The gene/protein map for NC_008702 is currently unavailable.
Definition Azoarcus sp. BH72 chromosome, complete genome.
Accession NC_008702
Length 4,376,040

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The map label for this gene is pnp

Identifier: 119898394

GI number: 119898394

Start: 2308958

End: 2311057

Strand: Reverse

Name: pnp

Synonym: azo2103

Alternate gene names: 119898394

Gene position: 2311057-2308958 (Counterclockwise)

Preceding gene: 119898395

Following gene: 119898392

Centisome position: 52.81

GC content: 63.86

Gene sequence:

>2100_bases
TTGCCTACCGCTATCAAGAAAACCTTCACCTACGGCGCCCACACTGTCACGCTGGAAACCGGTGAGGTTGCCCGCCAGGC
CGGCGGCGCCGTCATCGTCAATGTCGATGACACCGTTGTCCTCGCGACCGTCGTCGCCGCCAAGGATGCCAAGCCGGGTC
AGGATTTCTTCCCGCTCACCGTCGACTACGTCGAGAAGTTCTACGCCGCGGGCCGCATCCCCGGCGGCTTCTTCAAGCGC
GAAGGTCGCCCGACCGAGAAGGAAACGCTGACGTCGCGCCTGATCGACCGTCCGATCCGTCCGCTGTTTCCGGAAGGCTT
CTACAACGAAGTCCAGGTGATCGTCACCGTGTTGTCGCTCAACCCGGAAGTCGATGCCGACATCCCGGCGATGATCGCCG
CTTCGGCTGCGCTGTCGATCTCGGGCATCCCGTTCGACGGCCCGATCGGTGCCGCCCGCGTGGGCTACGCGGATGGCCAG
TATCTGCTGAACCCGACCGTCGAGCAGTTGAAGACCAGCAAGCTCAACCTGGTGGTGGCGGGTACCGCGAGCGCGGTGCT
GATGGTCGAATCCGAGGCCGACGAACTGTCCGAGCAGGTCATGCTGGGCGCCGTGGTGTTCGGCCACGAGCAGATGCAGG
CTGCGATCAACGCGATCAACGAACTGGTCGAAGTCGCCGGCAAGCCCGAGTGGAACTGGCAGCCGCCGGCCGCCAACGAT
GCGCTGGTCGCGCGCGTCAAGGAACTGGCGCTGGCGGATGTGGAAGAAGCCTTCCGCATCACCAGCAAGCAGGCCCGTAC
CGAGCGTCTGTCCGAAATCCGCAAGCGCACCATCGCGGCGCTGACCGATGGCGTTGACAATGCGCCGTCCGAGAACGAGA
TCAAGGACATCTTCTTCACGCTGGAAGCCGGCACGGTGCGCAGCCGCATCCTTAACGGCGAGCCGCGCATCGACGGCCGC
GACACCCGCACCGTGCGCCCGATCGACATCCGCGTCGGCGTGCTGCCGCGTACCCATGGCTCGGCGCTGTTCACCCGTGG
GGAAACCCAGGCACTGGTTGTTGCCACGCTGGGCACCGGCCGTGACGAACAGATCATCGATGCCATCGCGGGGGAGTACA
AGGAGCGTTTCATGCTCCACTACAACTTCCCGCCGTTCTCCACGGGCGAAACCGGTCGTTTCGGTGTGACCAAGCGCCGC
GAGATCGGTCATGGCCGCCTGGCCAAGCGCGCACTGGTGGCGATGCTGCCGAAGGGCGAGGACTTCAGCTACACCATCCG
CGTGGTGTCGGAAATTACCGAGTCGAACGGCTCCAGCTCGATGGCGTCGGTGTGCGGCGGCTCGCTTGCGCTGATGGACG
CCGGCGTGCCGATGAAGGACCACGTGGCCGGTATCGCCATGGGTCTGATCAAGGACGGCAACCGCTTCGCGGTGCTGACC
GACATCCTGGGTGACGAGGACCACCTCGGCGACATGGACTTCAAGGTGGCCGGTACCGAAAACGGTGTGACCGCGCTGCA
GATGGACATCAAGATCCAGGGCATCACCAAGGAAATCATGCAGGTCGCGCTGGCGCAGGCCGGCGAAGGCCGTCTGCACA
TTCTCAAGCAGATGAAGGATGCGCTCGGCGTCGCTCGCGGCGAGGTGTCCGAGTTTGCCCCGCGCATGCTCAACATGAAG
ATCAATCCGGAAAAGATCCGCGATGTGATCGGCAAGGGCGGTGCGGTGATTCGCGCGCTGCAGGAAGAAACCGGTACCGT
CATCGAGATCGAGGACGACGGCAGCATCACGATCTCGTCGGTTTCTGCAGAAGGCGCGCAGAAGGCCAAGGCCCGCATCG
AGGACATCACCGCGGAAGTCGAGGTGGGCAAGGTCTACGAAGGCACCGTGGTGCGTCTGCTCGACTTTGGCGCCATCGTG
AACATCCTTCCGGGTCGTGACGGCCTGCTGCACGTCTCCCAGATCGCCAACGAACGCGTCAATAACGTCGGCGACTACGT
CAAGGAAGGCCAGGCGGTGCGCGTGAAGGTGCTCGAGACTGATGAGCGCGGCAAGATCCGCCTCAGCATGAAGGCGCTGT
TGAACGAAAACGCGGGCTGA

Upstream 100 bases:

>100_bases
GGCTCTGTCGTTTTGGGGTTCGGCGTTCTCACGGCGGCCAGCCGTTATCGGGCCGCCATTGCAGTTGTCGTTCGCTGCAC
ATTTCTAGAAAGGAATTCCC

Downstream 100 bases:

>100_bases
TCGGCCGCAGAATGAAAAAAGGGACGCTTCGGCGTCCCTTTTTTTATCCCCCGACGCGTCAGCTCGCGACCTGTCGCTCC
CGGATTTCAGCCAGCGTCTT

Product: polynucleotide phosphorylase/polyadenylase

Products: NA

Alternate protein names: Polynucleotide phosphorylase; PNPase

Number of amino acids: Translated: 699; Mature: 698

Protein sequence:

>699_residues
MPTAIKKTFTYGAHTVTLETGEVARQAGGAVIVNVDDTVVLATVVAAKDAKPGQDFFPLTVDYVEKFYAAGRIPGGFFKR
EGRPTEKETLTSRLIDRPIRPLFPEGFYNEVQVIVTVLSLNPEVDADIPAMIAASAALSISGIPFDGPIGAARVGYADGQ
YLLNPTVEQLKTSKLNLVVAGTASAVLMVESEADELSEQVMLGAVVFGHEQMQAAINAINELVEVAGKPEWNWQPPAAND
ALVARVKELALADVEEAFRITSKQARTERLSEIRKRTIAALTDGVDNAPSENEIKDIFFTLEAGTVRSRILNGEPRIDGR
DTRTVRPIDIRVGVLPRTHGSALFTRGETQALVVATLGTGRDEQIIDAIAGEYKERFMLHYNFPPFSTGETGRFGVTKRR
EIGHGRLAKRALVAMLPKGEDFSYTIRVVSEITESNGSSSMASVCGGSLALMDAGVPMKDHVAGIAMGLIKDGNRFAVLT
DILGDEDHLGDMDFKVAGTENGVTALQMDIKIQGITKEIMQVALAQAGEGRLHILKQMKDALGVARGEVSEFAPRMLNMK
INPEKIRDVIGKGGAVIRALQEETGTVIEIEDDGSITISSVSAEGAQKAKARIEDITAEVEVGKVYEGTVVRLLDFGAIV
NILPGRDGLLHVSQIANERVNNVGDYVKEGQAVRVKVLETDERGKIRLSMKALLNENAG

Sequences:

>Translated_699_residues
MPTAIKKTFTYGAHTVTLETGEVARQAGGAVIVNVDDTVVLATVVAAKDAKPGQDFFPLTVDYVEKFYAAGRIPGGFFKR
EGRPTEKETLTSRLIDRPIRPLFPEGFYNEVQVIVTVLSLNPEVDADIPAMIAASAALSISGIPFDGPIGAARVGYADGQ
YLLNPTVEQLKTSKLNLVVAGTASAVLMVESEADELSEQVMLGAVVFGHEQMQAAINAINELVEVAGKPEWNWQPPAAND
ALVARVKELALADVEEAFRITSKQARTERLSEIRKRTIAALTDGVDNAPSENEIKDIFFTLEAGTVRSRILNGEPRIDGR
DTRTVRPIDIRVGVLPRTHGSALFTRGETQALVVATLGTGRDEQIIDAIAGEYKERFMLHYNFPPFSTGETGRFGVTKRR
EIGHGRLAKRALVAMLPKGEDFSYTIRVVSEITESNGSSSMASVCGGSLALMDAGVPMKDHVAGIAMGLIKDGNRFAVLT
DILGDEDHLGDMDFKVAGTENGVTALQMDIKIQGITKEIMQVALAQAGEGRLHILKQMKDALGVARGEVSEFAPRMLNMK
INPEKIRDVIGKGGAVIRALQEETGTVIEIEDDGSITISSVSAEGAQKAKARIEDITAEVEVGKVYEGTVVRLLDFGAIV
NILPGRDGLLHVSQIANERVNNVGDYVKEGQAVRVKVLETDERGKIRLSMKALLNENAG
>Mature_698_residues
PTAIKKTFTYGAHTVTLETGEVARQAGGAVIVNVDDTVVLATVVAAKDAKPGQDFFPLTVDYVEKFYAAGRIPGGFFKRE
GRPTEKETLTSRLIDRPIRPLFPEGFYNEVQVIVTVLSLNPEVDADIPAMIAASAALSISGIPFDGPIGAARVGYADGQY
LLNPTVEQLKTSKLNLVVAGTASAVLMVESEADELSEQVMLGAVVFGHEQMQAAINAINELVEVAGKPEWNWQPPAANDA
LVARVKELALADVEEAFRITSKQARTERLSEIRKRTIAALTDGVDNAPSENEIKDIFFTLEAGTVRSRILNGEPRIDGRD
TRTVRPIDIRVGVLPRTHGSALFTRGETQALVVATLGTGRDEQIIDAIAGEYKERFMLHYNFPPFSTGETGRFGVTKRRE
IGHGRLAKRALVAMLPKGEDFSYTIRVVSEITESNGSSSMASVCGGSLALMDAGVPMKDHVAGIAMGLIKDGNRFAVLTD
ILGDEDHLGDMDFKVAGTENGVTALQMDIKIQGITKEIMQVALAQAGEGRLHILKQMKDALGVARGEVSEFAPRMLNMKI
NPEKIRDVIGKGGAVIRALQEETGTVIEIEDDGSITISSVSAEGAQKAKARIEDITAEVEVGKVYEGTVVRLLDFGAIVN
ILPGRDGLLHVSQIANERVNNVGDYVKEGQAVRVKVLETDERGKIRLSMKALLNENAG

Specific function: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction

COG id: COG1185

COG function: function code J; Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain

Homologues:

Organism=Homo sapiens, GI188528628, Length=708, Percent_Identity=38.2768361581921, Blast_Score=439, Evalue=1e-123,
Organism=Escherichia coli, GI145693187, Length=691, Percent_Identity=65.9913169319826, Blast_Score=922, Evalue=0.0,
Organism=Caenorhabditis elegans, GI115534063, Length=727, Percent_Identity=34.3878954607978, Blast_Score=342, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI17535281, Length=82, Percent_Identity=46.3414634146341, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362905, Length=732, Percent_Identity=37.1584699453552, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24651641, Length=732, Percent_Identity=37.1584699453552, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24651643, Length=732, Percent_Identity=37.1584699453552, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI161079377, Length=668, Percent_Identity=36.9760479041916, Blast_Score=391, Evalue=1e-109,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1000 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 3328 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media

Swissprot (AC and ID): PNP_AZOSB (A1K7B5)

Other databases:

- EMBL:   AM406670
- RefSeq:   YP_933607.1
- ProteinModelPortal:   A1K7B5
- SMR:   A1K7B5
- STRING:   A1K7B5
- GeneID:   4608625
- GenomeReviews:   AM406670_GR
- KEGG:   azo:azo2103
- eggNOG:   COG1185
- HOGENOM:   HBG382411
- OMA:   YGETVVL
- PhylomeDB:   A1K7B5
- ProtClustDB:   PRK11824
- BioCyc:   ASP62928:AZO2103-MONOMER
- GO:   GO:0005739
- HAMAP:   MF_01595
- InterPro:   IPR001247
- InterPro:   IPR015847
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR012162
- InterPro:   IPR015848
- InterPro:   IPR003029
- InterPro:   IPR020568
- InterPro:   IPR022967
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:1.10.10.400
- PANTHER:   PTHR11252
- PIRSF:   PIRSF005499
- SMART:   SM00322
- SMART:   SM00316
- TIGRFAMs:   TIGR03591

Pfam domain/function: PF00013 KH_1; PF03726 PNPase; PF01138 RNase_PH; PF03725 RNase_PH_C; PF00575 S1; SSF46915 3_ExoRNase; SSF55666 3_ExoRNase; SSF50249 Nucleic_acid_OB; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: =2.7.7.8

Molecular weight: Translated: 75324; Mature: 75193

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50084 KH_TYPE_1; PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MPTAIKKTFTYGAHTVTLETGEVARQAGGAVIVNVDDTVVLATVVAAKDAKPGQDFFPLT
CCCCCCHHEECCCEEEEEECHHHHHHCCCEEEEECCCCEEEHHHHHHCCCCCCCCCCCEE
VDYVEKFYAAGRIPGGFFKREGRPTEKETLTSRLIDRPIRPLFPEGFYNEVQVIVTVLSL
HHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHEEEEECC
NPEVDADIPAMIAASAALSISGIPFDGPIGAARVGYADGQYLLNPTVEQLKTSKLNLVVA
CCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCEECCCCCCEEECCCHHHHCCCCEEEEEE
GTASAVLMVESEADELSEQVMLGAVVFGHEQMQAAINAINELVEVAGKPEWNWQPPAAND
ECCEEEEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
ALVARVKELALADVEEAFRITSKQARTERLSEIRKRTIAALTDGVDNAPSENEIKDIFFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
LEAGTVRSRILNGEPRIDGRDTRTVRPIDIRVGVLPRTHGSALFTRGETQALVVATLGTG
EECCHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEEECCCCCEEEEEEECCC
RDEQIIDAIAGEYKERFMLHYNFPPFSTGETGRFGVTKRREIGHGRLAKRALVAMLPKGE
CCHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCC
DFSYTIRVVSEITESNGSSSMASVCGGSLALMDAGVPMKDHVAGIAMGLIKDGNRFAVLT
CCEEEHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHEECCCEEEEEE
DILGDEDHLGDMDFKVAGTENGVTALQMDIKIQGITKEIMQVALAQAGEGRLHILKQMKD
ECCCCCCCCCCCCEEEECCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALGVARGEVSEFAPRMLNMKINPEKIRDVIGKGGAVIRALQEETGTVIEIEDDGSITISS
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCEEEEE
VSAEGAQKAKARIEDITAEVEVGKVYEGTVVRLLDFGAIVNILPGRDGLLHVSQIANERV
CCCCHHHHHHHHHHHHHEEEEECCEECCHHEEHHHHHHHEEECCCCCCCCHHHHHHHHHH
NNVGDYVKEGQAVRVKVLETDERGKIRLSMKALLNENAG
HHHHHHHHCCCEEEEEEEECCCCCEEEEEEHHHHCCCCC
>Mature Secondary Structure 
PTAIKKTFTYGAHTVTLETGEVARQAGGAVIVNVDDTVVLATVVAAKDAKPGQDFFPLT
CCCCCHHEECCCEEEEEECHHHHHHCCCEEEEECCCCEEEHHHHHHCCCCCCCCCCCEE
VDYVEKFYAAGRIPGGFFKREGRPTEKETLTSRLIDRPIRPLFPEGFYNEVQVIVTVLSL
HHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHEEEEECC
NPEVDADIPAMIAASAALSISGIPFDGPIGAARVGYADGQYLLNPTVEQLKTSKLNLVVA
CCCCCCCCHHHHHHHHHEEECCCCCCCCCCCCEECCCCCCEEECCCHHHHCCCCEEEEEE
GTASAVLMVESEADELSEQVMLGAVVFGHEQMQAAINAINELVEVAGKPEWNWQPPAAND
ECCEEEEEEECCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
ALVARVKELALADVEEAFRITSKQARTERLSEIRKRTIAALTDGVDNAPSENEIKDIFFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
LEAGTVRSRILNGEPRIDGRDTRTVRPIDIRVGVLPRTHGSALFTRGETQALVVATLGTG
EECCHHHHHHCCCCCCCCCCCCCEEEEEEEEEEEEECCCCCEEEECCCCCEEEEEEECCC
RDEQIIDAIAGEYKERFMLHYNFPPFSTGETGRFGVTKRREIGHGRLAKRALVAMLPKGE
CCHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHCCCCCC
DFSYTIRVVSEITESNGSSSMASVCGGSLALMDAGVPMKDHVAGIAMGLIKDGNRFAVLT
CCEEEHHHHHHHHHCCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHHEECCCEEEEEE
DILGDEDHLGDMDFKVAGTENGVTALQMDIKIQGITKEIMQVALAQAGEGRLHILKQMKD
ECCCCCCCCCCCCEEEECCCCCCEEEEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHH
ALGVARGEVSEFAPRMLNMKINPEKIRDVIGKGGAVIRALQEETGTVIEIEDDGSITISS
HHHHHHCCHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCEEEEE
VSAEGAQKAKARIEDITAEVEVGKVYEGTVVRLLDFGAIVNILPGRDGLLHVSQIANERV
CCCCHHHHHHHHHHHHHEEEEECCEECCHHEEHHHHHHHEEECCCCCCCCHHHHHHHHHH
NNVGDYVKEGQAVRVKVLETDERGKIRLSMKALLNENAG
HHHHHHHHCCCEEEEEEEECCCCCEEEEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA