Click here to switch to the map view.

The map label for this gene is speE1 [H]

Identifier: 119898344

GI number: 119898344

Start: 2254352

End: 2255107

Strand: Direct

Name: speE1 [H]

Synonym: azo2053

Alternate gene names: 119898344

Gene position: 2254352-2255107 (Clockwise)

Preceding gene: 119898343

Following gene: 119898348

Centisome position: 51.52

GC content: 66.67

Gene sequence:

>756_bases
ATGAGTACACCGATCGACATTTCCGAGGAGGCCGGTGTCCGTTACCTCCACTTTGGCTCCGACTGGGTACAGGGGGCGAT
GCGCATCCGCAAACCCAATGCGCTCGAACTTGCCTACACGCGGGAGATGATGGCCGGCCTTCTGCTGCGCGGGGACTTGC
CGTGGCCGCGGCGGGTACTGGTGATCGGACTGGGCGCCGCGTCGCTGACCAAATTCATCCACCTGCACTGTCCGGAGGCG
CAACTGCATGTGGTGGAGATCGAGCCGGCGGTGGTGGCCGCGGCGCGCCAGTTCTTCCGCCTGCCGGCCGAAGACGCGCG
TTTTCGCATCCATGTCGGCGACGGTGCCCGTTACGTGCTGGAATCGCCGCGGCAGTATGACTACATCCTGGTCGACGGCT
ACGACCGTAATGCCCGTGCCGGCGCCCTGGACACCCTGCCGTTCTATCAGGCGGCGCGCGCCCGCCTGAGCGAAGACGGC
CTGCTGGCGGTTAACCTCTTCGGTCGGTCGCGCGGCTACAAGGCGAGCGTGGAACGCGTGTTCTCGGCCTTCGACGACCG
GGCGATTGCATTTCCCTCGTGCGATAGCGGCAACGTGGTGGCCTTTGCCGCGGTGGGTGAGCGGATCGACTTGCCGGTGA
GGGACATCCGCCAGCGCGCCGAGGCGCTCAAGACGCGGACCGGGCTGGACCTGCTGCCTACCGTAACCCGGCTGGAACAG
GCAGGCAGCCTCCCGGGCGGAAGCCTGCTGCTGTAA

Upstream 100 bases:

>100_bases
TCTCGCACCCGGTGCTGATTGCACTGGCGGAGATCGATCCCGACAGCCTGAGTCCGCGTGAAGCCCTGGAACGCCTGTAC
GCCTTGAAGCGCCTGAGTGC

Downstream 100 bases:

>100_bases
CGGCTCAGGCCGCCACGGCCTCGGGCTCGGGCGGAATCCACAGACACAGCCCCTTGTTGGCCTTGGCGATGTCGGCAAGG
TTGGCAGCGTGCGCCTCGCA

Product: putative spermidine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MSTPIDISEEAGVRYLHFGSDWVQGAMRIRKPNALELAYTREMMAGLLLRGDLPWPRRVLVIGLGAASLTKFIHLHCPEA
QLHVVEIEPAVVAAARQFFRLPAEDARFRIHVGDGARYVLESPRQYDYILVDGYDRNARAGALDTLPFYQAARARLSEDG
LLAVNLFGRSRGYKASVERVFSAFDDRAIAFPSCDSGNVVAFAAVGERIDLPVRDIRQRAEALKTRTGLDLLPTVTRLEQ
AGSLPGGSLLL

Sequences:

>Translated_251_residues
MSTPIDISEEAGVRYLHFGSDWVQGAMRIRKPNALELAYTREMMAGLLLRGDLPWPRRVLVIGLGAASLTKFIHLHCPEA
QLHVVEIEPAVVAAARQFFRLPAEDARFRIHVGDGARYVLESPRQYDYILVDGYDRNARAGALDTLPFYQAARARLSEDG
LLAVNLFGRSRGYKASVERVFSAFDDRAIAFPSCDSGNVVAFAAVGERIDLPVRDIRQRAEALKTRTGLDLLPTVTRLEQ
AGSLPGGSLLL
>Mature_250_residues
STPIDISEEAGVRYLHFGSDWVQGAMRIRKPNALELAYTREMMAGLLLRGDLPWPRRVLVIGLGAASLTKFIHLHCPEAQ
LHVVEIEPAVVAAARQFFRLPAEDARFRIHVGDGARYVLESPRQYDYILVDGYDRNARAGALDTLPFYQAARARLSEDGL
LAVNLFGRSRGYKASVERVFSAFDDRAIAFPSCDSGNVVAFAAVGERIDLPVRDIRQRAEALKTRTGLDLLPTVTRLEQA
GSLPGGSLLL

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

Organism=Homo sapiens, GI55956895, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI42542405, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI42542403, Length=129, Percent_Identity=31.7829457364341, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 27719; Mature: 27588

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPIDISEEAGVRYLHFGSDWVQGAMRIRKPNALELAYTREMMAGLLLRGDLPWPRRVL
CCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEE
VIGLGAASLTKFIHLHCPEAQLHVVEIEPAVVAAARQFFRLPAEDARFRIHVGDGARYVL
EEECCHHHHHHHHEEECCCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEC
ESPRQYDYILVDGYDRNARAGALDTLPFYQAARARLSEDGLLAVNLFGRSRGYKASVERV
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHH
FSAFDDRAIAFPSCDSGNVVAFAAVGERIDLPVRDIRQRAEALKTRTGLDLLPTVTRLEQ
HHHHCCCEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGSLPGGSLLL
HCCCCCCCCCC
>Mature Secondary Structure 
STPIDISEEAGVRYLHFGSDWVQGAMRIRKPNALELAYTREMMAGLLLRGDLPWPRRVL
CCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCCCCEEE
VIGLGAASLTKFIHLHCPEAQLHVVEIEPAVVAAARQFFRLPAEDARFRIHVGDGARYVL
EEECCHHHHHHHHEEECCCCEEEEEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEC
ESPRQYDYILVDGYDRNARAGALDTLPFYQAARARLSEDGLLAVNLFGRSRGYKASVERV
CCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHH
FSAFDDRAIAFPSCDSGNVVAFAAVGERIDLPVRDIRQRAEALKTRTGLDLLPTVTRLEQ
HHHHCCCEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGSLPGGSLLL
HCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]