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The map label for this gene is lapH [H]

Identifier: 119898145

GI number: 119898145

Start: 2037507

End: 2038310

Strand: Direct

Name: lapH [H]

Synonym: azo1854

Alternate gene names: 119898145

Gene position: 2037507-2038310 (Clockwise)

Preceding gene: 119898144

Following gene: 119898146

Centisome position: 46.56

GC content: 68.53

Gene sequence:

>804_bases
ATGAGCCAGAACCTGACCCTGTCGCGCGAGGACATCGTGCGCCTGTGCGAACGCGTGGAAGGTGCGCAGACCCGCGCCTA
CGCCATCCCCAAACTCACCGACGAATACCCGGCGATGACCATCGCCGACGGCTACGCGGTGCAGAGCGAGCTGCGCCGCC
GCTACCTCGCCCAAGGCCATCGGCTGGTGGGCTGGAAGGCGGGGCTGACCTCGAAGGCGAAGATGAAGCAGATGGGCGTG
GATGTGCCGTCCATCGGCTTCCTCACCGACCGCATGGCGCGGCCGGAGAACGCCGCGATTTCCACTGGCGACCTGGTGCA
CCCGCGCGTCGAGTGCGAGGTGGCTTTCGTGATGAAGCGCGAACTGCGCGGCCCCGGCTGTACCGCGGCGGACGTGCTGG
CGGCTACCGACTACGTGCTGCCGGCGGTAGAGATCATCGATTCGCGCTTTGCCGGCTTCAAGTTCGACCTGCCCAGCGTG
ATCGCCGACAACGGTTCGTCGGCGCGTTTCGTCGGCGGCGGGCGGGCGCGCTACGTCGAGGAGCTGGACCTGCGCACGCT
CGGCGTGGTGCTGGAAAAGAACGGCGAGATCGTCGCGATGGGCGCCTCGGCGGCGGTGCTCGGCCATCCGGCCGAGGCCA
TCGCGATGCTGGTGAACATCCTCGCCGACCTGGGCGAGACGCTGCCGGCGGGCAGCTTCGTGATGAGCGGCGGCATTACC
GAGGCGATTGCGGTGCAGCCGGGCGACAGCGTGGTCGCGCGCTTCCAGGAACTGGGCAGCGTGTCGATGCGCTTCGTGGC
CTGA

Upstream 100 bases:

>100_bases
CGCAGTCGGCGCTGGTGCCGGTGGCCGATGGCGACGAACTGGTGTGCACCGTGGGCGGGCTTGGCAGCTGTCGGGTGAAG
TTCGCGGGGAGGAGTGCGGT

Downstream 100 bases:

>100_bases
GCGATTTCAAGGGGGAGACATGCCAATCATCGAGATGCACCTGATGGAGGGGCGCACCGTCGAGCAGAAGCGGGCGGTGG
CGCAGGCCGTTACCGAGGCG

Product: 4-oxalocrotonate decarboxylase

Products: NA

Alternate protein names: 4-OD [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSQNLTLSREDIVRLCERVEGAQTRAYAIPKLTDEYPAMTIADGYAVQSELRRRYLAQGHRLVGWKAGLTSKAKMKQMGV
DVPSIGFLTDRMARPENAAISTGDLVHPRVECEVAFVMKRELRGPGCTAADVLAATDYVLPAVEIIDSRFAGFKFDLPSV
IADNGSSARFVGGGRARYVEELDLRTLGVVLEKNGEIVAMGASAAVLGHPAEAIAMLVNILADLGETLPAGSFVMSGGIT
EAIAVQPGDSVVARFQELGSVSMRFVA

Sequences:

>Translated_267_residues
MSQNLTLSREDIVRLCERVEGAQTRAYAIPKLTDEYPAMTIADGYAVQSELRRRYLAQGHRLVGWKAGLTSKAKMKQMGV
DVPSIGFLTDRMARPENAAISTGDLVHPRVECEVAFVMKRELRGPGCTAADVLAATDYVLPAVEIIDSRFAGFKFDLPSV
IADNGSSARFVGGGRARYVEELDLRTLGVVLEKNGEIVAMGASAAVLGHPAEAIAMLVNILADLGETLPAGSFVMSGGIT
EAIAVQPGDSVVARFQELGSVSMRFVA
>Mature_266_residues
SQNLTLSREDIVRLCERVEGAQTRAYAIPKLTDEYPAMTIADGYAVQSELRRRYLAQGHRLVGWKAGLTSKAKMKQMGVD
VPSIGFLTDRMARPENAAISTGDLVHPRVECEVAFVMKRELRGPGCTAADVLAATDYVLPAVEIIDSRFAGFKFDLPSVI
ADNGSSARFVGGGRARYVEELDLRTLGVVLEKNGEIVAMGASAAVLGHPAEAIAMLVNILADLGETLPAGSFVMSGGITE
AIAVQPGDSVVARFQELGSVSMRFVA

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=259, Percent_Identity=32.046332046332, Blast_Score=138, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017630
- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.1.1.77 [H]

Molecular weight: Translated: 28545; Mature: 28414

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNLTLSREDIVRLCERVEGAQTRAYAIPKLTDEYPAMTIADGYAVQSELRRRYLAQGH
CCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHCCC
RLVGWKAGLTSKAKMKQMGVDVPSIGFLTDRMARPENAAISTGDLVHPRVECEVAFVMKR
EEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ELRGPGCTAADVLAATDYVLPAVEIIDSRFAGFKFDLPSVIADNGSSARFVGGGRARYVE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHCCCCCEEEECCCHHHHHH
ELDLRTLGVVLEKNGEIVAMGASAAVLGHPAEAIAMLVNILADLGETLPAGSFVMSGGIT
HHHHHHEEEEEECCCCEEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
EAIAVQPGDSVVARFQELGSVSMRFVA
EEEEECCCHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
SQNLTLSREDIVRLCERVEGAQTRAYAIPKLTDEYPAMTIADGYAVQSELRRRYLAQGH
CCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHCCC
RLVGWKAGLTSKAKMKQMGVDVPSIGFLTDRMARPENAAISTGDLVHPRVECEVAFVMKR
EEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHH
ELRGPGCTAADVLAATDYVLPAVEIIDSRFAGFKFDLPSVIADNGSSARFVGGGRARYVE
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCHHHHCCCCCEEEECCCHHHHHH
ELDLRTLGVVLEKNGEIVAMGASAAVLGHPAEAIAMLVNILADLGETLPAGSFVMSGGIT
HHHHHHEEEEEECCCCEEEECCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
EAIAVQPGDSVVARFQELGSVSMRFVA
EEEEECCCHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1732207 [H]