Click here to switch to the map view.

The map label for this gene is coaE [H]

Identifier: 119897022

GI number: 119897022

Start: 782235

End: 782855

Strand: Reverse

Name: coaE [H]

Synonym: azo0731

Alternate gene names: 119897022

Gene position: 782855-782235 (Counterclockwise)

Preceding gene: 119897023

Following gene: 119897021

Centisome position: 17.89

GC content: 68.44

Gene sequence:

>621_bases
GTGAAACGCCCCTACGTCGTCGGCCTGAGCGGAGGCATAGGCAGCGGCAAGAGCGCAGCGGCAGATCGCTTCGCCCACCT
GGGCGCCACGCTCGTCGATACCGATGCGATCGCACACGCGCTGACCGGCCCCGGCGGCGCGGCGATGCCGCAGATCGCCG
CACACTTCGGCTCAGCCTGTATCACCGCCGACGGCCGCATGGACCGTGAGGCGATGCGGGCGCTGGTCTTCTCCCGACCC
GCCGCCCGACGCGAACTGGAAGCCATCCTGCATCCGATGATCCGGACCGAAAGCGACCGCCAGGTGGCCGCTGCACCCAG
CCCCTACGTCATCCTCGCCATTCCCCTGCTCGTTGAATCCGGCACCGCCCGCGCGCGGTGCGACCGGATCTGCATCGTCG
ATTGCCCGGAAGCGTTGCAGATCGAACGGGTGCGGGCGCGAAGCGGGCTGGAGGAGGCGCAGATTCTCGCGATCATGCAG
GCACAGGCCAGCCGGGCGGAGCGCCTGGCCGTAGCCGACGACGTGATCGACAACAGCACGACCCTGAGCGCCTTGCATGC
ACAGGTGGATATCCTGCATGCGCGCTATCTCGCGCTCGCGGGCGATACCACCAAGGTCTAG

Upstream 100 bases:

>100_bases
CCCGCCTGGCTGTCACGCAGGCCGTCGATGCCATCGCCACGGAGGAACAATTGCGGCGTGTCGCGACCGGCCTCCCCGCT
GCGAACGCGACCTGCACGCC

Downstream 100 bases:

>100_bases
GCGGTGCAACGGCGGGCTGGCGACGCTGTGCTATCATCGACCGATTACTCTGGAGCGCCGGAATCTTGCGGACAAGACGC
GGTGATTAGCTACGAATACC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKRPYVVGLSGGIGSGKSAAADRFAHLGATLVDTDAIAHALTGPGGAAMPQIAAHFGSACITADGRMDREAMRALVFSRP
AARRELEAILHPMIRTESDRQVAAAPSPYVILAIPLLVESGTARARCDRICIVDCPEALQIERVRARSGLEEAQILAIMQ
AQASRAERLAVADDVIDNSTTLSALHAQVDILHARYLALAGDTTKV

Sequences:

>Translated_206_residues
MKRPYVVGLSGGIGSGKSAAADRFAHLGATLVDTDAIAHALTGPGGAAMPQIAAHFGSACITADGRMDREAMRALVFSRP
AARRELEAILHPMIRTESDRQVAAAPSPYVILAIPLLVESGTARARCDRICIVDCPEALQIERVRARSGLEEAQILAIMQ
AQASRAERLAVADDVIDNSTTLSALHAQVDILHARYLALAGDTTKV
>Mature_206_residues
MKRPYVVGLSGGIGSGKSAAADRFAHLGATLVDTDAIAHALTGPGGAAMPQIAAHFGSACITADGRMDREAMRALVFSRP
AARRELEAILHPMIRTESDRQVAAAPSPYVILAIPLLVESGTARARCDRICIVDCPEALQIERVRARSGLEEAQILAIMQ
AQASRAERLAVADDVIDNSTTLSALHAQVDILHARYLALAGDTTKV

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=33.160621761658, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=33.160621761658, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI110227607, Length=164, Percent_Identity=34.1463414634146, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI110227605, Length=164, Percent_Identity=34.1463414634146, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI110227603, Length=164, Percent_Identity=34.1463414634146, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI110227601, Length=164, Percent_Identity=34.1463414634146, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI205277394, Length=164, Percent_Identity=34.1463414634146, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1786292, Length=197, Percent_Identity=43.6548223350254, Blast_Score=161, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=30.6878306878307, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25143409, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=32.6530612244898, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24658602, Length=173, Percent_Identity=31.7919075144509, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24644728, Length=178, Percent_Identity=28.0898876404494, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21759; Mature: 21759

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPYVVGLSGGIGSGKSAAADRFAHLGATLVDTDAIAHALTGPGGAAMPQIAAHFGSAC
CCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEE
ITADGRMDREAMRALVFSRPAARRELEAILHPMIRTESDRQVAAAPSPYVILAIPLLVES
EECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEEHHCC
GTARARCDRICIVDCPEALQIERVRARSGLEEAQILAIMQAQASRAERLAVADDVIDNST
CCCHHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TLSALHAQVDILHARYLALAGDTTKV
HHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKRPYVVGLSGGIGSGKSAAADRFAHLGATLVDTDAIAHALTGPGGAAMPQIAAHFGSAC
CCCCEEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEE
ITADGRMDREAMRALVFSRPAARRELEAILHPMIRTESDRQVAAAPSPYVILAIPLLVES
EECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEEEHHCC
GTARARCDRICIVDCPEALQIERVRARSGLEEAQILAIMQAQASRAERLAVADDVIDNST
CCCHHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
TLSALHAQVDILHARYLALAGDTTKV
HHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA