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The map label for this gene is gdhAlpha1

Identifier: 119897519

GI number: 119897519

Start: 1321992

End: 1323557

Strand: Direct

Name: gdhAlpha1

Synonym: azo1228

Alternate gene names: NA

Gene position: 1321992-1323557 (Clockwise)

Preceding gene: 119897518

Following gene: 119897520

Centisome position: 30.21

GC content: 66.86

Gene sequence:

>1566_bases
ATGGCAACCTACAAGCACGACGACAATTCGGTAGTGGTCATCATCGGCTCCGGCGCGGGCGGCGGCACGCTGGCCAACGA
GCTGTGCCAGAAGGGCATCAAGGTGGTGGTGCTGGAAGCCGGCAAGCGCCAGTCGCCGGCCACCTTCATCAATGACGAGT
GGGCCGCCTTCGGCCAGCTGTCGTGGACCGACAAGCGCACCACCTCCGGCAGCTGGCGGGTGGCGAAGGACTTTCCCAAC
CTGCCGGCGTGGATCTGCAAGACGGTGGGCGGCACCACCACCCACTGGGCGGGCGCCTCGCTGCGCTTCCAGGAGCACGA
GTTCCGTACCCGCACGGTGTACGGCGACATCGCCGGCGCCAACCTGCTCGACTGGCCGCTGACGCTGGCCGAGCTGGAGC
CGTACTACGCCCGTGCCGAGGACAAGATGGGCGTGACCCGCACCCACGACATCCCGGGGCTGCCCGGCAACAACAACTTC
AAGGTGTTCTACAACGGCGCCACCAAGATGGGCTACGGCGCCACCACCGGCCGCATGGCGATCAACAGCGAACCGCGCGC
CGGACGCGGCTCCTGCCAGCAGTACGGGTTCTGTTTCCAGGGCTGCAAGAGCGGCGCCAAGTGGTCCACGCTGTACACCG
AGATTCCCGCCGCCGAGAAGACCGGCAAGCTGGAACTGCGCACCGAGTGCCATGTGGCGCGCATCGAGCACGATGCCGCC
GGCAAGGCCACCGGCGTGGTGTATTTCGACAAGGACGGCAAGGAGCAGCGCCAGAAGGCGCGCGTGGTGTGCGTGGCGGG
CAACGCCATCGAAACGCCGCGCCTGCTGCTGATGTCCGCGTCCAGCAAGTTCCCGGACGGCCTCGCCAACTCCTCCGGCC
AGGTGGGGCGCAACTACATGCGCCACACCACCGGCTCGGTGTATGCCACCTTCAACGACCCGGTGCACATGTACCGCGGC
ACCACCATGGCCGGCATCGTGCAGGACGAGGCCCACCACAACACCAAGCGCGGCTTCGCCGGCGGCTACGAGCTGGAGAC
GCTGTCGCTCGGCCTGCCCTTCATGGCGGCCTTCCTCAACCCCGGCGGCTGGGGCAAGGACTTTGCCGAGGCGATGGACA
ACTACGTCAACATGGCCGGGCTGTGGATCGTCGGCGAGGACATGCCGCAGGAAACCAACCGCGTCACGCTGCACGCCACC
GAGAAGGACCAGTGGGGGCTGCCGGTGCCCAATGTGCATTACGACGACCACCCCAACGACATCGCGCTGCGCAAGCACGC
CTACCAGCAGGCCAGCGCGCTGTATCAGTCGGTGGGGGCGAAAAAGGTGTACGAGGTGCCGCCTTATCCCTCCACCCACA
ACCTCGGCACCTGCCGCATGAGCGCCAAGGCGAGCGACGGCGTGCTGAACAAGTGGGGCCAGACGCACGACATCAAGAAC
CTGTTCGTCTCCGACGGCAGCCAGTACACGACCGGCGCAACGGAAAACCCGACGCTGACCATCGTGACGCTGGCGATCCG
CCAGGCGGACTACATTGCCGGGCAGATGCAGGCGCGGGCGCTCTGA

Upstream 100 bases:

>100_bases
CTGCGCGGCTTCAACGACCTGAAGTGGCTGCCGAACCCGAGCGCCCAGGCCAGCCCGGCGCCGTTCGGCGCCTGACCCCG
CATCCGAGGACAAGAACATC

Downstream 100 bases:

>100_bases
GCGCACCCGCCGGGCGGCGCGTCCGTTTCATGCCGGGCGCGCCGCCTCAAGGGATTGCCCCCTCACCGGGGTAGTGCATC
TCCCTCCTTGGCGCCGGGTC

Product: putative glucose dehydrogenase subunit alpha

Products: NA

Alternate protein names: GA 2-DH dehydrogenase subunit; GADH dehydrogenase subunit [H]

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MATYKHDDNSVVVIIGSGAGGGTLANELCQKGIKVVVLEAGKRQSPATFINDEWAAFGQLSWTDKRTTSGSWRVAKDFPN
LPAWICKTVGGTTTHWAGASLRFQEHEFRTRTVYGDIAGANLLDWPLTLAELEPYYARAEDKMGVTRTHDIPGLPGNNNF
KVFYNGATKMGYGATTGRMAINSEPRAGRGSCQQYGFCFQGCKSGAKWSTLYTEIPAAEKTGKLELRTECHVARIEHDAA
GKATGVVYFDKDGKEQRQKARVVCVAGNAIETPRLLLMSASSKFPDGLANSSGQVGRNYMRHTTGSVYATFNDPVHMYRG
TTMAGIVQDEAHHNTKRGFAGGYELETLSLGLPFMAAFLNPGGWGKDFAEAMDNYVNMAGLWIVGEDMPQETNRVTLHAT
EKDQWGLPVPNVHYDDHPNDIALRKHAYQQASALYQSVGAKKVYEVPPYPSTHNLGTCRMSAKASDGVLNKWGQTHDIKN
LFVSDGSQYTTGATENPTLTIVTLAIRQADYIAGQMQARAL

Sequences:

>Translated_521_residues
MATYKHDDNSVVVIIGSGAGGGTLANELCQKGIKVVVLEAGKRQSPATFINDEWAAFGQLSWTDKRTTSGSWRVAKDFPN
LPAWICKTVGGTTTHWAGASLRFQEHEFRTRTVYGDIAGANLLDWPLTLAELEPYYARAEDKMGVTRTHDIPGLPGNNNF
KVFYNGATKMGYGATTGRMAINSEPRAGRGSCQQYGFCFQGCKSGAKWSTLYTEIPAAEKTGKLELRTECHVARIEHDAA
GKATGVVYFDKDGKEQRQKARVVCVAGNAIETPRLLLMSASSKFPDGLANSSGQVGRNYMRHTTGSVYATFNDPVHMYRG
TTMAGIVQDEAHHNTKRGFAGGYELETLSLGLPFMAAFLNPGGWGKDFAEAMDNYVNMAGLWIVGEDMPQETNRVTLHAT
EKDQWGLPVPNVHYDDHPNDIALRKHAYQQASALYQSVGAKKVYEVPPYPSTHNLGTCRMSAKASDGVLNKWGQTHDIKN
LFVSDGSQYTTGATENPTLTIVTLAIRQADYIAGQMQARAL
>Mature_520_residues
ATYKHDDNSVVVIIGSGAGGGTLANELCQKGIKVVVLEAGKRQSPATFINDEWAAFGQLSWTDKRTTSGSWRVAKDFPNL
PAWICKTVGGTTTHWAGASLRFQEHEFRTRTVYGDIAGANLLDWPLTLAELEPYYARAEDKMGVTRTHDIPGLPGNNNFK
VFYNGATKMGYGATTGRMAINSEPRAGRGSCQQYGFCFQGCKSGAKWSTLYTEIPAAEKTGKLELRTECHVARIEHDAAG
KATGVVYFDKDGKEQRQKARVVCVAGNAIETPRLLLMSASSKFPDGLANSSGQVGRNYMRHTTGSVYATFNDPVHMYRGT
TMAGIVQDEAHHNTKRGFAGGYELETLSLGLPFMAAFLNPGGWGKDFAEAMDNYVNMAGLWIVGEDMPQETNRVTLHATE
KDQWGLPVPNVHYDDHPNDIALRKHAYQQASALYQSVGAKKVYEVPPYPSTHNLGTCRMSAKASDGVLNKWGQTHDIKNL
FVSDGSQYTTGATENPTLTIVTLAIRQADYIAGQMQARAL

Specific function: Part of the heterotrimer that catalyzes the conversion of D-gluconate to 2-dehydro-D-gluconate. This subunit functions as the dehydrogenase [H]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.3 [H]

Molecular weight: Translated: 56930; Mature: 56798

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYKHDDNSVVVIIGSGAGGGTLANELCQKGIKVVVLEAGKRQSPATFINDEWAAFGQL
CCCEEECCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHCCCE
SWTDKRTTSGSWRVAKDFPNLPAWICKTVGGTTTHWAGASLRFQEHEFRTRTVYGDIAGA
ECCCCCCCCCCEEECCCCCCCHHHHHHHCCCCEEECCCCEEEEECCCCEEEEEEECCCCC
NLLDWPLTLAELEPYYARAEDKMGVTRTHDIPGLPGNNNFKVFYNGATKMGYGATTGRMA
CEECCCEEHHHCCCHHHCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCEE
INSEPRAGRGSCQQYGFCFQGCKSGAKWSTLYTEIPAAEKTGKLELRTECHVARIEHDAA
ECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEECEEEEEECCCCC
GKATGVVYFDKDGKEQRQKARVVCVAGNAIETPRLLLMSASSKFPDGLANSSGQVGRNYM
CCEEEEEEECCCCHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
RHTTGSVYATFNDPVHMYRGTTMAGIVQDEAHHNTKRGFAGGYELETLSLGLPFMAAFLN
HCCCCCEEEEECCCEEEECCCEEEEEEECHHCCCCCCCCCCCEEEEEEECCHHHHHHHCC
PGGWGKDFAEAMDNYVNMAGLWIVGEDMPQETNRVTLHATEKDQWGLPVPNVHYDDHPND
CCCCCHHHHHHHHHHHCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
IALRKHAYQQASALYQSVGAKKVYEVPPYPSTHNLGTCRMSAKASDGVLNKWGQTHDIKN
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCHH
LFVSDGSQYTTGATENPTLTIVTLAIRQADYIAGQMQARAL
HEECCCCEEECCCCCCCCEEEEEEEEHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATYKHDDNSVVVIIGSGAGGGTLANELCQKGIKVVVLEAGKRQSPATFINDEWAAFGQL
CCEEECCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCEEECCCCHHCCCE
SWTDKRTTSGSWRVAKDFPNLPAWICKTVGGTTTHWAGASLRFQEHEFRTRTVYGDIAGA
ECCCCCCCCCCEEECCCCCCCHHHHHHHCCCCEEECCCCEEEEECCCCEEEEEEECCCCC
NLLDWPLTLAELEPYYARAEDKMGVTRTHDIPGLPGNNNFKVFYNGATKMGYGATTGRMA
CEECCCEEHHHCCCHHHCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCEE
INSEPRAGRGSCQQYGFCFQGCKSGAKWSTLYTEIPAAEKTGKLELRTECHVARIEHDAA
ECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEECEEEEEECCCCC
GKATGVVYFDKDGKEQRQKARVVCVAGNAIETPRLLLMSASSKFPDGLANSSGQVGRNYM
CCEEEEEEECCCCHHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
RHTTGSVYATFNDPVHMYRGTTMAGIVQDEAHHNTKRGFAGGYELETLSLGLPFMAAFLN
HCCCCCEEEEECCCEEEECCCEEEEEEECHHCCCCCCCCCCCEEEEEEECCHHHHHHHCC
PGGWGKDFAEAMDNYVNMAGLWIVGEDMPQETNRVTLHATEKDQWGLPVPNVHYDDHPND
CCCCCHHHHHHHHHHHCEEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCC
IALRKHAYQQASALYQSVGAKKVYEVPPYPSTHNLGTCRMSAKASDGVLNKWGQTHDIKN
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEEECCCCCCHHHHCCCCCCCHH
LFVSDGSQYTTGATENPTLTIVTLAIRQADYIAGQMQARAL
HEECCCCEEECCCCCCCCEEEEEEEEHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9352901 [H]