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The map label for this gene is yafV [C]

Identifier: 119897586

GI number: 119897586

Start: 1410696

End: 1411553

Strand: Direct

Name: yafV [C]

Synonym: azo1295

Alternate gene names: 119897586

Gene position: 1410696-1411553 (Clockwise)

Preceding gene: 119897585

Following gene: 119897587

Centisome position: 32.24

GC content: 69.11

Gene sequence:

>858_bases
ATGAATTCCTCCTCGCCACGCTCCGCCCCTCAGACTGCGCGTCCTCCGGTACGGGTGGCGGCGGTGCAGACCGTATCGGG
TCCAGACGTCGCGGCCAATCTGCGGGTTGTTGCCGAACTGGTTGCCGCTGCCGCGGACGACGGCGCGAAGCTCGTCGCGC
TGCCTGAGTATTTCGCATTGATCAGCGCCGTCGAGACCGACAAGGTGCGTCTGCGGGAGCGTGACGGCGAAGGGCCCTTG
CAGCACTTCCTGCGTGAAACCGCGGCCCGCCACCGGGTGTGGCTGGTCGGCGGAACGGTACCGCTGGTCGCAGCGAGCGA
CCAGAAGGTGCGCAATACCACCCTGGTGTACGACGACCGCGGCGAACGCGTCGCCCGCTACGACAAGATCCACCTGTTCG
GCTTCCAGCGTGGTGCTGAGCGCTACGACGAGGCGGCCACCATCGAGCCCGGGCGGGAAGTCGTGTGTTTCGACAGCCCG
GCCGGCCGCACCGGCCTTTCGGTGTGCTACGACCTGCGCTTCCCCGAGCTTTTCCGCGCCATGGCCGAGCCCGACCTGAT
CGTGCTGCCCGCCGCCTTTACCCACACCACCGGGCGTGCGCACTGGGAGGTGCTGCTGCGGGCGCGGGCGATCGAAAACC
AGTGCTATGTAATGGCGCCGGCACAGGGCGGCTGCCACCCGAGCGGGCGCGTGACCTGGGGCCACTCGATGATCGTCGAC
CCCTGGGGTGAAATCCTCGCATGCCGCGAGGAAGGGCCCGGCTTCGTCGCTGCCGATCTCCACCCCGAGCGCATCGCCAG
CGTACGCGCCAGCCTGCCGGCGCTGGAACACCGCTGCCTGCCGGGCGCGGCTTCGTGA

Upstream 100 bases:

>100_bases
GGGACGATCCCAAGGTGGAAAAACTGGGCTCGCCCGCCGAGAACCTGATTCCCCAACTACCGCGCGCGCAGCCCGCTCCG
CGTTCAGGCTCTACTGCCCC

Downstream 100 bases:

>100_bases
ACGCGGTTCGACACCGATCGTTTTCCTTCGCGCCGGGTCCAACCCGGCGAACGCCAGTTGCGGATTCCACATGAGCAAAT
CGACCAATCCCCTGAAGATC

Product: carbon-nitrogen hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MNSSSPRSAPQTARPPVRVAAVQTVSGPDVAANLRVVAELVAAAADDGAKLVALPEYFALISAVETDKVRLRERDGEGPL
QHFLRETAARHRVWLVGGTVPLVAASDQKVRNTTLVYDDRGERVARYDKIHLFGFQRGAERYDEAATIEPGREVVCFDSP
AGRTGLSVCYDLRFPELFRAMAEPDLIVLPAAFTHTTGRAHWEVLLRARAIENQCYVMAPAQGGCHPSGRVTWGHSMIVD
PWGEILACREEGPGFVAADLHPERIASVRASLPALEHRCLPGAAS

Sequences:

>Translated_285_residues
MNSSSPRSAPQTARPPVRVAAVQTVSGPDVAANLRVVAELVAAAADDGAKLVALPEYFALISAVETDKVRLRERDGEGPL
QHFLRETAARHRVWLVGGTVPLVAASDQKVRNTTLVYDDRGERVARYDKIHLFGFQRGAERYDEAATIEPGREVVCFDSP
AGRTGLSVCYDLRFPELFRAMAEPDLIVLPAAFTHTTGRAHWEVLLRARAIENQCYVMAPAQGGCHPSGRVTWGHSMIVD
PWGEILACREEGPGFVAADLHPERIASVRASLPALEHRCLPGAAS
>Mature_285_residues
MNSSSPRSAPQTARPPVRVAAVQTVSGPDVAANLRVVAELVAAAADDGAKLVALPEYFALISAVETDKVRLRERDGEGPL
QHFLRETAARHRVWLVGGTVPLVAASDQKVRNTTLVYDDRGERVARYDKIHLFGFQRGAERYDEAATIEPGREVVCFDSP
AGRTGLSVCYDLRFPELFRAMAEPDLIVLPAAFTHTTGRAHWEVLLRARAIENQCYVMAPAQGGCHPSGRVTWGHSMIVD
PWGEILACREEGPGFVAADLHPERIASVRASLPALEHRCLPGAAS

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI5031947, Length=267, Percent_Identity=40.0749063670412, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI297632350, Length=267, Percent_Identity=40.0749063670412, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI297632348, Length=267, Percent_Identity=40.0749063670412, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI9910460, Length=264, Percent_Identity=34.8484848484849, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI297632346, Length=192, Percent_Identity=35.4166666666667, Blast_Score=97, Evalue=1e-20,
Organism=Escherichia coli, GI1786412, Length=230, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=265, Percent_Identity=37.3584905660377, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6323383, Length=282, Percent_Identity=34.0425531914894, Blast_Score=162, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6322335, Length=298, Percent_Identity=33.2214765100671, Blast_Score=155, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17933642, Length=269, Percent_Identity=40.1486988847584, Blast_Score=185, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21355835, Length=268, Percent_Identity=32.089552238806, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30978; Mature: 30978

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSSSPRSAPQTARPPVRVAAVQTVSGPDVAANLRVVAELVAAAADDGAKLVALPEYFAL
CCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHHHHH
ISAVETDKVRLRERDGEGPLQHFLRETAARHRVWLVGGTVPLVAASDQKVRNTTLVYDDR
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHCEEEEEECCEEEEECCCCCCCCEEEEECCC
GERVARYDKIHLFGFQRGAERYDEAATIEPGREVVCFDSPAGRTGLSVCYDLRFPELFRA
CCEEHHHEEEEEEEEHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHH
MAEPDLIVLPAAFTHTTGRAHWEVLLRARAIENQCYVMAPAQGGCHPSGRVTWGHSMIVD
HCCCCEEEEECHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCEEEC
PWGEILACREEGPGFVAADLHPERIASVRASLPALEHRCLPGAAS
CCCCEEEEECCCCCEEEECCCHHHHHHHHHHCHHHHHHCCCCCCC
>Mature Secondary Structure
MNSSSPRSAPQTARPPVRVAAVQTVSGPDVAANLRVVAELVAAAADDGAKLVALPEYFAL
CCCCCCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECHHHHHH
ISAVETDKVRLRERDGEGPLQHFLRETAARHRVWLVGGTVPLVAASDQKVRNTTLVYDDR
HHHHCCCCEEEEECCCCCHHHHHHHHHHHHCEEEEEECCEEEEECCCCCCCCEEEEECCC
GERVARYDKIHLFGFQRGAERYDEAATIEPGREVVCFDSPAGRTGLSVCYDLRFPELFRA
CCEEHHHEEEEEEEEHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHH
MAEPDLIVLPAAFTHTTGRAHWEVLLRARAIENQCYVMAPAQGGCHPSGRVTWGHSMIVD
HCCCCEEEEECHHCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCEEEC
PWGEILACREEGPGFVAADLHPERIASVRASLPALEHRCLPGAAS
CCCCEEEEECCCCCEEEECCCHHHHHHHHHHCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]