTCGTA

Downstream 100 bases:

>100_bases
CGCGCCGTCCGGCGACTCAACTGGAGCGAGCAGGCAATCACGCACGCAGGCGCACGACGATGCAGAAGGACTACCCCTAC
GCCCTGATCCAGTTTTACGC

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MIPWLTDRPAFPPVERALTEPNGLLAAGGRLTPEWLLAAYRRGIFPWYSDGEPILWWSPDPRLVLQPAQIRITRSLRKVL
RGRRFEVRFDTAFARVIEECAAPREPGGGTWITPEIRAAYLRMHELGYAHSVESWLDGRLVGGLYGMALGRAFFGESMFS
RVSDASKVALAHLARFLEQRDFGVIDCQMTTPHLLSMGAHEIARREFCAGLERWTVEGPPPAKWSGTTAAEFDWN

Sequences:

>Translated_235_residues
MIPWLTDRPAFPPVERALTEPNGLLAAGGRLTPEWLLAAYRRGIFPWYSDGEPILWWSPDPRLVLQPAQIRITRSLRKVL
RGRRFEVRFDTAFARVIEECAAPREPGGGTWITPEIRAAYLRMHELGYAHSVESWLDGRLVGGLYGMALGRAFFGESMFS
RVSDASKVALAHLARFLEQRDFGVIDCQMTTPHLLSMGAHEIARREFCAGLERWTVEGPPPAKWSGTTAAEFDWN
>Mature_235_residues
MIPWLTDRPAFPPVERALTEPNGLLAAGGRLTPEWLLAAYRRGIFPWYSDGEPILWWSPDPRLVLQPAQIRITRSLRKVL
RGRRFEVRFDTAFARVIEECAAPREPGGGTWITPEIRAAYLRMHELGYAHSVESWLDGRLVGGLYGMALGRAFFGESMFS
RVSDASKVALAHLARFLEQRDFGVIDCQMTTPHLLSMGAHEIARREFCAGLERWTVEGPPPAKWSGTTAAEFDWN

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=215, Percent_Identity=50.2325581395349, Blast_Score=203, Evalue=7e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_AZOSB (A1K7M0)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_933712.1
- ProteinModelPortal:   A1K7M0
- SMR:   A1K7M0
- STRING:   A1K7M0
- GeneID:   4608733
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2208
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- PhylomeDB:   A1K7M0
- ProtClustDB:   PRK00301
- BioCyc:   ASP62928:AZO2208-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 26538; Mature: 26538

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPWLTDRPAFPPVERALTEPNGLLAAGGRLTPEWLLAAYRRGIFPWYSDGEPILWWSPD
CCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCC
PRLVLQPAQIRITRSLRKVLRGRRFEVRFDTAFARVIEECAAPREPGGGTWITPEIRAAY
CCEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHH
LRMHELGYAHSVESWLDGRLVGGLYGMALGRAFFGESMFSRVSDASKVALAHLARFLEQR
HHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DFGVIDCQMTTPHLLSMGAHEIARREFCAGLERWTVEGPPPAKWSGTTAAEFDWN
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIPWLTDRPAFPPVERALTEPNGLLAAGGRLTPEWLLAAYRRGIFPWYSDGEPILWWSPD
CCCCCCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCC
PRLVLQPAQIRITRSLRKVLRGRRFEVRFDTAFARVIEECAAPREPGGGTWITPEIRAAY
CCEEECCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEECHHHHHHH
LRMHELGYAHSVESWLDGRLVGGLYGMALGRAFFGESMFSRVSDASKVALAHLARFLEQR
HHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DFGVIDCQMTTPHLLSMGAHEIARREFCAGLERWTVEGPPPAKWSGTTAAEFDWN
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA