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The map label for this gene is ahpC [H]

Identifier: 119897060

GI number: 119897060

Start: 821109

End: 821672

Strand: Direct

Name: ahpC [H]

Synonym: azo0769

Alternate gene names: 119897060

Gene position: 821109-821672 (Clockwise)

Preceding gene: 119897059

Following gene: 119897061

Centisome position: 18.76

GC content: 60.11

Gene sequence:

>564_bases
ATGTCCCTGATCAACACCCAAGTCCAGCCTTTCAAAGCCCAAGCCTACAAGAACGGCAAGTTCATCGAAGTGACCGACGC
CGACCTGAAGGGCAAGTGGTCCGTGCTGATCTTCATGCCGGCCGCCTTCACCTTCAACTGCCCGACCGAAATCGAAGACG
CGGCTGAACACTATGCCGAGTTCGAGAAGGCCGGCGCCGAGGTGTACATCGTCACCACCGACACCCACTTCTCCCACAAG
GTGTGGCACGAAACCTCGCCCGCCGTGGGCAAGGCCAAGTTCGCGCTGGTTGGTGACCCGACCCACGCGCTGACCAACGC
TTTCGACGTGCATATCGCCGAAGAAGGCCTGGCGCTGCGCGGCACCTTCATCATCAACCCGGAAGGCGTCATCAAGACCA
TGGAAGTGCACGACAACGCTATCGCCCGCGATGTCACCGAAACCGTGCGCAAGCTGAAGGCCGCCCAATACGTTGCCTCG
CACCCGAACGAAGTCTGCCCGGCCAAGTGGAAGGAAGGCGAAAAGACGCTGGCTCCGTCCATCGACCTGGTTGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
ATCCTGATAATCAATTAGAGCAATTCAGGCCCCGGTCTTAAACTTCAGCCATAGAGTTTTTGTCACGCCGTTCCACTCAC
CCTGTTTTGGAGGATACGCA

Downstream 100 bases:

>100_bases
GCAGCCGCTGCAATCTGCCCGGGCCCATCCGGCCCGGGGCGATGTGCTCTGCAGCCGGCCATGCGCCGGCTGTGTCGTAT
CTGGCCGCCGAAAACACCGG

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLINTQVQPFKAQAYKNGKFIEVTDADLKGKWSVLIFMPAAFTFNCPTEIEDAAEHYAEFEKAGAEVYIVTTDTHFSHK
VWHETSPAVGKAKFALVGDPTHALTNAFDVHIAEEGLALRGTFIINPEGVIKTMEVHDNAIARDVTETVRKLKAAQYVAS
HPNEVCPAKWKEGEKTLAPSIDLVGKI

Sequences:

>Translated_187_residues
MSLINTQVQPFKAQAYKNGKFIEVTDADLKGKWSVLIFMPAAFTFNCPTEIEDAAEHYAEFEKAGAEVYIVTTDTHFSHK
VWHETSPAVGKAKFALVGDPTHALTNAFDVHIAEEGLALRGTFIINPEGVIKTMEVHDNAIARDVTETVRKLKAAQYVAS
HPNEVCPAKWKEGEKTLAPSIDLVGKI
>Mature_186_residues
SLINTQVQPFKAQAYKNGKFIEVTDADLKGKWSVLIFMPAAFTFNCPTEIEDAAEHYAEFEKAGAEVYIVTTDTHFSHKV
WHETSPAVGKAKFALVGDPTHALTNAFDVHIAEEGLALRGTFIINPEGVIKTMEVHDNAIARDVTETVRKLKAAQYVASH
PNEVCPAKWKEGEKTLAPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=43.0167597765363, Blast_Score=144, Evalue=5e-35,
Organism=Homo sapiens, GI5802974, Length=179, Percent_Identity=44.1340782122905, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=41.1428571428571, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=37.7142857142857, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=37.7142857142857, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=37.7142857142857, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=35.5555555555556, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI33188454, Length=77, Percent_Identity=46.7532467532467, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=60.9625668449198, Blast_Score=258, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=39.5480225988701, Blast_Score=135, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=36.7816091954023, Blast_Score=127, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=36.7816091954023, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=37.3626373626374, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=35.3591160220994, Blast_Score=126, Evalue=2e-30,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=39.5480225988701, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=36.8131868131868, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=36.8131868131868, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21357347, Length=182, Percent_Identity=34.6153846153846, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=38.2352941176471, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=38.2352941176471, Blast_Score=120, Evalue=4e-28,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20596; Mature: 20464

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTQVQPFKAQAYKNGKFIEVTDADLKGKWSVLIFMPAAFTFNCPTEIEDAAEHYAE
CCCCCCCCCCEEHHHCCCCCEEEEECCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHH
FEKAGAEVYIVTTDTHFSHKVWHETSPAVGKAKFALVGDPTHALTNAFDVHIAEEGLALR
HHHCCCEEEEEEECCCCCCCHHCCCCCCCCCEEEEEECCCHHHHHCCEEEEEECCCEEEE
GTFIINPEGVIKTMEVHDNAIARDVTETVRKLKAAQYVASHPNEVCPAKWKEGEKTLAPS
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
IDLVGKI
CCEEECC
>Mature Secondary Structure 
SLINTQVQPFKAQAYKNGKFIEVTDADLKGKWSVLIFMPAAFTFNCPTEIEDAAEHYAE
CCCCCCCCCEEHHHCCCCCEEEEECCCCCCCEEEEEEECCEEEECCCCCHHHHHHHHHH
FEKAGAEVYIVTTDTHFSHKVWHETSPAVGKAKFALVGDPTHALTNAFDVHIAEEGLALR
HHHCCCEEEEEEECCCCCCCHHCCCCCCCCCEEEEEECCCHHHHHCCEEEEEECCCEEEE
GTFIINPEGVIKTMEVHDNAIARDVTETVRKLKAAQYVASHPNEVCPAKWKEGEKTLAPS
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCC
IDLVGKI
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]