Click here to switch to the map view.

The map label for this gene is gph [C]

Identifier: 119897906

GI number: 119897906

Start: 1780691

End: 1781347

Strand: Direct

Name: gph [C]

Synonym: azo1615

Alternate gene names: 119897906

Gene position: 1780691-1781347 (Clockwise)

Preceding gene: 119897905

Following gene: 119897907

Centisome position: 40.69

GC content: 68.04

Gene sequence:

>657_bases
GTGGCTGACCGCTTCGATCTGGTTGTTTTCGACTGGGACGGCACGCTGATGGATTCGGCGGCGGCGATCGTGCGCGCCAT
CCTCGCCGCCTGCCGTGACCTCGGTCTGCCCGAGCCGCCTGAGGAGCGGGCGCGCTACGTCATCGGCCTGGGGCTGGGCG
ATGCGTTGCGGCACGCGGTGCCGGAACTCGATGTCGAGGCCTATCCGCGCATGGTCGAGCGTTATCGCCATCATTACCTG
TCGGCCGACCACGAGCTGACGCTCTTTCCCGGCGTGCCCGGCATGATCGACTGGCTGGCCGAGGAGGGAAAGCTGCTGGC
GGTGGCAACCGGGAAGAGCCGCCTCGGGCTGGACCGCGCGCTGTCGCATTCGGGGCTGGGGCCGCGCTTCCATGCAACGC
GGTGTGCCGACGAGTGCTTTTCGAAGCCGCATCCGGCCATGCTGGAAGAGTTGATGGATGAACTGGGGGTGGCTCGGGAC
CGCACACTGATGATCGGCGACACCACCCACGATCTGCAGATGGCGCATAACGCCGGCGTGGCCGGGCTTGCGGTCGGGTT
CGGTGCGCATGGCCGTGCAGAACTCGAGGCGGCGCGCCCGCTCGCCTATGTGGAAACGCCGGCGGCGCTCGAGCAATGGC
TGCGCGGGAACGTCTGA

Upstream 100 bases:

>100_bases
CACCATCCGCTGACCGGCGAGTTGCTCGCATTCGAGGCGGCGCTGCCGGACGATCTGCGGGGCTTCGTCGCCCTGCTCGA
TACCAAGGAGGGCAAGTCCC

Downstream 100 bases:

>100_bases
TCTGTGCGGCCAGCGAACTGGCGGATGGCGGCGACGGGGTGCGGTTCACGGTAGAGCGCTTCGGCGTGGTGGAGCCGGCC
TTTGCAGTTCGCTACCGGGG

Product: hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MADRFDLVVFDWDGTLMDSAAAIVRAILAACRDLGLPEPPEERARYVIGLGLGDALRHAVPELDVEAYPRMVERYRHHYL
SADHELTLFPGVPGMIDWLAEEGKLLAVATGKSRLGLDRALSHSGLGPRFHATRCADECFSKPHPAMLEELMDELGVARD
RTLMIGDTTHDLQMAHNAGVAGLAVGFGAHGRAELEAARPLAYVETPAALEQWLRGNV

Sequences:

>Translated_218_residues
MADRFDLVVFDWDGTLMDSAAAIVRAILAACRDLGLPEPPEERARYVIGLGLGDALRHAVPELDVEAYPRMVERYRHHYL
SADHELTLFPGVPGMIDWLAEEGKLLAVATGKSRLGLDRALSHSGLGPRFHATRCADECFSKPHPAMLEELMDELGVARD
RTLMIGDTTHDLQMAHNAGVAGLAVGFGAHGRAELEAARPLAYVETPAALEQWLRGNV
>Mature_217_residues
ADRFDLVVFDWDGTLMDSAAAIVRAILAACRDLGLPEPPEERARYVIGLGLGDALRHAVPELDVEAYPRMVERYRHHYLS
ADHELTLFPGVPGMIDWLAEEGKLLAVATGKSRLGLDRALSHSGLGPRFHATRCADECFSKPHPAMLEELMDELGVARDR
TLMIGDTTHDLQMAHNAGVAGLAVGFGAHGRAELEAARPLAYVETPAALEQWLRGNV

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23799; Mature: 23668

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRFDLVVFDWDGTLMDSAAAIVRAILAACRDLGLPEPPEERARYVIGLGLGDALRHAV
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEECCHHHHHHHC
PELDVEAYPRMVERYRHHYLSADHELTLFPGVPGMIDWLAEEGKLLAVATGKSRLGLDRA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCEEEEECCCCHHHHHHH
LSHSGLGPRFHATRCADECFSKPHPAMLEELMDELGVARDRTLMIGDTTHDLQMAHNAGV
HHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCH
AGLAVGFGAHGRAELEAARPLAYVETPAALEQWLRGNV
HHHHCCCCCCCCCHHHHHCCCCEEECHHHHHHHHCCCC
>Mature Secondary Structure 
ADRFDLVVFDWDGTLMDSAAAIVRAILAACRDLGLPEPPEERARYVIGLGLGDALRHAV
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEECCHHHHHHHC
PELDVEAYPRMVERYRHHYLSADHELTLFPGVPGMIDWLAEEGKLLAVATGKSRLGLDRA
CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCEEEEECCCCHHHHHHH
LSHSGLGPRFHATRCADECFSKPHPAMLEELMDELGVARDRTLMIGDTTHDLQMAHNAGV
HHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCH
AGLAVGFGAHGRAELEAARPLAYVETPAALEQWLRGNV
HHHHCCCCCCCCCHHHHHCCCCEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA