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The map label for this gene is moaE [H]

Identifier: 119897855

GI number: 119897855

Start: 1716738

End: 1717208

Strand: Direct

Name: moaE [H]

Synonym: azo1564

Alternate gene names: 119897855

Gene position: 1716738-1717208 (Clockwise)

Preceding gene: 119897854

Following gene: 119897857

Centisome position: 39.23

GC content: 70.28

Gene sequence:

>471_bases
ATGTCGATCAGCGTTCAGGAAGAGGATTTCGATGTCGGCGCCGAGATCGACGCGCTGACCGCGGGCAGGGTGGATGTCGG
TGCGGTGGCGAGCTTCGTCGGCCTGGTTCGGGATGCCAACGAAGGCAGCGGTGTTTCGGCGATGACGCTGGAGCACTATC
CGGGGATGACCGAGCAGGCACTCGCGGACATCGTCGCGGAGGCCGAGGCGCGCTGGAGGCTGAACGCGGTGCGCGTGATC
CACCGCTACGGCCGGCTGGTGCCGGGCAACCGCATCGTGTTCGTCGCGGTGGCGGGGGCCCACCGTGGCGAAGCTTTCGC
CGCCTGCGAGTTCATCATGGACTACCTGAAGACGCGGGCGCCGTTCTGGAAGCGCGAGGAAACGCCGCAGGGTGCGCGCT
GGGTGGACGCGCGCGAGGGCGACGCCGCCGCAGCCGCGCGCTGGGGCACAGGCGGCGAGGGCGGGCGCTAG

Upstream 100 bases:

>100_bases
GTGCGCGCGGCGGTGAATCAGCGTATGGCCGGGCCGGAGGTGGAACTGCGCCCCGGCGATGAAGTGGCCTTTTTTCCGCC
GGTTACCGGAGGCTGAAACG

Downstream 100 bases:

>100_bases
GCGACCCGGCACGCAGCAATAAAAAAACGGCGCCCGCGGGCGCCGTTTTTTTGTCGCCGAGGCGATCTTACTTGCGCGGG
CGGGCTGCGCCGGTGAAGGC

Product: molybdenum cofactor biosynthesis protein E

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSISVQEEDFDVGAEIDALTAGRVDVGAVASFVGLVRDANEGSGVSAMTLEHYPGMTEQALADIVAEAEARWRLNAVRVI
HRYGRLVPGNRIVFVAVAGAHRGEAFAACEFIMDYLKTRAPFWKREETPQGARWVDAREGDAAAAARWGTGGEGGR

Sequences:

>Translated_156_residues
MSISVQEEDFDVGAEIDALTAGRVDVGAVASFVGLVRDANEGSGVSAMTLEHYPGMTEQALADIVAEAEARWRLNAVRVI
HRYGRLVPGNRIVFVAVAGAHRGEAFAACEFIMDYLKTRAPFWKREETPQGARWVDAREGDAAAAARWGTGGEGGR
>Mature_155_residues
SISVQEEDFDVGAEIDALTAGRVDVGAVASFVGLVRDANEGSGVSAMTLEHYPGMTEQALADIVAEAEARWRLNAVRVIH
RYGRLVPGNRIVFVAVAGAHRGEAFAACEFIMDYLKTRAPFWKREETPQGARWVDAREGDAAAAARWGTGGEGGR

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=113, Percent_Identity=30.0884955752212, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787003, Length=147, Percent_Identity=61.2244897959184, Blast_Score=172, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356259, Length=127, Percent_Identity=29.1338582677165, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 16778; Mature: 16647

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISVQEEDFDVGAEIDALTAGRVDVGAVASFVGLVRDANEGSGVSAMTLEHYPGMTEQA
CCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
LADIVAEAEARWRLNAVRVIHRYGRLVPGNRIVFVAVAGAHRGEAFAACEFIMDYLKTRA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
PFWKREETPQGARWVDAREGDAAAAARWGTGGEGGR
CCCCCCCCCCCCEEECCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SISVQEEDFDVGAEIDALTAGRVDVGAVASFVGLVRDANEGSGVSAMTLEHYPGMTEQA
CCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHH
LADIVAEAEARWRLNAVRVIHRYGRLVPGNRIVFVAVAGAHRGEAFAACEFIMDYLKTRA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCC
PFWKREETPQGARWVDAREGDAAAAARWGTGGEGGR
CCCCCCCCCCCCEEECCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]