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The map label for this gene is dnaX [H]

Identifier: 119897248

GI number: 119897248

Start: 1029315

End: 1031303

Strand: Direct

Name: dnaX [H]

Synonym: azo0957

Alternate gene names: 119897248

Gene position: 1029315-1031303 (Clockwise)

Preceding gene: 119897243

Following gene: 119897249

Centisome position: 23.52

GC content: 70.74

Gene sequence:

>1989_bases
ATGAGCTACCAGGTCCTTGCACGCAAATGGCGGCCGAAATCCTTCGGCACGCTGGTCGGTCAGGAGCACGTCGTCCGTGC
GCTGAGCCACGCGCTCGCCACCGGCCGCCTGCACCATGCCTACCTGTTCACCGGTACGCGCGGGGTGGGCAAGACCACCA
TCAGCCGCATCCTGGCCAAAGCGCTCAACTGCGAAACCGGTGTGACGGCGGAGCCCTGCGGCCAGTGCGAAGCCTGCCGG
GCGATCGATGCGGACCGCTTCCCCGACTACGTGGAAATGGATGCCGCCTCCAACCGGGGCGTGGAAGACATGGCCGCGTT
GCTCGACAAGGCGGTATACGCGCCGGTGCAGGGCCGCTACAAGGTCTACATGATCGACGAAGTGCACATGCTCACCGGGC
ATGCGTTCAACGCGATGCTGAAGACCCTCGAAGAGCCGCCGGAGCACGTCAAGTTCATCCTCGCCACCACCGATCCGCAG
AAGATCCCGGTGACGGTGCTGTCACGCTGCCTGCAGTTCAACCTCAAGCAGATGCCGCAGGGGCATATCGTCGAGCACCT
GGACCGCGTCCTGACCGCCGAGGCGGTACCGTTCGAGCCGCCCGCGCTGCGGCATATCGCCAAAGCGGCCAACGGCTCGA
TGCGCGATGCCCTTTCGCTGCTCGATCAGGCGATCGCTCACGGCGCCGGCAAGGTGGCTGAAGAGCAGGTCACGCACATG
CTCGGCACTGTCGGTGATGATCACCTGCACGCCGTGCTGGAGGCGCTCGCCGCAGCCGACATGGCGGCGCTGCTCGCCGT
GGCCGACGGCATGGAGGCGCGCAGCCTCTCGTTCGACGCCGCGCTGCAGGCGCTGGCTTCACTGCTGCACCGGGTCGCGC
TCTATCAGTTTGCGCCGGCAGCGATTACCGACCCGCTCGAACGAAGCCGGGTCGAAGTCCACGCCGCGGCCTTCGACGCC
GAGTTTCTGCAGCTCGCCTACCAGATTGCGATCCATGGCCGGGAAGAGCTGCCGTTGGCGCCGGACGAATACACCGGCTT
CACGATGACGCTGCTGCGTCTGCACGCGTTCCGCCCGGAGCAGCCGCCGGCCTTGGGAAGCACGCCGACCGGCGCGGACG
GGGGCGCGGGGGGCGAGCGCCGGCCGCTGCCGGCGCGGGCGCCGGCTCCCGCCGCGGCGACGCCCCAGATGCAAAGCGCC
GGCGCCGGGCACCCGCCGAATGCGGTCGCGGCGACGAGCCGGCCCGTTCCGCCTGCGGCGACGACGGCCGCCCCGGCCCC
TGTGTCGGCCGCGCCTGTGCGGCAGGCACCGTCTTCCTTCGCCGCGCCCCCTGCGCCCGCAGCGCCGGTGGCGCCGCCCG
AGGGGCCGGCGGTTTCCCCGCCGGCGGGCGACGTTCCGCCGTGGGAGGAGCTGCCCCCGGAAGCGCAGTGGGACGAGGGT
GACAGGGCCGCAGCGGGCGGTGCCGAGCGCTTCGACGAGGAATTGAACGACGCGCCGCCGCGTCCGGCCCCGCTTGCGGT
CGTCAGACCCTCTACGGCGCCGGCGGTAGCACCCGCCGCGGACGAAGCACCCGGGGACGCCGTGCTGGCAGCCCCGCAGG
CGCTGGCGGCGGGCGACTGGCGGTCCCTGGTACGTGCCCTCGGGCTGACCGGCATGCTGCGGGAGCTGGCGCAGCACTGC
GAGTGGGTGGGGCTGGATGGCGAACAGCTCGAGCTGCGCCTGTCGGCCACCCATCGCCATCTGCTCGATATCAACCGCAG
CGCGCCCGAGCGGTTGCAGGAACAGCTCGGCGCCGCGTTGGGGCGCACGCTCCGGGTCCGGATCGTCATCGGTACCATCG
AGGGTGAGACGCCCGCCCAACGCGACGAAATCGAGCGTCGGCAGCGCCACGCCGAAGCGGTCGCGGCGCTCGAATGCGAC
CCCTTCGTGCGTGAATTGATCGAGCGCTTCGATGCCACGCTGCTCGAAGACACGGTACGGCCGCTCTAG

Upstream 100 bases:

>100_bases
GATAGACCAAATGGATTGAGCCAATCGCGCCGATTGGCAATTCGAATCATCGGCGGAGCGCGCCGGGAACGGGCAGGGGG
CTCTGCTAGAATCCCCACCC

Downstream 100 bases:

>100_bases
GCCTGCCCCCACGGCTAACCCATCCCTTCCTTCCCAGCGGAGAACATGATCATGATGAAAGGCGGTATTGCCGGCCTGAT
GAAGCAGGCCCAGCAGATGC

Product: DNA polymerase III subunit tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MSYQVLARKWRPKSFGTLVGQEHVVRALSHALATGRLHHAYLFTGTRGVGKTTISRILAKALNCETGVTAEPCGQCEACR
AIDADRFPDYVEMDAASNRGVEDMAALLDKAVYAPVQGRYKVYMIDEVHMLTGHAFNAMLKTLEEPPEHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPQGHIVEHLDRVLTAEAVPFEPPALRHIAKAANGSMRDALSLLDQAIAHGAGKVAEEQVTHM
LGTVGDDHLHAVLEALAAADMAALLAVADGMEARSLSFDAALQALASLLHRVALYQFAPAAITDPLERSRVEVHAAAFDA
EFLQLAYQIAIHGREELPLAPDEYTGFTMTLLRLHAFRPEQPPALGSTPTGADGGAGGERRPLPARAPAPAAATPQMQSA
GAGHPPNAVAATSRPVPPAATTAAPAPVSAAPVRQAPSSFAAPPAPAAPVAPPEGPAVSPPAGDVPPWEELPPEAQWDEG
DRAAAGGAERFDEELNDAPPRPAPLAVVRPSTAPAVAPAADEAPGDAVLAAPQALAAGDWRSLVRALGLTGMLRELAQHC
EWVGLDGEQLELRLSATHRHLLDINRSAPERLQEQLGAALGRTLRVRIVIGTIEGETPAQRDEIERRQRHAEAVAALECD
PFVRELIERFDATLLEDTVRPL

Sequences:

>Translated_662_residues
MSYQVLARKWRPKSFGTLVGQEHVVRALSHALATGRLHHAYLFTGTRGVGKTTISRILAKALNCETGVTAEPCGQCEACR
AIDADRFPDYVEMDAASNRGVEDMAALLDKAVYAPVQGRYKVYMIDEVHMLTGHAFNAMLKTLEEPPEHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPQGHIVEHLDRVLTAEAVPFEPPALRHIAKAANGSMRDALSLLDQAIAHGAGKVAEEQVTHM
LGTVGDDHLHAVLEALAAADMAALLAVADGMEARSLSFDAALQALASLLHRVALYQFAPAAITDPLERSRVEVHAAAFDA
EFLQLAYQIAIHGREELPLAPDEYTGFTMTLLRLHAFRPEQPPALGSTPTGADGGAGGERRPLPARAPAPAAATPQMQSA
GAGHPPNAVAATSRPVPPAATTAAPAPVSAAPVRQAPSSFAAPPAPAAPVAPPEGPAVSPPAGDVPPWEELPPEAQWDEG
DRAAAGGAERFDEELNDAPPRPAPLAVVRPSTAPAVAPAADEAPGDAVLAAPQALAAGDWRSLVRALGLTGMLRELAQHC
EWVGLDGEQLELRLSATHRHLLDINRSAPERLQEQLGAALGRTLRVRIVIGTIEGETPAQRDEIERRQRHAEAVAALECD
PFVRELIERFDATLLEDTVRPL
>Mature_661_residues
SYQVLARKWRPKSFGTLVGQEHVVRALSHALATGRLHHAYLFTGTRGVGKTTISRILAKALNCETGVTAEPCGQCEACRA
IDADRFPDYVEMDAASNRGVEDMAALLDKAVYAPVQGRYKVYMIDEVHMLTGHAFNAMLKTLEEPPEHVKFILATTDPQK
IPVTVLSRCLQFNLKQMPQGHIVEHLDRVLTAEAVPFEPPALRHIAKAANGSMRDALSLLDQAIAHGAGKVAEEQVTHML
GTVGDDHLHAVLEALAAADMAALLAVADGMEARSLSFDAALQALASLLHRVALYQFAPAAITDPLERSRVEVHAAAFDAE
FLQLAYQIAIHGREELPLAPDEYTGFTMTLLRLHAFRPEQPPALGSTPTGADGGAGGERRPLPARAPAPAAATPQMQSAG
AGHPPNAVAATSRPVPPAATTAAPAPVSAAPVRQAPSSFAAPPAPAAPVAPPEGPAVSPPAGDVPPWEELPPEAQWDEGD
RAAAGGAERFDEELNDAPPRPAPLAVVRPSTAPAVAPAADEAPGDAVLAAPQALAAGDWRSLVRALGLTGMLRELAQHCE
WVGLDGEQLELRLSATHRHLLDINRSAPERLQEQLGAALGRTLRVRIVIGTIEGETPAQRDEIERRQRHAEAVAALECDP
FVRELIERFDATLLEDTVRPL

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=287, Percent_Identity=24.0418118466899, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI194306571, Length=290, Percent_Identity=23.7931034482759, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI194306567, Length=290, Percent_Identity=23.7931034482759, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI31563534, Length=233, Percent_Identity=28.3261802575107, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1786676, Length=689, Percent_Identity=40.0580551523948, Blast_Score=429, Evalue=1e-121,
Organism=Escherichia coli, GI1787341, Length=161, Percent_Identity=32.9192546583851, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787119, Length=233, Percent_Identity=25.7510729613734, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17541988, Length=233, Percent_Identity=27.0386266094421, Blast_Score=67, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=259, Percent_Identity=25.0965250965251, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324478, Length=233, Percent_Identity=24.0343347639485, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI18859927, Length=331, Percent_Identity=23.8670694864048, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19921076, Length=303, Percent_Identity=24.0924092409241, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17647857, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 70495; Mature: 70364

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVLARKWRPKSFGTLVGQEHVVRALSHALATGRLHHAYLFTGTRGVGKTTISRILAK
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTAEPCGQCEACRAIDADRFPDYVEMDAASNRGVEDMAALLDKAVYAPVQGRY
HHCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCE
KVYMIDEVHMLTGHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPQ
EEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
GHIVEHLDRVLTAEAVPFEPPALRHIAKAANGSMRDALSLLDQAIAHGAGKVAEEQVTHM
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGTVGDDHLHAVLEALAAADMAALLAVADGMEARSLSFDAALQALASLLHRVALYQFAPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCH
AITDPLERSRVEVHAAAFDAEFLQLAYQIAIHGREELPLAPDEYTGFTMTLLRLHAFRPE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
QPPALGSTPTGADGGAGGERRPLPARAPAPAAATPQMQSAGAGHPPNAVAATSRPVPPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
TTAAPAPVSAAPVRQAPSSFAAPPAPAAPVAPPEGPAVSPPAGDVPPWEELPPEAQWDEG
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCC
DRAAAGGAERFDEELNDAPPRPAPLAVVRPSTAPAVAPAADEAPGDAVLAAPQALAAGDW
CCHHCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHH
RSLVRALGLTGMLRELAQHCEWVGLDGEQLELRLSATHRHLLDINRSAPERLQEQLGAAL
HHHHHHHCHHHHHHHHHHHCCEECCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHH
GRTLRVRIVIGTIEGETPAQRDEIERRQRHAEAVAALECDPFVRELIERFDATLLEDTVR
CCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
PL
CC
>Mature Secondary Structure 
SYQVLARKWRPKSFGTLVGQEHVVRALSHALATGRLHHAYLFTGTRGVGKTTISRILAK
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTAEPCGQCEACRAIDADRFPDYVEMDAASNRGVEDMAALLDKAVYAPVQGRY
HHCCCCCCCCCCCCCHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCCCE
KVYMIDEVHMLTGHAFNAMLKTLEEPPEHVKFILATTDPQKIPVTVLSRCLQFNLKQMPQ
EEEEEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
GHIVEHLDRVLTAEAVPFEPPALRHIAKAANGSMRDALSLLDQAIAHGAGKVAEEQVTHM
CHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGTVGDDHLHAVLEALAAADMAALLAVADGMEARSLSFDAALQALASLLHRVALYQFAPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCH
AITDPLERSRVEVHAAAFDAEFLQLAYQIAIHGREELPLAPDEYTGFTMTLLRLHAFRPE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
QPPALGSTPTGADGGAGGERRPLPARAPAPAAATPQMQSAGAGHPPNAVAATSRPVPPAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCC
TTAAPAPVSAAPVRQAPSSFAAPPAPAAPVAPPEGPAVSPPAGDVPPWEELPPEAQWDEG
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCC
DRAAAGGAERFDEELNDAPPRPAPLAVVRPSTAPAVAPAADEAPGDAVLAAPQALAAGDW
CCHHCCCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEECCHHHHHHHH
RSLVRALGLTGMLRELAQHCEWVGLDGEQLELRLSATHRHLLDINRSAPERLQEQLGAAL
HHHHHHHCHHHHHHHHHHHCCEECCCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHHHHH
GRTLRVRIVIGTIEGETPAQRDEIERRQRHAEAVAALECDPFVRELIERFDATLLEDTVR
CCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
PL
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]