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The map label for this gene is fabF1 [H]

Identifier: 119897918

GI number: 119897918

Start: 1788940

End: 1790175

Strand: Direct

Name: fabF1 [H]

Synonym: azo1627

Alternate gene names: 119897918

Gene position: 1788940-1790175 (Clockwise)

Preceding gene: 119897917

Following gene: 119897919

Centisome position: 40.88

GC content: 62.78

Gene sequence:

>1236_bases
GTGTCGCGTCGTAGAGTCGTCGTCACCGGTCTGGGACTCGTCTCGCCGGTCGGCAATACTGTTCCCGTTGCTTGGGAAAA
CCTGCTTGCCGGCAAGAGCGGCATCGGGCCGATCACTCGTTTCGATGCCTCGGCGTTTGCTGCCCGCATCGCTGGCGAAG
TCAAGGATTTCGACGTTTCGGCCTACCTGTCGCCCAAGGAAGCCCGCCGCATGGATGTGTTCATCCACTACGGCATGGCG
GCCGGGATTCAGGCGATCCGTGATTCCGGCATTGAAGTCACCGAAGCCAACGCTGAGCGCATCGGCGTGAACATCGGCTC
GGGCATCGGCGGTCTGCCGATGATCGAGGAAACCCACGACGATTATCTTGCGGGCGGGCCGCGCAAGATTTCTCCGTTCT
TCATTCCGGGCACCATCATCAACATGATCTCGGGCAACCTGTCGATCATGTTTGGTCTGAAGGGGCCCAACATCGCGGTT
GTCACCGCGTGCACCACGGGCTTGCACGCCATCGGCACCAGTGCGCGGATGATCGAGTATGGCGACGCCGACGTGATGGT
GTGCGGCGGTGCCGAATCGACCGTCACCTCGCTCGCGATCGGCGGTTTCTCGTCCGCCAAGGCGCTTTCCACCCGCAACG
ACGACCCGGCCACCGCCAGCCGTCCGTGGGACAAGGGGCGTGACGGTTTCGTGCTCGGCGAAGGCGCCGGTGTCCTCGTG
CTGGAAGAGTACGAGCACGCGGTAAAGCGCGGTGCGCGCATCTACGCGGAACTGGCCGGTTTCGGCATGAGCGGCGACGC
TTTCCACATGACCGCGCCGGATACCGACGGGCCGCGCCGCAGCATGGTCAACGCCATGAAGAACGCGGGCGTCAACGTGG
ATGAGGTGCAGTACCTTAACGCGCACGGCACTTCTACGCCCCTCGGGGACAAGAACGAAACCGACGCGATCAAGCTTGCG
TTCGGTGTCGACGCGGCCAAGAAGCTTGTGGTCAATTCCACCAAGTCGATGACCGGCCACCTGCTGGGCGGCGCGGGCGG
ACTTGAGTCGGTATTCACGGTCCTCGCCGTCCATCACCAGATCTCGCCGCCGACGATCAACATCTTCGAGCAGGATCCCG
AGTGCGATCTCGACTACTGCGCCAACGAAGCGCGGCCGATGAAGATCGACGTTGCCATCAAGAACAACTTCGGCTTCGGC
GGTACCAACGGTACCCTCGTGTTCCGCCGGGTTTGA

Upstream 100 bases:

>100_bases
GCCCATCTGAAGAAGTAATTCCGCTTTTCATCCGGATTTCGCCTCGTCGAAATCCGGATCGATTCCAACCTCTCCGCCTC
GATTTATTACGGAGTTGCCT

Downstream 100 bases:

>100_bases
CCATACGGAGCATGGCAGGGCCATGCGATATCCGCTCGCGCTGGAACTGAAGTCTTCCCGCGGAATCGAGGCGTCAGTGT
TTGCGATGCATGGCATCGCG

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MSRRRVVVTGLGLVSPVGNTVPVAWENLLAGKSGIGPITRFDASAFAARIAGEVKDFDVSAYLSPKEARRMDVFIHYGMA
AGIQAIRDSGIEVTEANAERIGVNIGSGIGGLPMIEETHDDYLAGGPRKISPFFIPGTIINMISGNLSIMFGLKGPNIAV
VTACTTGLHAIGTSARMIEYGDADVMVCGGAESTVTSLAIGGFSSAKALSTRNDDPATASRPWDKGRDGFVLGEGAGVLV
LEEYEHAVKRGARIYAELAGFGMSGDAFHMTAPDTDGPRRSMVNAMKNAGVNVDEVQYLNAHGTSTPLGDKNETDAIKLA
FGVDAAKKLVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQISPPTINIFEQDPECDLDYCANEARPMKIDVAIKNNFGFG
GTNGTLVFRRV

Sequences:

>Translated_411_residues
MSRRRVVVTGLGLVSPVGNTVPVAWENLLAGKSGIGPITRFDASAFAARIAGEVKDFDVSAYLSPKEARRMDVFIHYGMA
AGIQAIRDSGIEVTEANAERIGVNIGSGIGGLPMIEETHDDYLAGGPRKISPFFIPGTIINMISGNLSIMFGLKGPNIAV
VTACTTGLHAIGTSARMIEYGDADVMVCGGAESTVTSLAIGGFSSAKALSTRNDDPATASRPWDKGRDGFVLGEGAGVLV
LEEYEHAVKRGARIYAELAGFGMSGDAFHMTAPDTDGPRRSMVNAMKNAGVNVDEVQYLNAHGTSTPLGDKNETDAIKLA
FGVDAAKKLVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQISPPTINIFEQDPECDLDYCANEARPMKIDVAIKNNFGFG
GTNGTLVFRRV
>Mature_410_residues
SRRRVVVTGLGLVSPVGNTVPVAWENLLAGKSGIGPITRFDASAFAARIAGEVKDFDVSAYLSPKEARRMDVFIHYGMAA
GIQAIRDSGIEVTEANAERIGVNIGSGIGGLPMIEETHDDYLAGGPRKISPFFIPGTIINMISGNLSIMFGLKGPNIAVV
TACTTGLHAIGTSARMIEYGDADVMVCGGAESTVTSLAIGGFSSAKALSTRNDDPATASRPWDKGRDGFVLGEGAGVLVL
EEYEHAVKRGARIYAELAGFGMSGDAFHMTAPDTDGPRRSMVNAMKNAGVNVDEVQYLNAHGTSTPLGDKNETDAIKLAF
GVDAAKKLVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQISPPTINIFEQDPECDLDYCANEARPMKIDVAIKNNFGFGG
TNGTLVFRRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=47.4820143884892, Blast_Score=363, Evalue=1e-100,
Organism=Homo sapiens, GI223972627, Length=166, Percent_Identity=47.5903614457831, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI41872631, Length=418, Percent_Identity=26.0765550239234, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=60.3864734299517, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788663, Length=412, Percent_Identity=37.1359223300971, Blast_Score=244, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI71983541, Length=415, Percent_Identity=34.6987951807229, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71983535, Length=256, Percent_Identity=38.671875, Blast_Score=178, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI212642053, Length=428, Percent_Identity=25.4672897196262, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=413, Percent_Identity=24.2130750605327, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=35.8574610244989, Blast_Score=258, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24644341, Length=419, Percent_Identity=41.7661097852029, Blast_Score=311, Evalue=5e-85,
Organism=Drosophila melanogaster, GI221330659, Length=375, Percent_Identity=25.0666666666667, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI19920632, Length=375, Percent_Identity=25.0666666666667, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24581345, Length=426, Percent_Identity=24.4131455399061, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43209; Mature: 43077

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRVVVTGLGLVSPVGNTVPVAWENLLAGKSGIGPITRFDASAFAARIAGEVKDFDVS
CCCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCHHCCHHHHHHHHHCCCCCCEEE
AYLSPKEARRMDVFIHYGMAAGIQAIRDSGIEVTEANAERIGVNIGSGIGGLPMIEETHD
EEECHHHHCEEEEEEEECHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCCCCCCCCC
DYLAGGPRKISPFFIPGTIINMISGNLSIMFGLKGPNIAVVTACTTGLHAIGTSARMIEY
HHHCCCCCCCCCEEECHHHHHHHCCCEEEEEEECCCCEEEEEEECCCHHHHCCCCEEEEE
GDADVMVCGGAESTVTSLAIGGFSSAKALSTRNDDPATASRPWDKGRDGFVLGEGAGVLV
CCCCEEEECCCCHHHHHEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAVKRGARIYAELAGFGMSGDAFHMTAPDTDGPRRSMVNAMKNAGVNVDEVQYLN
EHHHHHHHHHHHHEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEE
AHGTSTPLGDKNETDAIKLAFGVDAAKKLVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQ
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCHHCEEEECCCCCHHHHHHHHHHHHC
ISPPTINIFEQDPECDLDYCANEARPMKIDVAIKNNFGFGGTNGTLVFRRV
CCCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRRVVVTGLGLVSPVGNTVPVAWENLLAGKSGIGPITRFDASAFAARIAGEVKDFDVS
CCCEEEEEECCCCCCCCCCCCHHHHHHHCCCCCCCCCHHCCHHHHHHHHHCCCCCCEEE
AYLSPKEARRMDVFIHYGMAAGIQAIRDSGIEVTEANAERIGVNIGSGIGGLPMIEETHD
EEECHHHHCEEEEEEEECHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCCCCCCCCCCC
DYLAGGPRKISPFFIPGTIINMISGNLSIMFGLKGPNIAVVTACTTGLHAIGTSARMIEY
HHHCCCCCCCCCEEECHHHHHHHCCCEEEEEEECCCCEEEEEEECCCHHHHCCCCEEEEE
GDADVMVCGGAESTVTSLAIGGFSSAKALSTRNDDPATASRPWDKGRDGFVLGEGAGVLV
CCCCEEEECCCCHHHHHEEECCCCCCHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAVKRGARIYAELAGFGMSGDAFHMTAPDTDGPRRSMVNAMKNAGVNVDEVQYLN
EHHHHHHHHHHHHEEEHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCHHHEEEEE
AHGTSTPLGDKNETDAIKLAFGVDAAKKLVVNSTKSMTGHLLGGAGGLESVFTVLAVHHQ
CCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCCCCHHCEEEECCCCCHHHHHHHHHHHHC
ISPPTINIFEQDPECDLDYCANEARPMKIDVAIKNNFGFGGTNGTLVFRRV
CCCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]