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The map label for this gene is gdhAlpha2

Identifier: 119898232

GI number: 119898232

Start: 2130993

End: 2132576

Strand: Reverse

Name: gdhAlpha2

Synonym: azo1941

Alternate gene names: NA

Gene position: 2132576-2130993 (Counterclockwise)

Preceding gene: 119898233

Following gene: 119898231

Centisome position: 48.73

GC content: 70.64

Gene sequence:

>1584_bases
ATGAGAACACTGGACGCAACCGAAGTCGTCGTCGTTGGCGCCGGCCAGGCCGGCAGCCTCGTCGCCGCCAAGCTCGCCGC
CGCCGGAAAGCAGGTGACGGTGTTCGAAGCCGGCGCCGCACGCGGCACCGAAGCGCTCCTGAGTTCGCAGATCTGGGCGC
GCCGGCTGAAAGGCACGCCGGATCTCGCGGCCAGCGCCGGCGATCATCCGCTGGGCATCACGTTCAACACCGGTCAGGGC
GCCGGCGGCACCGCCGCCCACCATTACGCGTGCTGGTTCCGCCTGCATCCGGAGGATTTCGAGATGCAGCGCCGCCACGG
CGTGGCCGCCGACTGGCCGTTCGGTTACGACACGCTGCGTCCGCACTACGACGCGGTGCAGGAGGAGGTGGGCATCGCAG
GTGACGCCGCGGCGGAACGCTGGCGCCCACCCGGCGCGGAGTATCCGCTACCGCCGATGCCGCGCTTCCGTCAGGGCGAA
ATCCTGGCGCGCGGTTTCGAGCGCCACGGCCTGCACGTCGCGCCGCTGCCGCTGGCGATTGCCACCGCGCCTTATCGCGG
CCGCGAGGCCTGCATCTACGACGGCTGGTGCGACGCGGGCTGTCCCACCGGCGCGCTCGCGAACCCGCTGGTGACGTATC
TGAAGTGGGCGCAGACCGCCGGCGCGAAGTTGAACTACCGCCACCGCGTCGAGCGCATCGTCACCGACGCCGCAGGCACG
CGCAGCATCGGCGTGATCGTGGCCCGGCCCGACGGCGAGCGGGTGTTCCAGCCCGCTGCGCTGGTGGTGCTTGCCGCCTT
TGCGCTGGAAACGCCGCGCCTGCTGCTGGCCTCCGCCACCGACCGCCATCCGCAGGGGCTGGCCAACGCGTCCGGCACCG
TCGGCTGCTACCTGCACACGCACGCAGCCGGGGGCGTCTTCGGCCTGTTCGACGAAACCACCGACTGCCACCTGGGCGTC
AGCGGCGGGCAGCTCGTCTGCCAGGACGGTTACGGCAAGGCGAAGGGCGAGGGCAAGGGCAAGGACTTCATCGGCGGCTA
CCAGTGGCTGATCGCGCACTCGACCAAGCCCAACGACCTGCTCGGCATCGCCTGCAGCCGGCCCGACCTGCACGGCAGCG
CTTTCAACAGCTTCATGGGCCAGGCCGCCACGCACTTCGCCTCGATGACGGCGGTGGGCGAAACCCTGCCGCTGGCCGAG
AACCGCGTCGAACTTGCACCGGGCACCGACAGCGCCGGCATGGCGAAGATGCGCGTGGTCCATCGCTTCGACGACAACGC
GCTGCGGCTGTACGCCCATGCGATGAAGGAGGGCGTGGCGATCTTCAACAGCGCCGGCGCGCGCGAGGCCTGGCATGGCC
CGATGGCGAGCATGCATCTGATCGGCGGCACCCGCATGGGCAGCGACCCCGCAACTTCGGTTGCCGATGGCTGGGGCCGC
TGTCACGAGCTGGCCAACGTGTTCATCGCCGGCCCCGGGCTGTTCCCCAGCGGCGGCGCAGTCAATCCCACCTTCACGGC
GTCGGCACTGGCACACCGCACCGCTGCGCACCTGGTGGCGAACTGGCGCGATTACGCCGCATAG

Upstream 100 bases:

>100_bases
CCCGCGCCGGCATTGAACGGCTGGGCCTGGACTACCGCGCCCATGTGGAACCGCCCGTGCGCTGGCCGGGCGAAACTGCG
GCGACGGGGAGGCTGCGCGG

Downstream 100 bases:

>100_bases
CCGCCCCGTGCGGCGGCGCGTCGATTGACGGTGTCAGGCGCACGTCGTACCGTGGGCGCCCCCAAACGCCCGCAGGACAC
CGCCATGACCCAGCCGATTC

Product: putative glucose dehydrogenase subunit alpha

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 527; Mature: 527

Protein sequence:

>527_residues
MRTLDATEVVVVGAGQAGSLVAAKLAAAGKQVTVFEAGAARGTEALLSSQIWARRLKGTPDLAASAGDHPLGITFNTGQG
AGGTAAHHYACWFRLHPEDFEMQRRHGVAADWPFGYDTLRPHYDAVQEEVGIAGDAAAERWRPPGAEYPLPPMPRFRQGE
ILARGFERHGLHVAPLPLAIATAPYRGREACIYDGWCDAGCPTGALANPLVTYLKWAQTAGAKLNYRHRVERIVTDAAGT
RSIGVIVARPDGERVFQPAALVVLAAFALETPRLLLASATDRHPQGLANASGTVGCYLHTHAAGGVFGLFDETTDCHLGV
SGGQLVCQDGYGKAKGEGKGKDFIGGYQWLIAHSTKPNDLLGIACSRPDLHGSAFNSFMGQAATHFASMTAVGETLPLAE
NRVELAPGTDSAGMAKMRVVHRFDDNALRLYAHAMKEGVAIFNSAGAREAWHGPMASMHLIGGTRMGSDPATSVADGWGR
CHELANVFIAGPGLFPSGGAVNPTFTASALAHRTAAHLVANWRDYAA

Sequences:

>Translated_527_residues
MRTLDATEVVVVGAGQAGSLVAAKLAAAGKQVTVFEAGAARGTEALLSSQIWARRLKGTPDLAASAGDHPLGITFNTGQG
AGGTAAHHYACWFRLHPEDFEMQRRHGVAADWPFGYDTLRPHYDAVQEEVGIAGDAAAERWRPPGAEYPLPPMPRFRQGE
ILARGFERHGLHVAPLPLAIATAPYRGREACIYDGWCDAGCPTGALANPLVTYLKWAQTAGAKLNYRHRVERIVTDAAGT
RSIGVIVARPDGERVFQPAALVVLAAFALETPRLLLASATDRHPQGLANASGTVGCYLHTHAAGGVFGLFDETTDCHLGV
SGGQLVCQDGYGKAKGEGKGKDFIGGYQWLIAHSTKPNDLLGIACSRPDLHGSAFNSFMGQAATHFASMTAVGETLPLAE
NRVELAPGTDSAGMAKMRVVHRFDDNALRLYAHAMKEGVAIFNSAGAREAWHGPMASMHLIGGTRMGSDPATSVADGWGR
CHELANVFIAGPGLFPSGGAVNPTFTASALAHRTAAHLVANWRDYAA
>Mature_527_residues
MRTLDATEVVVVGAGQAGSLVAAKLAAAGKQVTVFEAGAARGTEALLSSQIWARRLKGTPDLAASAGDHPLGITFNTGQG
AGGTAAHHYACWFRLHPEDFEMQRRHGVAADWPFGYDTLRPHYDAVQEEVGIAGDAAAERWRPPGAEYPLPPMPRFRQGE
ILARGFERHGLHVAPLPLAIATAPYRGREACIYDGWCDAGCPTGALANPLVTYLKWAQTAGAKLNYRHRVERIVTDAAGT
RSIGVIVARPDGERVFQPAALVVLAAFALETPRLLLASATDRHPQGLANASGTVGCYLHTHAAGGVFGLFDETTDCHLGV
SGGQLVCQDGYGKAKGEGKGKDFIGGYQWLIAHSTKPNDLLGIACSRPDLHGSAFNSFMGQAATHFASMTAVGETLPLAE
NRVELAPGTDSAGMAKMRVVHRFDDNALRLYAHAMKEGVAIFNSAGAREAWHGPMASMHLIGGTRMGSDPATSVADGWGR
CHELANVFIAGPGLFPSGGAVNPTFTASALAHRTAAHLVANWRDYAA

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 55648; Mature: 55648

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLDATEVVVVGAGQAGSLVAAKLAAAGKQVTVFEAGAARGTEALLSSQIWARRLKGTP
CCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
DLAASAGDHPLGITFNTGQGAGGTAAHHYACWFRLHPEDFEMQRRHGVAADWPFGYDTLR
CHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCC
PHYDAVQEEVGIAGDAAAERWRPPGAEYPLPPMPRFRQGEILARGFERHGLHVAPLPLAI
CHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCEEE
ATAPYRGREACIYDGWCDAGCPTGALANPLVTYLKWAQTAGAKLNYRHRVERIVTDAAGT
ECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
RSIGVIVARPDGERVFQPAALVVLAAFALETPRLLLASATDRHPQGLANASGTVGCYLHT
CEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEE
HAAGGVFGLFDETTDCHLGVSGGQLVCQDGYGKAKGEGKGKDFIGGYQWLIAHSTKPNDL
CCCCCEEEECCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCE
LGIACSRPDLHGSAFNSFMGQAATHFASMTAVGETLPLAENRVELAPGTDSAGMAKMRVV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHH
HRFDDNALRLYAHAMKEGVAIFNSAGAREAWHGPMASMHLIGGTRMGSDPATSVADGWGR
HHCCCCHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHH
CHELANVFIAGPGLFPSGGAVNPTFTASALAHRTAAHLVANWRDYAA
HHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTLDATEVVVVGAGQAGSLVAAKLAAAGKQVTVFEAGAARGTEALLSSQIWARRLKGTP
CCCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCC
DLAASAGDHPLGITFNTGQGAGGTAAHHYACWFRLHPEDFEMQRRHGVAADWPFGYDTLR
CHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHCCCCCCCCCCCCCCC
PHYDAVQEEVGIAGDAAAERWRPPGAEYPLPPMPRFRQGEILARGFERHGLHVAPLPLAI
CHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEECCCEEE
ATAPYRGREACIYDGWCDAGCPTGALANPLVTYLKWAQTAGAKLNYRHRVERIVTDAAGT
ECCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCC
RSIGVIVARPDGERVFQPAALVVLAAFALETPRLLLASATDRHPQGLANASGTVGCYLHT
CEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEEE
HAAGGVFGLFDETTDCHLGVSGGQLVCQDGYGKAKGEGKGKDFIGGYQWLIAHSTKPNDL
CCCCCEEEECCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCE
LGIACSRPDLHGSAFNSFMGQAATHFASMTAVGETLPLAENRVELAPGTDSAGMAKMRVV
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHH
HRFDDNALRLYAHAMKEGVAIFNSAGAREAWHGPMASMHLIGGTRMGSDPATSVADGWGR
HHCCCCHHHHHHHHHHCCCEEECCCCCCHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHH
CHELANVFIAGPGLFPSGGAVNPTFTASALAHRTAAHLVANWRDYAA
HHHHHHEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]