Click here to switch to the map view.

The map label for this gene is divJ [H]

Identifier: 119897783

GI number: 119897783

Start: 1630684

End: 1632525

Strand: Reverse

Name: divJ [H]

Synonym: azo1492

Alternate gene names: 119897783

Gene position: 1632525-1630684 (Counterclockwise)

Preceding gene: 119897784

Following gene: 119897782

Centisome position: 37.31

GC content: 66.99

Gene sequence:

>1842_bases
ATGACGGTAGATGTATGCAGACTGATGCAGGATGAATCGCCCGACGCCTGCATCGTGCTCGACGCCGACGGCGCAGTGCG
CCACTGGAACGGCGGCGCAGTACGCCTGTTCGGCTATAACGCGGCGGAGGCCGATGGCCAGCTCCTGATCGACCTGACCG
TGCCGCCGGACCGACGCGCGGCGGAACAGGCGCTGCTCGACGATCTGCCCCCGCTCGGCAACGCAACGCACGAGTCGGTC
CGCCAGCGCAAGGACGGCTCGCTGGTGCATGTGGCGCTGTCGATGAGGCGGGTTCATGCCGACGGCCTCCCGTATGTGCT
GACGAGCATGAAGGACGTCACCCAGCTCAAGGTGGCGCGCGAAGCGCGGCTGGTCGAGACGCGCTACCGCGACCTGCTGG
AATCGATGCCCGACGGCATCGTGATGGTGAACGCGCTCGGCCGCATCGTCTTTTCCAATCAGCAGGCTGACGCGATGTTC
GGCTACGGCGCGGGCGAACTGCGCGGTCAGCCGATCGAGGCGCTGCTGCCGGCGCGGCTGCGCACCGCGCACGTGGGCCA
CCGCAGCCACTACTTCGGCCAACCGCGCACGCGGACCATGGGCATGGGGCTGGAACTCTTCGGCCTGCGCCACGATGGCA
GCGAGTTTCCGCTCGAAATCAGCCTCAGTCCGCTACATACCGACGAAGGCACGATGGTGCTGAGCGCCATCCGCGACATC
GCCGGCCGCAAGAAGGCCGAGGAGAAGTTCCGCGGCCTGCTCGAATCGGCGCCGGATGCGATCGTCATCGTCAACCGCGA
CGGACGCATCGTGCTGGTCAATTCACAGGCGGAGCGCCTGTTCGGCTATGCGCGCAGCGAGCTGATCGATCAGCAGATCG
AGATGCTGATGCCCGAACGCTTTCGCGCCCAGCACCCCGGGCACCGCAACAGCTTCTTCACCGACCCGCGGGTGCGGCCG
ATGGGCGTCGGGCTGGAACTGTTCGGACGCCGCCGCAACGGCGAGGAGTTCCCGGTGGAGATCAGCCTCAGTCCGCTCGA
AACCGAAGAAGGCACGCTGGTGTCGAGCGCGATCCGCGACATCACCGAGCGCAAGCGCTTCGAACGCGCGCTGCAGGAAA
AGAACGTGGAACTGGCGCAGGCCAATGCCGCCAAGGACCACTTCCTCGCCAGCATGAGCCATGAGCTGCGCACGCCGCTG
AACGCCATCATCGGCTTCACCGGCACGCTGCTGATGAAGCTGCCGGGTCCGCTCAACGAAGACCAGGAGAAGCAGCTGCG
CACCGTGCAGCGCAGCGCCAGCCACCTGCTGTCGCTGATCAACGACCTGCTCGACGTCGCCCGCATCGAGGCCGGCAAGT
TCGAGCCCGTGTTCGAGCCGGTGGACCTCTGCGCCACCCTCGAGGAACTGGCCGTCGTCCTGCGCCCGCAGGCCGAGGCC
AAGGGCCTGCGGCTCGAGCTGAAGCTGCCCGGTGGTTCCTGCGTGGTCGAAACCGACCAGCGCGCATTCAGTCAGATTGT
CATCAACCTGCTGCAGAACGCGATCAAGTTCACGGAGCACGGCCGCATCGAGCTTGCGCTTGCCCGTATCGAAGCGGACG
GTCGGCCCGCGGTCGAGTTGCAGGTCGCCGACAGCGGCATCGGCATCCAGCCAGACGACCAGACGCGGCTCTTCGCGCCC
TTCGCCCGCATCACCCCGGCAGCGGGGCCGGCGCAGGAAGGGACGGGGCTGGGCCTGCACCTTTGCCTCAAGCTCGCCGC
GCAGCTCGGCGGCCAGATCGCAATGCACAGCACCTATGGCGAGGGCAGCGTGTTCTCGCTGATCTTGCCGGAGCAGCCAT
GA

Upstream 100 bases:

>100_bases
AGCGGACCATCGCAGCCGCTGTTTTTTCGTCGAATGCCGCCTTCCGCCGGCGCACCGGCCGTCGCCGGCCCCATGGAAGA
CGGACCGGAACGGAGCAGGC

Downstream 100 bases:

>100_bases
TGGGCGCGCGCATCCTCGTCGCCGAAGACAACCTCGCCAACCTGGAACTGGTGCGCTACCTGCTAAGCCGTGCAGGGCAC
GAGGTCATCACCACGGCCGA

Product: putative histidine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 613; Mature: 612

Protein sequence:

>613_residues
MTVDVCRLMQDESPDACIVLDADGAVRHWNGGAVRLFGYNAAEADGQLLIDLTVPPDRRAAEQALLDDLPPLGNATHESV
RQRKDGSLVHVALSMRRVHADGLPYVLTSMKDVTQLKVAREARLVETRYRDLLESMPDGIVMVNALGRIVFSNQQADAMF
GYGAGELRGQPIEALLPARLRTAHVGHRSHYFGQPRTRTMGMGLELFGLRHDGSEFPLEISLSPLHTDEGTMVLSAIRDI
AGRKKAEEKFRGLLESAPDAIVIVNRDGRIVLVNSQAERLFGYARSELIDQQIEMLMPERFRAQHPGHRNSFFTDPRVRP
MGVGLELFGRRRNGEEFPVEISLSPLETEEGTLVSSAIRDITERKRFERALQEKNVELAQANAAKDHFLASMSHELRTPL
NAIIGFTGTLLMKLPGPLNEDQEKQLRTVQRSASHLLSLINDLLDVARIEAGKFEPVFEPVDLCATLEELAVVLRPQAEA
KGLRLELKLPGGSCVVETDQRAFSQIVINLLQNAIKFTEHGRIELALARIEADGRPAVELQVADSGIGIQPDDQTRLFAP
FARITPAAGPAQEGTGLGLHLCLKLAAQLGGQIAMHSTYGEGSVFSLILPEQP

Sequences:

>Translated_613_residues
MTVDVCRLMQDESPDACIVLDADGAVRHWNGGAVRLFGYNAAEADGQLLIDLTVPPDRRAAEQALLDDLPPLGNATHESV
RQRKDGSLVHVALSMRRVHADGLPYVLTSMKDVTQLKVAREARLVETRYRDLLESMPDGIVMVNALGRIVFSNQQADAMF
GYGAGELRGQPIEALLPARLRTAHVGHRSHYFGQPRTRTMGMGLELFGLRHDGSEFPLEISLSPLHTDEGTMVLSAIRDI
AGRKKAEEKFRGLLESAPDAIVIVNRDGRIVLVNSQAERLFGYARSELIDQQIEMLMPERFRAQHPGHRNSFFTDPRVRP
MGVGLELFGRRRNGEEFPVEISLSPLETEEGTLVSSAIRDITERKRFERALQEKNVELAQANAAKDHFLASMSHELRTPL
NAIIGFTGTLLMKLPGPLNEDQEKQLRTVQRSASHLLSLINDLLDVARIEAGKFEPVFEPVDLCATLEELAVVLRPQAEA
KGLRLELKLPGGSCVVETDQRAFSQIVINLLQNAIKFTEHGRIELALARIEADGRPAVELQVADSGIGIQPDDQTRLFAP
FARITPAAGPAQEGTGLGLHLCLKLAAQLGGQIAMHSTYGEGSVFSLILPEQP
>Mature_612_residues
TVDVCRLMQDESPDACIVLDADGAVRHWNGGAVRLFGYNAAEADGQLLIDLTVPPDRRAAEQALLDDLPPLGNATHESVR
QRKDGSLVHVALSMRRVHADGLPYVLTSMKDVTQLKVAREARLVETRYRDLLESMPDGIVMVNALGRIVFSNQQADAMFG
YGAGELRGQPIEALLPARLRTAHVGHRSHYFGQPRTRTMGMGLELFGLRHDGSEFPLEISLSPLHTDEGTMVLSAIRDIA
GRKKAEEKFRGLLESAPDAIVIVNRDGRIVLVNSQAERLFGYARSELIDQQIEMLMPERFRAQHPGHRNSFFTDPRVRPM
GVGLELFGRRRNGEEFPVEISLSPLETEEGTLVSSAIRDITERKRFERALQEKNVELAQANAAKDHFLASMSHELRTPLN
AIIGFTGTLLMKLPGPLNEDQEKQLRTVQRSASHLLSLINDLLDVARIEAGKFEPVFEPVDLCATLEELAVVLRPQAEAK
GLRLELKLPGGSCVVETDQRAFSQIVINLLQNAIKFTEHGRIELALARIEADGRPAVELQVADSGIGIQPDDQTRLFAPF
ARITPAAGPAQEGTGLGLHLCLKLAAQLGGQIAMHSTYGEGSVFSLILPEQP

Specific function: Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn r

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with divK (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=368, Percent_Identity=33.1521739130435, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789149, Length=274, Percent_Identity=38.3211678832117, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1788713, Length=397, Percent_Identity=27.7078085642317, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI145693157, Length=256, Percent_Identity=36.328125, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=38.5892116182573, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788549, Length=371, Percent_Identity=26.1455525606469, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI1786600, Length=370, Percent_Identity=26.4864864864865, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=29.2576419213974, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=31.9634703196347, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=228, Percent_Identity=28.5087719298246, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=281, Percent_Identity=26.3345195729537, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=287, Percent_Identity=26.1324041811847, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081921, Length=247, Percent_Identity=25.9109311740891, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=249, Percent_Identity=28.5140562248996, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67469; Mature: 67338

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVDVCRLMQDESPDACIVLDADGAVRHWNGGAVRLFGYNAAEADGQLLIDLTVPPDRRA
CCHHHHHHHCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCCCCCEEEEEEECCCCHHH
AEQALLDDLPPLGNATHESVRQRKDGSLVHVALSMRRVHADGLPYVLTSMKDVTQLKVAR
HHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EARLVETRYRDLLESMPDGIVMVNALGRIVFSNQQADAMFGYGAGELRGQPIEALLPARL
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHEECCCCCCCEECCCCHHCCCCCHHHHHHHHH
RTAHVGHRSHYFGQPRTRTMGMGLELFGLRHDGSEFPLEISLSPLHTDEGTMVLSAIRDI
HHHHCCCCHHCCCCCCCEEECCCEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHH
AGRKKAEEKFRGLLESAPDAIVIVNRDGRIVLVNSQAERLFGYARSELIDQQIEMLMPER
HCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHH
FRAQHPGHRNSFFTDPRVRPMGVGLELFGRRRNGEEFPVEISLSPLETEEGTLVSSAIRD
HHHCCCCCCCCCCCCCCCCEECCCHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
ITERKRFERALQEKNVELAQANAAKDHFLASMSHELRTPLNAIIGFTGTLLMKLPGPLNE
HHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHEEEECCCCCCC
DQEKQLRTVQRSASHLLSLINDLLDVARIEAGKFEPVFEPVDLCATLEELAVVLRPQAEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
KGLRLELKLPGGSCVVETDQRAFSQIVINLLQNAIKFTEHGRIELALARIEADGRPAVEL
CCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEE
QVADSGIGIQPDDQTRLFAPFARITPAAGPAQEGTGLGLHLCLKLAAQLGGQIAMHSTYG
EEECCCCCCCCCCCCEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECC
EGSVFSLILPEQP
CCCEEEEECCCCC
>Mature Secondary Structure 
TVDVCRLMQDESPDACIVLDADGAVRHWNGGAVRLFGYNAAEADGQLLIDLTVPPDRRA
CHHHHHHHCCCCCCEEEEECCCCCEEECCCCEEEEEECCCCCCCCEEEEEEECCCCHHH
AEQALLDDLPPLGNATHESVRQRKDGSLVHVALSMRRVHADGLPYVLTSMKDVTQLKVAR
HHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHH
EARLVETRYRDLLESMPDGIVMVNALGRIVFSNQQADAMFGYGAGELRGQPIEALLPARL
HHHHHHHHHHHHHHHCCCCEEEEEHHHHHEECCCCCCCEECCCCHHCCCCCHHHHHHHHH
RTAHVGHRSHYFGQPRTRTMGMGLELFGLRHDGSEFPLEISLSPLHTDEGTMVLSAIRDI
HHHHCCCCHHCCCCCCCEEECCCEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHH
AGRKKAEEKFRGLLESAPDAIVIVNRDGRIVLVNSQAERLFGYARSELIDQQIEMLMPER
HCCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCHH
FRAQHPGHRNSFFTDPRVRPMGVGLELFGRRRNGEEFPVEISLSPLETEEGTLVSSAIRD
HHHCCCCCCCCCCCCCCCCEECCCHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
ITERKRFERALQEKNVELAQANAAKDHFLASMSHELRTPLNAIIGFTGTLLMKLPGPLNE
HHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHEEEECCCCCCC
DQEKQLRTVQRSASHLLSLINDLLDVARIEAGKFEPVFEPVDLCATLEELAVVLRPQAEA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
KGLRLELKLPGGSCVVETDQRAFSQIVINLLQNAIKFTEHGRIELALARIEADGRPAVEL
CCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEE
QVADSGIGIQPDDQTRLFAPFARITPAAGPAQEGTGLGLHLCLKLAAQLGGQIAMHSTYG
EEECCCCCCCCCCCCEEECCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEECC
EGSVFSLILPEQP
CCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA