BacMap

Definition	Azoarcus sp. BH72 chromosome, complete genome.
Accession	NC_008702
Length	4,376,040

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The map label for this gene is phbB1 [H]

Identifier: 119897313

GI number: 119897313

Start: 1098596

End: 1099336

Strand: Direct

Name: phbB1 [H]

Synonym: azo1022

Alternate gene names: 119897313

Gene position: 1098596-1099336 (Clockwise)

Preceding gene: 119897312

Following gene: 119897314

Centisome position: 25.1

GC content: 60.73

Gene sequence:

>741_bases
ATGTCTCGAGTCGCACTGGTTACTGGCGGGATGGGCGGACTGGGTGAAGCGATCTGCATCAAGCTCGCAGCACTCGGCTA
CCGTGTGGTGACCACCTACTCGCCCGGTAACAGCAAGGCTGCCGAATGGCTTCAGGCCATGAACAACATGGGCTACGGCT
TCAGGGGCTACCCCTGCGACGTGTCCGATTTCGATTCGTGCAAGGCCTGCATCGCGCAGGTCACCGAAGAGGTCGGTCCG
ATCGACGTGTTGGTGAACAACGCGGGTATTACCCGTGACATGACGTTCAAGAAGATGACCAAGGCCGACTGGGACGCGGT
GATCAGCACCAACCTGGATTCGGTGTTCAACATGACCAAGCAGGTCATGGACGGCATGGTCGAGCGCAAGTGGGGGCGGG
TGATCAACGTGTCGTCCGTCAATGGCCAGAAGGGAGCGTTCGGGCAGACGAACTACTCCGCCGCGAAGGCGGGTATGCAC
GGCTTCACCAAGGCGCTGGCACTGGAAGTCGCGCGCAGTGGCGTCACCGTCAATACCATCTCGCCGGGTTACATCGGTAC
CAAGATGGTGATGGCGATTCCCCAGGAGATCCTGGAGTCCAAGATCCTGCCGCAGATCCCGGTATCCCGCCTCGGCAAGC
CCGAGGAAATCGCCGGGCTGGTGGCGTATCTGTCGTCCGACGAGGCGGCTTTCGTAACCGGCGCCAACATCTCCATCAAC
GGCGGCCAGCACATGTTCTGA

Upstream 100 bases:

>100_bases
GGCGGAAAACCGGGATCTGGTCGACTGACGACGACGGGGAGGGCGCCGTCAGTCGAGCTTGCTACCCCCCCGAGACAACA
CAAGATAGAGGAGATAAACC

Downstream 100 bases:

>100_bases
TGTGCCGGCGGCGCCCGCCCCGCCCCCCGTGCGGGCGCAGGGCGCCGCCTTTTGCGCTGCAACAACCCCACTCGAACCTG
TTTATAATGCGCGCGGTAGT

Product: acetoacetyl-CoA reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSRVALVTGGMGGLGEAICIKLAALGYRVVTTYSPGNSKAAEWLQAMNNMGYGFRGYPCDVSDFDSCKACIAQVTEEVGP
IDVLVNNAGITRDMTFKKMTKADWDAVISTNLDSVFNMTKQVMDGMVERKWGRVINVSSVNGQKGAFGQTNYSAAKAGMH
GFTKALALEVARSGVTVNTISPGYIGTKMVMAIPQEILESKILPQIPVSRLGKPEEIAGLVAYLSSDEAAFVTGANISIN
GGQHMF

Sequences:

>Translated_246_residues
MSRVALVTGGMGGLGEAICIKLAALGYRVVTTYSPGNSKAAEWLQAMNNMGYGFRGYPCDVSDFDSCKACIAQVTEEVGP
IDVLVNNAGITRDMTFKKMTKADWDAVISTNLDSVFNMTKQVMDGMVERKWGRVINVSSVNGQKGAFGQTNYSAAKAGMH
GFTKALALEVARSGVTVNTISPGYIGTKMVMAIPQEILESKILPQIPVSRLGKPEEIAGLVAYLSSDEAAFVTGANISIN
GGQHMF
>Mature_245_residues
SRVALVTGGMGGLGEAICIKLAALGYRVVTTYSPGNSKAAEWLQAMNNMGYGFRGYPCDVSDFDSCKACIAQVTEEVGPI
DVLVNNAGITRDMTFKKMTKADWDAVISTNLDSVFNMTKQVMDGMVERKWGRVINVSSVNGQKGAFGQTNYSAAKAGMHG
FTKALALEVARSGVTVNTISPGYIGTKMVMAIPQEILESKILPQIPVSRLGKPEEIAGLVAYLSSDEAAFVTGANISING
GQHMF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=34.7826086956522, Blast_Score=151, Evalue=5e-37,
Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=32.3886639676113, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI4504505, Length=237, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=31.6205533596838, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=31.1475409836066, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=32.156862745098, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI5031737, Length=242, Percent_Identity=30.1652892561983, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7705925, Length=242, Percent_Identity=28.099173553719, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI66933014, Length=181, Percent_Identity=34.8066298342541, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI59889578, Length=194, Percent_Identity=32.4742268041237, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=25.4385964912281, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI83715985, Length=256, Percent_Identity=30.859375, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=27.3092369477912, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=29.5546558704453, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4503817, Length=226, Percent_Identity=29.646017699115, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=31.1881188118812, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7657478, Length=207, Percent_Identity=27.0531400966184, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI109715829, Length=241, Percent_Identity=27.3858921161826, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=31.0160427807487, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7706318, Length=191, Percent_Identity=28.2722513089005, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI20149619, Length=130, Percent_Identity=30.7692307692308, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI226371731, Length=257, Percent_Identity=28.7937743190661, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI150247226, Length=188, Percent_Identity=32.4468085106383, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=25.5208333333333, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI19743808, Length=190, Percent_Identity=30.5263157894737, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7705855, Length=197, Percent_Identity=30.9644670050761, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723191, Length=180, Percent_Identity=28.3333333333333, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=43.8524590163934, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=37.984496124031, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1790717, Length=238, Percent_Identity=31.9327731092437, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=31.1475409836066, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=32.6530612244898, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=29.6296296296296, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=30, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789057, Length=263, Percent_Identity=30.7984790874525, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1786812, Length=230, Percent_Identity=27.3913043478261, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367365, Length=240, Percent_Identity=30.4166666666667, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=27.8688524590164, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=26.984126984127, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=32.4324324324324, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786701, Length=192, Percent_Identity=26.0416666666667, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=41.869918699187, Blast_Score=173, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=39.1836734693878, Blast_Score=163, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=34.0163934426229, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17568967, Length=236, Percent_Identity=32.6271186440678, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=32.1138211382114, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538182, Length=255, Percent_Identity=32.156862745098, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.6818181818182, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=29.2592592592593, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=248, Percent_Identity=29.8387096774194, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=29.2, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=31.25, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=31.25, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=255, Percent_Identity=28.6274509803922, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=241, Percent_Identity=26.5560165975104, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=28.4644194756554, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=255, Percent_Identity=28.6274509803922, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.4090909090909, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=27.5862068965517, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561272, Length=193, Percent_Identity=30.5699481865285, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=25.4681647940075, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=29.2490118577075, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=24.5210727969349, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=260, Percent_Identity=27.6923076923077, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=268, Percent_Identity=27.9850746268657, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=27.4436090225564, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=25.7894736842105, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=197, Percent_Identity=25.8883248730964, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=26.9961977186312, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322861, Length=236, Percent_Identity=33.8983050847458, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324126, Length=244, Percent_Identity=27.4590163934426, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320089, Length=209, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=37.1428571428571, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI21357041, Length=253, Percent_Identity=33.201581027668, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=31.2252964426877, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=30.1652892561983, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=30.1652892561983, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=30.5555555555556, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI18859837, Length=234, Percent_Identity=34.1880341880342, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI17737361, Length=259, Percent_Identity=30.5019305019305, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644337, Length=184, Percent_Identity=34.7826086956522, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355631, Length=173, Percent_Identity=33.5260115606936, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24581726, Length=191, Percent_Identity=31.413612565445, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=29.0155440414508, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648693, Length=237, Percent_Identity=30.379746835443, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355889, Length=237, Percent_Identity=30.379746835443, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=27.8947368421053, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641388, Length=239, Percent_Identity=28.4518828451883, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24649181, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640442, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364892, Length=185, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007236, Length=233, Percent_Identity=27.4678111587983, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=28.9340101522843, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=28.9340101522843, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640492, Length=189, Percent_Identity=27.5132275132275, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI116007234, Length=235, Percent_Identity=28.5106382978723, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24641232, Length=213, Percent_Identity=28.169014084507, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.36 [H]

Molecular weight: Translated: 26179; Mature: 26047

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS00061 ADH_SHORT ; PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVALVTGGMGGLGEAICIKLAALGYRVVTTYSPGNSKAAEWLQAMNNMGYGFRGYPCD
CCCEEEEECCCCCCHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCC
VSDFDSCKACIAQVTEEVGPIDVLVNNAGITRDMTFKKMTKADWDAVISTNLDSVFNMTK
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
QVMDGMVERKWGRVINVSSVNGQKGAFGQTNYSAAKAGMHGFTKALALEVARSGVTVNTI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECC
SPGYIGTKMVMAIPQEILESKILPQIPVSRLGKPEEIAGLVAYLSSDEAAFVTGANISIN
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEC
GGQHMF
CCCCCC
>Mature Secondary Structure 
SRVALVTGGMGGLGEAICIKLAALGYRVVTTYSPGNSKAAEWLQAMNNMGYGFRGYPCD
CCEEEEECCCCCCHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCC
VSDFDSCKACIAQVTEEVGPIDVLVNNAGITRDMTFKKMTKADWDAVISTNLDSVFNMTK
CCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
QVMDGMVERKWGRVINVSSVNGQKGAFGQTNYSAAKAGMHGFTKALALEVARSGVTVNTI
HHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECC
SPGYIGTKMVMAIPQEILESKILPQIPVSRLGKPEEIAGLVAYLSSDEAAFVTGANISIN
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHCCCCEEEEECCEEEEC
GGQHMF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2670935 [H]