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The map label for this gene is ppx [H]

Identifier: 119897981

GI number: 119897981

Start: 1858259

End: 1859809

Strand: Direct

Name: ppx [H]

Synonym: azo1690

Alternate gene names: 119897981

Gene position: 1858259-1859809 (Clockwise)

Preceding gene: 119897979

Following gene: 119897982

Centisome position: 42.46

GC content: 67.63

Gene sequence:

>1551_bases
ATGCTAGAATCGGGGCCTTTCGCAGCGTCGCAAGGCCCTCCCGTTGTCATGATGAAAGAACTGATCGCCGCGATTGACCT
CGGTTCCAACAGCTTCCGTTTGCAGGTCGGTCGGATCGTCAACGACCAGATCTACCCGCTGGACGGGCTGAAGGAGCCAG
TGCGGCTGGCCGCGGGCCTATCCCCCGAAAAATGGCTGGACCTCGCCGCCCAGCAGCGGGGCGTCGCCGCGCTGCAACGC
TTCCACGAACGCCTTGGCGGCTTTCCGCTCGACTCCGTGCGGGCCGTGGCGACCAACACGCTGCGGGTGGCCAAGAACGC
GCCGGAATTCCTGATCCGCGCCGAAGCCGCGCTCGGTTTTCCGATCGAGGTGATCGCGGGCCGCGAGGAAGCGCGCCTGA
TCTACGTCGGCGTCGCGCACACGTTGCCCAATCCGCACCGCCAGCAACTGGTGGTGGACATCGGCGGCGGCTCCACCGAG
TTCATCATCGGCAAGAGCTTCCAGCCGCTGCTGCTCGAGTCGCTCTACATGGGCTGCGTCGGCTACAGCCTGAACTACTT
CCCCGACGGCCGCGTCGACAAGAAGGGCATGAAGGATGCCGAGCTGGCGGCGCGGCGCGAACTCCAGGCCATCGCCCATG
CTTACCGCGAGGCCGGTTGGGAAGAGGCGGTGGGTTCCAGCGGCTCGGCGAAGGCGCTCGCGGAAATCCTGGAGCAGAAC
GGCCTCTCGGACGGCGGCATCACCCGCAACGGGCTGGAGAAGCTAAAGACGATCCTGCTGCGCGCCGGCAACATCAATGC
GGTGGATCTTCCCGGCCTGAAGGGCGACCGCATCCCGGTGCTGCTCGGGGGGCTTGCAATCATGAGCGCGGTGTTCAAGG
AGTTCGGCCTGGAGCGCATGGTGTTCTCGGAAGGCGCGCTGCGTCTTGGCGTGCTGTACGACCTGCTCGGACGCTACCAC
CATCACGACCTGCGCGATGCCACGGTGGCGGGATTCGTGCAGCGCTACGGCATCGACGTGCGCCAGGCCGAACAGGTGGC
CGACACCGCGTGCGCCTTCCTGGCACAGCTGGAGCCGGCGGCCGCCGCGCCCGAACATCCCGACCGCCGCTTCCTGCGCT
GGGCGGCGATGCTGCACGAGGTCGGCATCTCGATCGCGCATTCCAGCTATCACAAGCATTCCGCCTACATTCTCGCCAAT
GCCGACATGCCGGGTTTTTCGCGCATGGACCAGGGGCGGCTGTCGCGCATCGTGCTGGCCCACCGCGGCAAGCTGGAGCG
CGTTGCGGCCATCGACCCGGGCAGCTCGGACTGGCTGCTGATCGCCTGTCTGCGGCTTGCCGCCGTGTTGCACCGCGCGC
GTGATGCTCGCGGGGTGCCGCCGATCACGCTGGCGCGCGAGGGGCGCGGGTTTTCCGTCAATACGGCGCCGGGCTGGCTG
CAGAAGCTGCCCTTGACCGCCGCGGCGCTCGATGAAGAGCAGCGCCAGTGGCTGTCGGTCGGGCGCGGCCTTTTCGTGCG
CTCGCCCAGTGGGCGCAGCCAACCGGCCTGA

Upstream 100 bases:

>100_bases
TTGTACATGTGCTGTCCGGCGCAGAGTGACCGGCGCTGATTATGTGACATTTCCATTGCGTTTACATGACGGCCGCCAGG
GCGGGCGGGGCCGGGCGGCG

Downstream 100 bases:

>100_bases
GGCCATGAGCGCCGCCGCCCGGCCGCTCGACGGGGGCGCCCGCCCTTCCTCGGGAAGGCTGTCGATCGGCGACCGCGGGG
TGAGCCGGTGAGGGCGGAGG

Product: putative exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MLESGPFAASQGPPVVMMKELIAAIDLGSNSFRLQVGRIVNDQIYPLDGLKEPVRLAAGLSPEKWLDLAAQQRGVAALQR
FHERLGGFPLDSVRAVATNTLRVAKNAPEFLIRAEAALGFPIEVIAGREEARLIYVGVAHTLPNPHRQQLVVDIGGGSTE
FIIGKSFQPLLLESLYMGCVGYSLNYFPDGRVDKKGMKDAELAARRELQAIAHAYREAGWEEAVGSSGSAKALAEILEQN
GLSDGGITRNGLEKLKTILLRAGNINAVDLPGLKGDRIPVLLGGLAIMSAVFKEFGLERMVFSEGALRLGVLYDLLGRYH
HHDLRDATVAGFVQRYGIDVRQAEQVADTACAFLAQLEPAAAAPEHPDRRFLRWAAMLHEVGISIAHSSYHKHSAYILAN
ADMPGFSRMDQGRLSRIVLAHRGKLERVAAIDPGSSDWLLIACLRLAAVLHRARDARGVPPITLAREGRGFSVNTAPGWL
QKLPLTAAALDEEQRQWLSVGRGLFVRSPSGRSQPA

Sequences:

>Translated_516_residues
MLESGPFAASQGPPVVMMKELIAAIDLGSNSFRLQVGRIVNDQIYPLDGLKEPVRLAAGLSPEKWLDLAAQQRGVAALQR
FHERLGGFPLDSVRAVATNTLRVAKNAPEFLIRAEAALGFPIEVIAGREEARLIYVGVAHTLPNPHRQQLVVDIGGGSTE
FIIGKSFQPLLLESLYMGCVGYSLNYFPDGRVDKKGMKDAELAARRELQAIAHAYREAGWEEAVGSSGSAKALAEILEQN
GLSDGGITRNGLEKLKTILLRAGNINAVDLPGLKGDRIPVLLGGLAIMSAVFKEFGLERMVFSEGALRLGVLYDLLGRYH
HHDLRDATVAGFVQRYGIDVRQAEQVADTACAFLAQLEPAAAAPEHPDRRFLRWAAMLHEVGISIAHSSYHKHSAYILAN
ADMPGFSRMDQGRLSRIVLAHRGKLERVAAIDPGSSDWLLIACLRLAAVLHRARDARGVPPITLAREGRGFSVNTAPGWL
QKLPLTAAALDEEQRQWLSVGRGLFVRSPSGRSQPA
>Mature_516_residues
MLESGPFAASQGPPVVMMKELIAAIDLGSNSFRLQVGRIVNDQIYPLDGLKEPVRLAAGLSPEKWLDLAAQQRGVAALQR
FHERLGGFPLDSVRAVATNTLRVAKNAPEFLIRAEAALGFPIEVIAGREEARLIYVGVAHTLPNPHRQQLVVDIGGGSTE
FIIGKSFQPLLLESLYMGCVGYSLNYFPDGRVDKKGMKDAELAARRELQAIAHAYREAGWEEAVGSSGSAKALAEILEQN
GLSDGGITRNGLEKLKTILLRAGNINAVDLPGLKGDRIPVLLGGLAIMSAVFKEFGLERMVFSEGALRLGVLYDLLGRYH
HHDLRDATVAGFVQRYGIDVRQAEQVADTACAFLAQLEPAAAAPEHPDRRFLRWAAMLHEVGISIAHSSYHKHSAYILAN
ADMPGFSRMDQGRLSRIVLAHRGKLERVAAIDPGSSDWLLIACLRLAAVLHRARDARGVPPITLAREGRGFSVNTAPGWL
QKLPLTAAALDEEQRQWLSVGRGLFVRSPSGRSQPA

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=486, Percent_Identity=41.7695473251029, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI48994966, Length=484, Percent_Identity=38.8429752066116, Blast_Score=290, Evalue=1e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 56030; Mature: 56030

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESGPFAASQGPPVVMMKELIAAIDLGSNSFRLQVGRIVNDQIYPLDGLKEPVRLAAGL
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECEECCCCCCCCCCCCHHHHHHCCC
SPEKWLDLAAQQRGVAALQRFHERLGGFPLDSVRAVATNTLRVAKNAPEFLIRAEAALGF
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEHHHHCCC
PIEVIAGREEARLIYVGVAHTLPNPHRQQLVVDIGGGSTEFIIGKSFQPLLLESLYMGCV
CEEEECCCCCCEEEEEEEHHCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHH
GYSLNYFPDGRVDKKGMKDAELAARRELQAIAHAYREAGWEEAVGSSGSAKALAEILEQN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHC
GLSDGGITRNGLEKLKTILLRAGNINAVDLPGLKGDRIPVLLGGLAIMSAVFKEFGLERM
CCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
VFSEGALRLGVLYDLLGRYHHHDLRDATVAGFVQRYGIDVRQAEQVADTACAFLAQLEPA
HHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
AAAPEHPDRRFLRWAAMLHEVGISIAHSSYHKHSAYILANADMPGFSRMDQGRLSRIVLA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
HRGKLERVAAIDPGSSDWLLIACLRLAAVLHRARDARGVPPITLAREGRGFSVNTAPGWL
HCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHH
QKLPLTAAALDEEQRQWLSVGRGLFVRSPSGRSQPA
HHCCCHHHHHCHHHHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure
MLESGPFAASQGPPVVMMKELIAAIDLGSNSFRLQVGRIVNDQIYPLDGLKEPVRLAAGL
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECEECCCCCCCCCCCCHHHHHHCCC
SPEKWLDLAAQQRGVAALQRFHERLGGFPLDSVRAVATNTLRVAKNAPEFLIRAEAALGF
CHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEEHHHHCCC
PIEVIAGREEARLIYVGVAHTLPNPHRQQLVVDIGGGSTEFIIGKSFQPLLLESLYMGCV
CEEEECCCCCCEEEEEEEHHCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHH
GYSLNYFPDGRVDKKGMKDAELAARRELQAIAHAYREAGWEEAVGSSGSAKALAEILEQN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHC
GLSDGGITRNGLEKLKTILLRAGNINAVDLPGLKGDRIPVLLGGLAIMSAVFKEFGLERM
CCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHHH
VFSEGALRLGVLYDLLGRYHHHDLRDATVAGFVQRYGIDVRQAEQVADTACAFLAQLEPA
HHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
AAAPEHPDRRFLRWAAMLHEVGISIAHSSYHKHSAYILANADMPGFSRMDQGRLSRIVLA
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
HRGKLERVAAIDPGSSDWLLIACLRLAAVLHRARDARGVPPITLAREGRGFSVNTAPGWL
HCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHH
QKLPLTAAALDEEQRQWLSVGRGLFVRSPSGRSQPA
HHCCCHHHHHCHHHHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]