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The map label for this gene is cbf2 [C]

Identifier: 119897994

GI number: 119897994

Start: 1871903

End: 1872685

Strand: Reverse

Name: cbf2 [C]

Synonym: azo1703

Alternate gene names: 119897994

Gene position: 1872685-1871903 (Counterclockwise)

Preceding gene: 119897995

Following gene: 119897989

Centisome position: 42.79

GC content: 62.84

Gene sequence:

>783_bases
ATGAAACATTTTCCGAGCCGTCTCGCCCTCTTCCTGCTTGCCGGCTTCCTGACCCATGCCGCGCACGCCGCCGACGCCGT
GGCGACCGTCAATGGCACGGCCATCCCGGCCGCCCGCAGCGAAGCCATGCTGGCCGAACAGCGCGCCCAGGGCGCTCAGG
ACAACCCGCAACTGCGCGATGCCGTCCGCGAGGAACTGGTTCGCCGCGAAGTATTGAGCCAGGAGGCGGGCAAGAAGGGC
ATCGACAAGAAGGCCGACATCCAGGCCCAGATGGACATGGCCAAGCAGGCGGTGCTGATTCGCGCCTACCTGCAGGACTA
CGTGAAGAACAATCCGGTGACCGATGCCGAACTCAAGAAAGAGTACGACTCGATCAAGAGCCGCATGGGCGACAAGGAAT
ACAAGCCGCGTCACGTGCTGGTGGAAAGCGAAGAGCACGCCAAGGAAATCATCGGCAAGCTCAACGGTGGCGCCAAGTTT
GACGACCTCGCCAAGGAGTCGCGCGACCCTGGCTCCAAGGACAAGGGCGGTGACCTCGGCTGGACGACCCCGGACCGTTT
CGTGAAGCCCTTCTCCGACGCCATGGTGAAGCTCGAAAAGGGCAAGTACACCGCCGCGCCGGTCAAGAGCGACTACGGCT
TCCACGTCATCATGCTGGACGACGTGCGCGAGCTGAAGGCGCCTCCGTTCGAGGAGGTCAAGCCGCAGTTGCAACAGCGC
CTGCAGCAGCAGAAGGTCGAGAAGCACATCCTCGATCTGCGCACCAAGGCCAAGGTCCAGTAA

Upstream 100 bases:

>100_bases
CGGCGCTGGACGACCTGATGAAGACCCAGATCCATGCGCTCGCCATACGCGCACTCACGGCCAGCGAGGCCAGTATGCAA
CCCAACCAGAAGGAACCCCG

Downstream 100 bases:

>100_bases
GACCGTCGCCTGACAAAGAAAAGGCCGGCTCCGCGGAGCCGGCCTTTTCCTTTTTGGGGAGGGAAAAAATGCCCTCCCGC
TCCCACTGCCTTAGAACAGG

Product: putative cell binding factor

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKHFPSRLALFLLAGFLTHAAHAADAVATVNGTAIPAARSEAMLAEQRAQGAQDNPQLRDAVREELVRREVLSQEAGKKG
IDKKADIQAQMDMAKQAVLIRAYLQDYVKNNPVTDAELKKEYDSIKSRMGDKEYKPRHVLVESEEHAKEIIGKLNGGAKF
DDLAKESRDPGSKDKGGDLGWTTPDRFVKPFSDAMVKLEKGKYTAAPVKSDYGFHVIMLDDVRELKAPPFEEVKPQLQQR
LQQQKVEKHILDLRTKAKVQ

Sequences:

>Translated_260_residues
MKHFPSRLALFLLAGFLTHAAHAADAVATVNGTAIPAARSEAMLAEQRAQGAQDNPQLRDAVREELVRREVLSQEAGKKG
IDKKADIQAQMDMAKQAVLIRAYLQDYVKNNPVTDAELKKEYDSIKSRMGDKEYKPRHVLVESEEHAKEIIGKLNGGAKF
DDLAKESRDPGSKDKGGDLGWTTPDRFVKPFSDAMVKLEKGKYTAAPVKSDYGFHVIMLDDVRELKAPPFEEVKPQLQQR
LQQQKVEKHILDLRTKAKVQ
>Mature_260_residues
MKHFPSRLALFLLAGFLTHAAHAADAVATVNGTAIPAARSEAMLAEQRAQGAQDNPQLRDAVREELVRREVLSQEAGKKG
IDKKADIQAQMDMAKQAVLIRAYLQDYVKNNPVTDAELKKEYDSIKSRMGDKEYKPRHVLVESEEHAKEIIGKLNGGAKF
DDLAKESRDPGSKDKGGDLGWTTPDRFVKPFSDAMVKLEKGKYTAAPVKSDYGFHVIMLDDVRELKAPPFEEVKPQLQQR
LQQQKVEKHILDLRTKAKVQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=104, Percent_Identity=40.3846153846154, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786645, Length=141, Percent_Identity=31.9148936170213, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17537235, Length=102, Percent_Identity=41.1764705882353, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29100; Mature: 29100

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHFPSRLALFLLAGFLTHAAHAADAVATVNGTAIPAARSEAMLAEQRAQGAQDNPQLRD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
AVREELVRREVLSQEAGKKGIDKKADIQAQMDMAKQAVLIRAYLQDYVKNNPVTDAELKK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
EYDSIKSRMGDKEYKPRHVLVESEEHAKEIIGKLNGGAKFDDLAKESRDPGSKDKGGDLG
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCC
WTTPDRFVKPFSDAMVKLEKGKYTAAPVKSDYGFHVIMLDDVRELKAPPFEEVKPQLQQR
CCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEECCHHHHCCCCHHHHHHHHHHH
LQQQKVEKHILDLRTKAKVQ
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKHFPSRLALFLLAGFLTHAAHAADAVATVNGTAIPAARSEAMLAEQRAQGAQDNPQLRD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHH
AVREELVRREVLSQEAGKKGIDKKADIQAQMDMAKQAVLIRAYLQDYVKNNPVTDAELKK
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
EYDSIKSRMGDKEYKPRHVLVESEEHAKEIIGKLNGGAKFDDLAKESRDPGSKDKGGDLG
HHHHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCC
WTTPDRFVKPFSDAMVKLEKGKYTAAPVKSDYGFHVIMLDDVRELKAPPFEEVKPQLQQR
CCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCEEEEEECCHHHHCCCCHHHHHHHHHHH
LQQQKVEKHILDLRTKAKVQ
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]