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The map label for this gene is mcp4 [H]

Identifier: 119898132

GI number: 119898132

Start: 2022415

End: 2023890

Strand: Direct

Name: mcp4 [H]

Synonym: azo1841

Alternate gene names: 119898132

Gene position: 2022415-2023890 (Clockwise)

Preceding gene: 119898131

Following gene: 119898133

Centisome position: 46.22

GC content: 73.64

Gene sequence:

>1476_bases
GTGACGGGCGGAACGGGCGGCCGCGCGGCGCAGGCGTCGCTGTTGCTGGCCGGGTTGACGGTGACCGGCCTGGGCGGCGC
CGTGGGTGGCAGCGCGGGCTGGACGGCAGTCGCGGTCGGCGTCGTCTGCGCGCTGGCGGCGCTGTGGATGGCCTGGAACG
CGCATCGGCGGGTGGGCGGGGCGGTGGATGCGATCCGCGCGCTGCTGGAAGACCCGCAGGCGATTGCCGATCCGGCCGCC
TCGGTGGCCCGCCTGAACGAACTGCTGGCGGACAAGGTGGGCTACGCCACCCGCATGGGCGGGCTGGCACGCGAACTCGC
CGCCTTCAGCGGCAGCCAGGTGTCGACCTTCACGGAGGTGGTGGACGCCACCGACCGCCAGGCCGCGTTGGCGCGCGAGG
CGGTCGGCAGCGTGGTGGCGATGGCGGGCGCGGCCGACGACGTGGCGGCGGGCGCGGCGCATCTGGTGGGCCTCGCCACC
CAGGTCAGCAGCCATGCGGCCAACGGCGGCGAGCGGGTGGCGCGGGTGGCAGCCGGGGTGAAGGAACTCGCCGAGGTGAT
CGCCGGTGTCGGCCGCGAGTTCGACGGCCTGCGCGGCCAGGTGGCGCGCATCGGCGAGATCGTCCGCATCATCCAGGAGA
TCGCCGGGCAGACCAATCTGCTCGCCTTGAATGCCGCCATCGAGGCGGCCCGCGCCGGCGAGCAGGGGCGCGGCTTCGCG
GTGGTGGCGGACGAGGTGCGCAAGCTCGCCGAACGCACTGCGACCGCGACAGTGAGCGTGGACGAGATCATCGACGGCAT
CGGCCGCGGTTTCGACCATCTCAAGCACGGCATCGACGCGGTGACCGGCATGGCGCACGACGGCGTCGCCCGCAGCGGCG
AGGCGATGGCGACGCTGGAAGGCATCGCCGCCGCCGCGCGCGACAGTGAAAGCGCGGTGGCCGAGATCGCCGCGCGCGCC
ACCGCCGGGGCGCAGACCGGCGGCGCGGTGGTGGAGGCGATGACCGGCGTCGACACGCTGGCGCGCATGCTCGACGACCG
CATCAACCTCTGCAACGACGGCCTGCGCGGGCTGATGCTCAAGCTGGTCGACATGAAGGCGCTGGCCGGGCGGCTGGAGG
TGCAGCACGACGCGCTCGGCGCGGTGCTCGACGCGATCGAGGAAACCCGGGTGAACAACATCATGGTGCTCAATGCCCGC
ACGACCGCGCAGGCGCTGCCGCATATCGAACGCATCGAAGCGCTCGACCGCGAGATGGACATCCAGCTCGCCCGACTGGA
TGCGGCGGCCTTGGCGCTGCCGCTGCGCACGCTGCGCGACAGGCTGGCCGCCTACCGCCGGGTGCGCGACGACGCGCTCG
CTCATGCCCGCAGCGGCGATCTGGAGCAAACGCGCAAGCTGGCGCCGGCCCAGGTGCGGCCCGCTTACCAGGCGGTGAAG
GAGGCCTATGCCGCGCTCGCCGCGGCCGCCGCGTGA

Upstream 100 bases:

>100_bases
AGCGGGCTGCAGCGGCTGATGCTCGGCTCGGTAACGGCGCGGCTGCTGGCGGAAGCCCGGCTGCCGGTGCTGGTCGCCCG
CGTTGCACAGGACTAGCGCC

Downstream 100 bases:

>100_bases
TCCCGAAAGACCGTGGCGGGCAGCGCGAGGCTATTACGATCGCGGTAAAGTGCGAGGCCTATGGAAGAACACGGTCAGGC
CCCCGGCAGAGGGGCGCGAC

Product: methyl-accepting chemotaxis transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MTGGTGGRAAQASLLLAGLTVTGLGGAVGGSAGWTAVAVGVVCALAALWMAWNAHRRVGGAVDAIRALLEDPQAIADPAA
SVARLNELLADKVGYATRMGGLARELAAFSGSQVSTFTEVVDATDRQAALAREAVGSVVAMAGAADDVAAGAAHLVGLAT
QVSSHAANGGERVARVAAGVKELAEVIAGVGREFDGLRGQVARIGEIVRIIQEIAGQTNLLALNAAIEAARAGEQGRGFA
VVADEVRKLAERTATATVSVDEIIDGIGRGFDHLKHGIDAVTGMAHDGVARSGEAMATLEGIAAAARDSESAVAEIAARA
TAGAQTGGAVVEAMTGVDTLARMLDDRINLCNDGLRGLMLKLVDMKALAGRLEVQHDALGAVLDAIEETRVNNIMVLNAR
TTAQALPHIERIEALDREMDIQLARLDAAALALPLRTLRDRLAAYRRVRDDALAHARSGDLEQTRKLAPAQVRPAYQAVK
EAYAALAAAAA

Sequences:

>Translated_491_residues
MTGGTGGRAAQASLLLAGLTVTGLGGAVGGSAGWTAVAVGVVCALAALWMAWNAHRRVGGAVDAIRALLEDPQAIADPAA
SVARLNELLADKVGYATRMGGLARELAAFSGSQVSTFTEVVDATDRQAALAREAVGSVVAMAGAADDVAAGAAHLVGLAT
QVSSHAANGGERVARVAAGVKELAEVIAGVGREFDGLRGQVARIGEIVRIIQEIAGQTNLLALNAAIEAARAGEQGRGFA
VVADEVRKLAERTATATVSVDEIIDGIGRGFDHLKHGIDAVTGMAHDGVARSGEAMATLEGIAAAARDSESAVAEIAARA
TAGAQTGGAVVEAMTGVDTLARMLDDRINLCNDGLRGLMLKLVDMKALAGRLEVQHDALGAVLDAIEETRVNNIMVLNAR
TTAQALPHIERIEALDREMDIQLARLDAAALALPLRTLRDRLAAYRRVRDDALAHARSGDLEQTRKLAPAQVRPAYQAVK
EAYAALAAAAA
>Mature_490_residues
TGGTGGRAAQASLLLAGLTVTGLGGAVGGSAGWTAVAVGVVCALAALWMAWNAHRRVGGAVDAIRALLEDPQAIADPAAS
VARLNELLADKVGYATRMGGLARELAAFSGSQVSTFTEVVDATDRQAALAREAVGSVVAMAGAADDVAAGAAHLVGLATQ
VSSHAANGGERVARVAAGVKELAEVIAGVGREFDGLRGQVARIGEIVRIIQEIAGQTNLLALNAAIEAARAGEQGRGFAV
VADEVRKLAERTATATVSVDEIIDGIGRGFDHLKHGIDAVTGMAHDGVARSGEAMATLEGIAAAARDSESAVAEIAARAT
AGAQTGGAVVEAMTGVDTLARMLDDRINLCNDGLRGLMLKLVDMKALAGRLEVQHDALGAVLDAIEETRVNNIMVLNART
TAQALPHIERIEALDREMDIQLARLDAAALALPLRTLRDRLAAYRRVRDDALAHARSGDLEQTRKLAPAQVRPAYQAVKE
AYAALAAAAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=285, Percent_Identity=31.2280701754386, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1787690, Length=176, Percent_Identity=36.3636363636364, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788195, Length=201, Percent_Identity=35.8208955223881, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI2367378, Length=259, Percent_Identity=32.4324324324324, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788194, Length=63, Percent_Identity=63.4920634920635, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 50351; Mature: 50220

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGTGGRAAQASLLLAGLTVTGLGGAVGGSAGWTAVAVGVVCALAALWMAWNAHRRVGG
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDAIRALLEDPQAIADPAASVARLNELLADKVGYATRMGGLARELAAFSGSQVSTFTEV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDATDRQAALAREAVGSVVAMAGAADDVAAGAAHLVGLATQVSSHAANGGERVARVAAGV
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KELAEVIAGVGREFDGLRGQVARIGEIVRIIQEIAGQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEE
VVADEVRKLAERTATATVSVDEIIDGIGRGFDHLKHGIDAVTGMAHDGVARSGEAMATLE
EHHHHHHHHHHHHHHHEEEHHHHHHHHHCCHHHHHHHHHHHHCCHHCCCCCCCCHHHHHH
GIAAAARDSESAVAEIAARATAGAQTGGAVVEAMTGVDTLARMLDDRINLCNDGLRGLML
HHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLVDMKALAGRLEVQHDALGAVLDAIEETRVNNIMVLNARTTAQALPHIERIEALDREMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCHHHHHHHHHHHHH
IQLARLDAAALALPLRTLRDRLAAYRRVRDDALAHARSGDLEQTRKLAPAQVRPAYQAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHCCHHHHHHH
EAYAALAAAAA
HHHHHHHHHCC
>Mature Secondary Structure 
TGGTGGRAAQASLLLAGLTVTGLGGAVGGSAGWTAVAVGVVCALAALWMAWNAHRRVGG
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVDAIRALLEDPQAIADPAASVARLNELLADKVGYATRMGGLARELAAFSGSQVSTFTEV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDATDRQAALAREAVGSVVAMAGAADDVAAGAAHLVGLATQVSSHAANGGERVARVAAGV
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KELAEVIAGVGREFDGLRGQVARIGEIVRIIQEIAGQTNLLALNAAIEAARAGEQGRGFA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCCCEE
VVADEVRKLAERTATATVSVDEIIDGIGRGFDHLKHGIDAVTGMAHDGVARSGEAMATLE
EHHHHHHHHHHHHHHHEEEHHHHHHHHHCCHHHHHHHHHHHHCCHHCCCCCCCCHHHHHH
GIAAAARDSESAVAEIAARATAGAQTGGAVVEAMTGVDTLARMLDDRINLCNDGLRGLML
HHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLVDMKALAGRLEVQHDALGAVLDAIEETRVNNIMVLNARTTAQALPHIERIEALDREMD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCHHHHHHHHHHHHH
IQLARLDAAALALPLRTLRDRLAAYRRVRDDALAHARSGDLEQTRKLAPAQVRPAYQAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHCCHHHHHHH
EAYAALAAAAA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]