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The map label for this gene is ppiD [H]

Identifier: 119897859

GI number: 119897859

Start: 1724061

End: 1725956

Strand: Direct

Name: ppiD [H]

Synonym: azo1568

Alternate gene names: 119897859

Gene position: 1724061-1725956 (Clockwise)

Preceding gene: 119897857

Following gene: 119897861

Centisome position: 39.4

GC content: 68.62

Gene sequence:

>1896_bases
ATGTTCGACGCTGTTCGCAACAACAAGCGGGTGGCCCAGATCATTCTGGCCCTGCTCATCATCCCCTTCGCATTCTTCGG
CCTCGACGCCTATTTCAAGGACGGTCCCGGCGGTGGCGAAGTCGCCGTCGTCGATGGGGCGCCGATCACGGCGGCCGAGT
TCGACCGCGCGCTGCGTGAGCGCCAGGATCGCCTGCGCAACGAAATGGGCGGTCCGGTGGATAGCGCCCTGCTCGAATCG
CCGGCGCTGCGCCGCGCGGTGCTCGAAACCATGGTCAGCCAGCGTCTGCTCGCGCGCTATGCGGCGGACCGTCACATGGT
GGTGACGCCGCAGCAACTGCAGGAGACGATTGCCGCGGTGGAGGCCTTCCACGAGAACGGCCAGTTCTCGCTGCAGCGCT
ATCAGGATGTGCTGCGCGCGCAGAACATGACGCCTGCGGGTTTCGAAGCCCGGCTGGCGCAGGATGTGCGCATCCAGCAA
CTGGCCGCGTCGATCGGCGAAGCGGCGTTTACCCCGGCCGCATCGGCCAAGCGCTTCCTGCTCGCGCAGCTCGAAGAGCG
CGAGGTACGCGAATTGCGTTTCCCCGCCAGCCGCTACCTCGGCGAGGTCAAGCTGGCCGATGGCGCGGCGCAGGCCTTCT
ACGACGCCAACGCAGCGGGCTTCGAGCAGCCGGCGCGGCTGAAGGCGGAATACGTGGTGCTGGACGAAGCCGCGCTGGCG
AAGCAGGTCAAGGTTTCGGACGAGGAAGTCCGCGCGTTCTACGACGGCAATCCGGGCCGTTTCGGCCAGCCGGAAGAGCG
TCGTGCGCGCCACATCCTGATCCAGGTGGATGCCGGCGCGCCTGAGGCGGAGGTGGCCAAGGCCAAGGCCGCGATCGACG
AGATTGCCGCCACCCTCGCCAAGGATCCGGGCCGTTTCGAGGCGCTCGCCAAGGCATCGTCGCAGGACTCGGGTTCGGCC
GCGCGCGGCGGGGATCTCGGCTTCTTCGGTCGGGGCGCGATGGTCAAGCCGTTCGAGGACGCGGCCTTCGGTCAGGCCAA
GGGCGTCGTCGGTCCGGTGGTGCGCTCCGATTTCGGTTTCCACATCATCCAGGTGACCGACATCAAGCCGGCGACCACGC
GTTCGCTGGACAGCGTGCGCGGCGAGATCGTGGACGAACTGCGCAAGCAGGCGGCCGGGCGTCGTTTTGCCGAAGTCGCC
AACGATTTCTCCAATATGGTCTACGAGCAGCCGGACAGCCTGAAGCCGGTGGCGGAGCAGTTCGGCCTCGAGGTGCGGAC
CAGCGACTGGGTGCAGCGCGGTGCCGACGCGGTGGGTAGCGTCAGCAGCAGCAAGCTGGTGGATGCGCTGTTTGCCGAAG
ACGCGAGCAAGAACGGCCGCAACACCCAGGCGATCGAACTGGGTCCGAACGCGCTGGCGGCGGGGCGGGTGGCGGCGTTC
GAGCCGGCCCAGCGCCTGCCGTTCGATCAGGTCCGGGCCGAGATCGAGCAGCAATTGCGCAACGAAGAGGCCGCCAAGCT
GGCCACCGAGCGTGGCAGCGCTGCGCTCGCCGCCCTGGAAAAGGGCGAGGCTGCGGGCGGCGAGTTTTCGGCCGCGCGCA
AGCTCCAGCGCGGCGCGCCGGCGCTGCCCGCCGCGGCGATGCAGGCCGTCTTCGCGGCCCCGTCCGGAAAGCTGCCGGCG
CACGTCGGCGTTGCGCTGCCGGAAGGGGGCTACGCGGTTTATCGCATCGATGCGGTCAACCGCCCCGTGCTGGCGGATGA
TGATCCCCGCATCGCGGCCGTCGCCTCGCAGTATTCGCGCATGGTCGCGGAGCGCGATTTCGGCAGTTTCCTTGCCGGGC
TGCGGGAGCGCTACAAGGTCGAGATCAAGCTGCCGGCCGCCCCGCCGCGCGAATAG

Upstream 100 bases:

>100_bases
CGGATCGCGGCCAGCACACGCCGGATGCGCTACACTCCGGCCTCCGGCGCCGGCCCGTCCCGCCGTTCGTCGTATTCCCG
CTGCTTATACGGAAATCAAG

Downstream 100 bases:

>100_bases
CGGACAGTGGCAAAAAGAAAAACGCCCGGTCCAAGCCGGGCGTTTTTTCATGCGGCGGCGGTGTGCCGCGCGCGTCGGGT
TCAGACCTGTTCGGAGTTGC

Product: putative peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 631; Mature: 631

Protein sequence:

>631_residues
MFDAVRNNKRVAQIILALLIIPFAFFGLDAYFKDGPGGGEVAVVDGAPITAAEFDRALRERQDRLRNEMGGPVDSALLES
PALRRAVLETMVSQRLLARYAADRHMVVTPQQLQETIAAVEAFHENGQFSLQRYQDVLRAQNMTPAGFEARLAQDVRIQQ
LAASIGEAAFTPAASAKRFLLAQLEEREVRELRFPASRYLGEVKLADGAAQAFYDANAAGFEQPARLKAEYVVLDEAALA
KQVKVSDEEVRAFYDGNPGRFGQPEERRARHILIQVDAGAPEAEVAKAKAAIDEIAATLAKDPGRFEALAKASSQDSGSA
ARGGDLGFFGRGAMVKPFEDAAFGQAKGVVGPVVRSDFGFHIIQVTDIKPATTRSLDSVRGEIVDELRKQAAGRRFAEVA
NDFSNMVYEQPDSLKPVAEQFGLEVRTSDWVQRGADAVGSVSSSKLVDALFAEDASKNGRNTQAIELGPNALAAGRVAAF
EPAQRLPFDQVRAEIEQQLRNEEAAKLATERGSAALAALEKGEAAGGEFSAARKLQRGAPALPAAAMQAVFAAPSGKLPA
HVGVALPEGGYAVYRIDAVNRPVLADDDPRIAAVASQYSRMVAERDFGSFLAGLRERYKVEIKLPAAPPRE

Sequences:

>Translated_631_residues
MFDAVRNNKRVAQIILALLIIPFAFFGLDAYFKDGPGGGEVAVVDGAPITAAEFDRALRERQDRLRNEMGGPVDSALLES
PALRRAVLETMVSQRLLARYAADRHMVVTPQQLQETIAAVEAFHENGQFSLQRYQDVLRAQNMTPAGFEARLAQDVRIQQ
LAASIGEAAFTPAASAKRFLLAQLEEREVRELRFPASRYLGEVKLADGAAQAFYDANAAGFEQPARLKAEYVVLDEAALA
KQVKVSDEEVRAFYDGNPGRFGQPEERRARHILIQVDAGAPEAEVAKAKAAIDEIAATLAKDPGRFEALAKASSQDSGSA
ARGGDLGFFGRGAMVKPFEDAAFGQAKGVVGPVVRSDFGFHIIQVTDIKPATTRSLDSVRGEIVDELRKQAAGRRFAEVA
NDFSNMVYEQPDSLKPVAEQFGLEVRTSDWVQRGADAVGSVSSSKLVDALFAEDASKNGRNTQAIELGPNALAAGRVAAF
EPAQRLPFDQVRAEIEQQLRNEEAAKLATERGSAALAALEKGEAAGGEFSAARKLQRGAPALPAAAMQAVFAAPSGKLPA
HVGVALPEGGYAVYRIDAVNRPVLADDDPRIAAVASQYSRMVAERDFGSFLAGLRERYKVEIKLPAAPPRE
>Mature_631_residues
MFDAVRNNKRVAQIILALLIIPFAFFGLDAYFKDGPGGGEVAVVDGAPITAAEFDRALRERQDRLRNEMGGPVDSALLES
PALRRAVLETMVSQRLLARYAADRHMVVTPQQLQETIAAVEAFHENGQFSLQRYQDVLRAQNMTPAGFEARLAQDVRIQQ
LAASIGEAAFTPAASAKRFLLAQLEEREVRELRFPASRYLGEVKLADGAAQAFYDANAAGFEQPARLKAEYVVLDEAALA
KQVKVSDEEVRAFYDGNPGRFGQPEERRARHILIQVDAGAPEAEVAKAKAAIDEIAATLAKDPGRFEALAKASSQDSGSA
ARGGDLGFFGRGAMVKPFEDAAFGQAKGVVGPVVRSDFGFHIIQVTDIKPATTRSLDSVRGEIVDELRKQAAGRRFAEVA
NDFSNMVYEQPDSLKPVAEQFGLEVRTSDWVQRGADAVGSVSSSKLVDALFAEDASKNGRNTQAIELGPNALAAGRVAAF
EPAQRLPFDQVRAEIEQQLRNEEAAKLATERGSAALAALEKGEAAGGEFSAARKLQRGAPALPAAAMQAVFAAPSGKLPA
HVGVALPEGGYAVYRIDAVNRPVLADDDPRIAAVASQYSRMVAERDFGSFLAGLRERYKVEIKLPAAPPRE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=643, Percent_Identity=25.194401244168, Blast_Score=172, Evalue=5e-44,
Organism=Escherichia coli, GI1786238, Length=135, Percent_Identity=34.0740740740741, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 67929; Mature: 67929

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDAVRNNKRVAQIILALLIIPFAFFGLDAYFKDGPGGGEVAVVDGAPITAAEFDRALRE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHH
RQDRLRNEMGGPVDSALLESPALRRAVLETMVSQRLLARYAADRHMVVTPQQLQETIAAV
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
EAFHENGQFSLQRYQDVLRAQNMTPAGFEARLAQDVRIQQLAASIGEAAFTPAASAKRFL
HHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LAQLEEREVRELRFPASRYLGEVKLADGAAQAFYDANAAGFEQPARLKAEYVVLDEAALA
HHHHHHHHHHHHCCCHHHHHCCEEECCCHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHH
KQVKVSDEEVRAFYDGNPGRFGQPEERRARHILIQVDAGAPEAEVAKAKAAIDEIAATLA
HHHCCCHHHHHHEECCCCCCCCCCHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
KDPGRFEALAKASSQDSGSAARGGDLGFFGRGAMVKPFEDAAFGQAKGVVGPVVRSDFGF
CCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHCCCCCCCHHHHHHCCCCE
HIIQVTDIKPATTRSLDSVRGEIVDELRKQAAGRRFAEVANDFSNMVYEQPDSLKPVAEQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FGLEVRTSDWVQRGADAVGSVSSSKLVDALFAEDASKNGRNTQAIELGPNALAAGRVAAF
HCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCCHHHC
EPAQRLPFDQVRAEIEQQLRNEEAAKLATERGSAALAALEKGEAAGGEFSAARKLQRGAP
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCC
ALPAAAMQAVFAAPSGKLPAHVGVALPEGGYAVYRIDAVNRPVLADDDPRIAAVASQYSR
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
MVAERDFGSFLAGLRERYKVEIKLPAAPPRE
HHHHHHHHHHHHHHHHCEEEEEECCCCCCCC
>Mature Secondary Structure
MFDAVRNNKRVAQIILALLIIPFAFFGLDAYFKDGPGGGEVAVVDGAPITAAEFDRALRE
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHH
RQDRLRNEMGGPVDSALLESPALRRAVLETMVSQRLLARYAADRHMVVTPQQLQETIAAV
HHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
EAFHENGQFSLQRYQDVLRAQNMTPAGFEARLAQDVRIQQLAASIGEAAFTPAASAKRFL
HHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LAQLEEREVRELRFPASRYLGEVKLADGAAQAFYDANAAGFEQPARLKAEYVVLDEAALA
HHHHHHHHHHHHCCCHHHHHCCEEECCCHHHHHHCCCCCCCCCCCCCCEEEEEECHHHHH
KQVKVSDEEVRAFYDGNPGRFGQPEERRARHILIQVDAGAPEAEVAKAKAAIDEIAATLA
HHHCCCHHHHHHEECCCCCCCCCCHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
KDPGRFEALAKASSQDSGSAARGGDLGFFGRGAMVKPFEDAAFGQAKGVVGPVVRSDFGF
CCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCCCCCHHHHCCCCCCCHHHHHHCCCCE
HIIQVTDIKPATTRSLDSVRGEIVDELRKQAAGRRFAEVANDFSNMVYEQPDSLKPVAEQ
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
FGLEVRTSDWVQRGADAVGSVSSSKLVDALFAEDASKNGRNTQAIELGPNALAAGRVAAF
HCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHCCHHHC
EPAQRLPFDQVRAEIEQQLRNEEAAKLATERGSAALAALEKGEAAGGEFSAARKLQRGAP
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCC
ALPAAAMQAVFAAPSGKLPAHVGVALPEGGYAVYRIDAVNRPVLADDDPRIAAVASQYSR
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHH
MVAERDFGSFLAGLRERYKVEIKLPAAPPRE
HHHHHHHHHHHHHHHHCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA