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The map label for this gene is aroF [H]

Identifier: 119897960

GI number: 119897960

Start: 1831527

End: 1832603

Strand: Reverse

Name: aroF [H]

Synonym: azo1669

Alternate gene names: 119897960

Gene position: 1832603-1831527 (Counterclockwise)

Preceding gene: 119897963

Following gene: 119897959

Centisome position: 41.88

GC content: 67.69

Gene sequence:

>1077_bases
ATGTCTGTCGCCCAGACCGAAAACCTCAACATCGCCACCGTCGACCACATGCCGTCGCCCGAAGAGATCAAGGCGCGCGT
GCCGCTGTCCGACCGCGCGGCGGCCACCGTGTTGGCGGGGCGCAAGGCGCTCGCCGACATCCTCGAAGGCCGCGACAAGC
GCCTGTTCGTCGTCGTCGGCCCCTGCTCCATCCACGACCCGGTCGCCGGGCTGGACTACGCGCGGCGCCTGAAGGCGCTC
GCCGACGAAGTCTCCGACACCATGCTGCTGGTGATGCGCGTCTATTTCGAGAAGCCGCGTACCTCGACCGGCTGGAAGGG
CTTCATCAACGACCCCTTCATGGACGACTCCTTCCGCATCGACGTGGGCATGGAAAAGGCCCGCCGCTTCCTGCTCGACG
TGTGCGAGATCGGCCTGCCCACCGGCACCGAGGCGCTGGACCCGAACGCGCCCCAGTACTACGGCGACCTGGTGACGTGG
ACCGCGATCGGTGCCCGTACCTCGGAATCGCAGACCCACCGGGAGATGGCCTCCGGGCTGTCGACCCCGGTGGGCTTCAA
GAACGCCACCGACGGCGATCTTGAAGTGGCGATCAACGCGATCATCTCGGCGGCGCACCCGCACAGTTTTCTCGGCATCA
ACGGCCAGGGTCAGTCCGCCATCCTGCGCACCCGCGGCAACCGCCACGGCCATGTGGTGCTGCGCGGCGGCGGCGGCCGC
CCCAACTACGACACGGTGTCGGTGTCGCTTGCCGAGCAGGCGCTGGCCAAGGCCAAGCTGCCGGTGAACATCGTGGTCGA
TTGTTCGCACGCCAACTCGTGGAAGAAGCCCGAGTTGCAGCCGCTGGTGATGAAGGACGTGATCCACCAGATCCGCGAAG
GCAACCGCTCGGTGGTCGGGCTGATGATCGAGAGCAACCTCGAAGCCGGCAACCAGGCGATCCCGGCCGACCTGTCGCAG
CTGAAGTACGGCTGTTCGGTCACCGACGCCTGCGTGGGCTGGGACACGACGGTGGACATGATCCGCAGCGCCCACGGCGT
GCTGCGCGACGCGCTGGCCCGCCGGGAGCGCGCATGA

Upstream 100 bases:

>100_bases
GGCATGCGTCACGCCCCGCGGCATCGACACCGCCGCAGGCGAGCCGAAGCCCTTCGGAGTTACAATTCCGCCTTTTCCAG
GCCGCATCCGGGAGCGCCTC

Downstream 100 bases:

>100_bases
ACCTTGTCGTGCAGGGCGCGGACGTCGATACGGTCGCGCTCAAGGCGCTCGCCAAGCTCACAGCGGCGCGCGGCATCGAG
CAGGTCACGGCCGAGTCTTT

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSVAQTENLNIATVDHMPSPEEIKARVPLSDRAAATVLAGRKALADILEGRDKRLFVVVGPCSIHDPVAGLDYARRLKAL
ADEVSDTMLLVMRVYFEKPRTSTGWKGFINDPFMDDSFRIDVGMEKARRFLLDVCEIGLPTGTEALDPNAPQYYGDLVTW
TAIGARTSESQTHREMASGLSTPVGFKNATDGDLEVAINAIISAAHPHSFLGINGQGQSAILRTRGNRHGHVVLRGGGGR
PNYDTVSVSLAEQALAKAKLPVNIVVDCSHANSWKKPELQPLVMKDVIHQIREGNRSVVGLMIESNLEAGNQAIPADLSQ
LKYGCSVTDACVGWDTTVDMIRSAHGVLRDALARRERA

Sequences:

>Translated_358_residues
MSVAQTENLNIATVDHMPSPEEIKARVPLSDRAAATVLAGRKALADILEGRDKRLFVVVGPCSIHDPVAGLDYARRLKAL
ADEVSDTMLLVMRVYFEKPRTSTGWKGFINDPFMDDSFRIDVGMEKARRFLLDVCEIGLPTGTEALDPNAPQYYGDLVTW
TAIGARTSESQTHREMASGLSTPVGFKNATDGDLEVAINAIISAAHPHSFLGINGQGQSAILRTRGNRHGHVVLRGGGGR
PNYDTVSVSLAEQALAKAKLPVNIVVDCSHANSWKKPELQPLVMKDVIHQIREGNRSVVGLMIESNLEAGNQAIPADLSQ
LKYGCSVTDACVGWDTTVDMIRSAHGVLRDALARRERA
>Mature_357_residues
SVAQTENLNIATVDHMPSPEEIKARVPLSDRAAATVLAGRKALADILEGRDKRLFVVVGPCSIHDPVAGLDYARRLKALA
DEVSDTMLLVMRVYFEKPRTSTGWKGFINDPFMDDSFRIDVGMEKARRFLLDVCEIGLPTGTEALDPNAPQYYGDLVTWT
AIGARTSESQTHREMASGLSTPVGFKNATDGDLEVAINAIISAAHPHSFLGINGQGQSAILRTRGNRHGHVVLRGGGGRP
NYDTVSVSLAEQALAKAKLPVNIVVDCSHANSWKKPELQPLVMKDVIHQIREGNRSVVGLMIESNLEAGNQAIPADLSQL
KYGCSVTDACVGWDTTVDMIRSAHGVLRDALARRERA

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=348, Percent_Identity=56.0344827586207, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1786969, Length=338, Percent_Identity=50.5917159763314, Blast_Score=346, Evalue=1e-96,
Organism=Escherichia coli, GI1787996, Length=337, Percent_Identity=45.1038575667656, Blast_Score=310, Evalue=9e-86,
Organism=Saccharomyces cerevisiae, GI6319726, Length=354, Percent_Identity=48.0225988700565, Blast_Score=336, Evalue=3e-93,
Organism=Saccharomyces cerevisiae, GI6320240, Length=337, Percent_Identity=45.9940652818991, Blast_Score=316, Evalue=3e-87,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38829; Mature: 38698

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVAQTENLNIATVDHMPSPEEIKARVPLSDRAAATVLAGRKALADILEGRDKRLFVVVG
CCCCCCCCCEEEEECCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PCSIHDPVAGLDYARRLKALADEVSDTMLLVMRVYFEKPRTSTGWKGFINDPFMDDSFRI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
DVGMEKARRFLLDVCEIGLPTGTEALDPNAPQYYGDLVTWTAIGARTSESQTHREMASGL
ECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHEEEEECCCCCCHHHHHHHHHCC
STPVGFKNATDGDLEVAINAIISAAHPHSFLGINGQGQSAILRTRGNRHGHVVLRGGGGR
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCEEEEECCCCC
PNYDTVSVSLAEQALAKAKLPVNIVVDCSHANSWKKPELQPLVMKDVIHQIREGNRSVVG
CCCCEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
LMIESNLEAGNQAIPADLSQLKYGCSVTDACVGWDTTVDMIRSAHGVLRDALARRERA
EEEECCCCCCCCCCCCCHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVAQTENLNIATVDHMPSPEEIKARVPLSDRAAATVLAGRKALADILEGRDKRLFVVVG
CCCCCCCCEEEEECCCCCHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PCSIHDPVAGLDYARRLKALADEVSDTMLLVMRVYFEKPRTSTGWKGFINDPFMDDSFRI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEE
DVGMEKARRFLLDVCEIGLPTGTEALDPNAPQYYGDLVTWTAIGARTSESQTHREMASGL
ECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCHHEEEEECCCCCCHHHHHHHHHCC
STPVGFKNATDGDLEVAINAIISAAHPHSFLGINGQGQSAILRTRGNRHGHVVLRGGGGR
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCEEEEECCCCC
PNYDTVSVSLAEQALAKAKLPVNIVVDCSHANSWKKPELQPLVMKDVIHQIREGNRSVVG
CCCCEEEHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEE
LMIESNLEAGNQAIPADLSQLKYGCSVTDACVGWDTTVDMIRSAHGVLRDALARRERA
EEEECCCCCCCCCCCCCHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]