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The map label for this gene is cobW [H]

Identifier: 119897501

GI number: 119897501

Start: 1303298

End: 1304290

Strand: Direct

Name: cobW [H]

Synonym: azo1210

Alternate gene names: 119897501

Gene position: 1303298-1304290 (Clockwise)

Preceding gene: 119897500

Following gene: 119897502

Centisome position: 29.78

GC content: 71.5

Gene sequence:

>993_bases
ATGAACGCCGCGCCAAGCCGCCTGCCGGTCACGGTGCTCACCGGCTTTCTCGGCGCGGGCAAGACCACGCTGCTCAACCA
CCTGCTGCGCGAAAGCGGCGGCCGCTACGCGGTCATCGTCAATGAGTACGGCGAGATCGGCATCGACGGCGAACTGGTGG
TGGGGGCCGAGGAAGAGGTGCTGGAACTCAACAACGGCTGCATCTGCTGCAAGGTGCGCGGCGACCTGATCCGCGTGGTC
AGTGGCCTGCTCAAGCGCCGCGGCCGCTTCGACGGCATCCTGATCGAGACCACCGGCCTCGCCGACCCCGCGCCGGTCGT
GCAGTCCTTCATGGCCGACGACGAGATCCGCCAGCAGGCCCGGGTCGATGGCGTGGTCTGCGTGGTCGATGCCTGCCACT
TCCTCACCGGCCTGGAACGCAGCCGCGAGGCGGGCGTGCAGCTGGCCCACGCCAGCCTGGTGGTCATCAACAAGGCGGAA
CTGGCCGACGAGGCGGTGGTGGCGCAGGTGGAGCGCGAGATCGCGCGCCTCAACCCCGGCGCCACGGTGCTGCGCAGCGC
GCGCGGCGCGGTGCCGGCCGCGGCGCTGCTGGACCAGGGCGCCTACGAGCTGCCGCGGCTGGAACTGCCCGCCGCGCCTG
CTGCCGCCCGCGCGCGCTACGTGCCGGTGCCGCAGGGGCGCCATACCGACGGCCTCGCGTGCGTGTCGCTGGTGTTGCAG
CGTCCGCTGGAGCGCGGCCGCTTCCTCGCCTGGCTGCAGCGCCTGGTCACCGAGCGTGGCGAAAAGCTGCTGCGCACCAA
GGGCATCGTTGCGCTCGCCGGCGCGGACCGCCGCTTCGTCTTCCAGGGCGTCCACATGATGGTCGATAGCGATTTCGACC
GCCCGTGGCGCACCGAGGAGACGCGCGACAGCCGGCTGGTGTTCATCGGCCACGGGCTGGACGACAGCGAACTGCGCGCC
GGTCTCGACGCCTGCCAGGTCTCGCCGGCATGA

Upstream 100 bases:

>100_bases
AGGCGGAGGCCGAGCTGGACGCGCTGGACGACCAGCGCACCCAGCTGCTTGTTGTGCTCGATGCCCTGAACGCCGCCGAA
GCCGGCCCCGGAGCCCTGCA

Downstream 100 bases:

>100_bases
ACGCGCCACTGGGGGGCTTGCCGCCGCTGGTGGCGCTGTGCGGCGCGCACTGGCGCCTGGAGGCGCCGGTGGTCGCGGTG
GCGTGGTCGCGCCGCGGTGG

Product: putative GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNAAPSRLPVTVLTGFLGAGKTTLLNHLLRESGGRYAVIVNEYGEIGIDGELVVGAEEEVLELNNGCICCKVRGDLIRVV
SGLLKRRGRFDGILIETTGLADPAPVVQSFMADDEIRQQARVDGVVCVVDACHFLTGLERSREAGVQLAHASLVVINKAE
LADEAVVAQVEREIARLNPGATVLRSARGAVPAAALLDQGAYELPRLELPAAPAAARARYVPVPQGRHTDGLACVSLVLQ
RPLERGRFLAWLQRLVTERGEKLLRTKGIVALAGADRRFVFQGVHMMVDSDFDRPWRTEETRDSRLVFIGHGLDDSELRA
GLDACQVSPA

Sequences:

>Translated_330_residues
MNAAPSRLPVTVLTGFLGAGKTTLLNHLLRESGGRYAVIVNEYGEIGIDGELVVGAEEEVLELNNGCICCKVRGDLIRVV
SGLLKRRGRFDGILIETTGLADPAPVVQSFMADDEIRQQARVDGVVCVVDACHFLTGLERSREAGVQLAHASLVVINKAE
LADEAVVAQVEREIARLNPGATVLRSARGAVPAAALLDQGAYELPRLELPAAPAAARARYVPVPQGRHTDGLACVSLVLQ
RPLERGRFLAWLQRLVTERGEKLLRTKGIVALAGADRRFVFQGVHMMVDSDFDRPWRTEETRDSRLVFIGHGLDDSELRA
GLDACQVSPA
>Mature_330_residues
MNAAPSRLPVTVLTGFLGAGKTTLLNHLLRESGGRYAVIVNEYGEIGIDGELVVGAEEEVLELNNGCICCKVRGDLIRVV
SGLLKRRGRFDGILIETTGLADPAPVVQSFMADDEIRQQARVDGVVCVVDACHFLTGLERSREAGVQLAHASLVVINKAE
LADEAVVAQVEREIARLNPGATVLRSARGAVPAAALLDQGAYELPRLELPAAPAAARARYVPVPQGRHTDGLACVSLVLQ
RPLERGRFLAWLQRLVTERGEKLLRTKGIVALAGADRRFVFQGVHMMVDSDFDRPWRTEETRDSRLVFIGHGLDDSELRA
GLDACQVSPA

Specific function: Might be involved in cobalt reduction leading to cobalt(I) corrinoids [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI148727351, Length=335, Percent_Identity=32.8358208955224, Blast_Score=178, Evalue=6e-45,
Organism=Homo sapiens, GI146231952, Length=335, Percent_Identity=32.5373134328358, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI33469141, Length=335, Percent_Identity=32.5373134328358, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI126722884, Length=335, Percent_Identity=32.5373134328358, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI223941779, Length=335, Percent_Identity=31.044776119403, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI223941776, Length=324, Percent_Identity=32.0987654320988, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI119120938, Length=329, Percent_Identity=29.483282674772, Blast_Score=144, Evalue=2e-34,
Organism=Escherichia coli, GI87082430, Length=320, Percent_Identity=33.75, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1788499, Length=239, Percent_Identity=32.2175732217573, Blast_Score=94, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324356, Length=227, Percent_Identity=30.8370044052863, Blast_Score=119, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012824
- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 35681; Mature: 35681

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAPSRLPVTVLTGFLGAGKTTLLNHLLRESGGRYAVIVNEYGEIGIDGELVVGAEEEV
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCHHHH
LELNNGCICCKVRGDLIRVVSGLLKRRGRFDGILIETTGLADPAPVVQSFMADDEIRQQA
HCCCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHH
RVDGVVCVVDACHFLTGLERSREAGVQLAHASLVVINKAELADEAVVAQVEREIARLNPG
HHCCEEHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCC
ATVLRSARGAVPAAALLDQGAYELPRLELPAAPAAARARYVPVPQGRHTDGLACVSLVLQ
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCHHHCCEECCCCCCCCCCHHHHHHHHHH
RPLERGRFLAWLQRLVTERGEKLLRTKGIVALAGADRRFVFQGVHMMVDSDFDRPWRTEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHEEECCCCCCCCCCC
TRDSRLVFIGHGLDDSELRAGLDACQVSPA
CCCCEEEEEECCCCHHHHHHCCHHHCCCCC
>Mature Secondary Structure
MNAAPSRLPVTVLTGFLGAGKTTLLNHLLRESGGRYAVIVNEYGEIGIDGELVVGAEEEV
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCHHHH
LELNNGCICCKVRGDLIRVVSGLLKRRGRFDGILIETTGLADPAPVVQSFMADDEIRQQA
HCCCCCEEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHH
RVDGVVCVVDACHFLTGLERSREAGVQLAHASLVVINKAELADEAVVAQVEREIARLNPG
HHCCEEHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCC
ATVLRSARGAVPAAALLDQGAYELPRLELPAAPAAARARYVPVPQGRHTDGLACVSLVLQ
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCHHHCCEECCCCCCCCCCHHHHHHHHHH
RPLERGRFLAWLQRLVTERGEKLLRTKGIVALAGADRRFVFQGVHMMVDSDFDRPWRTEE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHEEECCCCCCCCCCC
TRDSRLVFIGHGLDDSELRAGLDACQVSPA
CCCCEEEEEECCCCHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]