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The map label for this gene is qoxB [H]

Identifier: 119898047

GI number: 119898047

Start: 1922011

End: 1922682

Strand: Direct

Name: qoxB [H]

Synonym: azo1756

Alternate gene names: 119898047

Gene position: 1922011-1922682 (Clockwise)

Preceding gene: 119898045

Following gene: 119898048

Centisome position: 43.92

GC content: 74.26

Gene sequence:

>672_bases
ATGCTCGTTCCCGTGCTTGCCGGCTGCACCGGCGTGCAGTCCGCGCTGGAGCCGGCGGGGCCGGCGGCATACGAGGCCGC
GCGGCTGTGGTGGGGGATGCTGATCGTCGCCACCGTGGTGCTGGTGGGCGTGGTCGGGCTGTGGCTGCACGCGCTGCGGC
GCAGCCCTGCATCCGCCCTGGACCCCGCGCACGAGCGGCGCATCGCACGACGCTGGCTGATACTGGGGGGCCTGCTGCTG
CCGGGCGTCAGCATCGCGGCGCTGCTCGCGTTTGGCGTGCCGGCCGGTCAGCGCATGTTGCTCGCGGGCGAGGCCGGCGC
GCCCGCGCTGCGCATCGAGGTGACCGGCCGCCAATGGGGCTGGGACGTGCATTACCCCGAAGCCGGAGTGCGCCTGCGCG
ACCGCCTGCAGCTGCCGGTGGGCCGTACCGTTGAGCTGCAACTGCGCAGCGAGGACGTCATCCACTCCTTCTGGGTGCCG
CGGCTGGCCGGCAAGCTGGACCTGATCCCCGGGCGCACCAATGTGCTGCGCCTGCGCGCCGATGAGCCGGGCGTGTTCCG
CGGCCAGTGCGCCGAATACTGCGGCAGCGGGCACGCAGGCATGGCGCTGGCGGTGGAGGCCCAGCCCGAAGCGGCCTTTG
CCGCCTGGCTGGCGGCGGAGGCGGGGCGGTGA

Upstream 100 bases:

>100_bases
TAGGCGGTGCGGCGGCTGCGGGCGGGGCGGCTTCGGCGGGATCGGGCATCGCGGTCTCCTGGGCGGGCGCTGGGGCGCGC
GTTTGCAGGGGGGCCTCGCA

Downstream 100 bases:

>100_bases
GCACCGAGCCGCTTCCGGCGGCCGGCGCCGGCCCGGCCTCTGCCGCCGACGCGGTGGCCGAGGCCGAACGCCTGCACGAC
GCCTTCAACGCGGTATGGGG

Product: quniol oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MLVPVLAGCTGVQSALEPAGPAAYEAARLWWGMLIVATVVLVGVVGLWLHALRRSPASALDPAHERRIARRWLILGGLLL
PGVSIAALLAFGVPAGQRMLLAGEAGAPALRIEVTGRQWGWDVHYPEAGVRLRDRLQLPVGRTVELQLRSEDVIHSFWVP
RLAGKLDLIPGRTNVLRLRADEPGVFRGQCAEYCGSGHAGMALAVEAQPEAAFAAWLAAEAGR

Sequences:

>Translated_223_residues
MLVPVLAGCTGVQSALEPAGPAAYEAARLWWGMLIVATVVLVGVVGLWLHALRRSPASALDPAHERRIARRWLILGGLLL
PGVSIAALLAFGVPAGQRMLLAGEAGAPALRIEVTGRQWGWDVHYPEAGVRLRDRLQLPVGRTVELQLRSEDVIHSFWVP
RLAGKLDLIPGRTNVLRLRADEPGVFRGQCAEYCGSGHAGMALAVEAQPEAAFAAWLAAEAGR
>Mature_223_residues
MLVPVLAGCTGVQSALEPAGPAAYEAARLWWGMLIVATVVLVGVVGLWLHALRRSPASALDPAHERRIARRWLILGGLLL
PGVSIAALLAFGVPAGQRMLLAGEAGAPALRIEVTGRQWGWDVHYPEAGVRLRDRLQLPVGRTVELQLRSEDVIHSFWVP
RLAGKLDLIPGRTNVLRLRADEPGVFRGQCAEYCGSGHAGMALAVEAQPEAAFAAWLAAEAGR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=156, Percent_Identity=32.0512820512821, Blast_Score=91, Evalue=6e-19,
Organism=Escherichia coli, GI1786635, Length=110, Percent_Identity=35.4545454545455, Blast_Score=81, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6226540, Length=212, Percent_Identity=27.3584905660377, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 23849; Mature: 23849

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVPVLAGCTGVQSALEPAGPAAYEAARLWWGMLIVATVVLVGVVGLWLHALRRSPASAL
CCCCEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPAHERRIARRWLILGGLLLPGVSIAALLAFGVPAGQRMLLAGEAGAPALRIEVTGRQWG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCC
WDVHYPEAGVRLRDRLQLPVGRTVELQLRSEDVIHSFWVPRLAGKLDLIPGRTNVLRLRA
CCCCCCCCCCEEHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCEEEEEC
DEPGVFRGQCAEYCGSGHAGMALAVEAQPEAAFAAWLAAEAGR
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MLVPVLAGCTGVQSALEPAGPAAYEAARLWWGMLIVATVVLVGVVGLWLHALRRSPASAL
CCCCEECCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
DPAHERRIARRWLILGGLLLPGVSIAALLAFGVPAGQRMLLAGEAGAPALRIEVTGRQWG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCC
WDVHYPEAGVRLRDRLQLPVGRTVELQLRSEDVIHSFWVPRLAGKLDLIPGRTNVLRLRA
CCCCCCCCCCEEHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCEEEEEC
DEPGVFRGQCAEYCGSGHAGMALAVEAQPEAAFAAWLAAEAGR
CCCCCCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]