BacMap

Definition	Azoarcus sp. BH72 chromosome, complete genome.
Accession	NC_008702
Length	4,376,040

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The map label for this gene is lapC [H]

Identifier: 119898143

GI number: 119898143

Start: 2034874

End: 2036334

Strand: Direct

Name: lapC [H]

Synonym: azo1852

Alternate gene names: 119898143

Gene position: 2034874-2036334 (Clockwise)

Preceding gene: 119898141

Following gene: 119898144

Centisome position: 46.5

GC content: 66.39

Gene sequence:

>1461_bases
ATGCGTCAGATCGAGAATTTCATCGCCGGCGAATACGTGGCTGCGGCCAGCGGGCGGCGCTTCGAGAAGCGGTCGCCGGT
GGATAACAGGGTGATCGCCTCGATCAGCGAGGCCGGCCGGCCGGAGGTGGATGCGGCGGTGCAGGCGGCGCGCGCGGCGC
TGCATGGCGAATGGGGTGGGCTCACCGCCGACCAGCGCGTCGAGTTGCTGTATGGCGTGGCCAACGAGATTACCCGCCGC
TTCGAGGACTTCGTTGAGGCCGAGACGGCCGATACCGGCCAGCCTTCGCATGTGATGCGCCATGTGTTCATCCCGCGCGG
CGCGGCCAATTTCAAGGTCTTCGCCGACGTGGTGAAGAACGTGCCGACCGAGGCTTTCCAGATGGCGACGCCGGACGGCG
CCGGGGCGCTGAACTATGCGATCCGCGTGCCCAAGGGCGTGATCGGCGTGATCTGCCCGTGGAACGCGCCTTTTCTGCTG
ATGACCTGGAAGCTGGGACCGGCGCTGGCCTGCGGCAACACCGTGGTGGTGAAGCCCTCCGAGGAAACGCCGAACACCGC
CGCCTTGCTGGGCGAGGTGATGAACGCGGTGGGCGTGCCCAAGGGTGTGTACAACGTGGTGAATGGCTTCGGGCCGGATT
CGGCCGGCGCCTTCCTCACCCAGCATCCCGGCGTGGATGCGATCACCTTCACCGGCGAGACCCGCACCGGCGCGGCGATC
ATGAAGGCGGCATCCGAGGGCATGCGCGATGTGTCTTTCGAGTTGGGTGGCAAGAACGCCGGCATCGTGTTCGCGGATGC
GGATTTCGACGCCGCGGTGGATGGCATCTTCCGCTCCGCCTTCCTCAACACCGGGCAGGTCTGCCTCGGCACCGAGCGGG
TGTATGTGGAGCGGCCGATCTTCGAGCGCTTCGTGCAGGCGCTGAAGCTGAAGGCCGAGGCGGTGAAGTACGGCCGCCCG
GAGGACCACACCGCCAACTACGGCCCGCTGATCAGCCAGGAGCACAAGCGCAAGGTGCTGTCCTACTACGCCAAGGCGGT
GGAGGAGGGCGCCACCGTGGTGACCGGCGGCGGCGTGCCCGACATGCCGGGCGAACTGGCCGAAGGCGCCTGGGTGCAGC
CGACGATCTGGACCGGCCTGCCCGAAACCGCCGCGGTGGTGCGCGAGGAAATCTTCGGCCCCTGCTGCCACATCCGCCCC
TTCGACAGCGAACAGGAAGTGGTCGCGCTGGCCAATGCCACCGACTACGGGCTTTCGACCACGATCTGGACGACCAATCT
CGCCCGTGCCCACCGTGTTGCGGCGCGGGTGGAGGTGGGGATTACCTGGATCAACAGCTGGTTCTTGCGTGATTTGAGGA
CGGCGTTTGGGGGGTCGAAGCAGTCCGGTATAGGACGCGAGGGCGGGGTGCATTCGCTGGAGTTCTATACGGAGACGCGG
AATGTTTGCGTGAAGTTGTAG

Upstream 100 bases:

>100_bases
GTATTTCTCGCGCTTCTTAGACTCCGTTTCGAATAGAACCCAACGCCATCCCGCCGCTTCCCAAGGCAGCGCGGCGGCGG
GGCGGATAACGGAGGAGCAG

Downstream 100 bases:

>100_bases
GGGCGGGTGGCCACTGCTCCCTCCCCTTCAAGGGGGTGAAGCAGGGGTTTCGGCAAACATCGTTTGCCGCCTGCTGAACG
ACGAAGCGAAGCGAAGGCTC

Product: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase

Products: 5-carboxymethyl-2-hydroxymuconate; NADH; H+

Alternate protein names: HMSD [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MRQIENFIAGEYVAAASGRRFEKRSPVDNRVIASISEAGRPEVDAAVQAARAALHGEWGGLTADQRVELLYGVANEITRR
FEDFVEAETADTGQPSHVMRHVFIPRGAANFKVFADVVKNVPTEAFQMATPDGAGALNYAIRVPKGVIGVICPWNAPFLL
MTWKLGPALACGNTVVVKPSEETPNTAALLGEVMNAVGVPKGVYNVVNGFGPDSAGAFLTQHPGVDAITFTGETRTGAAI
MKAASEGMRDVSFELGGKNAGIVFADADFDAAVDGIFRSAFLNTGQVCLGTERVYVERPIFERFVQALKLKAEAVKYGRP
EDHTANYGPLISQEHKRKVLSYYAKAVEEGATVVTGGGVPDMPGELAEGAWVQPTIWTGLPETAAVVREEIFGPCCHIRP
FDSEQEVVALANATDYGLSTTIWTTNLARAHRVAARVEVGITWINSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTETR
NVCVKL

Sequences:

>Translated_486_residues
MRQIENFIAGEYVAAASGRRFEKRSPVDNRVIASISEAGRPEVDAAVQAARAALHGEWGGLTADQRVELLYGVANEITRR
FEDFVEAETADTGQPSHVMRHVFIPRGAANFKVFADVVKNVPTEAFQMATPDGAGALNYAIRVPKGVIGVICPWNAPFLL
MTWKLGPALACGNTVVVKPSEETPNTAALLGEVMNAVGVPKGVYNVVNGFGPDSAGAFLTQHPGVDAITFTGETRTGAAI
MKAASEGMRDVSFELGGKNAGIVFADADFDAAVDGIFRSAFLNTGQVCLGTERVYVERPIFERFVQALKLKAEAVKYGRP
EDHTANYGPLISQEHKRKVLSYYAKAVEEGATVVTGGGVPDMPGELAEGAWVQPTIWTGLPETAAVVREEIFGPCCHIRP
FDSEQEVVALANATDYGLSTTIWTTNLARAHRVAARVEVGITWINSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTETR
NVCVKL
>Mature_486_residues
MRQIENFIAGEYVAAASGRRFEKRSPVDNRVIASISEAGRPEVDAAVQAARAALHGEWGGLTADQRVELLYGVANEITRR
FEDFVEAETADTGQPSHVMRHVFIPRGAANFKVFADVVKNVPTEAFQMATPDGAGALNYAIRVPKGVIGVICPWNAPFLL
MTWKLGPALACGNTVVVKPSEETPNTAALLGEVMNAVGVPKGVYNVVNGFGPDSAGAFLTQHPGVDAITFTGETRTGAAI
MKAASEGMRDVSFELGGKNAGIVFADADFDAAVDGIFRSAFLNTGQVCLGTERVYVERPIFERFVQALKLKAEAVKYGRP
EDHTANYGPLISQEHKRKVLSYYAKAVEEGATVVTGGGVPDMPGELAEGAWVQPTIWTGLPETAAVVREEIFGPCCHIRP
FDSEQEVVALANATDYGLSTTIWTTNLARAHRVAARVEVGITWINSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTETR
NVCVKL

Specific function: 2-hydroxymuconic acid semialdehyde can be converted to 2-hydroxypent-2,4-dienoate either directly by the action of 2- hydroxymuconic semialdehyde hydrolase (HMSH) or by the action of three sequential enzymes, the first of which is HMSD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=487, Percent_Identity=39.0143737166324, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI153266822, Length=490, Percent_Identity=37.3469387755102, Blast_Score=312, Evalue=4e-85,
Organism=Homo sapiens, GI25952152, Length=487, Percent_Identity=35.9342915811088, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI115387104, Length=487, Percent_Identity=36.5503080082135, Blast_Score=309, Evalue=4e-84,
Organism=Homo sapiens, GI25777724, Length=483, Percent_Identity=35.1966873706004, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI25777732, Length=488, Percent_Identity=35.4508196721311, Blast_Score=292, Evalue=6e-79,
Organism=Homo sapiens, GI25777730, Length=483, Percent_Identity=35.8178053830228, Blast_Score=285, Evalue=8e-77,
Organism=Homo sapiens, GI21361176, Length=489, Percent_Identity=34.1513292433538, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI25777728, Length=427, Percent_Identity=35.1288056206089, Blast_Score=269, Evalue=5e-72,
Organism=Homo sapiens, GI238814322, Length=483, Percent_Identity=33.3333333333333, Blast_Score=265, Evalue=7e-71,
Organism=Homo sapiens, GI21614513, Length=480, Percent_Identity=34.375, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI301500698, Length=487, Percent_Identity=32.2381930184805, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI25777726, Length=482, Percent_Identity=31.5352697095436, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI4507229, Length=489, Percent_Identity=34.1513292433538, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI25777721, Length=502, Percent_Identity=33.4661354581673, Blast_Score=213, Evalue=2e-55,
Organism=Homo sapiens, GI11095441, Length=484, Percent_Identity=27.4793388429752, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI188035924, Length=473, Percent_Identity=27.4841437632135, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI310128093, Length=466, Percent_Identity=27.4678111587983, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310128103, Length=466, Percent_Identity=27.4678111587983, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI310128091, Length=344, Percent_Identity=31.9767441860465, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI206597441, Length=358, Percent_Identity=30.7262569832402, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI206597439, Length=358, Percent_Identity=30.7262569832402, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI22907049, Length=358, Percent_Identity=30.7262569832402, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI4557303, Length=347, Percent_Identity=29.3948126801153, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI73466520, Length=346, Percent_Identity=28.9017341040462, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI223972651, Length=345, Percent_Identity=28.695652173913, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI310128089, Length=331, Percent_Identity=31.4199395770393, Blast_Score=133, Evalue=4e-31,
Organism=Homo sapiens, GI310128097, Length=259, Percent_Identity=34.7490347490347, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI4502043, Length=344, Percent_Identity=29.3604651162791, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI238814371, Length=344, Percent_Identity=29.3604651162791, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI71773324, Length=344, Percent_Identity=29.3604651162791, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI73695881, Length=343, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI73695879, Length=343, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI310128095, Length=319, Percent_Identity=30.4075235109718, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI223972653, Length=348, Percent_Identity=27.5862068965517, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI238859541, Length=352, Percent_Identity=26.1363636363636, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI25777736, Length=354, Percent_Identity=25.9887005649718, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI25777734, Length=354, Percent_Identity=25.9887005649718, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI310128087, Length=282, Percent_Identity=23.758865248227, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786504, Length=487, Percent_Identity=39.4250513347023, Blast_Score=321, Evalue=6e-89,
Organism=Escherichia coli, GI1787558, Length=491, Percent_Identity=37.4745417515275, Blast_Score=306, Evalue=2e-84,
Organism=Escherichia coli, GI87082295, Length=486, Percent_Identity=34.5679012345679, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI87081896, Length=487, Percent_Identity=34.4969199178645, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1787715, Length=488, Percent_Identity=36.0655737704918, Blast_Score=274, Evalue=9e-75,
Organism=Escherichia coli, GI1789015, Length=483, Percent_Identity=35.6107660455487, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1787684, Length=480, Percent_Identity=32.7083333333333, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI87081926, Length=463, Percent_Identity=29.1576673866091, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1788042, Length=483, Percent_Identity=27.3291925465839, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1787250, Length=341, Percent_Identity=28.4457478005865, Blast_Score=115, Evalue=9e-27,
Organism=Escherichia coli, GI1787653, Length=463, Percent_Identity=23.3261339092873, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17551164, Length=483, Percent_Identity=38.9233954451346, Blast_Score=317, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI25144435, Length=488, Percent_Identity=36.6803278688525, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17562198, Length=483, Percent_Identity=36.6459627329193, Blast_Score=301, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI71995606, Length=483, Percent_Identity=38.0952380952381, Blast_Score=292, Evalue=3e-79,
Organism=Caenorhabditis elegans, GI25143876, Length=483, Percent_Identity=34.9896480331263, Blast_Score=283, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI25143874, Length=483, Percent_Identity=34.9896480331263, Blast_Score=282, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI133930964, Length=485, Percent_Identity=32.9896907216495, Blast_Score=270, Evalue=9e-73,
Organism=Caenorhabditis elegans, GI32564736, Length=432, Percent_Identity=36.5740740740741, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=37.5296912114014, Blast_Score=241, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI17534119, Length=476, Percent_Identity=30.0420168067227, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71986308, Length=487, Percent_Identity=29.9794661190965, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI115534176, Length=486, Percent_Identity=28.3950617283951, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI25146391, Length=342, Percent_Identity=29.2397660818713, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI32566756, Length=342, Percent_Identity=29.2397660818713, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI25146394, Length=342, Percent_Identity=29.2397660818713, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17564084, Length=346, Percent_Identity=29.1907514450867, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17534447, Length=466, Percent_Identity=25.9656652360515, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI115532534, Length=344, Percent_Identity=28.1976744186047, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32564151, Length=423, Percent_Identity=25.0591016548463, Blast_Score=104, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=24.8344370860927, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=481, Percent_Identity=36.1746361746362, Blast_Score=308, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6324950, Length=489, Percent_Identity=35.9918200408998, Blast_Score=298, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6323822, Length=486, Percent_Identity=33.5390946502058, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6323821, Length=488, Percent_Identity=32.5819672131148, Blast_Score=276, Evalue=7e-75,
Organism=Saccharomyces cerevisiae, GI6325196, Length=488, Percent_Identity=31.9672131147541, Blast_Score=258, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6319478, Length=479, Percent_Identity=31.5240083507307, Blast_Score=237, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6321828, Length=353, Percent_Identity=29.1784702549575, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6323757, Length=311, Percent_Identity=25.7234726688103, Blast_Score=93, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321826, Length=513, Percent_Identity=22.4171539961014, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129399, Length=484, Percent_Identity=36.9834710743802, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI24650465, Length=483, Percent_Identity=36.231884057971, Blast_Score=291, Evalue=1e-78,
Organism=Drosophila melanogaster, GI24585660, Length=483, Percent_Identity=32.2981366459627, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI281362580, Length=485, Percent_Identity=34.2268041237113, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI62472918, Length=485, Percent_Identity=34.2268041237113, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI62472926, Length=485, Percent_Identity=34.2268041237113, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI62472936, Length=485, Percent_Identity=34.2268041237113, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI21356737, Length=485, Percent_Identity=34.2268041237113, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24638878, Length=487, Percent_Identity=26.0780287474333, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24638876, Length=487, Percent_Identity=26.0780287474333, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24666674, Length=350, Percent_Identity=30.8571428571429, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281360299, Length=343, Percent_Identity=27.9883381924198, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360297, Length=343, Percent_Identity=27.9883381924198, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360295, Length=343, Percent_Identity=27.9883381924198, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24586250, Length=343, Percent_Identity=27.9883381924198, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360301, Length=343, Percent_Identity=27.9883381924198, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281360303, Length=343, Percent_Identity=27.4052478134111, Blast_Score=119, Evalue=6e-27,
Organism=Drosophila melanogaster, GI45552499, Length=343, Percent_Identity=27.4052478134111, Blast_Score=119, Evalue=7e-27,
Organism=Drosophila melanogaster, GI24668425, Length=352, Percent_Identity=25.8522727272727, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24668417, Length=352, Percent_Identity=25.8522727272727, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24668413, Length=352, Percent_Identity=25.8522727272727, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360293, Length=157, Percent_Identity=33.7579617834395, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574525, Length=477, Percent_Identity=25.3668763102725, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28571798, Length=494, Percent_Identity=22.0647773279352, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571796, Length=494, Percent_Identity=22.0647773279352, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571794, Length=494, Percent_Identity=22.0647773279352, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571806, Length=494, Percent_Identity=22.0647773279352, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571802, Length=494, Percent_Identity=22.0647773279352, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28571800, Length=494, Percent_Identity=22.0647773279352, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017628 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: 1.2.1.60

Molecular weight: Translated: 52322; Mature: 52322

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIENFIAGEYVAAASGRRFEKRSPVDNRVIASISEAGRPEVDAAVQAARAALHGEWGG
CCHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
LTADQRVELLYGVANEITRRFEDFVEAETADTGQPSHVMRHVFIPRGAANFKVFADVVKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
VPTEAFQMATPDGAGALNYAIRVPKGVIGVICPWNAPFLLMTWKLGPALACGNTVVVKPS
CCHHHHEECCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEECCCEEEEECC
EETPNTAALLGEVMNAVGVPKGVYNVVNGFGPDSAGAFLTQHPGVDAITFTGETRTGAAI
CCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCCHHHH
MKAASEGMRDVSFELGGKNAGIVFADADFDAAVDGIFRSAFLNTGQVCLGTERVYVERPI
HHHHHHCCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEECCCEEEEECHH
FERFVQALKLKAEAVKYGRPEDHTANYGPLISQEHKRKVLSYYAKAVEEGATVVTGGGVP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCC
DMPGELAEGAWVQPTIWTGLPETAAVVREEIFGPCCHIRPFDSEQEVVALANATDYGLST
CCCHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEE
TIWTTNLARAHRVAARVEVGITWINSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTETR
EEEEHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCC
NVCVKL
CEEEEC
>Mature Secondary Structure
MRQIENFIAGEYVAAASGRRFEKRSPVDNRVIASISEAGRPEVDAAVQAARAALHGEWGG
CCHHHHHHHCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
LTADQRVELLYGVANEITRRFEDFVEAETADTGQPSHVMRHVFIPRGAANFKVFADVVKN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
VPTEAFQMATPDGAGALNYAIRVPKGVIGVICPWNAPFLLMTWKLGPALACGNTVVVKPS
CCHHHHEECCCCCCCCEEEEEECCCCCEEEEECCCCCEEEEEECCCCEEECCCEEEEECC
EETPNTAALLGEVMNAVGVPKGVYNVVNGFGPDSAGAFLTQHPGVDAITFTGETRTGAAI
CCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCEEECCCCCCEEEECCCCCCHHHH
MKAASEGMRDVSFELGGKNAGIVFADADFDAAVDGIFRSAFLNTGQVCLGTERVYVERPI
HHHHHHCCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHCCCCEEECCCEEEEECHH
FERFVQALKLKAEAVKYGRPEDHTANYGPLISQEHKRKVLSYYAKAVEEGATVVTGGGVP
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCC
DMPGELAEGAWVQPTIWTGLPETAAVVREEIFGPCCHIRPFDSEQEVVALANATDYGLST
CCCHHHCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEE
TIWTTNLARAHRVAARVEVGITWINSWFLRDLRTAFGGSKQSGIGREGGVHSLEFYTETR
EEEEHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCC
NVCVKL
CEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-carboxymethyl-2-hydroxymuconate semialdehyde; H2O; NAD+

Specific reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]