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The map label for this gene is mshA2 [H]

Identifier: 119898100

GI number: 119898100

Start: 1986153

End: 1987412

Strand: Reverse

Name: mshA2 [H]

Synonym: azo1809

Alternate gene names: 119898100

Gene position: 1987412-1986153 (Counterclockwise)

Preceding gene: 119898102

Following gene: 119898099

Centisome position: 45.42

GC content: 70.71

Gene sequence:

>1260_bases
ATGAATATTGCATTGATCAGCGAACACGCGTCGCCCCTCGCCGTTCAAGGGGGAACGGACAGTGGCGGGCAGAACGTGTA
TGTCGCCTACGTCGCCCGCGAACTCGGCCGCGCCGGCCATACCGTCGATGTGTTCACCCGCCGCGACGACCCCGCGCTGC
CGGCGGTCATCGACTTCGCCCCCAACGTGCGCGTGATGCCGGTACCCGCCGGACCGCCGCACTTCGTCCCCAAGGAACAG
CTGCTGCCCTACATGAGCGCCTTCGGCGACGGCATCGCCGCGCGCTGCCTGGCGCCGGGGCGGCCCTACGACATCGTGCA
CGCCAACTTCTTCATGTCCGGGCTGGTGGGCATGCGCCTGCGCGAGGACTTCGGCCTGCCGCTGGTGGTCACCTTCCACG
CGCTCGGCAAGGTGCGCCGTCGCCATCAGGGCAGCGCCGACGGCTTTCCTGAGGAGCGGCTGCAGATCGAGGAGGCCCTC
GTCGCCAGTGCCGACCGCATCATCGCCGAGTGCCCGCAGGACCGCGACGACCTGATCCGCCTGTACGGCGCCGAGCGCGA
GCGCATCGACATCGTGCCCTGCGGGGTGGATACCGCCGAGCTGGGCCCGAGCGAAGGCGCGCGCGCCCGGCTGGGGCTGG
CCGAGGACGAGTTCGTGGTACTGCAGCTCGGCCGCATGGTGCCGCGCAAGGGCATCGACAATGTGATCCGCGCGGTGGGC
GAACTGCGCCGCCGGCACGGCGTGGCCGCGCGCCTGCTGGTGGTGGGCGGCGAAACAGCGGAACCCGATCCGCTGCGCAC
GCCGGAAATCGGCCGCCTGCAGCAGATCGCCGAGGACGAAGGGGTGAGCGCGCAGGTGGTGTTCACCGGGCGCCGCGAAC
GGCACTGCCTGCGCGACTACTACTGCGCCGCCGACGTCTTCGTGACCACCCCCTGGTACGAGCCCTTCGGCATCACCCCG
CTGGAGGCCATGGCCTGCGGCTGCCCGGTCATCGGCGCCGCGGTCGGCGGCATCCGCCACACCGTGGTCAATGGCACCAC
CGGCTTCCTGGTGCCGCCGCACGACCCGGTGCAACTGGCCGACCGCCTCGCCCGCCTGCAGGCCGACCCGGAGCGGGCAC
GCACCTTCGGACGCGCCGGCATCCGCCGCGTCCGCAGCAAATTCACTTGGCAGCGCGTTGCCGCCTCGCTTGCGTCGGTG
TACGGCGCGCTGCACCAACCGCGTGCAGTCCAACTTACGGAAAGGATGATGGGCCTATGA

Upstream 100 bases:

>100_bases
TGCGCAAAAAAGCAGCAGCGCCATCGCGACCCGCCCCCCCAATCCGGGCACAGCGTTTGCCGAAGCAGCGATCACCCATT
CCTGCGACATAGGCGCTCCC

Downstream 100 bases:

>100_bases
GAACAACATCGACGATACCGCTCGACAACAAGACCGCCCTCGTGACGGGGGGCGCCCGCGGCCTTGGCAAGGCCTTGTGC
GAGGCCTTGTGCGAAGCCGG

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase 2; GlcNAc-Ins-P N-acetylglucosaminyltransferase 2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MNIALISEHASPLAVQGGTDSGGQNVYVAYVARELGRAGHTVDVFTRRDDPALPAVIDFAPNVRVMPVPAGPPHFVPKEQ
LLPYMSAFGDGIAARCLAPGRPYDIVHANFFMSGLVGMRLREDFGLPLVVTFHALGKVRRRHQGSADGFPEERLQIEEAL
VASADRIIAECPQDRDDLIRLYGAERERIDIVPCGVDTAELGPSEGARARLGLAEDEFVVLQLGRMVPRKGIDNVIRAVG
ELRRRHGVAARLLVVGGETAEPDPLRTPEIGRLQQIAEDEGVSAQVVFTGRRERHCLRDYYCAADVFVTTPWYEPFGITP
LEAMACGCPVIGAAVGGIRHTVVNGTTGFLVPPHDPVQLADRLARLQADPERARTFGRAGIRRVRSKFTWQRVAASLASV
YGALHQPRAVQLTERMMGL

Sequences:

>Translated_419_residues
MNIALISEHASPLAVQGGTDSGGQNVYVAYVARELGRAGHTVDVFTRRDDPALPAVIDFAPNVRVMPVPAGPPHFVPKEQ
LLPYMSAFGDGIAARCLAPGRPYDIVHANFFMSGLVGMRLREDFGLPLVVTFHALGKVRRRHQGSADGFPEERLQIEEAL
VASADRIIAECPQDRDDLIRLYGAERERIDIVPCGVDTAELGPSEGARARLGLAEDEFVVLQLGRMVPRKGIDNVIRAVG
ELRRRHGVAARLLVVGGETAEPDPLRTPEIGRLQQIAEDEGVSAQVVFTGRRERHCLRDYYCAADVFVTTPWYEPFGITP
LEAMACGCPVIGAAVGGIRHTVVNGTTGFLVPPHDPVQLADRLARLQADPERARTFGRAGIRRVRSKFTWQRVAASLASV
YGALHQPRAVQLTERMMGL
>Mature_419_residues
MNIALISEHASPLAVQGGTDSGGQNVYVAYVARELGRAGHTVDVFTRRDDPALPAVIDFAPNVRVMPVPAGPPHFVPKEQ
LLPYMSAFGDGIAARCLAPGRPYDIVHANFFMSGLVGMRLREDFGLPLVVTFHALGKVRRRHQGSADGFPEERLQIEEAL
VASADRIIAECPQDRDDLIRLYGAERERIDIVPCGVDTAELGPSEGARARLGLAEDEFVVLQLGRMVPRKGIDNVIRAVG
ELRRRHGVAARLLVVGGETAEPDPLRTPEIGRLQQIAEDEGVSAQVVFTGRRERHCLRDYYCAADVFVTTPWYEPFGITP
LEAMACGCPVIGAAVGGIRHTVVNGTTGFLVPPHDPVQLADRLARLQADPERARTFGRAGIRRVRSKFTWQRVAASLASV
YGALHQPRAVQLTERMMGL

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI14861836, Length=180, Percent_Identity=30, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1790061, Length=197, Percent_Identity=28.9340101522843, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 45708; Mature: 45708

Theoretical pI: Translated: 7.31; Mature: 7.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIALISEHASPLAVQGGTDSGGQNVYVAYVARELGRAGHTVDVFTRRDDPALPAVIDFA
CCEEEEECCCCCEEEECCCCCCCCEEEEEHHHHHHCCCCCEEEEEECCCCCCCCEEEECC
PNVRVMPVPAGPPHFVPKEQLLPYMSAFGDGIAARCLAPGRPYDIVHANFFMSGLVGMRL
CCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEHHHHHHHHHHHHH
REDFGLPLVVTFHALGKVRRRHQGSADGFPEERLQIEEALVASADRIIAECPQDRDDLIR
HHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LYGAERERIDIVPCGVDTAELGPSEGARARLGLAEDEFVVLQLGRMVPRKGIDNVIRAVG
HHCCCCCEEEEEECCCCHHHCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHH
ELRRRHGVAARLLVVGGETAEPDPLRTPEIGRLQQIAEDEGVSAQVVFTGRRERHCLRDY
HHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
YCAADVFVTTPWYEPFGITPLEAMACGCPVIGAAVGGIRHTVVNGTTGFLVPPHDPVQLA
HHHCCEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHEEECCCCCEEECCCCHHHHH
DRLARLQADPERARTFGRAGIRRVRSKFTWQRVAASLASVYGALHQPRAVQLTERMMGL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNIALISEHASPLAVQGGTDSGGQNVYVAYVARELGRAGHTVDVFTRRDDPALPAVIDFA
CCEEEEECCCCCEEEECCCCCCCCEEEEEHHHHHHCCCCCEEEEEECCCCCCCCEEEECC
PNVRVMPVPAGPPHFVPKEQLLPYMSAFGDGIAARCLAPGRPYDIVHANFFMSGLVGMRL
CCCEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEHHHHHHHHHHHHH
REDFGLPLVVTFHALGKVRRRHQGSADGFPEERLQIEEALVASADRIIAECPQDRDDLIR
HHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LYGAERERIDIVPCGVDTAELGPSEGARARLGLAEDEFVVLQLGRMVPRKGIDNVIRAVG
HHCCCCCEEEEEECCCCHHHCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHH
ELRRRHGVAARLLVVGGETAEPDPLRTPEIGRLQQIAEDEGVSAQVVFTGRRERHCLRDY
HHHHHCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
YCAADVFVTTPWYEPFGITPLEAMACGCPVIGAAVGGIRHTVVNGTTGFLVPPHDPVQLA
HHHCCEEEECCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHEEECCCCCEEECCCCHHHHH
DRLARLQADPERARTFGRAGIRRVRSKFTWQRVAASLASVYGALHQPRAVQLTERMMGL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA