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The map label for this gene is xanB [H]

Identifier: 119898376

GI number: 119898376

Start: 2291561

End: 2293009

Strand: Reverse

Name: xanB [H]

Synonym: azo2085

Alternate gene names: 119898376

Gene position: 2293009-2291561 (Counterclockwise)

Preceding gene: 119898377

Following gene: 119898375

Centisome position: 52.4

GC content: 66.87

Gene sequence:

>1449_bases
ATGACCATCAAGAGCGTCATCCTTTCCGGGGGCTCCGGCACCCGCTTGTGGCCCGCATCGCGCGAAACCTACCCCAAGCA
ACTCCTTCCGCTTACCGGCGAACTGTCTCTGCTGCAGGAGACCGCGGTGCGTCTGAAGGATTTCGCGGGCGAGGTGGATC
CGGTGCCGCTGGTTGTCACCAACGAAGACTACCGCTTCATCATTGCCGAGCAGCTGCGCCAAATTGGCGTCGCGAGCGCT
GGCATCGTGCTCGAGCCGGTCGGGCGCAATACCGCGCCGGCGCTGACGCTTGCCGCGCTTGCTGCCGCGGCCGGAGGCAA
CGATCCGGTGCTGCTGGTGATGCCGGCCGACCACGTCATCACCGACGTCGAGCGCTTCCAGTTGGCCATCGGCGAGGGTG
CCGCACTGGCGTCGGCGGGCGCGCTGGTCACCTTCGGCATCGTGCCGGACCACCCGGAGACAGGCTACGGCTACATCCGG
GTGGGCCCGGCGGTTTCCGGCGCGGCGACGTCGCGCGTGCTGGCCGAGTTCGTCGAGAAGCCGGACGCGCCGACGGCCGA
GCGCTACGTCGCCAGCGGCGAATACTTCTGGAACAGCGGCATTTTCATGATGAAGGCCTCGGTGTGGCTACGTGCCATCG
AGCGCTTCAACCCAGAGATGGCCGCGGCGTGCGAGGCCGCGTTCGTGGAACGCAAGGCCGATGCGGACTTCCTGCGCGTC
GGCAAGGGTGCCTTCGAGAACTGCCCCTCGGATTCGATCGACTACGCGGTGATGGAGAAGCTCCAGTCGGCGCCGGAGGT
CGGGCAGGGCGTGGTGGTGCCGTTGTCGGCGGGGTGGTCGGACGTGGGCGCGTGGGACGCGCTGTGGGCGGTTTCCCCCA
AGGATGCGTCCGGCAACAGTGCGCGCGGCGAGGTGTTGTTCGAGTCCAGCCGCAATACGCTGGTGCATGCCAGCACCCGC
CTGGTGGCCGCCGTGGGTTGTGACGACATGGTGGTGGTGGAGACGGCCGACGCGGTAATGGTGGCCCACAAGAGCCACAC
CCAGTCGGTGAAGAACGTGGTCGCCCGGCTCAAGGCCGAGGGCCGCAGCCTCACCCGCACGCACCGCAAGGTTTACCGGC
CTTGGGGCTGGTACGACTCGATCGACGCGGGCGACCGCTTCCAGGTCAAGCGCATCGTGGTCAATCCGGGCGCCAAGCTC
AGCCTGCAGATGCACTACCACAGGGCGGAGCACTGGATTGTCGTCCGTGGCACCGCTGAAGTGACTGCAGGCGACAAGGT
CTTCCTGCTCGGCGAAAACGAGTCGACCTACATTCCGCTCGGCCACACCCATCGGCTGACGAATCCCGGCAAGGTGCCGC
TGGAGATCATCGAGGTCCAGTCCGGCAGCTACCTGGGCGAAGACGACATCGTGCGTTTCGAGGACACCTACGGGCGCACC
GAGGGCTGA

Upstream 100 bases:

>100_bases
GTTGTGTCGGCGCGCACCGCATGCCGCCGCGATGGCCTATCATCCGCGCCATCCGATACGCACGCGTATCGCCGCATAAG
TTCGAGCGAGGTTCAGCACC

Downstream 100 bases:

>100_bases
TGAGGCGCCGGTAGTCCGCGGCGAGGCCGGCGGTGCCCGGATCGGGCACAATCAGGCGTTTTCGGCAGGACTTCCGGCAT
GACCTCAGTCGTCCGCCCTC

Product: xanthan biosynthesis protein XanB

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MTIKSVILSGGSGTRLWPASRETYPKQLLPLTGELSLLQETAVRLKDFAGEVDPVPLVVTNEDYRFIIAEQLRQIGVASA
GIVLEPVGRNTAPALTLAALAAAAGGNDPVLLVMPADHVITDVERFQLAIGEGAALASAGALVTFGIVPDHPETGYGYIR
VGPAVSGAATSRVLAEFVEKPDAPTAERYVASGEYFWNSGIFMMKASVWLRAIERFNPEMAAACEAAFVERKADADFLRV
GKGAFENCPSDSIDYAVMEKLQSAPEVGQGVVVPLSAGWSDVGAWDALWAVSPKDASGNSARGEVLFESSRNTLVHASTR
LVAAVGCDDMVVVETADAVMVAHKSHTQSVKNVVARLKAEGRSLTRTHRKVYRPWGWYDSIDAGDRFQVKRIVVNPGAKL
SLQMHYHRAEHWIVVRGTAEVTAGDKVFLLGENESTYIPLGHTHRLTNPGKVPLEIIEVQSGSYLGEDDIVRFEDTYGRT
EG

Sequences:

>Translated_482_residues
MTIKSVILSGGSGTRLWPASRETYPKQLLPLTGELSLLQETAVRLKDFAGEVDPVPLVVTNEDYRFIIAEQLRQIGVASA
GIVLEPVGRNTAPALTLAALAAAAGGNDPVLLVMPADHVITDVERFQLAIGEGAALASAGALVTFGIVPDHPETGYGYIR
VGPAVSGAATSRVLAEFVEKPDAPTAERYVASGEYFWNSGIFMMKASVWLRAIERFNPEMAAACEAAFVERKADADFLRV
GKGAFENCPSDSIDYAVMEKLQSAPEVGQGVVVPLSAGWSDVGAWDALWAVSPKDASGNSARGEVLFESSRNTLVHASTR
LVAAVGCDDMVVVETADAVMVAHKSHTQSVKNVVARLKAEGRSLTRTHRKVYRPWGWYDSIDAGDRFQVKRIVVNPGAKL
SLQMHYHRAEHWIVVRGTAEVTAGDKVFLLGENESTYIPLGHTHRLTNPGKVPLEIIEVQSGSYLGEDDIVRFEDTYGRT
EG
>Mature_481_residues
TIKSVILSGGSGTRLWPASRETYPKQLLPLTGELSLLQETAVRLKDFAGEVDPVPLVVTNEDYRFIIAEQLRQIGVASAG
IVLEPVGRNTAPALTLAALAAAAGGNDPVLLVMPADHVITDVERFQLAIGEGAALASAGALVTFGIVPDHPETGYGYIRV
GPAVSGAATSRVLAEFVEKPDAPTAERYVASGEYFWNSGIFMMKASVWLRAIERFNPEMAAACEAAFVERKADADFLRVG
KGAFENCPSDSIDYAVMEKLQSAPEVGQGVVVPLSAGWSDVGAWDALWAVSPKDASGNSARGEVLFESSRNTLVHASTRL
VAAVGCDDMVVVETADAVMVAHKSHTQSVKNVVARLKAEGRSLTRTHRKVYRPWGWYDSIDAGDRFQVKRIVVNPGAKLS
LQMHYHRAEHWIVVRGTAEVTAGDKVFLLGENESTYIPLGHTHRLTNPGKVPLEIIEVQSGSYLGEDDIVRFEDTYGRTE
G

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=478, Percent_Identity=54.602510460251, Blast_Score=511, Evalue=1e-146,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51955; Mature: 51824

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKSVILSGGSGTRLWPASRETYPKQLLPLTGELSLLQETAVRLKDFAGEVDPVPLVVT
CCCHHEEEECCCCCEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
NEDYRFIIAEQLRQIGVASAGIVLEPVGRNTAPALTLAALAAAAGGNDPVLLVMPADHVI
CCCCEEHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHH
TDVERFQLAIGEGAALASAGALVTFGIVPDHPETGYGYIRVGPAVSGAATSRVLAEFVEK
HHHHHHEEEECCCCHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
PDAPTAERYVASGEYFWNSGIFMMKASVWLRAIERFNPEMAAACEAAFVERKADADFLRV
CCCCCHHHHEECCCEEECCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
GKGAFENCPSDSIDYAVMEKLQSAPEVGQGVVVPLSAGWSDVGAWDALWAVSPKDASGNS
CCCHHHCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCC
ARGEVLFESSRNTLVHASTRLVAAVGCDDMVVVETADAVMVAHKSHTQSVKNVVARLKAE
CCCEEEEECCCCEEEEECEEEEEEECCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHC
GRSLTRTHRKVYRPWGWYDSIDAGDRFQVKRIVVNPGAKLSLQMHYHRAEHWIVVRGTAE
CCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCEEEEEECCEE
VTAGDKVFLLGENESTYIPLGHTHRLTNPGKVPLEIIEVQSGSYLGEDDIVRFEDTYGRT
EECCCEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCC
EG
CC
>Mature Secondary Structure 
TIKSVILSGGSGTRLWPASRETYPKQLLPLTGELSLLQETAVRLKDFAGEVDPVPLVVT
CCHHEEEECCCCCEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEE
NEDYRFIIAEQLRQIGVASAGIVLEPVGRNTAPALTLAALAAAAGGNDPVLLVMPADHVI
CCCCEEHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHH
TDVERFQLAIGEGAALASAGALVTFGIVPDHPETGYGYIRVGPAVSGAATSRVLAEFVEK
HHHHHHEEEECCCCHHHCCCCEEEEEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHC
PDAPTAERYVASGEYFWNSGIFMMKASVWLRAIERFNPEMAAACEAAFVERKADADFLRV
CCCCCHHHHEECCCEEECCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHH
GKGAFENCPSDSIDYAVMEKLQSAPEVGQGVVVPLSAGWSDVGAWDALWAVSPKDASGNS
CCCHHHCCCCCCCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCC
ARGEVLFESSRNTLVHASTRLVAAVGCDDMVVVETADAVMVAHKSHTQSVKNVVARLKAE
CCCEEEEECCCCEEEEECEEEEEEECCCCEEEEEECCEEEEEECHHHHHHHHHHHHHHHC
GRSLTRTHRKVYRPWGWYDSIDAGDRFQVKRIVVNPGAKLSLQMHYHRAEHWIVVRGTAE
CCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEEEEEECCCEEEEEECCEE
VTAGDKVFLLGENESTYIPLGHTHRLTNPGKVPLEIIEVQSGSYLGEDDIVRFEDTYGRT
EECCCEEEEEECCCCEEEECCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCC
EG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]