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The map label for this gene is prpC [H]

Identifier: 119897187

GI number: 119897187

Start: 960324

End: 961154

Strand: Direct

Name: prpC [H]

Synonym: azo0896

Alternate gene names: 119897187

Gene position: 960324-961154 (Clockwise)

Preceding gene: 119897186

Following gene: 119897188

Centisome position: 21.95

GC content: 69.68

Gene sequence:

>831_bases
ATGGTAAGGCCAAGCAGGCGGGCGGCTTTCGCTTGCCATATCGGCGGACGCGCCGAACAGCAGGATCGTGCTGCGTGCTT
CACCAGCCGTGACGGCCGCAATCACCTGCTGGTCGTCGCCGACGGCATGGGCGGCCACCAAGGCGGTGAGCTGGCCTCGC
ACGTCGTCATGGAAGTGGCGGAGCGGGCGTGGTCGGCGCTCGACGGCCTGCCCCACGCCCCGGCGAGCTTTCTGGAACGT
GTGTGCCAGCAGGCCCATGCCGAAATCCGGCTGGCCGGCCAGGCGCGCGGACTGCGGCCGTGCTCCACGCTGGCGGCGCT
GCTGGTGTCGCCGCATCGCGCGTGGTGGAGCTATGTCGGCGACAGCCGCATCTATGTGTTCCGCGACGGTCGCCCGCTGT
GGCGCACCGAGGACCACACCGTCGTCCAGCAACTCGTGCGCAGCGGCCGCATCAGCGAAGCGGAGGTCGTCGATCACCCT
GATCGCAACAAGCTGCTGCGCGGCCTGGGGGGTGACGAGCCGCTGCGCGCCACCCATGGCCAGCTCCGCATCGACGCGGC
CACCGGCTTCGTGCTGTGCACCGACGGTTTCTGGGCGACGACGTCGACGGAAGAGATGGCCCCGCTGCTGAGCGCGTCCG
ACCTGGCTGCTGCGTGCACGAACGCCGTTGCAGCGGCGGCGCAGCGCGGCGGCCCCGAGAGCGACAACGTCACCATCGCC
GTGCTGCAGCCGGAACGGCGCACGCAGGCCGTGAACCATCGCCAGCTCTGGCCCTTGTACGGTGCGCTCGGGCTGGCGCT
GCTGCTGTTGTTTTCCCGCTTTTTCAATTGA

Upstream 100 bases:

>100_bases
CGGCCGGGTGGCGTGATATCGTCATGGCGCCCGGGCGCGGCAGCGTGCGGGTGCGGTCGCGCCGCTGCGACCGCCCCAGG
CGCCGATCACCGGAGGGGGG

Downstream 100 bases:

>100_bases
TGTCCGGTAACCATGGATAGAATCCCGCGCCTTGCGCCCTTCGTTTTCCTGCTCGCGCTACACGGCTGCGCCGGACTCGG
CAGCGGTGGGAACGGGACCG

Product: putative phosphoprotein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MVRPSRRAAFACHIGGRAEQQDRAACFTSRDGRNHLLVVADGMGGHQGGELASHVVMEVAERAWSALDGLPHAPASFLER
VCQQAHAEIRLAGQARGLRPCSTLAALLVSPHRAWWSYVGDSRIYVFRDGRPLWRTEDHTVVQQLVRSGRISEAEVVDHP
DRNKLLRGLGGDEPLRATHGQLRIDAATGFVLCTDGFWATTSTEEMAPLLSASDLAAACTNAVAAAAQRGGPESDNVTIA
VLQPERRTQAVNHRQLWPLYGALGLALLLLFSRFFN

Sequences:

>Translated_276_residues
MVRPSRRAAFACHIGGRAEQQDRAACFTSRDGRNHLLVVADGMGGHQGGELASHVVMEVAERAWSALDGLPHAPASFLER
VCQQAHAEIRLAGQARGLRPCSTLAALLVSPHRAWWSYVGDSRIYVFRDGRPLWRTEDHTVVQQLVRSGRISEAEVVDHP
DRNKLLRGLGGDEPLRATHGQLRIDAATGFVLCTDGFWATTSTEEMAPLLSASDLAAACTNAVAAAAQRGGPESDNVTIA
VLQPERRTQAVNHRQLWPLYGALGLALLLLFSRFFN
>Mature_276_residues
MVRPSRRAAFACHIGGRAEQQDRAACFTSRDGRNHLLVVADGMGGHQGGELASHVVMEVAERAWSALDGLPHAPASFLER
VCQQAHAEIRLAGQARGLRPCSTLAALLVSPHRAWWSYVGDSRIYVFRDGRPLWRTEDHTVVQQLVRSGRISEAEVVDHP
DRNKLLRGLGGDEPLRATHGQLRIDAATGFVLCTDGFWATTSTEEMAPLLSASDLAAACTNAVAAAAQRGGPESDNVTIA
VLQPERRTQAVNHRQLWPLYGALGLALLLLFSRFFN

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 30056; Mature: 30056

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRPSRRAAFACHIGGRAEQQDRAACFTSRDGRNHLLVVADGMGGHQGGELASHVVMEVA
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
ERAWSALDGLPHAPASFLERVCQQAHAEIRLAGQARGLRPCSTLAALLVSPHRAWWSYVG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCHHHHHHHCC
DSRIYVFRDGRPLWRTEDHTVVQQLVRSGRISEAEVVDHPDRNKLLRGLGGDEPLRATHG
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCC
QLRIDAATGFVLCTDGFWATTSTEEMAPLLSASDLAAACTNAVAAAAQRGGPESDNVTIA
EEEEEECCCEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VLQPERRTQAVNHRQLWPLYGALGLALLLLFSRFFN
EECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRPSRRAAFACHIGGRAEQQDRAACFTSRDGRNHLLVVADGMGGHQGGELASHVVMEVA
CCCCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHH
ERAWSALDGLPHAPASFLERVCQQAHAEIRLAGQARGLRPCSTLAALLVSPHRAWWSYVG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHCCHHHHHHHCC
DSRIYVFRDGRPLWRTEDHTVVQQLVRSGRISEAEVVDHPDRNKLLRGLGGDEPLRATHG
CCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCC
QLRIDAATGFVLCTDGFWATTSTEEMAPLLSASDLAAACTNAVAAAAQRGGPESDNVTIA
EEEEEECCCEEEEECCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
VLQPERRTQAVNHRQLWPLYGALGLALLLLFSRFFN
EECCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]