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The map label for this gene is ompR [H]

Identifier: 119898000

GI number: 119898000

Start: 1875852

End: 1876598

Strand: Reverse

Name: ompR [H]

Synonym: azo1709

Alternate gene names: 119898000

Gene position: 1876598-1875852 (Counterclockwise)

Preceding gene: 119898005

Following gene: 119897999

Centisome position: 42.88

GC content: 63.72

Gene sequence:

>747_bases
ATGCGCGCCATGAATACCAAGACACGATGCCGGGTTCTCCTCGTCGACGACGATGCCCGTCTGCGCGAGCTGCTGTCCCG
CTACCTCCAGGAACAAGGGTTTGCCGTCAAGGCCGTGGTCGACGCACCGATGATGGATCGCGCGCTGCATCGCGAGCACT
TCGACCTGATCGTGCTCGACCTGATGCTGCCAGGAGAAGATGGCCTGGCCATCTGCCGGCGCCTTCGCGGGGCGGAAAAC
CATATCCCGATCATCATGCTCACGGCCAAGGGCGACGACGTGGATCGCATCGTCGGCCTCGAGATGGGTGCGGACGACTA
TCTTCCCAAGCCCTTCAATCCGCGCGAACTCGTTGCTCGCATCCAGGCCGTGATGCGACGCCAGCCGCATTCGCTGCCGG
GAGCGCCGACGCCCGAAGACGAGATCGTGGTGTTCGGACGTGTGCGGGTCAATCTCGGCACCCGTGCGCTCACCCGGGAC
GGCGAGGAAATCCAGCTCACCACCGGCGAATTCTCGCTGCTCAAGGTGCTGCTGCAGCATCCGCGTCAGCCGCTCTCGCG
CGACAAGCTGATGGAACTGGCTCGGGGCCGCGAATATGGGGTGTTCGACCGCGCCATCGACGTCCAGGTGTCACGCCTGC
GCAAGCTTGTGGAAGACGACCCGGCCAAGCCCCGCTACATCCAGACTGTGTGGGGATTCGGCTATGTTTTCGTACCGGAC
GACAACAAACCCGCCGAGGCTGAGTGA

Upstream 100 bases:

>100_bases
AGGGCTTATTGCCCAAAACCACCTATTTACGAAGCGTTACCCGAAGACGCGCGACCCGCTCGGGGAGAGCCCTTGGCACC
GGGCCGTGGTCGCAGCTACG

Downstream 100 bases:

>100_bases
GCCGCGGGTGGCTCGTCCCATTACTTTGCGGCGGATCAGGGCAGTCGGTCGTTTTCTCTACGGATGGCTGCCGCGCACCC
TGCTCTGGCAGACCTTCCTG

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MRAMNTKTRCRVLLVDDDARLRELLSRYLQEQGFAVKAVVDAPMMDRALHREHFDLIVLDLMLPGEDGLAICRRLRGAEN
HIPIIMLTAKGDDVDRIVGLEMGADDYLPKPFNPRELVARIQAVMRRQPHSLPGAPTPEDEIVVFGRVRVNLGTRALTRD
GEEIQLTTGEFSLLKVLLQHPRQPLSRDKLMELARGREYGVFDRAIDVQVSRLRKLVEDDPAKPRYIQTVWGFGYVFVPD
DNKPAEAE

Sequences:

>Translated_248_residues
MRAMNTKTRCRVLLVDDDARLRELLSRYLQEQGFAVKAVVDAPMMDRALHREHFDLIVLDLMLPGEDGLAICRRLRGAEN
HIPIIMLTAKGDDVDRIVGLEMGADDYLPKPFNPRELVARIQAVMRRQPHSLPGAPTPEDEIVVFGRVRVNLGTRALTRD
GEEIQLTTGEFSLLKVLLQHPRQPLSRDKLMELARGREYGVFDRAIDVQVSRLRKLVEDDPAKPRYIQTVWGFGYVFVPD
DNKPAEAE
>Mature_248_residues
MRAMNTKTRCRVLLVDDDARLRELLSRYLQEQGFAVKAVVDAPMMDRALHREHFDLIVLDLMLPGEDGLAICRRLRGAEN
HIPIIMLTAKGDDVDRIVGLEMGADDYLPKPFNPRELVARIQAVMRRQPHSLPGAPTPEDEIVVFGRVRVNLGTRALTRD
GEEIQLTTGEFSLLKVLLQHPRQPLSRDKLMELARGREYGVFDRAIDVQVSRLRKLVEDDPAKPRYIQTVWGFGYVFVPD
DNKPAEAE

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=67.381974248927, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=41.025641025641, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=37.5545851528384, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1788394, Length=231, Percent_Identity=36.3636363636364, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=238, Percent_Identity=38.2352941176471, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=34.3347639484979, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=37.6623376623377, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI145693140, Length=241, Percent_Identity=36.5145228215768, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=33.4782608695652, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786911, Length=232, Percent_Identity=37.0689655172414, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.7719298245614, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87082012, Length=229, Percent_Identity=34.9344978165939, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=36.2068965517241, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.3612334801762, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=32.5396825396825, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=128, Percent_Identity=29.6875, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=102, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28231; Mature: 28231

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAMNTKTRCRVLLVDDDARLRELLSRYLQEQGFAVKAVVDAPMMDRALHREHFDLIVLD
CCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEEEE
LMLPGEDGLAICRRLRGAENHIPIIMLTAKGDDVDRIVGLEMGADDYLPKPFNPRELVAR
EEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHEEEEECCCCCCCCCCCCHHHHHHH
IQAVMRRQPHSLPGAPTPEDEIVVFGRVRVNLGTRALTRDGEEIQLTTGEFSLLKVLLQH
HHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHCCCCCEEEEECCHHHHHHHHHHC
PRQPLSRDKLMELARGREYGVFDRAIDVQVSRLRKLVEDDPAKPRYIQTVWGFGYVFVPD
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECC
DNKPAEAE
CCCCCCCC
>Mature Secondary Structure
MRAMNTKTRCRVLLVDDDARLRELLSRYLQEQGFAVKAVVDAPMMDRALHREHFDLIVLD
CCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCEEEEE
LMLPGEDGLAICRRLRGAENHIPIIMLTAKGDDVDRIVGLEMGADDYLPKPFNPRELVAR
EEECCCCHHHHHHHHCCCCCCCCEEEEEECCCCCHHEEEEECCCCCCCCCCCCHHHHHHH
IQAVMRRQPHSLPGAPTPEDEIVVFGRVRVNLGTRALTRDGEEIQLTTGEFSLLKVLLQH
HHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCHHHCCCCCEEEEECCHHHHHHHHHHC
PRQPLSRDKLMELARGREYGVFDRAIDVQVSRLRKLVEDDPAKPRYIQTVWGFGYVFVPD
CCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECC
DNKPAEAE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]