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The map label for this gene is gspD2 [H]

Identifier: 119898381

GI number: 119898381

Start: 2295298

End: 2297325

Strand: Reverse

Name: gspD2 [H]

Synonym: azo2090

Alternate gene names: 119898381

Gene position: 2297325-2295298 (Counterclockwise)

Preceding gene: 119898382

Following gene: 119898380

Centisome position: 52.5

GC content: 69.43

Gene sequence:

>2028_bases
ATGATTGCTCACCGCCGCAAGATCCGCCTGCTGTTGCCCTGTCTGATCGCCGCCCTCGGGGCGTGCGCCACCAATCCCGC
GCTGGAGCGCAGCCGCGAGGCCTTCGCCAGCGGCGACCGCATGGCAGCGCTGATGAGCCTGAAGGACGAGGTCGGGCGCG
ATCCGCGCAACCATGAACTGCGCGCCTATTACCTGCGGCAACGCGAGCTGCTGGGATCGGAAAAGCTCGCCGCCGCCGAA
CGTGCGCGCCTGGCCGGTCGCGCCGAAGAAGCCGAGCGCCTGTATGCGGACGCGCTTCGCATCGACCCCGACCATCCGCG
GGCGCGCGTCGGTGCCGACGAAATCGCTGCCGACCGCAGACGCGCGGCGCGGCTGGAAGAGGCCCGCGCCAGCCTCGGCC
GCGGCGACATCCTGGCGGCCGAGCGCAGCGCCCGCACCGTGCTGGCCGAGCAGCCCGCCAACGGCGCAGCCCGCCAGTTG
TTGCGCGAGATCGACGAGAAGGCCGAGCTGGCCGCGGCAGCGGCCGCACCCGCGCCGGGCGGGCCGCTGTCGCGTCCGGT
AACGCTGGAGTTCCGCGAAGCGCCGCTGCGTGTGGTGTTCGAGGCGCTGGCGCGCGCAAGCGGGCTCAACTTCGTGTTCG
ACCGCGATGTGCGGGCGGAATCGAAGGTGACGCTGTTCGTGCGCAGCAGCACCATCGAAGAGGTGCTCGGCCTGATCGGC
GCCACCCAGCAGCTGGAGCGCAAGATGCTCAACGCCAACTCGGTGTTGGTGTATCCCGCCACGCCGGCAAAGCAGAAGGA
ATACGTCGAGCTGGTCACCCGCAGCTTCTATCTCGCCAACGCCGACGCCAAACAGGCGATGACGATGGTGCGCCAGCTGG
TGAAGAGCAAGGATGTGTTCGTCGACGAAAAGCTGAACATGGTGGTGATCAAGGACACGCCCGATGCGGTGCGTCTGGCC
GAACGCGTGCTTGCCTCGCTCGATGTCGCCGAGCCGGAGGTGATGCTCGAGGTGGAGGTGCTGGAGGTGAGCCGCAACAA
GTTGCAGGACCTCGGCATCGAGTACCCGACGCAGGTCGGCTACGGCTTGCTGACGCCCAACGTGACCAGCACCGTGTCCA
CCGCCGCCGGCTTTGCCACCAGCACCACGCTGGGTGGCGAGCTTGCGAAAGGCATGATCAACCTGCGCGACCGCGGCTCG
CTCGTGCCCTACGTGTCCAACCCAGGCGCGGTGCTCAACCTGCGCGCCGAGGATGGCGACACCAGCCTGCTCGCCAATCC
GCGCATCCGCGTAAAGAACCGCGAGAAGGCCAAGATCCACATCGGCGAGAAGCTGCCGGTATTCACCACCACCGCGACCG
CCAACGTGGGCGTTTCCGCGTCGGTGAACTACCTCGACGTGGGTCTGAAACTGGATGTGGAACCGGCGGTGACGCTGGAA
GACGAGGTGGTGATCAAGGTGGCGCTTGAGGTGAGCAGCATCGTCAAGGAGGTCACCGGCCCCTCCAGTTCGCTCGCGTA
CCAGGTCGGCACCCGCAGCGCGGCGACCACGCTGCGGCTCGCCAATGGCGAGACCCAGGTGCTCGCCGGCCTCATCAACG
ACGAGGAGCGTTCCAGCGCGCGGCGCTTGCCGGGGTTGGGCGAGTTGCCCGTGGTCGGCCGCCTGTTCTCGGCCCAGCGC
GACAGCAATACGAAAACCGAGGTGGTGCTGCTGATCACGCCGCGCATCGTCCGCAACGTGGTGGCCCCCTCGCTGGCGCG
GGCCGACCTGCCCGCCGGCACTGAAGCCGCCGTGGGGGCGCGCCAACTGCGCTTGCGCCCCACCGCACCCAATTCGGTCA
GCATGCAGGGCGGCGCCCAGCCGGGTGGCGCCGCGCGCGCGGAGCCGGTTGTGCTGGAGCGTCCCGAGCCGGTGGCCGAG
GCGGAGGAGGGCAGCGCGCCGGCAGCCGGCTCCATTCCGGTTGCGCCGCCGCAGCTTCCCGCCGCCGGCACGCCGCCGGA
ACCCGACAACGGCAGGGACGAGCGGTGA

Upstream 100 bases:

>100_bases
AGATCGACAGCCGCTACCGCGTCGAGCGTGTCGACGCCGCCGCGATCGAATTCACCTACTTGCCGCTCAAGCAGCGCCAG
ATCCTTCCCGTCGCCAATTC

Downstream 100 bases:

>100_bases
CGCAGCGGGCAACGGGATTCACGCTGATCGAACTGGTGGTCACGGTGGCGATCATCGGCGTACTGGTGGCCGGGGCGGTG
CCCTTGCTGGAACTGGGTGC

Product: general secretion pathway protein D

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MIAHRRKIRLLLPCLIAALGACATNPALERSREAFASGDRMAALMSLKDEVGRDPRNHELRAYYLRQRELLGSEKLAAAE
RARLAGRAEEAERLYADALRIDPDHPRARVGADEIAADRRRAARLEEARASLGRGDILAAERSARTVLAEQPANGAARQL
LREIDEKAELAAAAAAPAPGGPLSRPVTLEFREAPLRVVFEALARASGLNFVFDRDVRAESKVTLFVRSSTIEEVLGLIG
ATQQLERKMLNANSVLVYPATPAKQKEYVELVTRSFYLANADAKQAMTMVRQLVKSKDVFVDEKLNMVVIKDTPDAVRLA
ERVLASLDVAEPEVMLEVEVLEVSRNKLQDLGIEYPTQVGYGLLTPNVTSTVSTAAGFATSTTLGGELAKGMINLRDRGS
LVPYVSNPGAVLNLRAEDGDTSLLANPRIRVKNREKAKIHIGEKLPVFTTTATANVGVSASVNYLDVGLKLDVEPAVTLE
DEVVIKVALEVSSIVKEVTGPSSSLAYQVGTRSAATTLRLANGETQVLAGLINDEERSSARRLPGLGELPVVGRLFSAQR
DSNTKTEVVLLITPRIVRNVVAPSLARADLPAGTEAAVGARQLRLRPTAPNSVSMQGGAQPGGAARAEPVVLERPEPVAE
AEEGSAPAAGSIPVAPPQLPAAGTPPEPDNGRDER

Sequences:

>Translated_675_residues
MIAHRRKIRLLLPCLIAALGACATNPALERSREAFASGDRMAALMSLKDEVGRDPRNHELRAYYLRQRELLGSEKLAAAE
RARLAGRAEEAERLYADALRIDPDHPRARVGADEIAADRRRAARLEEARASLGRGDILAAERSARTVLAEQPANGAARQL
LREIDEKAELAAAAAAPAPGGPLSRPVTLEFREAPLRVVFEALARASGLNFVFDRDVRAESKVTLFVRSSTIEEVLGLIG
ATQQLERKMLNANSVLVYPATPAKQKEYVELVTRSFYLANADAKQAMTMVRQLVKSKDVFVDEKLNMVVIKDTPDAVRLA
ERVLASLDVAEPEVMLEVEVLEVSRNKLQDLGIEYPTQVGYGLLTPNVTSTVSTAAGFATSTTLGGELAKGMINLRDRGS
LVPYVSNPGAVLNLRAEDGDTSLLANPRIRVKNREKAKIHIGEKLPVFTTTATANVGVSASVNYLDVGLKLDVEPAVTLE
DEVVIKVALEVSSIVKEVTGPSSSLAYQVGTRSAATTLRLANGETQVLAGLINDEERSSARRLPGLGELPVVGRLFSAQR
DSNTKTEVVLLITPRIVRNVVAPSLARADLPAGTEAAVGARQLRLRPTAPNSVSMQGGAQPGGAARAEPVVLERPEPVAE
AEEGSAPAAGSIPVAPPQLPAAGTPPEPDNGRDER
>Mature_675_residues
MIAHRRKIRLLLPCLIAALGACATNPALERSREAFASGDRMAALMSLKDEVGRDPRNHELRAYYLRQRELLGSEKLAAAE
RARLAGRAEEAERLYADALRIDPDHPRARVGADEIAADRRRAARLEEARASLGRGDILAAERSARTVLAEQPANGAARQL
LREIDEKAELAAAAAAPAPGGPLSRPVTLEFREAPLRVVFEALARASGLNFVFDRDVRAESKVTLFVRSSTIEEVLGLIG
ATQQLERKMLNANSVLVYPATPAKQKEYVELVTRSFYLANADAKQAMTMVRQLVKSKDVFVDEKLNMVVIKDTPDAVRLA
ERVLASLDVAEPEVMLEVEVLEVSRNKLQDLGIEYPTQVGYGLLTPNVTSTVSTAAGFATSTTLGGELAKGMINLRDRGS
LVPYVSNPGAVLNLRAEDGDTSLLANPRIRVKNREKAKIHIGEKLPVFTTTATANVGVSASVNYLDVGLKLDVEPAVTLE
DEVVIKVALEVSSIVKEVTGPSSSLAYQVGTRSAATTLRLANGETQVLAGLINDEERSSARRLPGLGELPVVGRLFSAQR
DSNTKTEVVLLITPRIVRNVVAPSLARADLPAGTEAAVGARQLRLRPTAPNSVSMQGGAQPGGAARAEPVVLERPEPVAE
AEEGSAPAAGSIPVAPPQLPAAGTPPEPDNGRDER

Specific function: Required for type IV pilus biogenesis and competence. Could function as a pore for exit of the pilus but also as a channel for entry of heme and antimicrobial agents and uptake of transforming DNA [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=425, Percent_Identity=22.5882352941176, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082242, Length=284, Percent_Identity=27.112676056338, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 72267; Mature: 72267

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAHRRKIRLLLPCLIAALGACATNPALERSREAFASGDRMAALMSLKDEVGRDPRNHEL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCH
RAYYLRQRELLGSEKLAAAERARLAGRAEEAERLYADALRIDPDHPRARVGADEIAADRR
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RAARLEEARASLGRGDILAAERSARTVLAEQPANGAARQLLREIDEKAELAAAAAAPAPG
HHHHHHHHHHHCCCCCEEECCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GPLSRPVTLEFREAPLRVVFEALARASGLNFVFDRDVRAESKVTLFVRSSTIEEVLGLIG
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHC
ATQQLERKMLNANSVLVYPATPAKQKEYVELVTRSFYLANADAKQAMTMVRQLVKSKDVF
CHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCE
VDEKLNMVVIKDTPDAVRLAERVLASLDVAEPEVMLEVEVLEVSRNKLQDLGIEYPTQVG
EECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCC
YGLLTPNVTSTVSTAAGFATSTTLGGELAKGMINLRDRGSLVPYVSNPGAVLNLRAEDGD
CEEECCCHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCCCCEECCCCEEEEEEECCCC
TSLLANPRIRVKNREKAKIHIGEKLPVFTTTATANVGVSASVNYLDVGLKLDVEPAVTLE
CEEEECCEEEECCCCCEEEEECCCCCEEEEECCCCCCCEEECEEEEEEEEEECCCCEEEC
DEVVIKVALEVSSIVKEVTGPSSSLAYQVGTRSAATTLRLANGETQVLAGLINDEERSSA
CCEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCEEHEEHHCCHHHHHH
RRLPGLGELPVVGRLFSAQRDSNTKTEVVLLITPRIVRNVVAPSLARADLPAGTEAAVGA
HCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHCCC
RQLRLRPTAPNSVSMQGGAQPGGAARAEPVVLERPEPVAEAEEGSAPAAGSIPVAPPQLP
CCEEEECCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
AAGTPPEPDNGRDER
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MIAHRRKIRLLLPCLIAALGACATNPALERSREAFASGDRMAALMSLKDEVGRDPRNHEL
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCH
RAYYLRQRELLGSEKLAAAERARLAGRAEEAERLYADALRIDPDHPRARVGADEIAADRR
HHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RAARLEEARASLGRGDILAAERSARTVLAEQPANGAARQLLREIDEKAELAAAAAAPAPG
HHHHHHHHHHHCCCCCEEECCCCHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
GPLSRPVTLEFREAPLRVVFEALARASGLNFVFDRDVRAESKVTLFVRSSTIEEVLGLIG
CCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHC
ATQQLERKMLNANSVLVYPATPAKQKEYVELVTRSFYLANADAKQAMTMVRQLVKSKDVF
CHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHCCCCE
VDEKLNMVVIKDTPDAVRLAERVLASLDVAEPEVMLEVEVLEVSRNKLQDLGIEYPTQVG
EECCCCEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCCCCC
YGLLTPNVTSTVSTAAGFATSTTLGGELAKGMINLRDRGSLVPYVSNPGAVLNLRAEDGD
CEEECCCHHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCCCCEECCCCEEEEEEECCCC
TSLLANPRIRVKNREKAKIHIGEKLPVFTTTATANVGVSASVNYLDVGLKLDVEPAVTLE
CEEEECCEEEECCCCCEEEEECCCCCEEEEECCCCCCCEEECEEEEEEEEEECCCCEEEC
DEVVIKVALEVSSIVKEVTGPSSSLAYQVGTRSAATTLRLANGETQVLAGLINDEERSSA
CCEEEEEHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCCEEHEEHHCCHHHHHH
RRLPGLGELPVVGRLFSAQRDSNTKTEVVLLITPRIVRNVVAPSLARADLPAGTEAAVGA
HCCCCCCCCCHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHCCC
RQLRLRPTAPNSVSMQGGAQPGGAARAEPVVLERPEPVAEAEEGSAPAAGSIPVAPPQLP
CCEEEECCCCCCEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCC
AAGTPPEPDNGRDER
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]