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The map label for this gene is nadA [H]

Identifier: 119897032

GI number: 119897032

Start: 791814

End: 792914

Strand: Direct

Name: nadA [H]

Synonym: azo0741

Alternate gene names: 119897032

Gene position: 791814-792914 (Clockwise)

Preceding gene: 119897031

Following gene: 119897033

Centisome position: 18.09

GC content: 64.58

Gene sequence:

>1101_bases
ATGCAAGTTGCCACCATCAGTTTCGACCGTTTCAATGCACTGCAGGACACCGAGGCGCAGGAGCGCATCCGTGCCGCGCG
CGCCCGACTGGGTGATCGCGCCGTGCTGCTGTGCCACCACTACCAGCGCGCCGATGTCTATCAGCACGCCGACCTCACCG
GCGACTCGCTGAAGCTCGCCCGGCTGGCCTCGCAGACTGATGCCGAGTACATCGTTTTCTGCGGCGTGCATTTCATGGCC
GAGGTGGCGGACATCCTGTCCAAGCCCAGCCAGATCGCCATCCTGCCGGACCTCGCGGCCGGCTGTTCGATGGCCGACAT
GGCCAATCTCGCCAAGGTGGAGCGCTGCTGGCGCGAACTGGGCGAGGTGCTGGACACGCCGGACGACCTGATCACCCCGG
TCACCTACATCAACTCGGCGGCCGATCTCAAGGCCTTCTGCGGTGAGCACGGCGGCATCGTGTGCACGTCCACCAACGCG
CCCACCATCCTCGACTGGGCCTTTGCGCAGCGCGAGAAGGTGTTGTTCTTCCCCGACCAGCACCTGGGCCGCTGGACCGG
CTACAAGAAGGGCATCCCGCTCGAGCAGATGGTGGTATGGGACCCCGATCTCGAATACGGCGGCCTTACCCCGGAGCAGA
TCCGCAACGCCAAGGTGCTGTTGTGGAAGGGCCACTGTTCGGTGCACCAGATGTTCCAGGAAAGCCACATCCGCCGCTGG
CGCATGCAGCATCCGGACGGGCTGGTCATCTCGCATCCGGAGAGCAGCCTGGAGGTGTGCCAGAACTCCGACTTCGTCGG
CTCCACCGAATACATCATCAAGACGATCGCGGCCGCGCCCGCCAATACCCGCTGGCTGGTGGGCACGGAACTGAACCTGG
TGAACCGGCTGGCCGAGGAAATGAAACCGGAAGGCAAGATCGTCCAGTTCATGGCGCCCACCGTCTGCATGTGCTCCACC
ATGCAGCGCATCGATCCGCAACATCTCGCGTGGACGCTGGAAAACCTGGCCGAGGGCAACGTGGTGAACCGCATCCAGGT
GCCGGCGCACGAGGCCGAACTCGCGCGCGTGGCGCTCGATCGTATGCTGGCGGTGTCCTGA

Upstream 100 bases:

>100_bases
CCGGGCTGCCCTGGCACCAGGGCTGATTCCGCCTTCGCGGGCGGGGCAACGCTGCTGTTGCCCCGTGGTCTGAAAGACAT
TCCGACAGAGCCGACGCACC

Downstream 100 bases:

>100_bases
CCATGTAAAGCGGAGGCGGCGATGGGCTTGCGGATCTGCACCTACAACATCCACAAGGGCTTTTCGCAGTTCAACCGGCG
CATGGTGGTGCACGACCTCC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQVATISFDRFNALQDTEAQERIRAARARLGDRAVLLCHHYQRADVYQHADLTGDSLKLARLASQTDAEYIVFCGVHFMA
EVADILSKPSQIAILPDLAAGCSMADMANLAKVERCWRELGEVLDTPDDLITPVTYINSAADLKAFCGEHGGIVCTSTNA
PTILDWAFAQREKVLFFPDQHLGRWTGYKKGIPLEQMVVWDPDLEYGGLTPEQIRNAKVLLWKGHCSVHQMFQESHIRRW
RMQHPDGLVISHPESSLEVCQNSDFVGSTEYIIKTIAAAPANTRWLVGTELNLVNRLAEEMKPEGKIVQFMAPTVCMCST
MQRIDPQHLAWTLENLAEGNVVNRIQVPAHEAELARVALDRMLAVS

Sequences:

>Translated_366_residues
MQVATISFDRFNALQDTEAQERIRAARARLGDRAVLLCHHYQRADVYQHADLTGDSLKLARLASQTDAEYIVFCGVHFMA
EVADILSKPSQIAILPDLAAGCSMADMANLAKVERCWRELGEVLDTPDDLITPVTYINSAADLKAFCGEHGGIVCTSTNA
PTILDWAFAQREKVLFFPDQHLGRWTGYKKGIPLEQMVVWDPDLEYGGLTPEQIRNAKVLLWKGHCSVHQMFQESHIRRW
RMQHPDGLVISHPESSLEVCQNSDFVGSTEYIIKTIAAAPANTRWLVGTELNLVNRLAEEMKPEGKIVQFMAPTVCMCST
MQRIDPQHLAWTLENLAEGNVVNRIQVPAHEAELARVALDRMLAVS
>Mature_366_residues
MQVATISFDRFNALQDTEAQERIRAARARLGDRAVLLCHHYQRADVYQHADLTGDSLKLARLASQTDAEYIVFCGVHFMA
EVADILSKPSQIAILPDLAAGCSMADMANLAKVERCWRELGEVLDTPDDLITPVTYINSAADLKAFCGEHGGIVCTSTNA
PTILDWAFAQREKVLFFPDQHLGRWTGYKKGIPLEQMVVWDPDLEYGGLTPEQIRNAKVLLWKGHCSVHQMFQESHIRRW
RMQHPDGLVISHPESSLEVCQNSDFVGSTEYIIKTIAAAPANTRWLVGTELNLVNRLAEEMKPEGKIVQFMAPTVCMCST
MQRIDPQHLAWTLENLAEGNVVNRIQVPAHEAELARVALDRMLAVS

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=360, Percent_Identity=28.0555555555556, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40962; Mature: 40962

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVATISFDRFNALQDTEAQERIRAARARLGDRAVLLCHHYQRADVYQHADLTGDSLKLA
CEEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCHHHHH
RLASQTDAEYIVFCGVHFMAEVADILSKPSQIAILPDLAAGCSMADMANLAKVERCWREL
HHHHCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECCHHCCCCHHHHHHHHHHHHHHHHH
GEVLDTPDDLITPVTYINSAADLKAFCGEHGGIVCTSTNAPTILDWAFAQREKVLFFPDQ
HHHHCCCHHHHCHHHHHCCHHHHHHHHCCCCCEEEECCCCCEEEEHHHHCCCEEEECCCH
HLGRWTGYKKGIPLEQMVVWDPDLEYGGLTPEQIRNAKVLLWKGHCSVHQMFQESHIRRW
HHHHHCCCCCCCCHHHEEEECCCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
RMQHPDGLVISHPESSLEVCQNSDFVGSTEYIIKTIAAAPANTRWLVGTELNLVNRLAEE
HCCCCCCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHH
MKPEGKIVQFMAPTVCMCSTMQRIDPQHLAWTLENLAEGNVVNRIQVPAHEAELARVALD
HCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
RMLAVS
HHHHCC
>Mature Secondary Structure
MQVATISFDRFNALQDTEAQERIRAARARLGDRAVLLCHHYQRADVYQHADLTGDSLKLA
CEEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCCCCHHHHH
RLASQTDAEYIVFCGVHFMAEVADILSKPSQIAILPDLAAGCSMADMANLAKVERCWREL
HHHHCCCCCEEEEEHHHHHHHHHHHHCCCCEEEEECCHHCCCCHHHHHHHHHHHHHHHHH
GEVLDTPDDLITPVTYINSAADLKAFCGEHGGIVCTSTNAPTILDWAFAQREKVLFFPDQ
HHHHCCCHHHHCHHHHHCCHHHHHHHHCCCCCEEEECCCCCEEEEHHHHCCCEEEECCCH
HLGRWTGYKKGIPLEQMVVWDPDLEYGGLTPEQIRNAKVLLWKGHCSVHQMFQESHIRRW
HHHHHCCCCCCCCHHHEEEECCCCCCCCCCHHHHCCCEEEEEECCHHHHHHHHHHHHHHH
RMQHPDGLVISHPESSLEVCQNSDFVGSTEYIIKTIAAAPANTRWLVGTELNLVNRLAEE
HCCCCCCEEEECCCHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHH
MKPEGKIVQFMAPTVCMCSTMQRIDPQHLAWTLENLAEGNVVNRIQVPAHEAELARVALD
HCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
RMLAVS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA