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The map label for this gene is qoxA [H]

Identifier: 119898048

GI number: 119898048

Start: 1922679

End: 1925261

Strand: Direct

Name: qoxA [H]

Synonym: azo1757

Alternate gene names: 119898048

Gene position: 1922679-1925261 (Clockwise)

Preceding gene: 119898047

Following gene: 119898049

Centisome position: 43.94

GC content: 70.65

Gene sequence:

>2583_bases
GTGAGCACCGAGCCGCTTCCGGCGGCCGGCGCCGGCCCGGCCTCTGCCGCCGACGCGGTGGCCGAGGCCGAACGCCTGCA
CGACGCCTTCAACGCGGTATGGGGCAACCCCGGCGGCTGGCGCGCGCTCACCATCGTCAATCACACCACCGTGGGCTTGC
GCTTCCTGCTGACCGGGCTCGGCTTCTTCGTGGTCGGCGGCATCCTCGCGATGCTGGTGCGCAGCCAGCTTGCGCTGCCC
GGCCATACCTTCATGACGCCCGAGGTGTATGCGCAGGTGTTCACCATGCACGGCACGGTGATGATGTTCCTGTTCGCGGT
GCCGATGATGGAGGGCCTGGCGGTCTACCTGCTGCCCAAGATGCTGGGTGCGCGCGACCTGGTGTTTCCGCGCCTGTCCG
CGCTCGGCTACTGGTGTTACCTGTTCGGCGGGCTGATCCTGGTCTCCAGCCTCTTTCTCGGCCTCGCGCCGGATGCGGGC
TGGTTCATGTACGTGCCGCTGGCCGGCAGCACCTACACGCCGGGCCCGAATTCGGACTTCTGGCTGCTCGGCATCACCTT
CGTCGAAATCTCCGCGGTATCGGCCGGGGTGGAGCTGGCGGTGTCCATCCTGCGTGCCCGCGCGCCCGGCATGTCGCTGG
AGAAGATGCCGCTCTACGCCTGGTACATCCTGGTGATGGCGCTGATGATCGTGGTCGGCTTTCCGCCGCTGATCCTCGGC
AGCATCCTGCTGGAACTGGAACGCGCCGCCGGCATGCCCTTCTTCGAGGTCGCGCGCGGTGGCGACCCGGTGCTGTGGCA
GCACCTGTTCTGGCTGTTCGGCCATCCGGAGGTGTACATCATCTTCCTGCCGGCGGCGGGCATCGTGTCCACGCTGCTGC
CGGTGTTCGCGCGGCGACCGGCGGTGGGGCACGCCTGGGTGGTGGTCGCGGTGGTCAGCACCGGCTTCATCAGCTTCGGG
CTGTGGGTGCACCACATGTTCACCGTCGGCATCCCGCAGCTCGCGCAGGCCTTCTTTTCGGCCGCCAGCATGCTGGTGGC
GGTGCCCACCGGCGTGCAGGTGTTCTCGTGGATCGCCACGCTGTGGCTGGGGCGGCCGGTGTTCCACGTGCCCATGCTGT
GGCTCACTGGCTTTCTGGTCATCTTCGTCGCCGGCGGGCTCACCGGCGTGATGCTGGCGCTGGTGCCCTTCGACTGGCAG
GTGCACGACAGCCAGTTCGTGGTCGCCCACCTGCATTACGTGCTGGTGGGCGGCATGCTGTTTCCGCTGGTGGCGGGGCT
GTATTACTGGCTGCCGCATTTCTCCGGCCGGCTGCCGTCGGCGGCGCTCGGGCGCACCGGCTTCTGGCTGGTGTTCATCG
GCTTCAACCTCACCTTCCTGGTGATGCACTGGACGGGCCTGCTGGGCATGCCGCGCCGGGTGCACACCTACGAAACCGGG
CTGGGCTGGGACGGCCCCAATCTGCTGTCGTCGATCGGCAGCTTCGTGATGGCGGCCGGCATCGTCGCGGTGCTGTGCGA
CATCGTGCTGCACTTCCGCTACGGTGCGCGCGCGCGGCCCAATCCGTGGAATGCGGGCACCCTGGAGTGGGCCACCGCGA
CCCCGCCCAGCCCGTACAACTTCGTCAGCCTGCCGGCGGTGCAGGACCGCCACCCGCTGTGGTCCAACCCCGGCCTGGGC
GACGACCTTGCCCGCGGCCACGGCGGGCTGGCGCTGATCGACCACGGCCGGCGCGAAACCTGGGGCACCGACCCGGCGAG
CGGCGCGGTGCGCGAGATCATCCACCTGCCGGGCAACAGCTGGCTGCCCTTTGCGGCCGCGCTGCTGATCGGCGGCGTCT
GCATCTGCCTGCTGCTGCGCGCCTATCCGCTGGCGGCGGCGTTTACGCTCGGGTCCCTGGCGGTGCTGCTGCGCTGGTCG
TGGGAAAACGGCACGCATCCGCTCGCCGCGCCCGACGCGCGCACCGCGCCGGGCGACCCGCCGCTGCATTCGCGCACCTT
CGACGGCCCCGGGCTGTGGGGCATGGCGCTGACGCTGCTTGCCAACGGCGCGCTCTACCTGTCGCTGCTGTTCGGCTGGC
TGTACTTGTGGACCGTGGCGCCCGCATGGCAGGCGCCGCCGCCGGACCACGGGCTTGCGGCGGGCAAGGGCGCGGGGCTG
TTGCTGGCGGCGGCGCTCGCGCTCAGCGCCGGCACGCTGGTGCTGCGCCGCGCGGTGGCGCGGCTGCGCGCCGGCATCGG
CCGCGGCCTGGGCGCGCTGCTGGCGCTGGCGGCACTGCTCGGCCTCGTCCATTGCGGGTTGCTGGCGGGCGTGTTCTCCG
CGGCCGGGCTGGCGCCAACCAAGACCGCCCACGACGCGGTCAGTGCGGTGATGCTGGGCTACGCGCTCGTCCACGGTGCG
CTCGCGGCGCTGCTGGCGGCCTTGCAGGCACTACGCGTGCGCTTTGGCTATGTCGGCATCGAAGCGCCTTACGAGCCGCT
GGTGGTGAGCCAATGGTGGCACTACAGCGCGGTGACGCTGTGGGCCAGCTACGCCGCGCTGGTGTGGTTTCCCGCCGTGT
GGGGCCTGGGAGGCGGGGCGTGA

Upstream 100 bases:

>100_bases
GCGCCGAATACTGCGGCAGCGGGCACGCAGGCATGGCGCTGGCGGTGGAGGCCCAGCCCGAAGCGGCCTTTGCCGCCTGG
CTGGCGGCGGAGGCGGGGCG

Downstream 100 bases:

>100_bases
GGCCGCCGCCCTTCCATCCGCTGCATCTCGCGCTCGGGCTGGGCTGGTGGGCGCTGTGGTTCGTGGCGCTGTACGGCGGG
CTGGCGCTGGCCTGCGCGCG

Product: quinol oxidase subunit I

Products: NA

Alternate protein names: Caa-3605 subunit 1; Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I; Oxidase aa(3) subunit 1 [H]

Number of amino acids: Translated: 860; Mature: 859

Protein sequence:

>860_residues
MSTEPLPAAGAGPASAADAVAEAERLHDAFNAVWGNPGGWRALTIVNHTTVGLRFLLTGLGFFVVGGILAMLVRSQLALP
GHTFMTPEVYAQVFTMHGTVMMFLFAVPMMEGLAVYLLPKMLGARDLVFPRLSALGYWCYLFGGLILVSSLFLGLAPDAG
WFMYVPLAGSTYTPGPNSDFWLLGITFVEISAVSAGVELAVSILRARAPGMSLEKMPLYAWYILVMALMIVVGFPPLILG
SILLELERAAGMPFFEVARGGDPVLWQHLFWLFGHPEVYIIFLPAAGIVSTLLPVFARRPAVGHAWVVVAVVSTGFISFG
LWVHHMFTVGIPQLAQAFFSAASMLVAVPTGVQVFSWIATLWLGRPVFHVPMLWLTGFLVIFVAGGLTGVMLALVPFDWQ
VHDSQFVVAHLHYVLVGGMLFPLVAGLYYWLPHFSGRLPSAALGRTGFWLVFIGFNLTFLVMHWTGLLGMPRRVHTYETG
LGWDGPNLLSSIGSFVMAAGIVAVLCDIVLHFRYGARARPNPWNAGTLEWATATPPSPYNFVSLPAVQDRHPLWSNPGLG
DDLARGHGGLALIDHGRRETWGTDPASGAVREIIHLPGNSWLPFAAALLIGGVCICLLLRAYPLAAAFTLGSLAVLLRWS
WENGTHPLAAPDARTAPGDPPLHSRTFDGPGLWGMALTLLANGALYLSLLFGWLYLWTVAPAWQAPPPDHGLAAGKGAGL
LLAAALALSAGTLVLRRAVARLRAGIGRGLGALLALAALLGLVHCGLLAGVFSAAGLAPTKTAHDAVSAVMLGYALVHGA
LAALLAALQALRVRFGYVGIEAPYEPLVVSQWWHYSAVTLWASYAALVWFPAVWGLGGGA

Sequences:

>Translated_860_residues
MSTEPLPAAGAGPASAADAVAEAERLHDAFNAVWGNPGGWRALTIVNHTTVGLRFLLTGLGFFVVGGILAMLVRSQLALP
GHTFMTPEVYAQVFTMHGTVMMFLFAVPMMEGLAVYLLPKMLGARDLVFPRLSALGYWCYLFGGLILVSSLFLGLAPDAG
WFMYVPLAGSTYTPGPNSDFWLLGITFVEISAVSAGVELAVSILRARAPGMSLEKMPLYAWYILVMALMIVVGFPPLILG
SILLELERAAGMPFFEVARGGDPVLWQHLFWLFGHPEVYIIFLPAAGIVSTLLPVFARRPAVGHAWVVVAVVSTGFISFG
LWVHHMFTVGIPQLAQAFFSAASMLVAVPTGVQVFSWIATLWLGRPVFHVPMLWLTGFLVIFVAGGLTGVMLALVPFDWQ
VHDSQFVVAHLHYVLVGGMLFPLVAGLYYWLPHFSGRLPSAALGRTGFWLVFIGFNLTFLVMHWTGLLGMPRRVHTYETG
LGWDGPNLLSSIGSFVMAAGIVAVLCDIVLHFRYGARARPNPWNAGTLEWATATPPSPYNFVSLPAVQDRHPLWSNPGLG
DDLARGHGGLALIDHGRRETWGTDPASGAVREIIHLPGNSWLPFAAALLIGGVCICLLLRAYPLAAAFTLGSLAVLLRWS
WENGTHPLAAPDARTAPGDPPLHSRTFDGPGLWGMALTLLANGALYLSLLFGWLYLWTVAPAWQAPPPDHGLAAGKGAGL
LLAAALALSAGTLVLRRAVARLRAGIGRGLGALLALAALLGLVHCGLLAGVFSAAGLAPTKTAHDAVSAVMLGYALVHGA
LAALLAALQALRVRFGYVGIEAPYEPLVVSQWWHYSAVTLWASYAALVWFPAVWGLGGGA
>Mature_859_residues
STEPLPAAGAGPASAADAVAEAERLHDAFNAVWGNPGGWRALTIVNHTTVGLRFLLTGLGFFVVGGILAMLVRSQLALPG
HTFMTPEVYAQVFTMHGTVMMFLFAVPMMEGLAVYLLPKMLGARDLVFPRLSALGYWCYLFGGLILVSSLFLGLAPDAGW
FMYVPLAGSTYTPGPNSDFWLLGITFVEISAVSAGVELAVSILRARAPGMSLEKMPLYAWYILVMALMIVVGFPPLILGS
ILLELERAAGMPFFEVARGGDPVLWQHLFWLFGHPEVYIIFLPAAGIVSTLLPVFARRPAVGHAWVVVAVVSTGFISFGL
WVHHMFTVGIPQLAQAFFSAASMLVAVPTGVQVFSWIATLWLGRPVFHVPMLWLTGFLVIFVAGGLTGVMLALVPFDWQV
HDSQFVVAHLHYVLVGGMLFPLVAGLYYWLPHFSGRLPSAALGRTGFWLVFIGFNLTFLVMHWTGLLGMPRRVHTYETGL
GWDGPNLLSSIGSFVMAAGIVAVLCDIVLHFRYGARARPNPWNAGTLEWATATPPSPYNFVSLPAVQDRHPLWSNPGLGD
DLARGHGGLALIDHGRRETWGTDPASGAVREIIHLPGNSWLPFAAALLIGGVCICLLLRAYPLAAAFTLGSLAVLLRWSW
ENGTHPLAAPDARTAPGDPPLHSRTFDGPGLWGMALTLLANGALYLSLLFGWLYLWTVAPAWQAPPPDHGLAAGKGAGLL
LAAALALSAGTLVLRRAVARLRAGIGRGLGALLALAALLGLVHCGLLAGVFSAAGLAPTKTAHDAVSAVMLGYALVHGAL
AALLAALQALRVRFGYVGIEAPYEPLVVSQWWHYSAVTLWASYAALVWFPAVWGLGGGA

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Co I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=507, Percent_Identity=36.094674556213, Blast_Score=311, Evalue=2e-84,
Organism=Escherichia coli, GI1786634, Length=568, Percent_Identity=35.0352112676056, Blast_Score=353, Evalue=2e-98,
Organism=Saccharomyces cerevisiae, GI6226519, Length=510, Percent_Identity=34.9019607843137, Blast_Score=319, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6226524, Length=298, Percent_Identity=34.5637583892617, Blast_Score=211, Evalue=5e-55,
Organism=Saccharomyces cerevisiae, GI6226523, Length=220, Percent_Identity=32.7272727272727, Blast_Score=124, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 91898; Mature: 91767

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTEPLPAAGAGPASAADAVAEAERLHDAFNAVWGNPGGWRALTIVNHTTVGLRFLLTGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
GFFVVGGILAMLVRSQLALPGHTFMTPEVYAQVFTMHGTVMMFLFAVPMMEGLAVYLLPK
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGARDLVFPRLSALGYWCYLFGGLILVSSLFLGLAPDAGWFMYVPLAGSTYTPGPNSDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCE
WLLGITFVEISAVSAGVELAVSILRARAPGMSLEKMPLYAWYILVMALMIVVGFPPLILG
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
SILLELERAAGMPFFEVARGGDPVLWQHLFWLFGHPEVYIIFLPAAGIVSTLLPVFARRP
HHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCC
AVGHAWVVVAVVSTGFISFGLWVHHMFTVGIPQLAQAFFSAASMLVAVPTGVQVFSWIAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LWLGRPVFHVPMLWLTGFLVIFVAGGLTGVMLALVPFDWQVHDSQFVVAHLHYVLVGGML
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHH
FPLVAGLYYWLPHFSGRLPSAALGRTGFWLVFIGFNLTFLVMHWTGLLGMPRRVHTYETG
HHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHEEEECC
LGWDGPNLLSSIGSFVMAAGIVAVLCDIVLHFRYGARARPNPWNAGTLEWATATPPSPYN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
FVSLPAVQDRHPLWSNPGLGDDLARGHGGLALIDHGRRETWGTDPASGAVREIIHLPGNS
EEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCC
WLPFAAALLIGGVCICLLLRAYPLAAAFTLGSLAVLLRWSWENGTHPLAAPDARTAPGDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
PLHSRTFDGPGLWGMALTLLANGALYLSLLFGWLYLWTVAPAWQAPPPDHGLAAGKGAGL
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
LLAAALALSAGTLVLRRAVARLRAGIGRGLGALLALAALLGLVHCGLLAGVFSAAGLAPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KTAHDAVSAVMLGYALVHGALAALLAALQALRVRFGYVGIEAPYEPLVVSQWWHYSAVTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCHHCCHHHHHHHH
WASYAALVWFPAVWGLGGGA
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STEPLPAAGAGPASAADAVAEAERLHDAFNAVWGNPGGWRALTIVNHTTVGLRFLLTGL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHH
GFFVVGGILAMLVRSQLALPGHTFMTPEVYAQVFTMHGTVMMFLFAVPMMEGLAVYLLPK
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLGARDLVFPRLSALGYWCYLFGGLILVSSLFLGLAPDAGWFMYVPLAGSTYTPGPNSDF
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCE
WLLGITFVEISAVSAGVELAVSILRARAPGMSLEKMPLYAWYILVMALMIVVGFPPLILG
EEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
SILLELERAAGMPFFEVARGGDPVLWQHLFWLFGHPEVYIIFLPAAGIVSTLLPVFARRP
HHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCC
AVGHAWVVVAVVSTGFISFGLWVHHMFTVGIPQLAQAFFSAASMLVAVPTGVQVFSWIAT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LWLGRPVFHVPMLWLTGFLVIFVAGGLTGVMLALVPFDWQVHDSQFVVAHLHYVLVGGML
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHH
FPLVAGLYYWLPHFSGRLPSAALGRTGFWLVFIGFNLTFLVMHWTGLLGMPRRVHTYETG
HHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEEHHHHHHHHHHHHHHHCCCCHHEEEECC
LGWDGPNLLSSIGSFVMAAGIVAVLCDIVLHFRYGARARPNPWNAGTLEWATATPPSPYN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCCCCCC
FVSLPAVQDRHPLWSNPGLGDDLARGHGGLALIDHGRRETWGTDPASGAVREIIHLPGNS
EEECCCCCCCCCCCCCCCCCCHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCCC
WLPFAAALLIGGVCICLLLRAYPLAAAFTLGSLAVLLRWSWENGTHPLAAPDARTAPGDP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCC
PLHSRTFDGPGLWGMALTLLANGALYLSLLFGWLYLWTVAPAWQAPPPDHGLAAGKGAGL
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
LLAAALALSAGTLVLRRAVARLRAGIGRGLGALLALAALLGLVHCGLLAGVFSAAGLAPT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KTAHDAVSAVMLGYALVHGALAALLAALQALRVRFGYVGIEAPYEPLVVSQWWHYSAVTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCHHCCHHHHHHHH
WASYAALVWFPAVWGLGGGA
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1847686; 9384377 [H]