Click here to switch to the map view.

The map label for this gene is apaH [H]

Identifier: 119897144

GI number: 119897144

Start: 917838

End: 918635

Strand: Direct

Name: apaH [H]

Synonym: azo0853

Alternate gene names: 119897144

Gene position: 917838-918635 (Clockwise)

Preceding gene: 119897143

Following gene: 119897147

Centisome position: 20.97

GC content: 68.92

Gene sequence:

>798_bases
ATGGCGACCTACGCGATCGGCGACATCCAGGGCTGTTACGAGCCGTTGCGGCGGCTGCTCGATCTGATCCGCTTCGACCC
CGCGCACGATCGCCTGTGGGTGGTGGGCGATCTGGTCAACCGCGGCCCGGAATCCCTGATGGTGCTGCGCTACCTGCATG
AACTGGGCAGCGCAGCCACCGTGGTGCTCGGCAACCACGACCTCTATCTGCTGATGGTGGCCGCCGGGGTCGAGCGGCGC
GACAAGGACGACACGCTGTACCAGGTGCTGGAAGCGCCGGACCGCGACGTGCTGCTCGATTGGCTCGCGCGCCAGCCGCT
GCTGCACGTGGAGGGCGACCACGCGATGGTGCATGCCGGCCTGCTGCCGGTATGGACCATCACACGCGCGCAGGAACTCG
CAGCCGAGGTTTCGGCTGCGCTCACCGGTCCCGACGCGCGCCATTTCCTGCTCCACCTGGCCGGAAACCGGCCCGACCGC
TGGGCCGACAATCTGAAAGGCTGGGATCGCTTGCGGGTGATCGTCAATGCGATGACGCGGATGCGCTTCTGCACGCCCCA
CGGCCACCTCGCACTGCGCGCCAAGGGCCCGCCCGACGAGGCCCCGGCCGGCACGCTGCCCTGGTTTCGCGCCCCCGACC
GCTTCCACCGCACCCACACCATCGTCTGCGGGCACTGGTCGGCGCTGGGCTATTACCGGGGCGACGGCATCATCGCGCTG
GATTCCGGTTGCGTCTGGGGCGGCAAGCTGACCGCCTTCCGGCTGGAAGACGGTGAGGTGTTCCAGGTGCAGGGCTGA

Upstream 100 bases:

>100_bases
CGGGTTTGCGCCGGCAACCAGTGTCAGCGACGGCGTCGGCCGCTTCGTCGCCTGGTACCGCGCTTACTACGGCCTCTAAG
TCCGCGCTGAACGCCCGGCG

Downstream 100 bases:

>100_bases
GCCGCGCCGTCAGCGTACCTGTACCGCTTCCTGTGCCGCGGCGGGGGTCGCCGGCATTGCCGCGGCGCCCGTCTTGCGTT
CCATCTCTGTGCCGGCTTCC

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MATYAIGDIQGCYEPLRRLLDLIRFDPAHDRLWVVGDLVNRGPESLMVLRYLHELGSAATVVLGNHDLYLLMVAAGVERR
DKDDTLYQVLEAPDRDVLLDWLARQPLLHVEGDHAMVHAGLLPVWTITRAQELAAEVSAALTGPDARHFLLHLAGNRPDR
WADNLKGWDRLRVIVNAMTRMRFCTPHGHLALRAKGPPDEAPAGTLPWFRAPDRFHRTHTIVCGHWSALGYYRGDGIIAL
DSGCVWGGKLTAFRLEDGEVFQVQG

Sequences:

>Translated_265_residues
MATYAIGDIQGCYEPLRRLLDLIRFDPAHDRLWVVGDLVNRGPESLMVLRYLHELGSAATVVLGNHDLYLLMVAAGVERR
DKDDTLYQVLEAPDRDVLLDWLARQPLLHVEGDHAMVHAGLLPVWTITRAQELAAEVSAALTGPDARHFLLHLAGNRPDR
WADNLKGWDRLRVIVNAMTRMRFCTPHGHLALRAKGPPDEAPAGTLPWFRAPDRFHRTHTIVCGHWSALGYYRGDGIIAL
DSGCVWGGKLTAFRLEDGEVFQVQG
>Mature_264_residues
ATYAIGDIQGCYEPLRRLLDLIRFDPAHDRLWVVGDLVNRGPESLMVLRYLHELGSAATVVLGNHDLYLLMVAAGVERRD
KDDTLYQVLEAPDRDVLLDWLARQPLLHVEGDHAMVHAGLLPVWTITRAQELAAEVSAALTGPDARHFLLHLAGNRPDRW
ADNLKGWDRLRVIVNAMTRMRFCTPHGHLALRAKGPPDEAPAGTLPWFRAPDRFHRTHTIVCGHWSALGYYRGDGIIALD
SGCVWGGKLTAFRLEDGEVFQVQG

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=264, Percent_Identity=48.8636363636364, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843
- InterPro:   IPR006186 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 29658; Mature: 29527

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYAIGDIQGCYEPLRRLLDLIRFDPAHDRLWVVGDLVNRGPESLMVLRYLHELGSAAT
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCEE
VVLGNHDLYLLMVAAGVERRDKDDTLYQVLEAPDRDVLLDWLARQPLLHVEGDHAMVHAG
EEECCCCEEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCEEEEEC
LLPVWTITRAQELAAEVSAALTGPDARHFLLHLAGNRPDRWADNLKGWDRLRVIVNAMTR
CCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHH
MRFCTPHGHLALRAKGPPDEAPAGTLPWFRAPDRFHRTHTIVCGHWSALGYYRGDGIIAL
HEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCEEEEEEECHHCCCEEECCEEEEE
DSGCVWGGKLTAFRLEDGEVFQVQG
CCCEEECCCEEEEEECCCCEEEECC
>Mature Secondary Structure 
ATYAIGDIQGCYEPLRRLLDLIRFDPAHDRLWVVGDLVNRGPESLMVLRYLHELGSAAT
CCEECCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHCCCEE
VVLGNHDLYLLMVAAGVERRDKDDTLYQVLEAPDRDVLLDWLARQPLLHVEGDHAMVHAG
EEECCCCEEEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCEEEECCCCEEEEEC
LLPVWTITRAQELAAEVSAALTGPDARHFLLHLAGNRPDRWADNLKGWDRLRVIVNAMTR
CCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHH
MRFCTPHGHLALRAKGPPDEAPAGTLPWFRAPDRFHRTHTIVCGHWSALGYYRGDGIIAL
HEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHCCEEEEEEECHHCCCEEECCEEEEE
DSGCVWGGKLTAFRLEDGEVFQVQG
CCCEEECCCEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA