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The map label for this gene is visC [H]

Identifier: 119897014

GI number: 119897014

Start: 776049

End: 777212

Strand: Direct

Name: visC [H]

Synonym: azo0723

Alternate gene names: 119897014

Gene position: 776049-777212 (Clockwise)

Preceding gene: 119897013

Following gene: 119897015

Centisome position: 17.73

GC content: 62.37

Gene sequence:

>1164_bases
ATGAATTTCGACGTAGTGGTTGTGGGCGGAGGATTGGCTGGTGCCGCGCTTACGGTTGCGCTTCGCGCGAGCAGTTTGCG
GGTGGCAGTTGTCGATGCTGGATTGCCGACTCCCAGCCAGGGCTGGGATTCGAGAATTTATGCTTACAGTCCAGCGAGCG
CCGACTTTCTGGGGACGCTGGGTGTCTGGCAGCATCTTGACGCCGACCGCCTGTGTCCCGTTCATTCCATGGACGTGCGT
GGCGACGACGGCGGTCGTTTGCGATTCGATGCGGCTGGGTGTGGATTGCGCGAACTCGCTTGGATTGGAGAGTCCAGCCT
CGTTCATCGCGAACTGTGGGAGTCACTCAAGCGGCAGCATAACGTCACGGTATTTGCGCCGGCCCGGCCGACTGCGCTGA
CGGTTTCCGGGAACGACGCCGCACTGGAGCTTGAGGATGGTCGCCTGCTGCATACGCGACTGCTTGTCGGTGCAGATGGG
CGTGACTCCTGGGTTCGTAGCCAGACCGCCATCAAAGCCTCGTCGGTCAATTATGAAGAGACGGCAGTGGTGGCCAATTT
TTCGTGTGAACGCCCTCATCGAAACGAAGCCTTGCAGTGGTTCACTGACGAAGGCGTGGTCGCGTGGTTGCCGTTGCCGG
GGCGGATGATGTCGTTGGTATGGTCGGCACCTGCCGCTCTGGCGGAAACGCTCATGGCCATGACGCCAGAACAGTTCACG
CGGCGAGTCCAGGAGCGGGGCGGGGCCGCGTGGGGCCGGTTGTCGGTGGTGACGCCGCCCGCCGCATTTCCGCTTCGTTT
CATGCGACTCGACCGCGTCGTAGCGTCTCGGGTTGCCTTGATCGGTGATGCAGCACACGCGATTCATCCGCTGTCGGGGC
ATGGCATCAATCTTGGATTTCAGGACGCGCGGGTGTTGAGCCAGAGGCTGCTTTCCGCGCCCGCCTGGGCCGACCCGGGC
GACGAGCGCCTGTTGAGGTCCTATGCTAGAGAGCGGGCGGAAGAGCCGTTTCTGGTGCAGTACGTGACGCACGGAATCAA
CCGTCTGTTCGCGGCCCGGAATCCGCTGGCGGCGTTCGTCCGCAACCTCGGTCTGAACCTTACGGACCGTCTGCCGGTCG
TAAGGTCCGCGCTGACGCGTTACGCGGTGCATGGAAAGTTTTGA

Upstream 100 bases:

>100_bases
GCCTCCCCTGCTCGAAGCCCCGTTCCTGACGTGATCGAGGGCTGACGTCGGCGCGCAGGCAGGGCACAATCAAACCTGCC
AAATACTGTCAGCGACGATG

Downstream 100 bases:

>100_bases
CAAGGAGAACTGGATGGTGGCGTTGAAATCCGCGGGCCGATTCGCGCTCGTTATTGCGTTCGGATTGCTTCCGACGCTTG
TTGCAGCCGGCGAGGAAGAT

Product: ubiquinone biosynthesis hydroxylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MNFDVVVVGGGLAGAALTVALRASSLRVAVVDAGLPTPSQGWDSRIYAYSPASADFLGTLGVWQHLDADRLCPVHSMDVR
GDDGGRLRFDAAGCGLRELAWIGESSLVHRELWESLKRQHNVTVFAPARPTALTVSGNDAALELEDGRLLHTRLLVGADG
RDSWVRSQTAIKASSVNYEETAVVANFSCERPHRNEALQWFTDEGVVAWLPLPGRMMSLVWSAPAALAETLMAMTPEQFT
RRVQERGGAAWGRLSVVTPPAAFPLRFMRLDRVVASRVALIGDAAHAIHPLSGHGINLGFQDARVLSQRLLSAPAWADPG
DERLLRSYARERAEEPFLVQYVTHGINRLFAARNPLAAFVRNLGLNLTDRLPVVRSALTRYAVHGKF

Sequences:

>Translated_387_residues
MNFDVVVVGGGLAGAALTVALRASSLRVAVVDAGLPTPSQGWDSRIYAYSPASADFLGTLGVWQHLDADRLCPVHSMDVR
GDDGGRLRFDAAGCGLRELAWIGESSLVHRELWESLKRQHNVTVFAPARPTALTVSGNDAALELEDGRLLHTRLLVGADG
RDSWVRSQTAIKASSVNYEETAVVANFSCERPHRNEALQWFTDEGVVAWLPLPGRMMSLVWSAPAALAETLMAMTPEQFT
RRVQERGGAAWGRLSVVTPPAAFPLRFMRLDRVVASRVALIGDAAHAIHPLSGHGINLGFQDARVLSQRLLSAPAWADPG
DERLLRSYARERAEEPFLVQYVTHGINRLFAARNPLAAFVRNLGLNLTDRLPVVRSALTRYAVHGKF
>Mature_387_residues
MNFDVVVVGGGLAGAALTVALRASSLRVAVVDAGLPTPSQGWDSRIYAYSPASADFLGTLGVWQHLDADRLCPVHSMDVR
GDDGGRLRFDAAGCGLRELAWIGESSLVHRELWESLKRQHNVTVFAPARPTALTVSGNDAALELEDGRLLHTRLLVGADG
RDSWVRSQTAIKASSVNYEETAVVANFSCERPHRNEALQWFTDEGVVAWLPLPGRMMSLVWSAPAALAETLMAMTPEQFT
RRVQERGGAAWGRLSVVTPPAAFPLRFMRLDRVVASRVALIGDAAHAIHPLSGHGINLGFQDARVLSQRLLSAPAWADPG
DERLLRSYARERAEEPFLVQYVTHGINRLFAARNPLAAFVRNLGLNLTDRLPVVRSALTRYAVHGKF

Specific function: Not yet known [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=405, Percent_Identity=27.9012345679012, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI32967307, Length=276, Percent_Identity=30.7971014492754, Blast_Score=109, Evalue=5e-24,
Organism=Escherichia coli, GI1789273, Length=388, Percent_Identity=35.0515463917526, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1786883, Length=387, Percent_Identity=32.0413436692506, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1789274, Length=387, Percent_Identity=30.2325581395349, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI25146631, Length=433, Percent_Identity=31.1778290993072, Blast_Score=164, Evalue=9e-41,
Organism=Saccharomyces cerevisiae, GI6321694, Length=444, Percent_Identity=25.6756756756757, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19920760, Length=430, Percent_Identity=29.7674418604651, Blast_Score=166, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 42236; Mature: 42236

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDVVVVGGGLAGAALTVALRASSLRVAVVDAGLPTPSQGWDSRIYAYSPASADFLGTL
CCEEEEEECCCHHHHHHHHEEECCCEEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHH
GVWQHLDADRLCPVHSMDVRGDDGGRLRFDAAGCGLRELAWIGESSLVHRELWESLKRQH
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHC
NVTVFAPARPTALTVSGNDAALELEDGRLLHTRLLVGADGRDSWVRSQTAIKASSVNYEE
CEEEEECCCCEEEEEECCCEEEEECCCEEEEEEEEEECCCCCHHHHHHHHEEECCCCCCC
TAVVANFSCERPHRNEALQWFTDEGVVAWLPLPGRMMSLVWSAPAALAETLMAMTPEQFT
EEEEEECCCCCCCCCCHHEEECCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHCCHHHHH
RRVQERGGAAWGRLSVVTPPAAFPLRFMRLDRVVASRVALIGDAAHAIHPLSGHGINLGF
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCC
QDARVLSQRLLSAPAWADPGDERLLRSYARERAEEPFLVQYVTHGINRLFAARNPLAAFV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHH
RNLGLNLTDRLPVVRSALTRYAVHGKF
HHCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNFDVVVVGGGLAGAALTVALRASSLRVAVVDAGLPTPSQGWDSRIYAYSPASADFLGTL
CCEEEEEECCCHHHHHHHHEEECCCEEEEEEECCCCCCCCCCCCEEEEECCCCCHHHHHH
GVWQHLDADRLCPVHSMDVRGDDGGRLRFDAAGCGLRELAWIGESSLVHRELWESLKRQH
HHHHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHHHHC
NVTVFAPARPTALTVSGNDAALELEDGRLLHTRLLVGADGRDSWVRSQTAIKASSVNYEE
CEEEEECCCCEEEEEECCCEEEEECCCEEEEEEEEEECCCCCHHHHHHHHEEECCCCCCC
TAVVANFSCERPHRNEALQWFTDEGVVAWLPLPGRMMSLVWSAPAALAETLMAMTPEQFT
EEEEEECCCCCCCCCCHHEEECCCCEEEEECCCHHHHHHHHCCHHHHHHHHHHCCHHHHH
RRVQERGGAAWGRLSVVTPPAAFPLRFMRLDRVVASRVALIGDAAHAIHPLSGHGINLGF
HHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCC
QDARVLSQRLLSAPAWADPGDERLLRSYARERAEEPFLVQYVTHGINRLFAARNPLAAFV
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCHHHHHH
RNLGLNLTDRLPVVRSALTRYAVHGKF
HHCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on paired donors, with incorporation or reduction of molecular oxygen; With NADH2 or NADPH2 as one donor, and incorporation of one atom of oxygen [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]