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The map label for this gene is clpB1 [H]

Identifier: 119897857

GI number: 119897857

Start: 1718010

End: 1720592

Strand: Direct

Name: clpB1 [H]

Synonym: azo1566

Alternate gene names: 119897857

Gene position: 1718010-1720592 (Clockwise)

Preceding gene: 119897855

Following gene: 119897859

Centisome position: 39.26

GC content: 66.28

Gene sequence:

>2583_bases
ATGCGTTTCGACAAGCTCACCACCAAATTCCAGCAAGCCCTCGCGGATGCCCAGAGCATCGCGGTGGGCAACGACCAGCA
GTTCATCGAGCCGCAGCACCTGCTCGCGGCGATGCTCAACCAGGACGACGGCGGCACGGTGTCGCTGTTGCAGCGCGCCG
GCGTCAATGTGCCGCCGCTGAAATCCGCGCTGCAGAAGGCGCTCGACCGCCTGCCCAAGGTGGAAGGCCATGGCGGCGAG
GTGCAGGTCGGCCGCGACCTCACCAACCTGCTCAACCTCACCGACAAGGAAGCCCAGAAGCGCGGCGACCAGTTCATCGC
CAGCGAGATGTTCCTGCTCGCGCTCGCCGACGACAAGGGCGAGACCGGCCGTCTGCTGAAGGAGCACGGCCTCACCCGCA
AGGCGCTGGAGGCGGCCGTGGATGCGGTGCGCGGCGGCCAGAACGTGGGCAGCCAGGATGCCGAAGGCCAGCGCGAGGCG
CTGAAGAAGTACTGCCTGGACCTCACCGAGCGCGCCCGCGCCGGCAAGCTCGACCCGGTGATCGGCCGTGACGACGAGAT
CCGCCGCGCGATCCAGATCCTGCAGCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCCGGCGTGGGCAAGACCG
CCATCGTCGAGGGCCTGGCGCAGCGCATCGTCAATGACGAGGTGCCGGAGACGCTCAAGGGCAAGAAGGTGCTGTCGCTC
GACATGGCGGCGCTGCTGGCCGGCGCCAAGTACCGCGGCGAGTTCGAGGAGCGGCTGAAGGCGGTGCTGAAGGACATCGC
CCAGGACGAGGGCCGCATCATCCTCTTCATCGACGAGATCCACACCATGGTGGGCGCCGGCAAGGCCGAAGGCGCGATGG
ACGCCGGCAACATGCTGAAGCCGGCGCTGGCGCGCGGCGAGCTGCACTGCATCGGCGCCACCACGCTGGACGAGTACCGC
AAGTACATCGAGAAGGATGCCGCGCTCGAACGCCGCTTCCAGAAGGTGCTGGTGGACGAGCCGACGGTGGAATCCACCAT
CGCCATCCTGCGCGGTCTGCAGGAGAAGTACGAGGTGCACCACGGCGTGGACATCACCGACCCGGCCATCGTCGCCGCGG
CGGAACTCTCGCACCGCTACATCACCGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGACGAGGCCGCGGCGCGC
ATCAAGATGGAGATCGACTCCAAGCCGGAGGTCATGGACAAGCTCGAACGCCGGCTGATCCAGCTCAAGATCGAGCAGGA
GGCGGTCAAGCGCGAGACCGACGAGGCGTCGCAGCGACGCCTGCTGCTGATCCGCGACGAGATCGACAAGCTCGAACGCG
AGTACGCCAACCTGGACGAGGTCTGGCGTTCGGAAAAGGCCAGCGTGCAGGGCAGCCAGCACATCAAGGAAGAGATCGAG
AAGCTGCGCGCGCAGATGGCCGAGATGCAGCGCAAGGGCCAGTTCGACAAGCTCGCCGAGCTGCAGTACGGCAAGCTGCC
GCAGCTGGAAGCCCAGCTGAAGGCGGCCGAAACCGCCGGCAGCGGCGAGCGCCAGTTCAAGCTCTTGCGCACCCAGGTGG
GCGCCGAGGAAATCGCCGAGGTGGTGTCTCGCGCCACCGGCATTCCGGTGAGCAAGATGATGCAGGGCGAGCGCGACAAG
CTCCTGAAGATGGAAGAGCGGCTGCACGGCCGCGTGGTGGGCCAGGACGAAGCGGTGCGGCTGGTGTCGGACGCGATCCG
GCGTTCGCGCGCGGGGCTGGCCGACGAGAACCGGCCCTACGGCTCCTTCCTCTTCCTCGGCCCCACCGGCGTGGGCAAGA
CCGAGCTGTGCAAGACGCTGGCCGAATTCCTGTTCGATTCGGAAGAGCACCTGATCCGGATCGACATGAGCGAGTTCATG
GAGAAGCACTCGGTCGCCCGCCTGATCGGCGCGCCCCCGGGCTATGTCGGCTACGAAGAAGGCGGCTACCTGACCGAGCA
GGTGCGGCGCAAGCCCTACAGCGTCATCCTGTTCGACGAGGTCGAGAAGGCACATCCGGATGTGTTCAACGTGCTGCTGC
AGGTGCTCGACGACGGCCGCATGACCGACGGCCAGGGCCGCACGGTGGACTTCAAGAACACCGTGATCGTGATGACCAGC
AACCTCGGCAGCCAGATGATCCAGCAGATGTCGGGCGACGATTACCAGGTGATCAAGCTGGCGGTGATGGCCGAGGTGAA
GACCTTCTTCCGCCCCGAGTTCATCAACCGCATCGACGAGGTGGTGGTGTTCCATGCGCTCGACGAGAAGAACATCGCCG
GTATCGCGCGCATCCAGCTGAAGTACCTGGAGAAGCGCCTGGCCAAGCTCGACATGAGCATGGAGGTGAGCGACGCGGCG
CTGGCCGAGATCGCCTCGGCCGGTTTCGATCCGGTGTTCGGCGCGCGGCCGCTGAAGCGTGCGATCCAGGAGCGCATCGA
GAATCCGCTGGCGAAGGCGATTCTCGAAGGGCAGTTCGGCGCCAAGGACCGCATCCGGGTCGACGCCAGCGGCAGCAAGC
TGAGCTTCAGCCGGGCTGACTGA

Upstream 100 bases:

>100_bases
GGGGCAGCGCGAACCCGCGGTGCGGCCCGGCGATACCGCTTGATTTCGGCCGTGCCGGCCCCATATCCGTGCCAAGCCGC
TCAGCATAAGGACGATCGTC

Downstream 100 bases:

>100_bases
GCACGGCGCATGTTGAAAGGGCGGCCCGCGGGCCGCCCTTGTCCGTTTACGCCTCTTCGGTGGCCTGCATCCAGGCTTCG
AACGCGGCCACGTCGAGCGG

Product: ATP-dependent Clp protease ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MRFDKLTTKFQQALADAQSIAVGNDQQFIEPQHLLAAMLNQDDGGTVSLLQRAGVNVPPLKSALQKALDRLPKVEGHGGE
VQVGRDLTNLLNLTDKEAQKRGDQFIASEMFLLALADDKGETGRLLKEHGLTRKALEAAVDAVRGGQNVGSQDAEGQREA
LKKYCLDLTERARAGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLKGKKVLSL
DMAALLAGAKYRGEFEERLKAVLKDIAQDEGRIILFIDEIHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPTVESTIAILRGLQEKYEVHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAR
IKMEIDSKPEVMDKLERRLIQLKIEQEAVKRETDEASQRRLLLIRDEIDKLEREYANLDEVWRSEKASVQGSQHIKEEIE
KLRAQMAEMQRKGQFDKLAELQYGKLPQLEAQLKAAETAGSGERQFKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERDK
LLKMEERLHGRVVGQDEAVRLVSDAIRRSRAGLADENRPYGSFLFLGPTGVGKTELCKTLAEFLFDSEEHLIRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILFDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTS
NLGSQMIQQMSGDDYQVIKLAVMAEVKTFFRPEFINRIDEVVVFHALDEKNIAGIARIQLKYLEKRLAKLDMSMEVSDAA
LAEIASAGFDPVFGARPLKRAIQERIENPLAKAILEGQFGAKDRIRVDASGSKLSFSRAD

Sequences:

>Translated_860_residues
MRFDKLTTKFQQALADAQSIAVGNDQQFIEPQHLLAAMLNQDDGGTVSLLQRAGVNVPPLKSALQKALDRLPKVEGHGGE
VQVGRDLTNLLNLTDKEAQKRGDQFIASEMFLLALADDKGETGRLLKEHGLTRKALEAAVDAVRGGQNVGSQDAEGQREA
LKKYCLDLTERARAGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLKGKKVLSL
DMAALLAGAKYRGEFEERLKAVLKDIAQDEGRIILFIDEIHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPTVESTIAILRGLQEKYEVHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAR
IKMEIDSKPEVMDKLERRLIQLKIEQEAVKRETDEASQRRLLLIRDEIDKLEREYANLDEVWRSEKASVQGSQHIKEEIE
KLRAQMAEMQRKGQFDKLAELQYGKLPQLEAQLKAAETAGSGERQFKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERDK
LLKMEERLHGRVVGQDEAVRLVSDAIRRSRAGLADENRPYGSFLFLGPTGVGKTELCKTLAEFLFDSEEHLIRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILFDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTS
NLGSQMIQQMSGDDYQVIKLAVMAEVKTFFRPEFINRIDEVVVFHALDEKNIAGIARIQLKYLEKRLAKLDMSMEVSDAA
LAEIASAGFDPVFGARPLKRAIQERIENPLAKAILEGQFGAKDRIRVDASGSKLSFSRAD
>Mature_860_residues
MRFDKLTTKFQQALADAQSIAVGNDQQFIEPQHLLAAMLNQDDGGTVSLLQRAGVNVPPLKSALQKALDRLPKVEGHGGE
VQVGRDLTNLLNLTDKEAQKRGDQFIASEMFLLALADDKGETGRLLKEHGLTRKALEAAVDAVRGGQNVGSQDAEGQREA
LKKYCLDLTERARAGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLKGKKVLSL
DMAALLAGAKYRGEFEERLKAVLKDIAQDEGRIILFIDEIHTMVGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYR
KYIEKDAALERRFQKVLVDEPTVESTIAILRGLQEKYEVHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAR
IKMEIDSKPEVMDKLERRLIQLKIEQEAVKRETDEASQRRLLLIRDEIDKLEREYANLDEVWRSEKASVQGSQHIKEEIE
KLRAQMAEMQRKGQFDKLAELQYGKLPQLEAQLKAAETAGSGERQFKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERDK
LLKMEERLHGRVVGQDEAVRLVSDAIRRSRAGLADENRPYGSFLFLGPTGVGKTELCKTLAEFLFDSEEHLIRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILFDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTS
NLGSQMIQQMSGDDYQVIKLAVMAEVKTFFRPEFINRIDEVVVFHALDEKNIAGIARIQLKYLEKRLAKLDMSMEVSDAA
LAEIASAGFDPVFGARPLKRAIQERIENPLAKAILEGQFGAKDRIRVDASGSKLSFSRAD

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=327, Percent_Identity=37.3088685015291, Blast_Score=216, Evalue=5e-56,
Organism=Escherichia coli, GI1788943, Length=855, Percent_Identity=66.4327485380117, Blast_Score=1162, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=399, Percent_Identity=40.6015037593985, Blast_Score=280, Evalue=2e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=707, Percent_Identity=52.0509193776521, Blast_Score=742, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=850, Percent_Identity=43.6470588235294, Blast_Score=676, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95828; Mature: 95828

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDKLTTKFQQALADAQSIAVGNDQQFIEPQHLLAAMLNQDDGGTVSLLQRAGVNVPPL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCHH
KSALQKALDRLPKVEGHGGEVQVGRDLTNLLNLTDKEAQKRGDQFIASEMFLLALADDKG
HHHHHHHHHHCCCCCCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCC
ETGRLLKEHGLTRKALEAAVDAVRGGQNVGSQDAEGQREALKKYCLDLTERARAGKLDPV
CCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLKGKKVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHH
DMAALLAGAKYRGEFEERLKAVLKDIAQDEGRIILFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPTVESTIAILRGLQEKYEVH
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAARIKMEIDSKPEVMDKLERRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
QLKIEQEAVKRETDEASQRRLLLIRDEIDKLEREYANLDEVWRSEKASVQGSQHIKEEIE
HHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
KLRAQMAEMQRKGQFDKLAELQYGKLPQLEAQLKAAETAGSGERQFKLLRTQVGAEEIAE
HHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHH
VVSRATGIPVSKMMQGERDKLLKMEERLHGRVVGQDEAVRLVSDAIRRSRAGLADENRPY
HHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFLFLGPTGVGKTELCKTLAEFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYVGYEE
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGYLTEQVRRKPYSVILFDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTS
CCCHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEEC
NLGSQMIQQMSGDDYQVIKLAVMAEVKTFFRPEFINRIDEVVVFHALDEKNIAGIARIQL
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KYLEKRLAKLDMSMEVSDAALAEIASAGFDPVFGARPLKRAIQERIENPLAKAILEGQFG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
AKDRIRVDASGSKLSFSRAD
CCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MRFDKLTTKFQQALADAQSIAVGNDQQFIEPQHLLAAMLNQDDGGTVSLLQRAGVNVPPL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCHH
KSALQKALDRLPKVEGHGGEVQVGRDLTNLLNLTDKEAQKRGDQFIASEMFLLALADDKG
HHHHHHHHHHCCCCCCCCCCEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCC
ETGRLLKEHGLTRKALEAAVDAVRGGQNVGSQDAEGQREALKKYCLDLTERARAGKLDPV
CCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLKGKKVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHCCCCHHHH
DMAALLAGAKYRGEFEERLKAVLKDIAQDEGRIILFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGELHCIGATTLDEYRKYIEKDAALERRFQKVLVDEPTVESTIAILRGLQEKYEVH
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAARIKMEIDSKPEVMDKLERRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
QLKIEQEAVKRETDEASQRRLLLIRDEIDKLEREYANLDEVWRSEKASVQGSQHIKEEIE
HHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHH
KLRAQMAEMQRKGQFDKLAELQYGKLPQLEAQLKAAETAGSGERQFKLLRTQVGAEEIAE
HHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHH
VVSRATGIPVSKMMQGERDKLLKMEERLHGRVVGQDEAVRLVSDAIRRSRAGLADENRPY
HHHHHCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFLFLGPTGVGKTELCKTLAEFLFDSEEHLIRIDMSEFMEKHSVARLIGAPPGYVGYEE
CCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGYLTEQVRRKPYSVILFDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMTS
CCCHHHHHCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEEC
NLGSQMIQQMSGDDYQVIKLAVMAEVKTFFRPEFINRIDEVVVFHALDEKNIAGIARIQL
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
KYLEKRLAKLDMSMEVSDAALAEIASAGFDPVFGARPLKRAIQERIENPLAKAILEGQFG
HHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
AKDRIRVDASGSKLSFSRAD
CCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]