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The map label for this gene is truC [H]

Identifier: 119897756

GI number: 119897756

Start: 1598208

End: 1598990

Strand: Reverse

Name: truC [H]

Synonym: azo1465

Alternate gene names: 119897756

Gene position: 1598990-1598208 (Counterclockwise)

Preceding gene: 119897757

Following gene: 119897755

Centisome position: 36.54

GC content: 68.71

Gene sequence:

>783_bases
GTGCTCGAGATCCTTTATCAAGACGAACACCTCGTCGCCATCCACAAGCCCTCCGGGCTGCTGGTACACCGCAGCGCGCT
CGACGCGCACGAGGAACGCTTCGCGGTGCAACTGCTGCGCGACCAGCTCGGCCGCCACGTGCACCCGGTACACCGTCTCG
ACAAAGGCACTTCGGGCGTGCTCGTGTTCGCGCTCGACCGCGACACCGCCGGACGGCTCGCGACGCAGTTCGAAACCCGC
GCCGTGCGCAAGCAGTATGTCGCCATCGTGCGCGGTCATCCGGCCGAGGCGGGCACGATCGACCATCCGCTGAGCCGCCG
CTTCGACCCGGTCGAGCACGTCGCCGAGGACAAGGTCTTCGCGCCGCAGCCCGCGATCACCCGTTTCCGCCGCCTCGCAA
CCGCAGAGCTGCCCTGGGCGGTCGACCGCTATCCCACCAGCCGCTACGCGCTGCTCGCGCTGGAACCGGAAACCGGGCGC
CGCCACCAGATCAGGCGGCACCTGAAGCACATCTCCCACCCCATCATCGGCGACTCGACCTTCGGCAAGGGCAAGCACAA
TCGCATGTTCCAGGCGCACTTCGGCAGCGAACGGATGCTGCTCGCCTGCACCGACATCGAACTGCGCCATCCGCAGCGCG
ACGCGCCGCTGCAGCTGCATGCTGCCCCCGCGCCAGACTTCCGCGCGGTCGCCGACGCACTCGGCTGGCATGACGCGCTG
GCGCGCCTTCCGGCCGACGGGGATACGGGGCACAATGCGTGTTTCCCCGAATCCACCCGCTAA

Upstream 100 bases:

>100_bases
GCGCAGAACTTCGCCTGATCCCGCCTGCCTCGCGGGTGCACGCACCCGCGGCAGCAAAAGCGACCCGACCGGGTCGCTTT
TTCTTTTTCCACTCCCGCCC

Downstream 100 bases:

>100_bases
GTTCCGCGCCGCCATGAAACCGCTGCTCCAGGTCCGCCAGCACGGCCAGCAAGTCTGGCTCGACAACCTCTCCCGTACCC
TGCTCAACGACGGCCACCTG

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA pseudouridylate synthase C; tRNA-uridine isomerase C [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLEILYQDEHLVAIHKPSGLLVHRSALDAHEERFAVQLLRDQLGRHVHPVHRLDKGTSGVLVFALDRDTAGRLATQFETR
AVRKQYVAIVRGHPAEAGTIDHPLSRRFDPVEHVAEDKVFAPQPAITRFRRLATAELPWAVDRYPTSRYALLALEPETGR
RHQIRRHLKHISHPIIGDSTFGKGKHNRMFQAHFGSERMLLACTDIELRHPQRDAPLQLHAAPAPDFRAVADALGWHDAL
ARLPADGDTGHNACFPESTR

Sequences:

>Translated_260_residues
MLEILYQDEHLVAIHKPSGLLVHRSALDAHEERFAVQLLRDQLGRHVHPVHRLDKGTSGVLVFALDRDTAGRLATQFETR
AVRKQYVAIVRGHPAEAGTIDHPLSRRFDPVEHVAEDKVFAPQPAITRFRRLATAELPWAVDRYPTSRYALLALEPETGR
RHQIRRHLKHISHPIIGDSTFGKGKHNRMFQAHFGSERMLLACTDIELRHPQRDAPLQLHAAPAPDFRAVADALGWHDAL
ARLPADGDTGHNACFPESTR
>Mature_260_residues
MLEILYQDEHLVAIHKPSGLLVHRSALDAHEERFAVQLLRDQLGRHVHPVHRLDKGTSGVLVFALDRDTAGRLATQFETR
AVRKQYVAIVRGHPAEAGTIDHPLSRRFDPVEHVAEDKVFAPQPAITRFRRLATAELPWAVDRYPTSRYALLALEPETGR
RHQIRRHLKHISHPIIGDSTFGKGKHNRMFQAHFGSERMLLACTDIELRHPQRDAPLQLHAAPAPDFRAVADALGWHDAL
ARLPADGDTGHNACFPESTR

Specific function: Responsible for synthesis of pseudouridine from uracil- 65 in transfer RNAs [H]

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yqcC in the N-terminal section [H]

Homologues:

Organism=Homo sapiens, GI221316663, Length=193, Percent_Identity=34.1968911917098, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI221316667, Length=184, Percent_Identity=35.8695652173913, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI23308689, Length=190, Percent_Identity=30.5263157894737, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI17158025, Length=150, Percent_Identity=34.6666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1789155, Length=242, Percent_Identity=48.7603305785124, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1786244, Length=213, Percent_Identity=35.2112676056338, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788946, Length=263, Percent_Identity=29.6577946768061, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1787327, Length=224, Percent_Identity=29.4642857142857, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324506, Length=186, Percent_Identity=31.7204301075269, Blast_Score=88, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320168, Length=184, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6321608, Length=191, Percent_Identity=29.3193717277487, Blast_Score=75, Evalue=9e-15,
Organism=Drosophila melanogaster, GI19921090, Length=183, Percent_Identity=27.3224043715847, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24583449, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583447, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583445, Length=186, Percent_Identity=26.3440860215054, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007384
- InterPro:   IPR020103
- InterPro:   IPR006224
- InterPro:   IPR006145 [H]

Pfam domain/function: PF04287 DUF446; PF00849 PseudoU_synth_2 [H]

EC number: NA

Molecular weight: Translated: 29331; Mature: 29331

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS01129 PSI_RLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEILYQDEHLVAIHKPSGLLVHRSALDAHEERFAVQLLRDQLGRHVHPVHRLDKGTSGV
CEEEEEECCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCE
LVFALDRDTAGRLATQFETRAVRKQYVAIVRGHPAEAGTIDHPLSRRFDPVEHVAEDKVF
EEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHCCCHHHHHHCCCCC
APQPAITRFRRLATAELPWAVDRYPTSRYALLALEPETGRRHQIRRHLKHISHPIIGDST
CCCHHHHHHHHHHHCCCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
FGKGKHNRMFQAHFGSERMLLACTDIELRHPQRDAPLQLHAAPAPDFRAVADALGWHDAL
CCCCCCCCEEEEECCCCEEEEEEECCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ARLPADGDTGHNACFPESTR
HHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLEILYQDEHLVAIHKPSGLLVHRSALDAHEERFAVQLLRDQLGRHVHPVHRLDKGTSGV
CEEEEEECCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCE
LVFALDRDTAGRLATQFETRAVRKQYVAIVRGHPAEAGTIDHPLSRRFDPVEHVAEDKVF
EEEEECCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHCCCHHHHHHCCCCC
APQPAITRFRRLATAELPWAVDRYPTSRYALLALEPETGRRHQIRRHLKHISHPIIGDST
CCCHHHHHHHHHHHCCCCCHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
FGKGKHNRMFQAHFGSERMLLACTDIELRHPQRDAPLQLHAAPAPDFRAVADALGWHDAL
CCCCCCCCEEEEECCCCEEEEEEECCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ARLPADGDTGHNACFPESTR
HHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA