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The map label for this gene is argD [H]

Identifier: 119897486

GI number: 119897486

Start: 1287319

End: 1288497

Strand: Direct

Name: argD [H]

Synonym: azo1195

Alternate gene names: 119897486

Gene position: 1287319-1288497 (Clockwise)

Preceding gene: 119897485

Following gene: 119897492

Centisome position: 29.42

GC content: 68.53

Gene sequence:

>1179_bases
ATGAAGTACGGCGAATTCGATTCCGCTTCCCTGATGTACATCACCAACCGGCCGGAGATCCTGTTCGAGCGCGGCGAAGG
CTCCTGGCTGTACGACGCCCAGGGCAAGGCCTATCTCGACTTCGTGCAGGGCTGGGCGGTGAACTGTCTCGGCCATTCGC
CCGCCGAGGTGCGCGACGCGATCGTCGCCCAGGCGGGCAAGCTGATCAATCCGAGCCCGGCCTTCTACAACGGCCCGATG
ATCGAACTCGCCGGCCTGCTGACCGCGCACTGTTCGCTCGACCGTGTGTTCTTCGCCAACACCGGCGCCGAGGCCAACGA
AGGCGCGATCAAGCTGGCGCGCAAGTGGGGTCGCCTGCATCGCAACGGCGCCTATCAGATCATCACCTTCGAGCATTCCT
TCCACGGCCGCACGCTGGCGACCATGTCGGCGTCCGGCAAGGCGGGCTGGGACACGCTGTTCGCGCCGCAGGTACCGGGC
TTCCCCAAGGCCAGGCTCAACGATCTCGAATCGGTGAAGGCGCTGATCGGCCCGGAAACCGTGGCGGTGATGCTGGAGCC
GGTGCAGGGCGAGGGCGGCGTGATTCCCGCTGCACCGGAATTCCTGCAGGCGCTGCGCGCGCTCACCCGCGAGCACGGCA
TCCTGCTGATCGTCGATGAAGTGCAATCCGGCATGGGCCGCACCGGCCGCCTGTTCGCGCACCAGCACGCCGGCATCGAG
CCGGACATCATGACCCTGGGCAAGGGCATTGGCGGCGGCGTGCCACTGTCGGCGCTGCTGGCGACCGAGGCGGTGAGCTG
CTTCGAGGCGGGCGACCAGGGTGGCACCTACAACGGCAACCCGTTGATGACGGCGGCCGGCATTGCCGTGATGCGCCGCC
TGACCGCGCCCGGCTTCCTCGACGAGGTGCTGGCGCGCGGCGACTACCTGGCGGCGCGGCTGCGCGAACTGGTGGCCAAG
CGCCATCTGGTCGGCGAGCGTGGCTCGGGCCTGCTGCGCGCCTTGGTGCTCGACAGCGACCGCGCTCCGGCCATCGTCAA
GGCGGCGCTTGAAGGTGCCCCCACCGGCCTGCTGCTGAACGCCCCCCGGCCCAACCTGCTGCGCTTCATGCCGTCGCTGA
CGGTGAGCGAGGCGGAGATCGACCAGATGGTGGAGATGCTGGACGCGCTGCTGGGCTGA

Upstream 100 bases:

>100_bases
CATGCCGGCAGCGGGCACGCGCCCGCGACACCGCGCTAGCATTGCGGCGCGCGGGACGCCCCGGCGCGCCTTCTTCCATC
CAGATTTTCGGAGTGTCCGC

Downstream 100 bases:

>100_bases
CGTGCTTCGTCACCCGACGGCGGTGTGGTTTGCCCCCTCCCCTTCAAGGGGAGGGCCGGGGTGGGGATGGGGTCGGCCGC
GGCGCCGACTTAACCCCATC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MKYGEFDSASLMYITNRPEILFERGEGSWLYDAQGKAYLDFVQGWAVNCLGHSPAEVRDAIVAQAGKLINPSPAFYNGPM
IELAGLLTAHCSLDRVFFANTGAEANEGAIKLARKWGRLHRNGAYQIITFEHSFHGRTLATMSASGKAGWDTLFAPQVPG
FPKARLNDLESVKALIGPETVAVMLEPVQGEGGVIPAAPEFLQALRALTREHGILLIVDEVQSGMGRTGRLFAHQHAGIE
PDIMTLGKGIGGGVPLSALLATEAVSCFEAGDQGGTYNGNPLMTAAGIAVMRRLTAPGFLDEVLARGDYLAARLRELVAK
RHLVGERGSGLLRALVLDSDRAPAIVKAALEGAPTGLLLNAPRPNLLRFMPSLTVSEAEIDQMVEMLDALLG

Sequences:

>Translated_392_residues
MKYGEFDSASLMYITNRPEILFERGEGSWLYDAQGKAYLDFVQGWAVNCLGHSPAEVRDAIVAQAGKLINPSPAFYNGPM
IELAGLLTAHCSLDRVFFANTGAEANEGAIKLARKWGRLHRNGAYQIITFEHSFHGRTLATMSASGKAGWDTLFAPQVPG
FPKARLNDLESVKALIGPETVAVMLEPVQGEGGVIPAAPEFLQALRALTREHGILLIVDEVQSGMGRTGRLFAHQHAGIE
PDIMTLGKGIGGGVPLSALLATEAVSCFEAGDQGGTYNGNPLMTAAGIAVMRRLTAPGFLDEVLARGDYLAARLRELVAK
RHLVGERGSGLLRALVLDSDRAPAIVKAALEGAPTGLLLNAPRPNLLRFMPSLTVSEAEIDQMVEMLDALLG
>Mature_392_residues
MKYGEFDSASLMYITNRPEILFERGEGSWLYDAQGKAYLDFVQGWAVNCLGHSPAEVRDAIVAQAGKLINPSPAFYNGPM
IELAGLLTAHCSLDRVFFANTGAEANEGAIKLARKWGRLHRNGAYQIITFEHSFHGRTLATMSASGKAGWDTLFAPQVPG
FPKARLNDLESVKALIGPETVAVMLEPVQGEGGVIPAAPEFLQALRALTREHGILLIVDEVQSGMGRTGRLFAHQHAGIE
PDIMTLGKGIGGGVPLSALLATEAVSCFEAGDQGGTYNGNPLMTAAGIAVMRRLTAPGFLDEVLARGDYLAARLRELVAK
RHLVGERGSGLLRALVLDSDRAPAIVKAALEGAPTGLLLNAPRPNLLRFMPSLTVSEAEIDQMVEMLDALLG

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=34.0369393139842, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=34.8993288590604, Blast_Score=165, Evalue=7e-41,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=27.7647058823529, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI24119277, Length=407, Percent_Identity=29.7297297297297, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI37574042, Length=409, Percent_Identity=29.5843520782396, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI226442705, Length=409, Percent_Identity=29.0953545232274, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI226442709, Length=383, Percent_Identity=29.7650130548303, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI188536080, Length=430, Percent_Identity=23.7209302325581, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679950, Length=430, Percent_Identity=23.7209302325581, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI38679946, Length=430, Percent_Identity=23.7209302325581, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1788044, Length=361, Percent_Identity=45.1523545706371, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1789759, Length=367, Percent_Identity=40.0544959128065, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.1658291457286, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI145693181, Length=328, Percent_Identity=35.3658536585366, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786349, Length=309, Percent_Identity=35.2750809061489, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=32.8395061728395, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786991, Length=342, Percent_Identity=33.0409356725146, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=374, Percent_Identity=33.9572192513369, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI25144274, Length=273, Percent_Identity=34.0659340659341, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71992977, Length=437, Percent_Identity=30.2059496567506, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI32564660, Length=427, Percent_Identity=27.6346604215457, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=27.5626423690205, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71981843, Length=159, Percent_Identity=32.7044025157233, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=385, Percent_Identity=34.2857142857143, Blast_Score=216, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6323470, Length=390, Percent_Identity=34.8717948717949, Blast_Score=205, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6321456, Length=419, Percent_Identity=24.8210023866348, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6324386, Length=274, Percent_Identity=26.6423357664234, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21357415, Length=374, Percent_Identity=33.6898395721925, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI28574759, Length=427, Percent_Identity=27.1662763466042, Blast_Score=135, Evalue=5e-32,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=27.1028037383178, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=27.2093023255814, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281366494, Length=429, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24667139, Length=429, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24667143, Length=429, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41879; Mature: 41879

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYGEFDSASLMYITNRPEILFERGEGSWLYDAQGKAYLDFVQGWAVNCLGHSPAEVRDA
CCCCCCCCCEEEEEECCCEEEEECCCCCEEEECCCCHHHHHHHCHHEEECCCCHHHHHHH
IVAQAGKLINPSPAFYNGPMIELAGLLTAHCSLDRVFFANTGAEANEGAIKLARKWGRLH
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
RNGAYQIITFEHSFHGRTLATMSASGKAGWDTLFAPQVPGFPKARLNDLESVKALIGPET
CCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
VAVMLEPVQGEGGVIPAAPEFLQALRALTREHGILLIVDEVQSGMGRTGRLFAHQHAGIE
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEEHHCCCCC
PDIMTLGKGIGGGVPLSALLATEAVSCFEAGDQGGTYNGNPLMTAAGIAVMRRLTAPGFL
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
DEVLARGDYLAARLRELVAKRHLVGERGSGLLRALVLDSDRAPAIVKAALEGAPTGLLLN
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCEEEE
APRPNLLRFMPSLTVSEAEIDQMVEMLDALLG
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKYGEFDSASLMYITNRPEILFERGEGSWLYDAQGKAYLDFVQGWAVNCLGHSPAEVRDA
CCCCCCCCCEEEEEECCCEEEEECCCCCEEEECCCCHHHHHHHCHHEEECCCCHHHHHHH
IVAQAGKLINPSPAFYNGPMIELAGLLTAHCSLDRVFFANTGAEANEGAIKLARKWGRLH
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHH
RNGAYQIITFEHSFHGRTLATMSASGKAGWDTLFAPQVPGFPKARLNDLESVKALIGPET
CCCCEEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCE
VAVMLEPVQGEGGVIPAAPEFLQALRALTREHGILLIVDEVQSGMGRTGRLFAHQHAGIE
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEEHHHCCCCCCCEEEEHHCCCCC
PDIMTLGKGIGGGVPLSALLATEAVSCFEAGDQGGTYNGNPLMTAAGIAVMRRLTAPGFL
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHH
DEVLARGDYLAARLRELVAKRHLVGERGSGLLRALVLDSDRAPAIVKAALEGAPTGLLLN
HHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHCCCCCCEEEE
APRPNLLRFMPSLTVSEAEIDQMVEMLDALLG
CCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]