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The map label for this gene is mphP [H]

Identifier: 119897511

GI number: 119897511

Start: 1313496

End: 1314539

Strand: Direct

Name: mphP [H]

Synonym: azo1220

Alternate gene names: 119897511

Gene position: 1313496-1314539 (Clockwise)

Preceding gene: 119897510

Following gene: 119897512

Centisome position: 30.02

GC content: 66.76

Gene sequence:

>1044_bases
ATGTCCGAAACCCCTGTACACATCGTCCGGTTCGAGCCGGTCGGCGTCGAGATGGAGGTCGCCGAAGGCGAAACCGTGCT
CGACGCGGCCTTTCGCCAGGGCGTGGCCGTCATGCACGGCTGCAAGGAAGGGCAGTGCAGCAGCTGCAAGGCGCTGCTGA
TCGACGGCGACGTCGAGATGCTCAAGTACTCCACCTTCGCGCTGCCCGACTACGAGCGCGACGCCAACCACGTGCTGCTG
TGCCGCACGCTGGCGCACACCGACATCACGGTGGAACTGCTCAACTACGACGAAGACCTGATGCGGCGCTCGATCGCGGT
CAAGGAGTTCGCCGGCAAGGTGGTCGGCATCAGCGCGCTGACCCACGACATCCGCAGGCTCGACGTCGAGCTGGAACAGC
CGATCCGCTTCTGGGCCGGCCAGTTCGTCGACATCACGCTGCCGGAAAAGGGCATCACCCGCTCGTACTCGATGGCGAGC
GTGCCGAGCAGCCCCGGCCAGGTGTCCTTCATCATCAAGAAGTACCCCAACGGCGCGTTCTCCACCGCGCTCGACACCGA
GCTGAAGCCGGGCGATCCGGTGCTGGTGAAGGGCCCCTACGGCGGCTGTTTCCGCCGCGAGGAACGCCCCGGCCCGATGG
TGCTGATCGGCGGCGGCTCCGGCATGTCGCCGCTGTGGTCCATCCTCAACGACCACATCGAAAGCGGCGAGCAGCGCCCG
ATCCGCTTCTTCTACGGTGCCCGCACCCGGCGCGACCTGTTCTACCTGGAGCAGTTCGCCGAGTTCGAGCAGAAGGTGCC
CGACTTCCGCTTCATCCCGGCGCTGTCGGCGGCCGAGCCGGAAGACGGCTGGACCGGCGAGACCGGCTACATCCACGAGG
TGGTGGCGCGCACGCTGAAGGAAGAAGGCTTCGACGGCGCCTCGATCGACGCCTACACCTGCGGCCCCGCGCCGATGATC
GACGCGATCACCCCGGTGCTGCACATGGCCGGCGTGCCGCCCGACCAGATGTACTTCGACAAATTCACCCAGGCCGTGCG
CTGA

Upstream 100 bases:

>100_bases
GATCAACCCGTTCCAGTAAAGCCTCTGCGCGGGTGCGCGTCCGCCTGGCGGCGCGCGCCCGCGGTTCCCGGCCCATGCAC
ATGAAATAAGGAAGACCAGC

Downstream 100 bases:

>100_bases
AGGCCCGGGCCGCAGCCCCCACCCGCCGCACCCACCCACAAGCAAGGAAGACCAGGAGACTCACGTGAACGCATTCACCC
AGGAAGCCGTCGCCCAGCCC

Product: aromatic/alkene monooxygenase subunit gamma

Products: NA

Alternate protein names: Phenol 2-monooxygenase P5 component [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSETPVHIVRFEPVGVEMEVAEGETVLDAAFRQGVAVMHGCKEGQCSSCKALLIDGDVEMLKYSTFALPDYERDANHVLL
CRTLAHTDITVELLNYDEDLMRRSIAVKEFAGKVVGISALTHDIRRLDVELEQPIRFWAGQFVDITLPEKGITRSYSMAS
VPSSPGQVSFIIKKYPNGAFSTALDTELKPGDPVLVKGPYGGCFRREERPGPMVLIGGGSGMSPLWSILNDHIESGEQRP
IRFFYGARTRRDLFYLEQFAEFEQKVPDFRFIPALSAAEPEDGWTGETGYIHEVVARTLKEEGFDGASIDAYTCGPAPMI
DAITPVLHMAGVPPDQMYFDKFTQAVR

Sequences:

>Translated_347_residues
MSETPVHIVRFEPVGVEMEVAEGETVLDAAFRQGVAVMHGCKEGQCSSCKALLIDGDVEMLKYSTFALPDYERDANHVLL
CRTLAHTDITVELLNYDEDLMRRSIAVKEFAGKVVGISALTHDIRRLDVELEQPIRFWAGQFVDITLPEKGITRSYSMAS
VPSSPGQVSFIIKKYPNGAFSTALDTELKPGDPVLVKGPYGGCFRREERPGPMVLIGGGSGMSPLWSILNDHIESGEQRP
IRFFYGARTRRDLFYLEQFAEFEQKVPDFRFIPALSAAEPEDGWTGETGYIHEVVARTLKEEGFDGASIDAYTCGPAPMI
DAITPVLHMAGVPPDQMYFDKFTQAVR
>Mature_346_residues
SETPVHIVRFEPVGVEMEVAEGETVLDAAFRQGVAVMHGCKEGQCSSCKALLIDGDVEMLKYSTFALPDYERDANHVLLC
RTLAHTDITVELLNYDEDLMRRSIAVKEFAGKVVGISALTHDIRRLDVELEQPIRFWAGQFVDITLPEKGITRSYSMASV
PSSPGQVSFIIKKYPNGAFSTALDTELKPGDPVLVKGPYGGCFRREERPGPMVLIGGGSGMSPLWSILNDHIESGEQRPI
RFFYGARTRRDLFYLEQFAEFEQKVPDFRFIPALSAAEPEDGWTGETGYIHEVVARTLKEEGFDGASIDAYTCGPAPMID
AITPVLHMAGVPPDQMYFDKFTQAVR

Specific function: Probable electron transfer from NADPH, via FAD and the 2Fe-2S center, to the oxygenase activity site of the enzyme [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI84875541, Length=268, Percent_Identity=25, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI2367314, Length=207, Percent_Identity=28.0193236714976, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787658, Length=223, Percent_Identity=24.2152466367713, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322146, Length=178, Percent_Identity=28.0898876404494, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323552, Length=183, Percent_Identity=26.775956284153, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323510, Length=185, Percent_Identity=29.1891891891892, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322699, Length=221, Percent_Identity=23.5294117647059, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: =1.14.13.7 [H]

Molecular weight: Translated: 38508; Mature: 38377

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETPVHIVRFEPVGVEMEVAEGETVLDAAFRQGVAVMHGCKEGQCSSCKALLIDGDVEM
CCCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEECCHHE
LKYSTFALPDYERDANHVLLCRTLAHTDITVELLNYDEDLMRRSIAVKEFAGKVVGISAL
EEEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEHHHH
THDIRRLDVELEQPIRFWAGQFVDITLPEKGITRSYSMASVPSSPGQVSFIIKKYPNGAF
HHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCC
STALDTELKPGDPVLVKGPYGGCFRREERPGPMVLIGGGSGMSPLWSILNDHIESGEQRP
CHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
IRFFYGARTRRDLFYLEQFAEFEQKVPDFRFIPALSAAEPEDGWTGETGYIHEVVARTLK
EEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
EEGFDGASIDAYTCGPAPMIDAITPVLHMAGVPPDQMYFDKFTQAVR
HCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SETPVHIVRFEPVGVEMEVAEGETVLDAAFRQGVAVMHGCKEGQCSSCKALLIDGDVEM
CCCCEEEEEECCCCEEEEECCCCHHHHHHHHCCHHHHHCCCCCCCCCCEEEEEECCHHE
LKYSTFALPDYERDANHVLLCRTLAHTDITVELLNYDEDLMRRSIAVKEFAGKVVGISAL
EEEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHCCCEEEHHHH
THDIRRLDVELEQPIRFWAGQFVDITLPEKGITRSYSMASVPSSPGQVSFIIKKYPNGAF
HHHHHHHCCCHHHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCCEEEEEEEECCCCCC
STALDTELKPGDPVLVKGPYGGCFRREERPGPMVLIGGGSGMSPLWSILNDHIESGEQRP
CHHCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCC
IRFFYGARTRRDLFYLEQFAEFEQKVPDFRFIPALSAAEPEDGWTGETGYIHEVVARTLK
EEEEECCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH
EEGFDGASIDAYTCGPAPMIDAITPVLHMAGVPPDQMYFDKFTQAVR
HCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12732969 [H]