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The map label for this gene is frlR [H]

Identifier: 119897839

GI number: 119897839

Start: 1697454

End: 1698182

Strand: Direct

Name: frlR [H]

Synonym: azo1548

Alternate gene names: 119897839

Gene position: 1697454-1698182 (Clockwise)

Preceding gene: 119897836

Following gene: 119897840

Centisome position: 38.79

GC content: 62.55

Gene sequence:

>729_bases
ATGGCTCAGGAATCCCCAACATTCAGTCCGCTCTACCGTCAGATCAAGACCTTGATTCTTCAAGCGCTTGAGGCGGGCGA
ATGGCGTCCGGGGCAGGCGATCCCGAGCGAGCAGGAACTGGCGGCGCGCTTCAGTGTATCGCAGGGTACGGTGCGAAAGG
CGATCGATGAAATGGCGGCCGAGAACCTGCTGATCCGCAAGCAGGGCAAGGGTACCTTCGTCGCCTCGCATAACGATCCG
CGTGCCCTGTTCCGTTTCTTGCGTCTCGTGCCGATGGATGGCGACCTGTCCCATCCGCAGAGCATCCCGCTCGATTGCTG
GCGCGCCAAGGCGGGGCAGGAGGCCTCGCGGATGCTCGGCATCGAGCTGGGCGCGCCCATCATCATCGTCCGCCGTCTGC
TGCGCTTCGCGATGAAGCCGGTGGTGATTGACGAAATCTATCTGCCCGGTGACGTCTTTCCCGGGCTCAGCTTCGAAATG
CTGCAGGGCTGGAATGGTTCGCTGTACAGCCTGTTCGAAACCCGCTTCGGGCTGCGCATGATCCGCGCCCAGGAGCGCAT
CCGCGCCGTTGCCGCCGACCGTTCCACGGGCGAGGCGCTGAAGGTTCCCGAGGGTACGCCGCTGCTCTCGGTGGAGCGGG
TGACCTATACCTATGGCGATAAACCGGTCGAGTGGCGCAGGGGGCTCTACTCGACCGCCGAGCACTTCTATCTCAATGAA
TTGAATTGA

Upstream 100 bases:

>100_bases
TTAGAAGCAAGCAGAACGCCTGTCAAATCATGTCTTTTGTCTTATATAAGACATATGACAGGTCATAGACGCTTCGGAAT
TTTTGTGATCAAATATGTGT

Downstream 100 bases:

>100_bases
ATGTGCCGGATGCATGCGGTCCGGTTCGGGTCGCTATAATCAAGAGCTTTTGGGAGTCAGCGACGGATGGCCGTCGCACA
TGTTGAGGGGAGTCTTCATG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAQESPTFSPLYRQIKTLILQALEAGEWRPGQAIPSEQELAARFSVSQGTVRKAIDEMAAENLLIRKQGKGTFVASHNDP
RALFRFLRLVPMDGDLSHPQSIPLDCWRAKAGQEASRMLGIELGAPIIIVRRLLRFAMKPVVIDEIYLPGDVFPGLSFEM
LQGWNGSLYSLFETRFGLRMIRAQERIRAVAADRSTGEALKVPEGTPLLSVERVTYTYGDKPVEWRRGLYSTAEHFYLNE
LN

Sequences:

>Translated_242_residues
MAQESPTFSPLYRQIKTLILQALEAGEWRPGQAIPSEQELAARFSVSQGTVRKAIDEMAAENLLIRKQGKGTFVASHNDP
RALFRFLRLVPMDGDLSHPQSIPLDCWRAKAGQEASRMLGIELGAPIIIVRRLLRFAMKPVVIDEIYLPGDVFPGLSFEM
LQGWNGSLYSLFETRFGLRMIRAQERIRAVAADRSTGEALKVPEGTPLLSVERVTYTYGDKPVEWRRGLYSTAEHFYLNE
LN
>Mature_241_residues
AQESPTFSPLYRQIKTLILQALEAGEWRPGQAIPSEQELAARFSVSQGTVRKAIDEMAAENLLIRKQGKGTFVASHNDPR
ALFRFLRLVPMDGDLSHPQSIPLDCWRAKAGQEASRMLGIELGAPIIIVRRLLRFAMKPVVIDEIYLPGDVFPGLSFEML
QGWNGSLYSLFETRFGLRMIRAQERIRAVAADRSTGEALKVPEGTPLLSVERVTYTYGDKPVEWRRGLYSTAEHFYLNEL
N

Specific function: May regulate the transcription of the frlABCD operon [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082252, Length=217, Percent_Identity=30.4147465437788, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790118, Length=210, Percent_Identity=27.1428571428571, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790540, Length=227, Percent_Identity=31.2775330396476, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=24.6808510638298, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788418, Length=222, Percent_Identity=22.972972972973, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27294; Mature: 27163

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQESPTFSPLYRQIKTLILQALEAGEWRPGQAIPSEQELAARFSVSQGTVRKAIDEMAA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
ENLLIRKQGKGTFVASHNDPRALFRFLRLVPMDGDLSHPQSIPLDCWRAKAGQEASRMLG
HCEEEEECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHH
IELGAPIIIVRRLLRFAMKPVVIDEIYLPGDVFPGLSFEMLQGWNGSLYSLFETRFGLRM
HHCCCHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
IRAQERIRAVAADRSTGEALKVPEGTPLLSVERVTYTYGDKPVEWRRGLYSTAEHFYLNE
HHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHEECC
LN
CC
>Mature Secondary Structure 
AQESPTFSPLYRQIKTLILQALEAGEWRPGQAIPSEQELAARFSVSQGTVRKAIDEMAA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHH
ENLLIRKQGKGTFVASHNDPRALFRFLRLVPMDGDLSHPQSIPLDCWRAKAGQEASRMLG
HCEEEEECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHH
IELGAPIIIVRRLLRFAMKPVVIDEIYLPGDVFPGLSFEMLQGWNGSLYSLFETRFGLRM
HHCCCHHHHHHHHHHHHHCCHHEEEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
IRAQERIRAVAADRSTGEALKVPEGTPLLSVERVTYTYGDKPVEWRRGLYSTAEHFYLNE
HHHHHHHHHHHHCCCCCCEEECCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHHHEECC
LN
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]